EP3952837A1 - Ointment for the treatment of burns - Google Patents

Ointment for the treatment of burns

Info

Publication number
EP3952837A1
EP3952837A1 EP20718759.2A EP20718759A EP3952837A1 EP 3952837 A1 EP3952837 A1 EP 3952837A1 EP 20718759 A EP20718759 A EP 20718759A EP 3952837 A1 EP3952837 A1 EP 3952837A1
Authority
EP
European Patent Office
Prior art keywords
olive oil
burns
oil
treatment
ointment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20718759.2A
Other languages
German (de)
French (fr)
Inventor
Helen PATSIANIDI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP3952837A1 publication Critical patent/EP3952837A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20—Milk; Whey; Colostrum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Definitions

  • the invention relates to an ointment for the treatment of burns and is the product of intense mixing and mild heat treatment of the following ingredients: olive oil, petroleum jelly, goose fat, sulfanilamide powder, rapeseed oil, vitamins A, D and E.
  • This ointment has the advantage of other products which are not therapeutic but preservative.
  • This treatment can mainly heal damaged skin tissues from burns of the first (1st), second (2nd) but also equally and third (3rd) degree and as well as wounds that come from the lesions.
  • the estimated third-degree burn healing beginning is from ten (10) to twenty-one (21) days, with the most common beginning of healing at fourteen (14) days.
  • the use of this ointment reduces healing in half the time compared to other methods and products, but its main feature is that it leaves no scars after healing.
  • the precondition for this to happen, however, is its application from the first day of the burn, as well as how it is applied: a sufficient amount of ointment is applied to a cotton cloth wich is sterile, applied in order to heal to the wound so that no grid (scar tissue) appears on the wound during healing. This also helps protect the wound against exogenous contaminants. Change to this fabric is done every 48 hours, and the sterile fabric is glued to the healthy areas of the skin with paper tape the other way so as to breath the skin.
  • Exemplary other similar techniques are based on patents such as RU2452475C2, CN102349920B, US3761590, which generally refer to the use of sulfanilamide and other active compounds that belong to the group of sulfonamides, such as having sulfadiazine that are antibacterial and antibiotic action, but not in powder form with specific grains, nor in combination with the use of olive oil, petroleum jelly, goose fat, rapeseed oil and vitamins A, D and E.
  • This preparation is in the form of an ointment, resulting from intense mixing and gentle heating, for a period of twenty (20) to thirty (30) minutes, and then stored in a shady and cool place at a temperature of four (4° C) to twenty-five (25 ° C) degrees Celsius and the exact method of preparation is as follows:
  • the mixing of the ingredients takes place in a double-walled container and. at a constant temperature for a period of twenty (20) to thirty (30) first minutes of the hour with a constant mixing rate.
  • a vacuum and pressure mixer or homogenizer mixer or pressure cooker assemblies are designed to provide high quality productions of pharmaceutical preparations and cosmetics, gels, toothpaste, mascara, hair care products etc.
  • the mixing temperature should remain constant throughout the mixing as deviations adversely affect the result and the optimum temperature range is from twenty (20° C) to forty (40° C) degrees Celsius, preferably from twenty-five (25° C) to thirty-five (35° C) degrees Celsius, ideally from twenty-seven (27° C) to thirty-two (32° C) degrees Celsius.
  • the rotational speed during homogenization may be from 2800 rpm to 3100 rpm, preferably from 2850 rpm to 3050 rpm, ideally from 2900 rpm to 3000 rpm.
  • the mixing sequence is as follows: first mix the first (1st) with the second (2nd) and then add the third (3rd) to the resulting mixture and then add the fifth (5th) to the resulting mixture component and then to the resulting mixture is added the fourth component (4th).
  • goose fat should be golden in color without any foreign matter and be homogeneous, with a characteristic odor of goose.
  • the goose fat treatment should be mild and have a maximum treatment temperature of eighty (80° C) degrees Celsius.
  • Sulfanilamide should be fine-grained, if it does not have the necessary granulometry characteristics, the friction component is converted to a finer powder, in particular less than thirty (30mm) microns, preferably less than twenty two (22mm), ideally the granulometry should be from sixteen microns (16mm) to twenty two microns (22mm) .
  • Olive oil is preferably 2-3% low-acid olive oil and even better Virgin Olive Oil, which is virgin olive oil, that is olive oil produced only by natural and mechanical processes, with good organoleptic characteristics, with a free acidity of not more than 2.0%, and even better Extra Virgin Olive Oil, which is virgin olive oil, produced solely by natural and mechanical processes, with a perfect aroma and taste, with a free acidity of not more than 0.8%.
  • the final moisture content of the ointment should be from 10% to 20% by weight, preferably from 12.5% to 17.5% by weight.
  • the above product after being stored in the refrigerator, takes the form of a pale yellow aqueous ointment with a characteristic odor of goose and butter.
  • the above product after its airtight packaging, remains active, in a refrigerator of four (4° C) degrees Celsius and at a temperature of up to twenty-five (25° C) degrees Celsius, in a shady and cool place for twelve (12) months.
  • the preservative used is potassium sorbate from 0.1% to 0.3% by weight, preferably from 0.1% to 0.2% by weight.
  • the ointment is suitable for burns of all three degrees, as defined below based on the depth of the injury. In addition, it is also suitable for healing of other skin lesions such as openings in the skin caused by bedtime.
  • the ointment is suitable for:

