Classifications

• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
  • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
  • B65B1/00—Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
  • B65B1/30—Devices or methods for controlling or determining the quantity or quality or the material fed or filled
  • B65B1/36—Devices or methods for controlling or determining the quantity or quality or the material fed or filled by volumetric devices or methods
  • B65B1/363—Devices or methods for controlling or determining the quantity or quality or the material fed or filled by volumetric devices or methods with measuring pockets moving in an endless path
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
  • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
  • B65B1/00—Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
  • B65B1/04—Methods of, or means for, filling the material into the containers or receptacles
  • B65B1/16—Methods of, or means for, filling the material into the containers or receptacles by pneumatic means, e.g. by suction
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
  • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
  • B65B1/00—Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
  • B65B1/30—Devices or methods for controlling or determining the quantity or quality or the material fed or filled
  • B65B1/36—Devices or methods for controlling or determining the quantity or quality or the material fed or filled by volumetric devices or methods
  • B65B1/38—Devices or methods for controlling or determining the quantity or quality or the material fed or filled by volumetric devices or methods by pistons co-operating with measuring chambers
  • B65B1/385—Devices or methods for controlling or determining the quantity or quality or the material fed or filled by volumetric devices or methods by pistons co-operating with measuring chambers moving in an endless path
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
  • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
  • B65B59/00—Arrangements to enable machines to handle articles of different sizes, to produce packages of different sizes, to vary the contents of packages, to handle different types of packaging material, or to give access for cleaning or maintenance purposes
  • B65B59/005—Adjustable conveying means

Definitions

• the present invention relates to an apparatus for filling containers with a powdered material.
• a known type of apparatuses comprises a collecting station at which the containers to be filled are transported and a filling station comprising dispensing means.
• a capping station is arranged downstream of the filling station, provided with a device for capping the containers, and a possible crimp capping station following the capping station.
• the containers are moved from one operating station to the next station by handling assemblies, for example by robotic arms.
• EP 2 280 873 describes an apparatus of this type.
• a further example of this type of apparatus is illustrated in the patent EP 3 307 629.
• the patent describes an apparatus comprising a filling station and a crimp capping station, arranged downstream of the filling station and separated from this station by a separating partition arranged to prevent that the contaminants penetrate into the filling station.
• the containers arranged in respective seats shaped by a nest, which is inserted in a transport receptacle, are transported to the filling station.
• the filling station is provided with a first handling assembly, arranged to extract one container at a time from the nest, transport it to a dispenser to carry out the filling and, then, transport it to a transfer device.
• Means for delivering air are also associated with the filling station to create a pressure higher than the atmospheric pressure and thus avoid any contamination.
• a further handling assembly is arranged beyond the separating partition to collect a container from the transfer device and to guide it to the crimp capping station and then place it, once the crimp capping has been carried out, inside a further nest.
• powdered materials difficult to process are, for example, hygroscopic powders, having a melting temperature close to room temperature which generates significant adhesiveness problems if processed in environmental conditions above 15° C and/or with relative humidity higher than 25%.
• the object of the present invention is that of solving the aforementioned problems, devising an apparatus that allows the effective filling of containers with a powdered material.
• a further object of the present invention is to devise an apparatus which allows a precise measure of the powdered material, in particular in the case of use of a powdered material which has chemical and/or physical characteristics which make it difficult to work.
• a further object of the present invention is to provide an apparatus for filling containers with a powdered material that is versatile and configurable according to the properties of the material to be treated.
• a further object is to provide an apparatus which maximizes the consumption of the powdered material.
• a still further object is to provide an apparatus which guarantees to keep the sterility of the process in an optimal way.
• Another object of the invention is to provide an apparatus that is capable of handling containers in safe and reliable way.
• Still another object is to provide an apparatus which allows the number of discarded containers to be reduced to a minimum at each production cycle.
• Another object is to provide an apparatus of simple constructive and functional conception, provided with reliable operation, versatile use, and relatively unexpensive cost.
• the apparatus for filling containers with a powdered material includes a container feeding station; a filling station, arranged downstream of said feeding station, comprising a measuring assembly configured to fill each said container with a measured quantity of a powdered material, said measuring assembly comprising at least one pair of measuring members, each said measuring member being capable of alternatively collecting a measured quantity of said powdered material and expelling said measured quantity of said powdered material into a relative container, each measuring member defining inside it a calibration chamber.
• the apparatus also comprises a pneumatic circuit which connects each said measuring member to a source of positive pressure and to a source of negative pressure respectively to introduce a flow of a fluid inside said calibration chamber and to create a vacuum condition in said calibration chamber, said pneumatic circuit being configured to regulate the pressure value in each said measuring member independently.
• said pneumatic circuit comprises, for each measuring member, relative conduction means which individually connects each said measuring member to said source of positive pressure and to said source of negative pressure to set the desired pressure value in each measuring member, regardless of the pressure value in the other measuring members.
• said pneumatic circuit comprises at least one pair of diverter valves connected to relative said measuring members, each said diverter valve receiving a flow of a pressurized fluid at inlet thereof and also being connected to said source of negative pressure, each said diverter valve being controlled to selectively enable the passage of said fluid or to enable the creation of a vacuum condition in said calibration chamber of the relative measuring device.
