EP4217001A4 - Composition and method for prevention and treatment of cutaneous radiation injury - Google Patents
Composition and method for prevention and treatment of cutaneous radiation injury Download PDFInfo
- Publication number
- EP4217001A4 EP4217001A4 EP21873367.3A EP21873367A EP4217001A4 EP 4217001 A4 EP4217001 A4 EP 4217001A4 EP 21873367 A EP21873367 A EP 21873367A EP 4217001 A4 EP4217001 A4 EP 4217001A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- prevention
- treatment
- composition
- radiation injury
- cutaneous radiation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000019155 Radiation injury Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063081547P | 2020-09-22 | 2020-09-22 | |
US202063081718P | 2020-09-22 | 2020-09-22 | |
PCT/US2021/051583 WO2022066791A1 (en) | 2020-09-22 | 2021-09-22 | Composition and method for prevention and treatment of cutaneous radiation injury |
Publications (2)
Publication Number | Publication Date |
---|---|
EP4217001A1 EP4217001A1 (en) | 2023-08-02 |
EP4217001A4 true EP4217001A4 (en) | 2024-04-24 |
Family
ID=80857195
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP21873367.3A Pending EP4217001A4 (en) | 2020-09-22 | 2021-09-22 | Composition and method for prevention and treatment of cutaneous radiation injury |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP4217001A4 (en) |
JP (1) | JP2023544448A (en) |
AU (1) | AU2021349237A1 (en) |
CA (1) | CA3193398A1 (en) |
IL (1) | IL301530A (en) |
MX (1) | MX2023003357A (en) |
WO (1) | WO2022066791A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2024064898A2 (en) * | 2022-09-22 | 2024-03-28 | Rythera Therapeutics Inc. | Composition and method for prevention and treatment of cutaneous radiation injury |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19621038A1 (en) * | 1996-05-24 | 1997-11-27 | Boehringer Ingelheim Kg | Aminoguanidines, processes for their preparation and medicaments containing these compounds |
US7250445B1 (en) * | 2005-01-14 | 2007-07-31 | Ehrenpreis Eli D | Anti-oxidant suppository for treating radiation proctopathy and other anorectal disorders |
CN101605763B (en) * | 2006-12-21 | 2016-03-09 | 彼得·麦卡勒姆癌症研究所 | Radioprotector compounds and methods involving |
WO2009051628A2 (en) * | 2007-09-06 | 2009-04-23 | Arezou Petrie | Transdermal treatment device and method |
US9616006B2 (en) * | 2007-10-10 | 2017-04-11 | DermaMedics, LLC | Methods and compositions for treating dermatological diseases and conditions |
US20150353912A1 (en) * | 2012-05-31 | 2015-12-10 | Children's Hospital Medical Center | Methods for treating and preventing radiation injury using activated protein c polypeptides |
WO2016142341A1 (en) * | 2015-03-06 | 2016-09-15 | Repoceuticals Aps | Melatonin for preventing and treating radiation vaginitis and proctitis |
-
2021
- 2021-09-22 IL IL301530A patent/IL301530A/en unknown
- 2021-09-22 JP JP2023542836A patent/JP2023544448A/en active Pending
- 2021-09-22 WO PCT/US2021/051583 patent/WO2022066791A1/en unknown
- 2021-09-22 MX MX2023003357A patent/MX2023003357A/en unknown
- 2021-09-22 AU AU2021349237A patent/AU2021349237A1/en active Pending
- 2021-09-22 CA CA3193398A patent/CA3193398A1/en active Pending
- 2021-09-22 EP EP21873367.3A patent/EP4217001A4/en active Pending
Non-Patent Citations (6)
Title |
---|
"Doxepin rinse for oral mucositis", DENTAL ABSTRACTS, MOSBY, ST. LOUIS, MO, US, vol. 54, no. 1, 1 January 2009 (2009-01-01), pages 54 - 55, XP025891715, ISSN: 0011-8486, [retrieved on 20090127], DOI: 10.1016/J.DENABS.2008.08.049 * |
BERGER BERNHARD ET AL: "Severe skin reaction secondary to concomitant radiotherapy plus cetuximab", RADIATION ONCOLOGY, BIOMED CENTRAL LTD, LO, vol. 3, no. 1, 28 January 2008 (2008-01-28), pages 5, XP021039595, ISSN: 1748-717X * |
KAWASHITA YUMIKO ET AL: "Oral management strategies for radiotherapy of head and neck cancer", JAPANESE DENTAL SCIENCE REVIEW, ELSEVIER, AMSTERDAM, NL, vol. 56, no. 1, 20 February 2020 (2020-02-20), pages 62 - 67, XP086387121, ISSN: 1882-7616, [retrieved on 20200220], DOI: 10.1016/J.JDSR.2020.02.001 * |
LALEH SHARIATI ET AL: "Protective effects of doxepin cream on radiation dermatitis in breast cancer: A single arm double-blind randomized clinical trial", BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, BLACKWELL SCIENTIFIC PUBL, GB, vol. 86, no. 9, 25 February 2020 (2020-02-25), pages 1875 - 1881, XP071603255, ISSN: 0306-5251, DOI: 10.1111/BCP.14238 * |
LEE JEFFREY K ET AL: "ASGE guideline on the role of endoscopy for bleeding from chronic radiation proctopathy", GASTROINTESTINAL ENDOSCOPY, ELSEVIER, NL, vol. 90, no. 2, 22 June 2019 (2019-06-22), pages 171, XP085743421, ISSN: 0016-5107, [retrieved on 20190622], DOI: 10.1016/J.GIE.2019.04.234 * |
See also references of WO2022066791A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO2022066791A1 (en) | 2022-03-31 |
IL301530A (en) | 2023-05-01 |
EP4217001A1 (en) | 2023-08-02 |
JP2023544448A (en) | 2023-10-23 |
AU2021349237A1 (en) | 2023-06-08 |
CA3193398A1 (en) | 2022-03-31 |
MX2023003357A (en) | 2023-06-30 |
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Legal Events
Date | Code | Title | Description |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
17P | Request for examination filed |
Effective date: 20230420 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R079 Free format text: PREVIOUS MAIN CLASS: A61K0041000000 Ipc: A61K0031135000 |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20240326 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 45/06 20060101ALI20240320BHEP Ipc: A61K 9/02 20060101ALI20240320BHEP Ipc: A61K 9/00 20060101ALI20240320BHEP Ipc: A61P 43/00 20060101ALI20240320BHEP Ipc: A61P 17/02 20060101ALI20240320BHEP Ipc: A61K 41/00 20200101ALI20240320BHEP Ipc: A61K 31/135 20060101AFI20240320BHEP |