EP3866768A4 - Verwendung von reboxetin zur behandlung von narkolepsie - Google Patents

Verwendung von reboxetin zur behandlung von narkolepsie Download PDF

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Publication number
EP3866768A4
EP3866768A4 EP19874099.5A EP19874099A EP3866768A4 EP 3866768 A4 EP3866768 A4 EP 3866768A4 EP 19874099 A EP19874099 A EP 19874099A EP 3866768 A4 EP3866768 A4 EP 3866768A4
Authority
EP
European Patent Office
Prior art keywords
reboxetine
treat narcolepsy
narcolepsy
treat
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19874099.5A
Other languages
English (en)
French (fr)
Other versions
EP3866768A1 (de
Inventor
Herriot TABUTEAU
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Axsome Therapeutics Inc
Original Assignee
Axsome Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axsome Therapeutics Inc filed Critical Axsome Therapeutics Inc
Publication of EP3866768A1 publication Critical patent/EP3866768A1/de
Publication of EP3866768A4 publication Critical patent/EP3866768A4/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP19874099.5A 2018-10-15 2019-10-14 Verwendung von reboxetin zur behandlung von narkolepsie Pending EP3866768A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862745956P 2018-10-15 2018-10-15
PCT/US2019/056134 WO2020081461A1 (en) 2018-10-15 2019-10-14 Use of reboxetine to treat narcolepsy

Publications (2)

Publication Number Publication Date
EP3866768A1 EP3866768A1 (de) 2021-08-25
EP3866768A4 true EP3866768A4 (de) 2022-01-05

Family

ID=70284075

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19874099.5A Pending EP3866768A4 (de) 2018-10-15 2019-10-14 Verwendung von reboxetin zur behandlung von narkolepsie

Country Status (16)

Country Link
EP (1) EP3866768A4 (de)
JP (1) JP2022504975A (de)
KR (1) KR20210071046A (de)
CN (1) CN112888430A (de)
AU (2) AU2019361915A1 (de)
BR (1) BR112021007019A2 (de)
CA (1) CA3115983A1 (de)
CL (1) CL2021000924A1 (de)
CO (1) CO2021004681A2 (de)
CR (1) CR20210514A (de)
EC (1) ECSP21031200A (de)
IL (1) IL282311A (de)
MX (1) MX2021004207A (de)
PE (1) PE20211199A1 (de)
SG (1) SG11202103588WA (de)
WO (1) WO2020081461A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190381056A1 (en) 2018-06-17 2019-12-19 Axsome Therapeutics, Inc. Compositions for delivery of reboxetine
WO2021113163A1 (en) * 2019-12-03 2021-06-10 Axsome Therapeutics, Inc. Use of reboxetine to treat nervous system disorders
KR20230055668A (ko) * 2021-10-19 2023-04-26 단국대학교 천안캠퍼스 산학협력단 레복세틴을 유효성분으로 포함하는 근감소증의 예방 또는 치료용 조성물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6485746B1 (en) * 2000-08-25 2002-11-26 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
KR20070029740A (ko) * 2004-06-09 2007-03-14 화이자 인코포레이티드 통증 치료를 위한 레복세틴의 용도
SI2968208T1 (sl) * 2013-03-13 2023-02-28 Jazz Pharmaceuticals Ireland Limited, Zdravljenje katapleksije

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GARCIA-BORREGUERO D ET AL: "Effects of reboxetine in narcolepsy-cataplexy: Preliminary findings on 14 patients", SLEEP (ROCHESTER), vol. 24, no. Abstract Supplement, 15 April 2001 (2001-04-15), & 15TH ANNUAL MEETING OF THE ASSOCIATED PROFESSIONAL SLEEP SOCIETIES; CHICAGO, ILLINOIS, USA; JUNE 05-10, 2001, pages A323 - A324, XP009531711, ISSN: 0161-8105 *
O' GORMAN CEDRIC ET AL: "SCIENTIFIC RATIONALE AND CLINICAL DEVELOPMENT OF AXS-12 FOR NARCOLEPSY", SLEEP, vol. 42, no. Abstract Supplement, 1 January 2019 (2019-01-01), pages A24, XP055866024 *
SCHMIDT CHRISTIAN ET AL: "The norepinephrine reuptake inhibitor reboxetine is more potent in treating murine narcoleptic episodes than the serotonin reuptake inhibitor escitalopram", BEHAVIOURAL BRAIN RESEARCH, ELSEVIER, AMSTERDAM, NL, vol. 308, 23 April 2016 (2016-04-23), pages 205 - 210, XP029542431, ISSN: 0166-4328, DOI: 10.1016/J.BBR.2016.04.033 *

Also Published As

Publication number Publication date
JP2022504975A (ja) 2022-01-13
IL282311A (en) 2021-05-31
SG11202103588WA (en) 2021-05-28
PE20211199A1 (es) 2021-07-01
KR20210071046A (ko) 2021-06-15
EP3866768A1 (de) 2021-08-25
CA3115983A1 (en) 2020-04-23
WO2020081461A1 (en) 2020-04-23
AU2023200917A1 (en) 2023-03-23
CN112888430A (zh) 2021-06-01
AU2019361915A1 (en) 2021-05-13
ECSP21031200A (es) 2021-05-31
CL2021000924A1 (es) 2021-09-03
CR20210514A (es) 2021-11-12
MX2021004207A (es) 2021-08-11
BR112021007019A2 (pt) 2021-07-13
CO2021004681A2 (es) 2021-06-21

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