• said conduction means comprises, for each measuring member, a conduit capable of transporting a fluid under pressure to the inlet of said corresponding diverter valve and a further conduit, connected at the inlet to said corresponding diverter valve, suitable to allow connection with said source of negative pressure.
• said pneumatic circuit comprises, for each pair of measuring members, at least one pair of pressure regulators, connected to at least one said positive pressure source.
• said pressure regulators are arranged upstream of said diverter valves.
• each said pressure regulator is connected to a relative conduction means which gives rise to a pair of branches capable of transporting a flow of a compressed fluid to respective measuring members arranged to operate, at a predetermined instant of time, in different operating steps.
• This configuration of the pneumatic circuit is optimized since the connection of each pressure regulator with measuring members which are in different operating phases is exploited.
• the flow of a compressed fluid transported by said branches of the circuit connected to said pressure regulators is used for cleaning said measuring member or for expelling a measured amount of powdered material.
• each said pair of branches is arranged downstream of said relative pressure regulator and upstream of said diverter valves.
• one said pair of branches connected to a relative pressure regulator is fed with a flow of a fluid for cleaning said metering members and the other said pair of branches, connected to the a further pressure regulator is fed with a flow of a fluid for expelling the powder material from said measuring members.
• said apparatus comprises a control panel enabling an operator to carry out the regulation of said pneumatic circuit.
• each measuring member comprises a casing having an open end and a piston, housed inside said casing, said piston comprising a filter, said filter being associated with a head of said piston.
• said calibration chamber is defined between an internal wall of said casing and said head of said piston, at said open end.
• said piston of each measuring member can be operated in translation, upon actuation of a relative actuator member, along a longitudinal direction of said casing, to expel a measured quantity of powdered material in a relative container, and/or said diverter valve associated with said measuring member is controlled to introduce into said calibration chamber a flow of a fluid for expelling said powdered material.
• each said measuring member exerts a compressive force on a layer of said powdered material, which is compacted in said calibration chamber, and/or a vacuum condition is created in said calibration chamber.
• the apparatus minimizes the impact that the powdered materials difficult to process can have in the phases of collecting the powdered material and filling the containers, ensuring a stability of such processes.
• said filling station comprises a feeding receptacle, adapted to contain a predetermined quantity of said powdered material, arranged adjacent to said measuring assembly.
• said feeding receptacle is rotating about a substantially vertical axis of rotation.
• said measuring assembly comprises a support device bearing said at least one pair of measuring members.
• said support device comprises a pair of arms, each carrying at least one measuring member.
• said arms are integral with a stem.
• each said arm bears a pair of measuring members.
• said support device is rotated to bring said measuring members alternately at said feeding receptacle, for collecting the powdered material, and in a position above said containers to fill said containers.
• said stem of said support device is rotated about a rotation axis by a motor member for moving said arms.
• said arms are arranged at diametrically opposite ends of said stem.
• said measuring members borne by respective said arms, at opposite ends of said stem are connected to respective said branches shaped by each said conduction means relative to each said pressure regulator.
• said feeding receptacle comprises a containment body capable of containing said predetermined quantity of said powdered material.
• said containment body can be rotated around said substantially vertical axis of rotation.
• said feeding receptacle comprises at least one collection cavity, made on a wall of said containment body, capable of functioning as a collection tank for said powdered material, in a phase of recovery of said powdered material.
• the provision of at least one collection cavity for the powdered material has the effect of maximizing the consumption of the powdered material, with a consequent reduction of production cost.
• the cavity of collection of material in fact allows the recover inside it of at least a part of the powdered material which remains in the containment body of the feeding receptacle when the material of the batch runs out.
• said containment body comprises a bottom wall and a perimeter wall, which extends from said bottom wall, said at least one collection cavity being made on said bottom wall.
• said collection cavity extends in a direction substantially orthogonal to said bottom wall.
• said at least one collection cavity has a slotted plan shape.
• said feeding receptacle is associated with a first rotation shaft, capable of being rotated around said substantially vertical axis of rotation by a second motor member.
• said containment body is movable in translation, upon actuation of a third motor member, along a direction parallel to said substantially vertical axis of rotation, in a phase of recovery of said powdered material.
• said feeding receptacle comprises a lid arranged above said containment body, said lid having at least one opening for inserting said measuring members in said containment body.
• said lid is movable according to a translation motion, on actuation of a motor member, along a direction parallel to said substantially vertical axis of rotation, in the opposite direction with respect to the translation motion of said containment body.
• said apparatus comprises optical sensor means configured to detect the thickness of the layer of powdered material contained within said containment body.
• said optical sensor means comprise at least one optical fiber.
• said optical sensor means are adapted to send a signal to a control unit when the level of said detected powdered material is lower than said predetermined value.
• said control unit is configured to command, upon receipt of said signal by said optical sensor means, the rotation of said containment body around said substantially vertical axis of rotation by a rotation angle of a value such that said measuring members are aligned to said at least one collection cavity.
• control unit is also configured to control, upon receipt of said signal, the translation of said containment body and of said lid along said direction parallel to said rotation axis in respectively opposite directions.
• said apparatus comprises a first handling assembly which can be moved to transport said at least one container from said feeding station to said filling station.
• said apparatus comprises a capping station, arranged downstream of said filling station.
