ES2001788A6 - Un metodo para producir proteinas heterologas - Google Patents

Un metodo para producir proteinas heterologas

Info

Publication number
ES2001788A6
ES2001788A6 ES8601951A ES8601951A ES2001788A6 ES 2001788 A6 ES2001788 A6 ES 2001788A6 ES 8601951 A ES8601951 A ES 8601951A ES 8601951 A ES8601951 A ES 8601951A ES 2001788 A6 ES2001788 A6 ES 2001788A6
Authority
ES
Spain
Prior art keywords
promoter
pho5
heterologous proteins
miniaturized
producing heterologous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8601951A
Other languages
English (en)
Inventor
Hajime Horii
Hiromichi Mukai
Muneo Tsujikawa
Haruhide Kawabe
Hirofumi Arimura
Tadakazu Suyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Green Cross Corp Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP61077422A external-priority patent/JPS62151183A/ja
Application filed by Green Cross Corp Japan filed Critical Green Cross Corp Japan
Publication of ES2001788A6 publication Critical patent/ES2001788A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

UN METODO PARA PRODUCIR PROTEINAS HETEROLOGAS EN EL QUE SE UTILIZA COMO PROMOTOR UNA SECUENCIA DE ADN QUE COMPRENDE LA REGION DEL PROMOTOR (PH05) DE FOSFATASA ACIDA REPRIMIBLE DE LEVADURA QUE ABARCA LOS 173 PARES DE BASES JUSTO AGUAS ARRIBA A PARTIR DEL CORDON DE INICIACION PARA LA PROTEINA PH05. DICHO PROMOTOR SE PUEDE EMPLEAR INSERTADO EN UN PLASMIDO RECOMBINANTE SUSCEPTIBLE DE TRANSFORMAR UNA CEPA DE LEVADURA Y ORIGINAR ADEMAS LA EXPRESION DEL GEN QUE CONTIENE DICHO PLASMIDO. EL INVENTO ES ESPECIALMENTE UTIL PARA LA OBTENCION DEL ANTIGENO DE SUPERFICIE DE LA HEPATITIS B(HBSAG).
ES8601951A 1985-09-18 1986-09-17 Un metodo para producir proteinas heterologas Expired ES2001788A6 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20582385 1985-09-18
JP61077422A JPS62151183A (ja) 1985-09-18 1986-04-03 酵母プロモ−タ−及び異種蛋白質の製造方法

Publications (1)

Publication Number Publication Date
ES2001788A6 true ES2001788A6 (es) 1988-06-16

Family

ID=26418505

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8601951A Expired ES2001788A6 (es) 1985-09-18 1986-09-17 Un metodo para producir proteinas heterologas

Country Status (3)

Country Link
EP (1) EP0216573B1 (es)
DE (1) DE3675724D1 (es)
ES (1) ES2001788A6 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2791418B2 (ja) 1987-12-02 1998-08-27 株式会社ミドリ十字 異種蛋白質の製造方法、組換えｄｎａ、形質転換体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides
EP0143081B1 (en) * 1983-11-21 1989-08-23 Ciba-Geigy Ag Synthesis of tissue plasminogen activator(tpa) by yeast

Also Published As

Publication number Publication date
EP0216573B1 (en) 1990-11-22
EP0216573A1 (en) 1987-04-01
DE3675724D1 (de) 1991-01-03

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2006-09-17

FD1A Patent lapsed

Effective date: 20000208