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention refers to an ointment for the treatment of burns and skin lesions in general and is the product of intense mixing and mild heat treatment of the following ingredients: olive oil, petroleum jelly, goose fat, sulfanilamide powder, rapeseed oil, vitamins A,D & E. This preparation is in the form of an ointment, resulting from intense mixing and gentle heating, for the first 20-30 minutes. The mixing sequence, the active ingredient granulation, the combination of the active ingredient and the natural ingredients, the use of vitamins and oils, the mild heat treatment have beneficial effects and reduce the healing time. This final product is used for external use-spread on the burn area of the skin resulting its radical as much as possible painless and rapid healing. Its main feature is that there are no visible scars.

Description

DESCRIPTION
Ointment for the treatment of burns
The invention relates to an ointment for the treatment of burns and is the product of intense mixing and mild heat treatment of the following ingredients: olive oil, petroleum jelly, goose fat, sulfanilamide powder, rapeseed oil, vitamins A, D and E.
This ointment has the advantage of other products which are not therapeutic but preservative. This treatment can mainly heal damaged skin tissues from burns of the first (1st), second (2nd) but also equally and third (3rd) degree and as well as wounds that come from the lesions.
The estimated third-degree burn healing beginning is from ten (10) to twenty-one (21) days, with the most common beginning of healing at fourteen (14) days. The use of this ointment reduces healing in half the time compared to other methods and products, but its main feature is that it leaves no scars after healing. The precondition for this to happen, however, is its application from the first day of the burn, as well as how it is applied: a sufficient amount of ointment is applied to a cotton cloth wich is sterile, applied in order to heal to the wound so that no grid (scar tissue) appears on the wound during healing. This also helps protect the wound against exogenous contaminants. Change to this fabric is done every 48 hours, and the sterile fabric is glued to the healthy areas of the skin with paper tape the other way so as to breath the skin.
Exemplary other similar techniques are based on patents such as RU2452475C2, CN102349920B, US3761590, which generally refer to the use of sulfanilamide and other active compounds that belong to the group of sulfonamides, such as having sulfadiazine that are antibacterial and antibiotic action, but not in powder form with specific grains, nor in combination with the use of olive oil, petroleum jelly, goose fat, rapeseed oil and vitamins A, D and E.
This preparation is in the form of an ointment, resulting from intense mixing and gentle heating, for a period of twenty (20) to thirty (30) minutes, and then stored in a shady and cool place at a temperature of four (4° C) to twenty-five (25 ° C) degrees Celsius and the exact method of preparation is as follows:
1. The mixing of the ingredients takes place in a double-walled container and. at a constant temperature for a period of twenty (20) to thirty (30) first minutes of the hour with a constant mixing rate.
2. Mixing should create a perfectly homogeneous mixture, and to achieve the desired result a vacuum and pressure mixer or homogenizer mixer or pressure cooker assemblies are designed to provide high quality productions of pharmaceutical preparations and cosmetics, gels, toothpaste, mascara, hair care products etc.
3. The mixing temperature should remain constant throughout the mixing as deviations adversely affect the result and the optimum temperature range is from twenty (20° C) to forty (40° C) degrees Celsius, preferably from twenty-five (25° C) to thirty-five (35° C) degrees Celsius, ideally from twenty-seven (27° C) to thirty-two (32° C) degrees Celsius.
4. The rotational speed during homogenization may be from 2800 rpm to 3100 rpm, preferably from 2850 rpm to 3050 rpm, ideally from 2900 rpm to 3000 rpm.
5. To avoid air bubbles in the final product and prolong the shelf life, it is recommended to use a vacuum pump with a vacuum pressure of -0.08Mpa.
6. The ingredients used and the quantities by weight and percent (%) are listed in table 1:
TABLE 1