• said apparatus comprises a second handling assembly which can be moved to transport said at least one container from said filling station to said capping station and to transport each said container from said capping station to a following station.
• said apparatus comprises a crimp capping station arranged downstream of said capping station.
• said crimp capping station is separated from said capping station by a partition wall.
• said apparatus comprises a third handling assembly.
• said third handling assembly may be moved for transporting said at least one container towards said crimp capping station.
• each said handling assembly is made by a robotic arm.
• the use of robotic arms for moving the containers allows an efficient transport of the containers and also allows a better level of cleanliness at the end of the process than the use of handling systems such as, for example, belts, augers, etc.
• said apparatus comprises an insulator that delimits an internal region in which said feeding station, said filling station, said capping station and said crimp capping station are arranged so as to prevent mutual contamination between the external environment and said internal region.
• said insulator is associated with an assembly of control of the characteristics of the internal region delimited by the insulator.
• said control assembly comprises a series of filters, designed to filter the air taken from the region, and a series of fans that introduce a laminar flow of filtered air into the region that allows an environmental control necessary to carry out an aseptic process.
• said laminar flow flows in a vertical direction.
• Figure 1 shows a top view of the apparatus object of the invention
• Figure 2 shows a perspective view of a detail of the apparatus object of the invention
• Figure 3 shows a front view of the detail illustrated in figure 2;
• Figure 4 shows a longitudinal section view of the detail illustrated in Figure 3 along the plane of line IV-IV;
• Figure 5 shows a plan view of the detail illustrated in Figures 2-4;
• Figure 6 shows a perspective view of a further detail of the apparatus
• Figure 7 shows a plan view of the detail illustrated in Figure 6;
• Figure 8 shows a sectional view of the detail illustrated in Figures 6 and 7 along the plane of line VIII-VIII;
• Figure 9 shows a diagram of a pneumatic circuit for pressurizing and depressurizing the seal of a robotic arm used in the apparatus
• Figure 10 shows a schematic representation of a pneumatic circuit relating to a pair of measuring members of the apparatus. Best mode
• the reference number 1 indicates as a whole the apparatus for filling containers with a powdered material and for closing containers according to the present invention.
• the containers 2 can be bottles, vials and the like, intended, for example, for the pharmaceutical, biotechnological or chemical sector.
• the powdered material is a material having physical and chemical characteristics which make it difficult to process. More specifically, the term hardly workable powdered material means a powder that has characteristics such as not to be easily manageable in order to obtain a high precision in the measure.
• powders that are difficult to process are, for example, highly hygroscopic powders, having a melting temperature close to room temperature which generates marked adhesiveness problems if processed at environmental conditions above 15°C and/or with relative humidity higher than 25%.
• An example of a powdered material is the monohydrate form of Cyclophosphamide, which has a melting temperature in the range of 40-45°C, but which can already degrade at temperatures above 30°C. Chemical degradation causes a change in the physical characteristics that prejudice the workability in the measuring process.
• the apparatus 1 includes a frame that defines the supporting structure of the apparatus.
• the frame 3 supports a substantially horizontal work surface 4 on which a series of operating stations are arranged, as described below.
• the frame 3 is associated with an insulator that surrounds the work surface 4 in order to isolate the operating stations from the external environment and thus avoid contamination between the external environment and the internal region delimited by the insulator.
• the insulator also performs the function of ensuring the safety of operators, in particular in the event that cytotoxic powdered materials are treated.
• the insulator has a box-like shape and is fixed to a part of the frame 3 arranged, in a mounting configuration, at the top so as to enclose the operating stations inside.
• the insulator will not be further described as it is known per se.
• the insulator is associated with a control assembly of the characteristics of the internal region delimited by the insulator, which is designed, in particular, to control the level of purity of the air in that region.
• the control assembly includes a series of filters, adapted to filter the air taken from the region, and a series of fans that introduce a laminar flow of filtered air into the region. Laminar flow flows in a vertical direction. The vertical and laminar air flow allows an environmental control that is necessary for carrying out an aseptic process.
• the frame 3 forms a base, not visible in the figures, suitable for housing the motorization systems of the apparatus. Sealing means, not shown, are arranged at a passage area between the base and the region above the work surface 4, for preventing mutual contamination between the two regions.
• the frame 3 is preferably made of stainless steel and covered with stainless steel panels to allow easy sterilization.
• the apparatus 1 comprises a feeding station 5 designed to receive a plurality of containers 2 and transfer them to a collecting area 6.
• the feeding station 5 comprises a transfer member 7 which is made up of a table revolving around a substantially vertical axis of rotation.
• the transfer member 7 can have a discoidal shape.
• the transfer member 7 receives the containers 2 from a transport member, such as, for example, a conveyor belt, not visible in the figures, and is rotated around the axis of rotation to lead the containers 2 towards the collection area 6.
• the transport member is placed inside a sterilization tunnel to ensure the sterility of the containers 2.
• the transfer member 7 is provided with guide means 8 which convey the containers 2 towards the collection area 6.
• guide means 8 which convey the containers 2 towards the collection area 6.
• the containers 2 arriving at the collection area 6 are arranged aligned.
