ES2005160A6 - Un metodo para preparar derivados de moranolina. - Google Patents
Un metodo para preparar derivados de moranolina.Info
- Publication number
- ES2005160A6 ES2005160A6 ES8701085A ES8701085A ES2005160A6 ES 2005160 A6 ES2005160 A6 ES 2005160A6 ES 8701085 A ES8701085 A ES 8701085A ES 8701085 A ES8701085 A ES 8701085A ES 2005160 A6 ES2005160 A6 ES 2005160A6
- Authority
- ES
- Spain
- Prior art keywords
- manufacturing
- methanol
- moranoline derivatives
- moranoline
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
UN METODO PARA PREPARAR DERIVADOS DE MORANOLINA DE FORMULAEN EL QUE SE CALIENTA EN AGUA, O SE DISUELVE EN AGUA A TEMPERATURA AMBIENTE, UNA MEZCLA DEL DERIVADO DE FORMULA (I), OLIGOGLUCOSILMORANOLINA DE FORMULAEN LA QUE N ES 1 A 5, Y MORANOLINA DE FORMULASE AÑADE METANOL EN UNA CANTIDAD DE 1 A 1.000 VECES EL VOLUMEN DE LA MEZCLA, SE MANTIENE ESTA A UNA TEMPERATURA DE 5 A 40GC CON AGITACION A UNA VELOCIDAD DE 50 A 1.000 RPM DURANTE 30 MINUTOS A 72 HORAS, Y SE APLICA CRISTALIZACION FRACCIONADA A LA MEZCLA PARA SEPARAR EL COMPUESTO BUSCADO. EL DERIVADO DE GLUCOSILMORANOLINA CON MATANOL RESULTANTE PUEDE TRATARSE SEGUIDAMENTE CON ETANOL, PROPORCIONANDO OTRO DERIVADO DE MORANOLINA. LOS DERIVADOS OBTENIDOS SON ESPECIALMENTE UTILES COMO AGENTES TERAPEUTICOS PARA LA DIABETES MELITUS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP61087509A JPS62242692A (ja) | 1986-04-15 | 1986-04-15 | モラノリン誘導体の製造法 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2005160A6 true ES2005160A6 (es) | 1989-03-01 |
Family
ID=13916951
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8701085A Expired ES2005160A6 (es) | 1986-04-15 | 1987-04-14 | Un metodo para preparar derivados de moranolina. |
Country Status (13)
Country | Link |
---|---|
US (1) | US4806633A (es) |
JP (1) | JPS62242692A (es) |
KR (1) | KR950004899B1 (es) |
AT (1) | AT392474B (es) |
BE (1) | BE1000157A5 (es) |
CH (1) | CH671766A5 (es) |
DE (1) | DE3712799A1 (es) |
ES (1) | ES2005160A6 (es) |
FR (1) | FR2601019B1 (es) |
GB (1) | GB2190081B (es) |
IT (1) | IT1206061B (es) |
NL (1) | NL8700731A (es) |
SE (1) | SE469941B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991018915A1 (en) * | 1990-06-08 | 1991-12-12 | Merrell Dow Pharmaceuticals Inc. | NOVEL α-GLUCOSIDASE INHIBITORS |
US5504078A (en) * | 1990-06-08 | 1996-04-02 | Merrell Dow Pharmaceuticals Inc. | α-glucosidase inhibitors |
CA2106301C (en) * | 1991-03-18 | 1999-04-06 | Chi-Huey Wong | Oligosaccharide enzyme substrates and inhibitors: method and compositions |
CA2129140A1 (en) * | 1992-01-31 | 1993-08-05 | Akira Hasegawa | Lewis-type sugar chain derivative |
US8579029B2 (en) * | 2008-12-31 | 2013-11-12 | Schlumberger Technology Corporation | System, method and treatment fluid for controlling fines migration |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2832268A1 (de) * | 1978-07-22 | 1980-01-31 | Bayer Ag | Pseudotrisaccharide |