7. The mixing sequence is as follows: first mix the first (1st) with the second (2nd) and then add the third (3rd) to the resulting mixture and then add the fifth (5th) to the resulting mixture component and then to the resulting mixture is added the fourth component (4th).
8. Goose fat should be golden in color without any foreign matter and be homogeneous, with a characteristic odor of goose. The goose fat treatment should be mild and have a maximum treatment temperature of eighty (80° C) degrees Celsius.
9. Sulfanilamide should be fine-grained, if it does not have the necessary granulometry characteristics, the friction component is converted to a finer powder, in particular less than thirty (30mm) microns, preferably less than twenty two (22mm), ideally the granulometry should be from sixteen microns (16mm) to twenty two microns (22mm) .
10. Olive oil is preferably 2-3% low-acid olive oil and even better Virgin Olive Oil, which is virgin olive oil, that is olive oil produced only by natural and mechanical processes, with good organoleptic characteristics, with a free acidity of not more than 2.0%, and even better Extra Virgin Olive Oil, which is virgin olive oil, produced solely by natural and mechanical processes, with a perfect aroma and taste, with a free acidity of not more than 0.8%.
11. The final moisture content of the ointment should be from 10% to 20% by weight, preferably from 12.5% to 17.5% by weight.
12. Place the above materials and quantities mentioned after mixing in containers or packaging and this finished product is ready for external dermatological use.
13. The above product, after being stored in the refrigerator, takes the form of a pale yellow aqueous ointment with a characteristic odor of goose and butter.
14. The above product, after its airtight packaging, remains active, in a refrigerator of four (4° C) degrees Celsius and at a temperature of up to twenty-five (25° C) degrees Celsius, in a shady and cool place for twelve (12) months.
15. The preservative used is potassium sorbate from 0.1% to 0.3% by weight, preferably from 0.1% to 0.2% by weight.
16. With the finished product as described above and in an amount of about one (1) gram per 5 square centimeters (cm2), apply on a suitable sterile cloth, preferably from hypoallergenic cotton, and place it in the affected area from the first day till healing of the wound, every 48 hours and within seven (7) to twenty-one (21) days results are apparent even in the third (3rd) degree burns. After healing unlike other methods the bum scar is no longer apparent.
17. The ointment is suitable for burns of all three degrees, as defined below based on the depth of the injury. In addition, it is also suitable for healing of other skin lesions such as openings in the skin caused by bedtime.
The ointment is suitable for:
- First degree burns, where the lesion is located on the most superficial layers of the skin, that is, on the superficial layers of the skin (epithelium). It manifests with signs of mild inflammation due to local vasodilation and is characterized by redness, edema of the area and tenderness. They are especially painful and they recede automatically in 2-3 days, which observed also skin peeling. They usually heal is one to two weeks, with apoptosis of the outer layers of the skin leaving visible scarring. With the use of ointment the healing time is reduced by 30-40% without leaving a visible scar.
-Second degree burns, where the lesion affects the skin deeper, epithelium and small or large part of the dermis. The irritation of the nerve endings creates intense pain while developing subcutaneous edema and forming bubbles containing serum fluid. The skin may be pink and wet or a mixture of red and white. Healing of these burns takes two or three weeks, if properly treated and the formation of scarring depends on the depth of the skin lesion. With the use of ointment, the healing time is reduced by 35-45% without leaving a scar.
-Third degree burns where the damage is related to all the thickness of the skin (skin, dermis and subcutaneous tissue). Sensitivity (pain) has been virtually eliminated due to destruction of nerve endings and the burn surface appears dry, pale or even charred. Healing takes place very slowly, scarring is always formed (hard crunchy) and skin transplantation may be required. With the use of ointment the healing time is reduced by 40-50% without leaving a visible scar.