• the apparatus 1 also comprises a first handling assembly 9 adapted to move the containers 2 from the feeding station 5 to a following filling station 10, arranged downstream of the feeding station 5.
• a capping station 11 is arranged downstream of the filling station 10.
• a second handling assembly 9 transports the containers 2 from the filling station 10 to the capping station 11.
• Each handling assembly 9 is made by a robotic arm, more specifically by an anthropomorphic robot.
• Each robotic arm 9 is isolated from the base by sealing means and comprises, in a known way, a base associated with a series of segments connected by joints.
• Gripping means 12 are connected to an end opposite the base, which is the wrist of the robotic arm.
• the gripping means 12 comprise at least one gripper member which is movable alternately, upon activation of an actuator, between a gripping configuration and a release configuration of a container 2.
• the actuator is of the pneumatic type.
• the gripping means 12 comprise a pair of gripper members which are operated by respective actuators to grasp and release the corresponding containers 2.
• Each gripper member comprises an operating portion consisting of two clamping elements which are placed close to each other in the gripping configuration, and spaced apart in the release configuration.
• the operating portion is associated with the wrist of the robotic arm 9 through a connection portion, also not visible in the figures.
• connection portion is coated with a cover element to prevent any contamination of the gripper member by the powdered material and also to prevent contamination of the powdered material.
• the covering element can be made from a bellows equipped with a tightness control system.
• each gripper member is made of stainless steel or of an antistatic plastic material.
• the gripping means 12 are provided with sensors, not shown, which are capable of detecting whether each gripper member has gripped a relative container.
• a series of nozzles not visible in the figures, which are arranged close to the gripping means 12, above the gripping means 12, are also associated with the robotic arm 9.
• the nozzles are connected to a supply circuit for an inert gas such as, for example, argon or nitrogen, so as to blow the gas into each container 2 before filling the container 2 with a powdered material and after filling the container 2.
• an inert gas such as, for example, argon or nitrogen
• the joints of the robotic arm 9 are equipped with pressurized seals. More specifically, the apparatus includes a pneumatic circuit 50 to pressurize and depressurize the seals of each robotic arm 9.
• Figure 9 shows a diagram of the pneumatic circuit 50 for pressurizing and depressurizing a seal of a robotic arm 9.
• the circuit 50 allows setting the pressure of a fluid in the seal of the robotic arm 9 at a value within a range selected by the operator and, in general, allows checking the state of the seal.
• the circuit 50 comprises a proportional pressure regulating valve 51 connected, through a first conduction means 52, to a respective seal of the robotic arm 9.
• the proportional pressure regulating valve 51 is capable of setting the pressure of a fluid entering the seal.
• the fluid is compressed air.
• the proportional pressure regulating valve 51 is connected to a safety valve 53.
• This safety valve 53 allows the inlet pressure of the valve 51 to be kept below a maximum limit value.
• the maximum limit value is the maximum pressure value accepted at the inlet by the proportional pressure control valve 51.
• the safety valve 53 receives incoming compressed air at a pressure P1 and is piloted by a pressure P0.
• P0 means the pressure of the compressed air which is conducted by a source of compressed air 54 entering the circuit 50 while P1 is the pressure outgoing a pressure regulator 55 placed upstream of the safety valve 53.
• the pressure P0 is 6-8 bar while the pressure P1 is a value lower than P0.
• the pressure P1 has a value lower than said maximum limit value of the incoming pressure of the proportional pressure regulating valve 51.
• a second conduction means 56 of compressed air connected to the compressed air source 54, gives rise to two branches: a first branch 56a enters the pressure regulator 55 while a second branch 56b, to which corresponds the pressure P0, is a pilot signal for the safety valve 53.
• the circuit 50 also includes a control valve 57 which has the incoming compressed air, which outgoes from the relative seal of a robotic arm 9 and is connected, when outgoing, to a pressure sensor 58 and to a silencer 59. Control valve 57 is piloted by pressure P0.
• the pressure sensor 58 detects the pressure value in the seal and sends an alarm signal to the control unit if the measured value is outside the pressure range set by the operator. In the event that it is necessary to perform maintenance on the seal, it can be depressurized by means of the control valve 57, by switching the control valve 57 and discharging all the pressurized air in the seal. In addition, any pressure loss or overpressure in the seal can be detected by reading the pressure sensor 58.
• the containers 2 are transported by the first robotic arm 9 from the collection area 6 to the filling station 10 and are released resting on a support member of the type of a plate, not visible in the figures.
• a weighing assembly 13 is arranged at the filling station 10, comprising at least one load cell for measuring the tare weight of a container 2, before filling it with a powdered material, and the gross weight of the container 2 once filling with a powdered material has been carried out.
• the apparatus is equipped with a control unit capable of managing the entire process and, in particular, allowing identification of the containers 2 to be discarded based on the net weight determined starting from the acquired data of gross and tare weight.
• the weighing assembly 13 comprises a pair of load cells and a compensation cell designed to detect any inconvenience during the weighing step, such as vibrations, and to eliminate such disturbances.
• the weighing assembly 13 is supported by a support 14 integral with the base of the apparatus.
• the filling station 10 comprises a measuring assembly 15.
• the measuring assembly 15 comprises a support device 16 bearing at least one pair of measuring members 17, wherein each measuring member 17 is adapted to alternatively take a measured quantity of powdered material and dispense the measured quantity of powdered material in a suitable container 2.
