EP3953338A4 - Conjugates and their use as imaging agents - Google Patents
Conjugates and their use as imaging agents Download PDFInfo
- Publication number
- EP3953338A4 EP3953338A4 EP20788472.7A EP20788472A EP3953338A4 EP 3953338 A4 EP3953338 A4 EP 3953338A4 EP 20788472 A EP20788472 A EP 20788472A EP 3953338 A4 EP3953338 A4 EP 3953338A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- conjugates
- imaging agents
- imaging
- agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012216 imaging agent Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/004—Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
- C07D255/02—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/66—Arsenic compounds
- C07F9/70—Organo-arsenic compounds
- C07F9/74—Aromatic compounds
- C07F9/78—Aromatic compounds containing amino groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Radiology & Medical Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2019901277A AU2019901277A0 (en) | 2019-04-12 | Conjugates and their use as imaging agents | |
PCT/AU2020/050359 WO2020206503A1 (en) | 2019-04-12 | 2020-04-09 | Conjugates and their use as imaging agents |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3953338A1 EP3953338A1 (en) | 2022-02-16 |
EP3953338A4 true EP3953338A4 (en) | 2023-06-07 |
Family
ID=72750792
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20788472.7A Pending EP3953338A4 (en) | 2019-04-12 | 2020-04-09 | Conjugates and their use as imaging agents |
Country Status (7)
Country | Link |
---|---|
US (2) | US20220152229A1 (en) |
EP (1) | EP3953338A4 (en) |
JP (1) | JP2022529335A (en) |
CN (1) | CN114206844A (en) |
AU (1) | AU2020256682A1 (en) |
CA (1) | CA3136647A1 (en) |
WO (1) | WO2020206503A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL302033A (en) * | 2020-10-14 | 2023-06-01 | Centenary Inst Of Cancer Medicine And Cell Biology | Therapeutic radiolabelled conjugates and their use in therapy |
WO2023060317A1 (en) * | 2021-10-14 | 2023-04-20 | Centenary Institute Of Cancer Medicine And Cell Biology | Processes for preparing radiolabelled conjugates |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPR874601A0 (en) * | 2001-11-08 | 2001-11-29 | Unisearch Limited | Selective targeting of apoptotic cells |
-
2020
- 2020-04-09 WO PCT/AU2020/050359 patent/WO2020206503A1/en unknown
- 2020-04-09 EP EP20788472.7A patent/EP3953338A4/en active Pending
- 2020-04-09 CA CA3136647A patent/CA3136647A1/en active Pending
- 2020-04-09 AU AU2020256682A patent/AU2020256682A1/en active Pending
- 2020-04-09 JP JP2021560692A patent/JP2022529335A/en active Pending
- 2020-04-09 US US17/594,325 patent/US20220152229A1/en active Pending
- 2020-04-09 CN CN202080044260.2A patent/CN114206844A/en active Pending
-
2023
- 2023-08-18 US US18/452,312 patent/US20240009330A1/en active Pending
Non-Patent Citations (4)
Title |
---|
HO SHON I A ET AL: "Comparison of a novel Hsp90 ligand radiolabelled with Indium-111 and Gallium-67 for imaging of cell death and dosimetry estimations", EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, vol. 39, no. Suppl 2, 1 January 2012 (2012-01-01), pages S215 - S216, XP055870365 * |
R. A. DUMONT ET AL: "Novel 64Cu- and 68Ga-labeled RGD conjugates show improved PET imaging of alpha V beta 3 Integrin expression and facile radiosynthesis", THE JOURNAL OF NUCLEAR MEDICINE, vol. 52, no. 8, 15 July 2011 (2011-07-15), US, pages 1276 - 1284, XP055747640, ISSN: 0161-5505, DOI: 10.2967/jnumed.111.087700 * |
SARKO D. ET AL: "Bifunctional Chelators in the Design and Application of Radiopharmaceuticals for Oncological Diseases", CURRENT MEDICINAL CHEMISTRY, vol. 19, no. 17, 1 May 2012 (2012-05-01), NL, pages 2667 - 2688, XP093040867, ISSN: 0929-8673, DOI: 10.2174/092986712800609751 * |
See also references of WO2020206503A1 * |
Also Published As
Publication number | Publication date |
---|---|
JP2022529335A (en) | 2022-06-21 |
WO2020206503A9 (en) | 2021-05-06 |
US20220152229A1 (en) | 2022-05-19 |
US20240009330A1 (en) | 2024-01-11 |
EP3953338A1 (en) | 2022-02-16 |
AU2020256682A1 (en) | 2021-11-04 |
CN114206844A (en) | 2022-03-18 |
CA3136647A1 (en) | 2020-10-15 |
WO2020206503A1 (en) | 2020-10-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
17P | Request for examination filed |
Effective date: 20211112 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: HO SHON, IVAN Inventor name: HOGG, PHILIP |
|
DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20230508 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07B 59/00 20060101ALI20230428BHEP Ipc: A61K 103/00 20060101ALI20230428BHEP Ipc: A61K 51/08 20060101ALI20230428BHEP Ipc: A61K 51/04 20060101ALI20230428BHEP Ipc: C07F 9/66 20060101ALI20230428BHEP Ipc: A61K 49/10 20060101ALI20230428BHEP Ipc: A61K 49/04 20060101ALI20230428BHEP Ipc: C07D 255/02 20060101AFI20230428BHEP |