GB2064527B (en) * | 1979-12-08 | 1984-05-02 | Nippon Shinyaku Co Ltd | Moranoline derivatives and process for preparation thereof |
JPS5681595A (en) * | 1979-12-08 | 1981-07-03 | Nippon Shinyaku Co Ltd | Moranoline derivative and its preparation |
JPS602038B2 (ja) * | 1980-09-22 | 1985-01-18 | 日本新薬株式会社 | グルコシルモラノリン誘導体の製法 |
JPS56108767A (en) * | 1980-01-28 | 1981-08-28 | Nippon Shinyaku Co Ltd | Bismoranoline derivative |
JPS56108768A (en) * | 1980-01-28 | 1981-08-28 | Nippon Shinyaku Co Ltd | Cinnamylmoranoline derivative |
JPS6055078B2 (ja) * | 1980-12-01 | 1985-12-03 | 日本新薬株式会社 | モラノリンの誘導体 |
US4526784A (en) * | 1981-05-05 | 1985-07-02 | Bayer Aktiengesellschaft | Amino-cyclitol derivatives and medicaments containing them |
JPS61115093A (ja) * | 1984-11-09 | 1986-06-02 | Nippon Shinyaku Co Ltd | モラノリン誘導体の製法 |
US4634765A (en) * | 1984-12-18 | 1987-01-06 | Merrell Dow Pharmaceuticals Inc. | Homodisaccharide hypoglycemic agents |
-
1986
- 1986-04-15 JP JP61087509A patent/JPS62242692A/ja active Pending
-
1987
- 1987-03-30 SE SE8701317A patent/SE469941B/sv not_active IP Right Cessation
- 1987-03-30 NL NL8700731A patent/NL8700731A/nl not_active Application Discontinuation
- 1987-03-31 IT IT8747798A patent/IT1206061B/it active
- 1987-04-06 GB GB8708193A patent/GB2190081B/en not_active Expired - Fee Related
- 1987-04-13 CH CH1429/87A patent/CH671766A5/fr not_active IP Right Cessation
- 1987-04-14 ES ES8701085A patent/ES2005160A6/es not_active Expired
- 1987-04-14 FR FR878705285A patent/FR2601019B1/fr not_active Expired
- 1987-04-15 DE DE19873712799 patent/DE3712799A1/de active Granted
- 1987-04-15 BE BE8700405A patent/BE1000157A5/fr not_active IP Right Cessation
- 1987-04-15 KR KR1019870003583A patent/KR950004899B1/ko active IP Right Grant
- 1987-04-15 US US07/039,012 patent/US4806633A/en not_active Expired - Fee Related
- 1987-04-15 AT AT955/87A patent/AT392474B/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
GB2190081A (en) | 1987-11-11 |
IT8747798A0 (it) | 1987-03-31 |
NL8700731A (nl) | 1987-11-02 |
FR2601019B1 (fr) | 1989-05-05 |
SE469941B (sv) | 1993-10-11 |
DE3712799A1 (de) | 1987-10-22 |
GB8708193D0 (en) | 1987-05-13 |
SE8701317D0 (sv) | 1987-03-30 |
DE3712799C2 (es) | 1989-04-06 |
ATA95587A (de) | 1990-09-15 |
AT392474B (de) | 1991-04-10 |
JPS62242692A (ja) | 1987-10-23 |
IT1206061B (it) | 1989-04-14 |
CH671766A5 (es) | 1989-09-29 |
BE1000157A5 (fr) | 1988-06-28 |
SE8701317L (sv) | 1987-10-16 |
KR950004899B1 (ko) | 1995-05-15 |
GB2190081B (en) | 1990-03-21 |
FR2601019A1 (fr) | 1988-01-08 |
KR870010070A (ko) | 1987-11-30 |
US4806633A (en) | 1989-02-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19990201 |