• Each measuring member 17 is adapted to collect a measured quantity of material from a feeding receptacle 18, arranged next to the measuring assembly 15, which is described below.
• the support device 16 comprises a pair of arms 19, each arm forming at least one seat 20 for a respective measuring member 17.
• each arm 19 supports a pair of measuring members 17 and, therefore, forms a pair of seats 20 for respective measuring members 17.
• the arms 19 are connected integrally to a stem 21 and are mounted on the stem 21 so as to occupy positions at the opposite ends of the diameter of the stem 21.
• the rod 21 is rotated according to a rotation axis A by a first motor member 22. More specifically, the stem 21 is rotated according to an alternating motion so as to bring the measuring members 17 of each arm 19 alternately at the feeding receptacle 18, to collect the powder material, and in an overlying position the containers 2 for filling.
• the configuration of the support device 16 allows, upon actuation of the first motor member 22, at the same time the collection of the powdered material by means of the measuring members 17 carried by an arm 19 and the filling of the containers 2 by means of the measuring members 17 carried by the opposite arm 19.
• the stem 21 is rotated at a predetermined angle of rotation around the axis of rotation A.
• the rotation angle is substantially equal to 180°.
• each arm 19 forms a series of support portions aligned along a vertical direction to keep each measuring member 17 stable during the operating steps.
• Each measuring member 17 comprises a calibration chamber that defines the volume of the powdered material to be inserted inside each container 2.
• Each metering member 17 comprises a casing 23 having a tubular shape and a piston, not visible in the figures, which is housed inside the casing 23.
• the casing has an open end and the calibration chamber is defined between an internal wall of the casing and a piston head, at said open end.
• the piston comprises a body, internally hollow, and a head associated with a filter.
• the filter is made from a mesh, preferably made of metal material, which is fixed to an edge of the piston head and forms a surface of the piston head.
• the filter is permeable to the passage of a flow of a fluid and is impermeable to the passage of powdered material.
• the piston head can have a truncated cone shape.
• the piston can be operated in sliding, on activation of an actuator member, along a longitudinal direction to expel the powdered material contained in the calibration chamber or to modify, if necessary, the dimensions of the calibration chamber as well as to carry out the cleaning of the piston. In the latter case, the piston is operated sliding along a longitudinal direction for a stroke that extends outside the casing 23.
• Each metering member 17 is connected, by means of a pneumatic circuit 60, to a source of positive pressure and to a source of negative pressure respectively to introduce a flow of a fluid into the calibration chamber and to create a vacuum condition in the calibration chamber.
• the source of negative pressure can be a vacuum pump.
• the positive pressure source can be a compressor or a source of a compressed inert gas such as, for example, nitrogen or argon.
• a flow of compressed air or an inert gas is used and in the phase of expelling the material, a flow of compressed air or a flow of an inert gas can be used.
• Each measuring member 17 is controlled, by means of the pneumatic circuit 60, independently with respect to the other measuring members 17 in order to be able to autonomously regulate the pressure in each measuring member 17.
• the pneumatic circuit 60 allows a precise regulation of the pressure in each measuring member 17 in order to compensate for any tolerance errors, obtaining a uniform measure for all measuring members 17.
• the pneumatic circuit 60 comprises, for each measuring member 17, a diverter valve 61 which receives incoming pressurized fluid at its inlet and is also connected, through connection means 62, to a vacuum pump 63.
• the diverter valve 61 is controlled to selectively allow the passage of a fluid under pressure or to create a vacuum condition in the calibration chamber of the relative measuring member 17 so as to suck up the powdered material.
• Figure 10 shows a diagram of the pneumatic circuit 60 relating to a pair of measuring members 17a, 17b arranged diametrically opposite on the stem 21 or, better, measuring members 17 which operate, at an instant of time t, in different operating phases.
• Each diverter valve 61 is connected at the outlet to a relative measuring member 17a, 17b by interposing a pair of filters 64.
• the redundancy of the filters 64 guarantees a condition of maximum safety for the operator in the event that it is necessary to replace or to carry out maintenance on one of the filters 64.
• the redundancy of the filters 64 also makes it possible to ensure a high level of sterility of the fluids entering the measuring members 17a, 17b.
• the circuit 60 Upstream of the diverter valves 61, the circuit 60 comprises a fluid distribution block 65 for the cleaning and expulsion phases.
• the distribution block 65 receives incoming compressed air for cleaning and for expelling compressed air or argon or nitrogen.
• the compressed air is transported to the distribution block 65 through relative conduction means connected to a source of compressed air 66.
• Argon and nitrogen are transported to the distribution block 65 respectively by relative conduction means connected respectively to a source of compressed argon 67 and to a source of compressed nitrogen 67'.
• a first conduction means 68 which conveys a flow of compressed air to a pressure regulator 69 is connected at the outlet to the distribution block 65 for each pair of measuring members 17.
• the first conduction means 68 gives rise, downstream of the pressure regulator 69, to two branches 68a, 68b relating to the cleaning steps of respective measuring members 17a, 17b.
