ES2000716A6 - Un procedimiento para preparar derivados de tetrahidroisoquinoleina - Google Patents

Un procedimiento para preparar derivados de tetrahidroisoquinoleina

Info

Publication number
ES2000716A6
ES2000716A6 ES8600470A ES8600470A ES2000716A6 ES 2000716 A6 ES2000716 A6 ES 2000716A6 ES 8600470 A ES8600470 A ES 8600470A ES 8600470 A ES8600470 A ES 8600470A ES 2000716 A6 ES2000716 A6 ES 2000716A6
Authority
ES
Spain
Prior art keywords
preparation
compositions containing
intermediates
pharmaceutical compositions
tetrahydroisoquinoline derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600470A
Other languages
English (en)
Inventor
Carl Kaiser
Lawrence Ivan Kruse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of ES2000716A6 publication Critical patent/ES2000716A6/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • C07D217/20Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

EL PROCEDIMIENTO DESCRITO PREPARA COMPUESTOS DE FORMULA EN LA QUE Y ES HIDROXILO; X1 ES ALCOXILO DE C1-4; M ES 1 A 3; Y X2 ES ALCOXILO DE C1-4, HALOGENO, CF3 O ALQUILO DE C1-4, SIEMPRE QUE: I) CUANDO M ES 1, X2 ES CF3, HALOGENO O ALQUILO DE C1-4; E II) CUANDO M ES 2 O 3, AL MENOS UN X2 ES ALCOXILO DE C1-4, O SUS SALES DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLES, REDUCIENDO UN COMPUESTO CORRESPONDIENTE (II) DESHIDROGENADO EN EL ANILLO DE ISOQUINOLEINA O HACIENDO REACCIONAR UNA AMINA (III) CON UN ALDEHIDO (IV) (LAS F''ORMULAS II-IV FIGURAN EN LA MEMORIA). LOS COMPUESTOS OBTENIDOS SON UTILES COMO ANTAGONISTAS DE RECEPTORES B-ADRENERGICOS Y SE EMPLEAN EN COMPOSICIONES FARMACEUTICAS DOTADAS DE DICHA ACTIVIDAD TERAPEUTICA.
ES8600470A 1985-07-23 1986-07-22 Un procedimiento para preparar derivados de tetrahidroisoquinoleina Expired ES2000716A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858518635A GB8518635D0 (en) 1985-07-23 1985-07-23 Chemical compounds

Publications (1)

Publication Number Publication Date
ES2000716A6 true ES2000716A6 (es) 1988-03-16

Family

ID=10582747

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8600470A Expired ES2000716A6 (es) 1985-07-23 1986-07-22 Un procedimiento para preparar derivados de tetrahidroisoquinoleina

Country Status (9)

Country Link
EP (1) EP0210828A3 (es)
JP (1) JPS6222769A (es)
AU (1) AU586005B2 (es)
DK (1) DK346286A (es)
ES (1) ES2000716A6 (es)
GB (1) GB8518635D0 (es)
GR (1) GR861875B (es)
PT (1) PT83008A (es)
ZA (1) ZA865461B (es)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE352889B (es) * 1968-01-31 1973-01-15 Tanabe Seiyaku Co

Also Published As

Publication number Publication date
GR861875B (en) 1986-11-24
DK346286A (da) 1987-01-24
ZA865461B (en) 1987-04-29
EP0210828A2 (en) 1987-02-04
AU586005B2 (en) 1989-06-29
PT83008A (en) 1986-08-01
DK346286D0 (da) 1986-07-21
AU6023586A (en) 1987-01-29
GB8518635D0 (en) 1985-08-29
JPS6222769A (ja) 1987-01-30
EP0210828A3 (en) 1988-03-16

Similar Documents

Publication Publication Date Title
ES8603477A1 (es) Procedimiento para preparar una 1h-imidazo (4, 5-c) quinolin-4-amina
IL67572A0 (en) New derivatives of bicyclic aminoacids,processes for their preparation,agents containing these compounds and their use,and new bicyclic aminoacids as intermediates and processes for their preparation
IL77396A (en) Pharmaceutical compositions containing bicyclic heteroarylpiperazine derivatives,certain such novel compounds and their preparation
ES8706132A1 (es) Un procedimiento para la preparacion de analogos de benzodiazepina
NZ221226A (en) Nasal pharmaceutical compositions of serotonin antagonists
ES531981A0 (es) Un procedimiento para preparar pirazolo (4,3-c) piridinas
JO1351B1 (en) Chemical compounds
ZA831989B (en) New derivatives of bicyclic aminoacids,processes for their preparation,agents containing these derivatives and their use and new bicyclic aminoacids as intermediates and processes for their preparation
MY102038A (en) 4-substituted androstendione derivatives and process for their preparation
DE3571982D1 (en) Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds
PT77370B (en) Process for preparing new pyrazolo <3,4-b> piridine derivatives and pharmaceutical preparations containing the same
DE3667059D1 (en) Benzodipyrroles, processes for their preparation and pharmaceutical compositions containing these compounds
ES8601915A1 (es) Un procedimiento para preparar derivados de piridazinona
ES8609319A1 (es) Procedimiento de preparacion de nuevas fenil-naftiridinas.
ES2000716A6 (es) Un procedimiento para preparar derivados de tetrahidroisoquinoleina
ES8802612A1 (es) Procedimiento para preparar derivados de benzisoselenazolilo
ES2000714A6 (es) Un procedimiento para preparar derivados de tetrahidroisoquinoleina
PT83102B (en) Process for preparing tyrosine pharmaceutical compounds for improvement of the fertility of mammals
ATE38029T1 (de) Benz-trisubstituierte 2-aminotetraline.
ZA829523B (en) New derivatives of bicyclic aminoacids, processes for their preparation, agents containing these compounds and their use, and new bicyclic aminoacids as intermediates and processes for their preparation
IL59968A0 (en) Process for the preparation of nitrogen bridgehead condensed pyrimidine compounds,the salts hydrates and isomers thereof,certain representatives of the compounds prepared and pharmaceutical compositions containing them
IT1197876B (it) Procedimento per la preparazione dell'acido 5,8-diidro-8-etil-5-osso-2-(1-piperazinil)pirido(2,3-d)pirimidin-6-carbossilico
EP0324184A3 (en) 2-amino-1,2,3,4-tetrahydroisoquinoline derivatives, method for their preparation and their use as medicines
IL96796A0 (en) Manufacture of pharmaceutical compositions containing serotonin antagonists
ZA854556B (en) Derivatives of isoxazoloquinolinone,process and intermediates for preparation,use as medicaments,and compositions containing them

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000201