EP4185288A4 - Therapeutic agents and uses thereof - Google Patents
Therapeutic agents and uses thereofInfo
- Publication number
- EP4185288A4 EP4185288A4 EP20946050.0A EP20946050A EP4185288A4 EP 4185288 A4 EP4185288 A4 EP 4185288A4 EP 20946050 A EP20946050 A EP 20946050A EP 4185288 A4 EP4185288 A4 EP 4185288A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- therapeutic agents
- therapeutic
- agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2020/042933 WO2022019892A1 (en) | 2020-07-21 | 2020-07-21 | Therapeutic agents and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP4185288A1 EP4185288A1 (en) | 2023-05-31 |
| EP4185288A4 true EP4185288A4 (en) | 2024-04-24 |
Family
ID=79729760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP20946050.0A Pending EP4185288A4 (en) | 2020-07-21 | 2020-07-21 | Therapeutic agents and uses thereof |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP4185288A4 (en) |
| CN (1) | CN115916195A (en) |
| WO (1) | WO2022019892A1 (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101367802A (en) * | 2008-09-27 | 2009-02-18 | 暨南大学 | Beta-kabarin alkaloids in quassia wood, preparation method and application thereof |
| WO2009047298A2 (en) * | 2007-10-12 | 2009-04-16 | Bioalliance Pharma | Dimers of harmol or of its derivatives and uses thereof |
| WO2021026016A1 (en) * | 2019-08-05 | 2021-02-11 | Ankh Life Sciences Limited | Fused polycyclic dimers |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4631323A (en) * | 1985-07-29 | 1986-12-23 | Honeywell Inc. | Method of making conducting polymer complexes of N-substituted carbazoles and substituted benzaldehydes |
| US7067653B2 (en) * | 2000-05-09 | 2006-06-27 | The Regents Of The University Of California | Porphyrin Based neuton capture agents for cancer therapy |
| US9907786B2 (en) * | 2014-10-21 | 2018-03-06 | Ions Pharmaceutical S.À R.L. | Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof |
-
2020
- 2020-07-21 WO PCT/US2020/042933 patent/WO2022019892A1/en unknown
- 2020-07-21 CN CN202080102648.3A patent/CN115916195A/en active Pending
- 2020-07-21 EP EP20946050.0A patent/EP4185288A4/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009047298A2 (en) * | 2007-10-12 | 2009-04-16 | Bioalliance Pharma | Dimers of harmol or of its derivatives and uses thereof |
| CN101367802A (en) * | 2008-09-27 | 2009-02-18 | 暨南大学 | Beta-kabarin alkaloids in quassia wood, preparation method and application thereof |
| WO2021026016A1 (en) * | 2019-08-05 | 2021-02-11 | Ankh Life Sciences Limited | Fused polycyclic dimers |
Non-Patent Citations (3)
| Title |
|---|
| CHEN XIAOFEI ET AL: "Design, Synthesis, and Biological Evaluation of Novel N-Acylhydrazone Bond Linked Heterobivalent [beta]-Carbolines as Potential Anticancer Agents", MOLECULES, vol. 24, no. 16, 1 August 2019 (2019-08-01), DE, pages 2950, XP055901185, ISSN: 1433-1373, DOI: 10.3390/molecules24162950 * |
| GUO LIANG ET AL: "Synthesis and biological evaluation of novel N 9 -heterobivalent [beta]-carbolines as angiogenesis inhibitors", JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 34, no. 1, 1 January 2019 (2019-01-01), GB, pages 375 - 387, XP093007443, ISSN: 1475-6366, DOI: 10.1080/14756366.2018.1497619 * |
| See also references of WO2022019892A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4185288A1 (en) | 2023-05-31 |
| CN115916195A (en) | 2023-04-04 |
| WO2022019892A1 (en) | 2022-01-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
| 17P | Request for examination filed |
Effective date: 20221208 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
| DAV | Request for validation of the european patent (deleted) | ||
| DAX | Request for extension of the european patent (deleted) | ||
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20240327 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07D 471/12 20060101ALI20240321BHEP Ipc: A61K 31/11 20060101ALI20240321BHEP Ipc: A61K 31/437 20060101AFI20240321BHEP |