• a second conduction means 70 is also connected at the outlet to the distribution block 65 which conveys a flow of compressed air or a flow of a compressed inert gas at the inlet to a further pressure regulator 69 and, downstream of the pressure regulator 69, gives rise to a pair of branches 70a, 70b relating to the ejection phases of respective measuring members 17a, 17b.
• each pressure regulator 69 the relative conduction means 68, 70 gives rise to two branches connected to respective measuring members 17a, 17b arranged diametrically opposite on the stem 21 or, better, measuring members 17 which operate, at an instant of time t, in different operational phases.
• the dispenser 17a is in the phase of expulsion of the powdered material
• the opposite dispenser 17b is in the suction phase of material, therefore, it is connected to the vacuum pump or vice versa.
• the configuration of the circuit 60 is optimized by exploiting the connection of each pressure regulator 69 to the measuring members 17 which operate, at a predetermined instant t, in different operating phases.
• the circuit 60 associates to each measuring member 17, for example for the measuring device indicated with 17a, the branch 68a of the first conduction means 68, which passes a compressed fluid for cleaning, and the branch 70a of the second conduction means 70 which passes a fluid in order to expel the powdered material.
• the branches 68a, 70a cross and a third conduction means 71 connected to the diverter valve 61 is connected to the node of the branches.
• Non-return valves 72 are arranged on each branch 68a, 70a to prevent the passage of fluids from one branch to the other and to prevent the creation of overpressure on the valves.
• the circuit 60 associates the branch 68b of the first conduction means 68, which passes a fluid for cleaning, and the branch 70b of the second conduction means 70, which passes a fluid for expelling the powdered material.
• the branches 68b, 70b cross and a third conduction means 73 connected to the diverter valve 61 is connected to the node of the branches.
• the non-return valves 72 prevent the passage of fluids from one branch to the other.
• the pneumatic circuit 60 and the pneumatic circuit 50 for pressurizing the seals of the robotic arms 9 are controlled by means of a control panel which allows the modifications, for example the regulation operations, to be carried out, improving control over the circuits.
• Each measuring member 17 is fed independently from the pneumatic circuit 60 described above with a flow of a fluid under pressure to expel the collected powdered material or is connected to the vacuum pump to create a vacuum condition in the calibration camera.
• each measuring member 17 can expel the powdered material by the force exerted by the piston when it is operated in translation inside the casing 23.
• a vacuum condition can be created in the calibration chamber of each measuring member 17 and/or the powdered material is collected by applying a compression force of the measuring device 17 on the material compacting in the calibration chamber.
• a ring-shaped member 24 for cleaning the measuring members 17 is mounted around the stem 21.
• the cleaning member 24 has a series of openings provided with suction means, not visible in the figures, at which each measuring member 17 can be inserted to remove the residual material that has remained adhered.
• the cleaning member 24 is equipped with a scraper element, not shown, arranged to cooperate with the suction means in removing the material.
• the feeding receptacle 18 is arranged adjacent to the support device 16 of the measuring members 17 and is mounted on a base 25 integral with a first shaft 26, capable of being rotated around a substantially vertical axis of rotation B by a second member motor 27.
• the second motor member 27 transmits the rotation motion to the shaft 26 by means of transmission 28.
• the shaft 26 is also connected to a third motor member 29 which drives it in translation along a longitudinal direction parallel to the axis of rotation B thanks to the interposition of screw means 30, for example a ball screw.
• the feeding receptacle 18 comprises a containment body 31 adapted to contain a predetermined quantity of a powdered material.
• the containment body 31 is revolving around the axis of rotation B upon actuation of the second motor member 27 and is operated in translation upon actuation of the third motor member 29.
• the containment body 31 is rotated by an angle of rotation whose value is varied periodically to enable the measuring members 17 to collect the material from different regions of the layer of material contained within the containment body 31.
• the containment body 31 comprises a bottom wall 33 from which a perimeter wall 34 develops.
• the containment body 31 has a cylindrical shape.
• At least one collection cavity 35 is on the bottom wall 33, which functions as a collection tank for the powdered material when the level of the material inside the containment body 31 is lower than a predetermined reference value.
• the collection cavity 35 is open on one side facing the inside of the containment body 31 to allow the entry of powdered material.
• the collection cavity 35 extends along a direction orthogonal to the bottom wall 33, in the thickness of the base 25.
• the collection cavity 35 has a slotted plan shape.
• the feeding receptacle 18 comprises a pair of collection cavities 35.
• Optical sensor means configured to measure the thickness of the layer of powdered material inside the containment body 31 are associated with the feeding receptacle 18.
• the optical sensor means may comprise an optical fiber.
• the lid 32 forms an opening 36, for example in the shape of a slot, which allows the measuring members 17 to be inserted into the containment body 31 for collecting the powdered material.
• a conveying element 37 having a tubular shape, which is connected to a container for discharging the powdered material, not visible, for discharging the powdered material into the containment body 31 when it is necessary to restore the layer of the material.
• the unloading container preferably uses the force of gravity to unload the material into the conveying element 37.
• the lid 32 is integral with a second shaft 38 which is operable in translation by a motor member. More specifically, in a phase of recovery of the powdered material, the lid 32 is driven in translation along a direction parallel to the axis of rotation B in an opposite direction with respect to the movement of the containment body 31. In this way, the lid 32 maintains a fixed position with respect to the containment body 31, allowing the phase of recovery of the material to be carried out, which is better explained below.