Claims

1 . Ointment for the treatment of burns, produced by intense mixing and mild heat treatment of a fatty acid mixture consisting of 40% by weight vegetable oil, preferably rapeseed oil, water, 20% vegetable fats by palm oil and palm-kernel oil, milk butter, 0.3% by weight salt, emulsifiers, vitamins A, D, E, preservative preferably potassium sorbate, flavorings and coloring substances, citric acid, olive oil preferably extra virgin olive oil virgin olive oil produced only by natural and mechanical processes, with a free acidity of not more than 0,8%, pharmaceutical petroleum jelly, goose fat with salt and sulfanilamide, for the treatment of burns, formed by specific quantities of the above materials, namely:
2. To obtain the product according to claim 1, this mixture is subjected to intense mixing and mild heat treatment for a period of twenty (20) to thirty (30) minutes at a constant rate of mixing and after cooling the formed aqueous ointment is ready to pack and use.
3. A product obtained according to claim 1 with specific characteristics of its constituents and on the basis that the olive oil will preferably be 2-3% low-acid olive oil and even better virgin olive oil, i.e. olive oil produced only by natural and mechanical processes, by good organoleptic characteristics, with a free acidity of not more than 2.0%, and even better extra virgin olive oil, which is virgin olive oil, produced only by natural and mechanical processes, with a perfect aroma and taste with a free acidity of not more than 0,8%.
4. A product obtained according to claim 1 with specific characteristics of its constituents and based on the fact that the active substance sulfanilamide should have a particle size of less than thirty microns (30mm) preferably less than twenty two microns (22mm), ideally the granulometry should be is from sixteen to twenty two microns (16-22mm).
5. Product according to claim 1 for use in the rapid, painless and radical treatment of burns with the specific use of goose fat, an ingredient which, together with sulfanilamide, has beneficial effects on burns and other skin lesions. The combination of sulfanilamide with goose fat has healing effects and the efficacy of the product is multiplied by the above synergy.
6. Product obtained according to claim 1 for use in the rapid, painless and radical treatment of burns and with the ability to rapidly heal burns and / or residual lesions by pathophysiological reactions of skin tissues - by exogenous, high temperature, chemical effect radiation and electricity.
7. A product obtained according to claim 1 by the combined action of its constituents, which are olive oil, petroleum jelly, goose fat, sulfanilamide, rapeseed oil, vitamins A, D and E.
8. A product obtained according to claim 1 and in a specific mixing sequence which is as follows: first mix the first (1st) with the second (2nd) and then add the third (3rd) to the resulting mixture and then add the fifth (5th) to the resulting mixture component and then to the resulting mixture is added the fourth component (4th).
EP20718759.2A 2019-03-18 2020-03-13 Ointment for the treatment of burns Pending EP3952837A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GR20190100123A GR1009789B (en) 2019-03-18 2019-03-18 Ointment for burns
PCT/GR2020/000017 WO2020188305A1 (en) 2019-03-18 2020-03-13 Ointment for the treatment of burns

Publications (1)

Publication Number Publication Date
EP3952837A1 true EP3952837A1 (en) 2022-02-16

Family

ID=70285723

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20718759.2A Pending EP3952837A1 (en) 2019-03-18 2020-03-13 Ointment for the treatment of burns

Country Status (3)