• the second shaft 38 is coaxial with the first shaft 26.
• the feeding receptacle 18 also comprises a collection member connected to the lid 32 which is activated to rake the powdered material towards the collection cavity 35, favoring the recovery of the powder material.
• the collection member performs the function of deaerating and compacting the layer of powdered material before the material is removed by the measuring members 17.
• the collection member has a helical shape.
• the containers 2 are weighed again by the weighing assembly 13 to determine the gross weight of each container 2 and are collected by the second robotic arm 9.
• the second robotic arm 9 transports the containers to the capping station 11 and, once arrived at this station 11, supports the containers by the gripping means 12 for a predetermined time interval necessary for the application of relative caps on the containers 2.
• the capping station 11 comprises a first device 39 for feeding the caps, which is made from a container having a truncated cone shape.
• the first feeding device 39 is vibrating and forms a pair of outlet channels to release, step by step, a pair of caps to be applied on relative containers 2.
• a first pre-feeding device 40 consisting of a hopper containing a predetermined quantity of caps can be associated with the first feeding device 39.
• the pre-feeding device 40 is equipped with an unloading element, for example an unloading chute, to supply the caps to the first feeding device 39.
• the first pre-feeding device 40 is arranged near an access point of the insulator to allow easy loading of the caps.
• the capping station 11 also comprises a capping device 41 which collects the outgoing caps from the feeding device 39 and makes them available to the containers 2, preferably one pair of caps one at a time.
• the capping device 41 transports the caps to the containers 2 and positions them aligned with the open end of the containers 2, associating them with the containers 2. In the case of using bottles, the caps are positioned aligned with the orifice of the bottles.
• the second robotic arm 9 can be moved in order to associate the caps with the containers 2 and to complete the capping.
• the second robotic arm 9 carries the capped containers 2 on a release surface 42.
• the release plane 42 is located at a partition wall 43 interposed between the capping station 11 and a following crimp capping station 44.
• the capping station 11 comprises sensors, not shown, configured to detect the presence of the cap on each container 2.
• the sensors may be optical sensors such as, for example, cameras.
• the second robotic arm 9 is moved again towards the capping station 11 to carry out the capping of the container 2 previously detected.
• the handling device 41 collects and make available the missing cp. The further cap collected from the handling device 41 is expelled.
• the crimp capping station 44 comprises a second device 45 for feeding crimp caps having a truncated cone shape.
• the feeding device 45 is vibrating and is equipped with an outlet guide 46 to make the crimp caps available to the containers 2.
• a pre-feeding device 47 consisting of a hopper containing a predetermined quantity of crimp caps can be associated with the feeding device 45, as in the case of the capping station 11.
• the pre-feeding device 47 is equipped with an unloading element, for example an unloading chute, for supplying the crimp caps to the feeding device 45.
• the crimp capping station 44 comprises a third robotic arm 9 for handling the containers 2.
• the characteristics of the first and the second robotic arm 9 are also applicable to the third robotic arm 9 with the exception of the nozzles as the third arm 9 does not supply an inert gas into the containers 2.
• the crimp capping station 44 comprises a crimp capping device 48 comprising support means of containers equipped with closing caps and a series of crimp capping heads each equipped with a crimp capping blade oscillating between a disengagement position and a working position for deforming the crimp cap around the neck of the bottle.
• the crimp capping device 48 is not further described as it is known per se.
• the third robotic arm 9 collects the containers 2 from the release surface 42 and transports them to the crimp capping device 48 by taking the crimp caps off the feeding device 45.
• the crimp capping station 44 comprises sensors, not shown, configured to detect the presence of the crimp cap on each container 2.
• the third robotic arm 9 holds the container 2 equipped with the crimp cap with the gripping means and is moved back towards the feeding device 45 for collecting the crimp cap to be applied to the container 2 with the missing crimp cap. The third robotic arm 9 is then moved towards the crimp capping device 48 for crimp capping the container 2.
• the containers 2 arriving at the feeding station 5 are transferred by the transfer member 7 from the conveyor belt to the release surface 6 and are collected, preferably in pairs, by the first robotic arm 9.
• the first robotic arm 9 transports a pair of containers 2 from the release surface 6 to the filling station 10 and, in particular, releases them to the weighing assembly 13 to measure the tare of the containers 2.
• each container 2 is filled with a measured quantity of a powdered material by means of the measuring assembly 15.
• the discharge of the powdered material can take place by moving the piston of the measuring member 17 and/or by the flow of compressed air or an inert gas introduced into the calibration chamber from the pneumatic circuit 60.
• At least one further measuring member 17 collects a measured amount of powdered material from the feeding receptacle 18.
• the containment body 31 of the feeding receptacle 18 is rotated around the rotation axis B by a rotation angle which is periodically varied to allow the measuring members 17 to take the material from regions different from the layer of material contained in the containment body 31.
• the measuring members 17 carried by the relative arm 19 are inserted through the opening of the lid 32 and each collects a predetermined amount of powdered material, defined by the volume of the calibration chamber.
• the collection takes place through the application of a compression force by the pistons of the pair of measuring members 17 on the layer of the powdered material and/or by suction thanks to the creation of a vacuum condition in the calibration chambers.
• the thickness of the layer of powdered material inside the containment body 31 is kept approximately constant thanks to the feeding of the material by the discharge container.
• the optical sensor means detects that the layer of material inside the containment body 31 is below a predetermined value, due to the exhaustion of the material in the discharge container, it sends a signal to the control unit.
• the control unit commands the implementation of a recovery phase of the remaining powdered material in the containment body 31.
• control unit controls the rotation of the containment body 31 around the axis of rotation B by a rotation angle having a value such as to bring the measuring members 17 aligned with the collection cavity 35 along a longitudinal direction.
• the rotation angle is, for example, 360°.
• the containment body 31 is also operated in translation along a direction parallel to the axis of rotation B, by the action of the third motor member 29, on command of the control unit.
• the lid 32 is in turn translated along the same direction in the opposite direction to that of the containment body 31.
• the measuring members 17, aligned with the collection cavity 35 can collect the powdered material contained in the cavity and, thanks to the translation of the feeding receptacle 18, may recover the material by exploiting the depth of the collection cavity 35.
• the collecting operation, in the recovery phase takes place in the manner described for the steady state operation phase.
• the control unit establishes, based on the net weight values, the suitability of the containers 2.
• the first robotic arm 2 having completed the filling of the containers 2, performs a return stroke to collect a further pair of empty containers 2.
• the second robotic arm 9 transfers the pair of containers 2 below the capping device 41 and keeps them in position, by the gripping means 12, so that respective caps are applied to the containers 2.
• the third robotic arm 9 collects the pair of containers 2 from the release surface 42 and transports them to the crimp capping device 48, taking a pair of crimp caps from the relative feeding device 45 during the path.
• the crimp capping device 48 is operated to apply a capsule on each container 2 and perform the capping of each container 2.
• the apparatus according to the present invention achieves the object of effectively filling the containers with a powdered material thanks to the fact that the pressure of the fluid entering the calibration chamber of each measuring device and, equally, the negative pressure can be adjusted to create the vacuum in the chamber, independently from the other measuring members.
• the independent pressure regulation is useful for solving problems of incorrect measure that can occur due to the characteristics of the material, for example due to the fact that it has a significant adhesiveness.
• An advantageous aspect of the present apparatus is the fact that the piston of each measuring member can be translated inside the relative casing for discharging the powder material, in combination with the insertion of the supplied fluid into the calibration chamber from the pneumatic circuit or as an alternative to the fluid.
• the compression exerted by the measuring member on the layer of the powders material can be combined with the suction due to the vacuum condition created in the calibration chamber.
• the apparatus minimizes the impact that hardly workable powders can have in the phases of collecting the powdered material and filling the containers, ensuring stability to these processes.
• a further advantage offered by the apparatus according to the present invention is to maximize the consumption of the powdered material thanks to the provision of a rotating feeding receptacle equipped with at least one material collection cavity.
• the material collection cavity in fact allows the recovery inside it at least a part of the powdered material which remains in the containment body of the feed receptacle when the material present in the discharge container ends, or when the material of the batch runs out.
• the fact that the measuring members collect the material from the collection cavity, in the recovery phase, has the effect of significantly reducing, for each batch of material used, the quantity of powdered material that is not used for filling the containers. Optimizing the consumption of powdered material leads to a reduction in production costs.
• An aspect to underline is that the use of robotic arms to move the containers achieves an efficient transport of the containers and also allows the minimization of the number of containers rejected at each production cycle. If the sensors present in the capping and crimp capping stations do not respectively detect the presence of a cap or a crimp cap on a container, the control unit commands the movement of the robotic arms in order to recover the cap or crimp cap and apply them again on that container.
• the robotic arms allow the change of their trajectory according to different needs and, therefore, allow the aforementioned recovery functions. This means that it is possible to reduce the number of containers to be rejected.
• the robotic arms for handling the containers make it possible to maintain a level of cleanliness at the end of the process that is better than the use of handling systems such as, for example, belts, augers, etc.
• An advantage is linked to the provision of an insulator that surrounds the operating stations, preventing contamination between the external environment and the operating region, as well as to the provision of a control unit that generates a vertical laminar air flow inside the insulator. These characteristics are relevant in sectors that require precise environmental control during the process, such as, for example, the pharmaceutical sector, to preserve the sterility of the containers and the product, as well as to ensure the safety of operators, especially when using cytotoxic products.
• the configuration of the measuring assembly comprising a support device, which leads the measuring members alternatively to collect the material and to carry out the filling, and, in particular, the fact that the measuring members have a compact configuration and reduced size, minimizes the interaction with the vertical laminar air flow and, therefore, minimizes the occurrence of turbulence phenomena. In this way the measuring assembly helps to ensure that the sterility level of the process is maintained.

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• Engineering & Computer Science (AREA)
• Mechanical Engineering (AREA)
• Quality & Reliability (AREA)
• Basic Packing Technique (AREA)

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• 2020
  • 2020-04-24 IT IT102020000008944A patent/IT202000008944A1/it unknown
• 2021
  • 2021-04-20 WO PCT/IT2021/050118 patent/WO2021214807A1/en unknown
  • 2021-04-20 EP EP21726999.2A patent/EP4139212A1/en active Pending

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