Country Link
EP (1) EP3952837A1 (en)
GR (1) GR1009789B (en)
WO (1) WO2020188305A1 (en)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1525285A (en) * 1922-04-24 1925-02-03 Gabbola Raffaele Composition for use as a salve or ointment
US3761590A (en) 1970-05-18 1973-09-25 Research Corp Silver sulfadiazine used in the treatment of burns
US7357923B1 (en) * 1995-10-30 2008-04-15 Cac Pharmaceuticals Topical medicament for skin injuries and disorders
GR1004321B (en) * 2002-10-02 2003-08-28 Μιραντα Βασιλειου Μιχαλακοπουλου Ointment for healing burns
RU2337702C2 (en) * 2006-12-28 2008-11-10 Лидия Ибрагимовна Гайсанова Balsam "gaysanovoy", possessing wound healing, antiinflammatory and anti-burn activity
CN101642575A (en) * 2009-09-25 2010-02-10 惠连旺 Ointment shape medicinal substrate
RU2452475C2 (en) 2010-06-17 2012-06-10 Закрытое акционерное общество "СНС-фарма" Agent for wounds, burns and infectious inflammatory diseases of skin, appendages and mucous membranes
UA97076C2 (en) * 2011-04-22 2011-12-26 Светлана Владимировна Бабий Anti-inflammatory ointment based on sulfanilamide
CN102349920B (en) 2011-08-10 2013-11-13 成都第一药物研究所有限公司 Sulfanilamide medicament composition for wound surface
US11813284B2 (en) * 2013-08-08 2023-11-14 Novan, Inc. Topical compositions and methods of using the same
CN107929098A (en) * 2017-12-06 2018-04-20 杨益文 A kind of cosmetics and skincare product and the pharmaceutical composition for treating burn and scald
WO2019125313A1 (en) * 2017-12-21 2019-06-27 Caliskan Muharrem Burn treatment cream and production method thereof

Also Published As

Publication number Publication date
GR1009789B (en) 2020-08-03
WO2020188305A1 (en) 2020-09-24

Similar Documents

Publication Publication Date Title
US9283173B2 (en) Emulsified wax compositions and uses thereof
JP6778219B2 (en) Igai adhesive protein products that suppress skin inflammation and their applications
US20230338435A1 (en) Topical composition comprised of cod li ver oil for treating wounds and skin disorders
CN109219442A (en) Fish oil topical composition
KR20130055182A (en) Composition for improving acnes and kit for improving acnes containing the same
US6780444B1 (en) Method of making cosmetic, pharmaceutical, and dermatological compositions and compositions made according to the method
WO2020188305A1 (en) Ointment for the treatment of burns
KR20160041302A (en) Manufacturing method of cosmetic for acned skin containing hydrozol
RU2543355C1 (en) Dry face mask
KR102218008B1 (en) Manufacturing method of hydrogel mask pack by using aloe and hydrogel mask pack by the same
KR102215331B1 (en) Laser treatment for pain relief How to make cosmetics For pain application
KR101967576B1 (en) Anti-Atopy, Anti-microbial and Anti-inflammatory Cosmetic Composition Containing a White Rose Extract Stabilized with Lamella Liposome
RU2369377C1 (en) Phytobalsam insofit for skin regeneration
US20200188351A1 (en) Topical hair and skin formulation
RU2186561C2 (en) Cream for dry and normal face skin
KR100289906B1 (en) Dermatological composition
RU2182820C1 (en) Stimulating cosmetic cream
KR100592429B1 (en) Burn treatment comprising bamboo epidermal powder and its preparation method
KR102013406B1 (en) Composition for preventing hair loss and promoting hair growth
RU2157176C1 (en) Curative balsam
BE677435A (en)
HU228081B1 (en) Emulsion composition comprising elder-berry extract and alum and using for cosmetic treatment vein
Chatur et al. Research Article Formulation and Evaluation of Panchamrut Polyherbal Scrub.
FR2857261A1 (en) Cosmetic or pharmaceutical product, useful e.g. as a mask, comprising absorbant support impregnated with a composition containing active care agent
KR20040024160A (en) Germanium -containing cosmetic composition, and face pack produced therefrom

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: UNKNOWN

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20211222

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20240220