EP3862428A4 - Verfahren zur verlängerung des telomers einer zelle - Google Patents
Verfahren zur verlängerung des telomers einer zelle Download PDFInfo
- Publication number
- EP3862428A4 EP3862428A4 EP19868942.4A EP19868942A EP3862428A4 EP 3862428 A4 EP3862428 A4 EP 3862428A4 EP 19868942 A EP19868942 A EP 19868942A EP 3862428 A4 EP3862428 A4 EP 3862428A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- cell
- telomere
- extending
- extending telomere
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004027 cell Anatomy 0.000 title 1
- 210000003411 telomere Anatomy 0.000 title 1
- 102000055501 telomere Human genes 0.000 title 1
- 108091035539 telomere Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0608—Germ cells
- C12N5/0611—Primordial germ cells, e.g. embryonic germ cells [EG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
- C12N5/0629—Keratinocytes; Whole skin
- C12N5/063—Kereatinocyte stem cells; Keratinocyte progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0656—Adult fibroblasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2521/00—Culture process characterised by the use of hydrostatic pressure, flow or shear forces
- C12N2521/10—Sound, e.g. ultrasounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20180117265 | 2018-10-02 | ||
KR1020190108764A KR102209234B1 (ko) | 2018-10-02 | 2019-09-03 | 세포의 텔로미어를 신장시키는 방법 |
PCT/KR2019/011681 WO2020071652A1 (ko) | 2018-10-02 | 2019-09-10 | 세포의 텔로미어를 신장시키는 방법 |
Publications (3)
Publication Number | Publication Date |
---|---|
EP3862428A1 EP3862428A1 (de) | 2021-08-11 |
EP3862428A4 true EP3862428A4 (de) | 2021-11-10 |
EP3862428B1 EP3862428B1 (de) | 2024-02-28 |
Family
ID=70292168
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19868942.4A Active EP3862428B1 (de) | 2018-10-02 | 2019-09-10 | Verfahren zur verlängerung des telomers einer zelle |
EP19869268.3A Pending EP3862429A4 (de) | 2018-10-02 | 2019-09-19 | Zusammensetzung zur verlängerung des telomers einer zelle und herstellungsverfahren dafür |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19869268.3A Pending EP3862429A4 (de) | 2018-10-02 | 2019-09-19 | Zusammensetzung zur verlängerung des telomers einer zelle und herstellungsverfahren dafür |
Country Status (2)
Country | Link |
---|---|
EP (2) | EP3862428B1 (de) |
KR (2) | KR102209234B1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3945132A1 (de) | 2020-07-29 | 2022-02-02 | Konkuk University Industry- Academic Cooperation Foundation | Mikrofluidisches system, verfahren zur hemmung, verzögerung oder umkehrung der zellulären seneszenz unter verwendung eines mikrofluidischen systems und so erhaltene zelle |
WO2022032337A1 (en) * | 2020-08-11 | 2022-02-17 | Royal Melbourne Institute Of Technology | Stimulating cellular production of exosomes |
KR102674715B1 (ko) * | 2023-10-06 | 2024-06-13 | 휴먼바이오텍 주식회사 | 줄기세포의 텔로미어의 길이를 신장시키는 방법 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006066247A2 (en) * | 2004-12-17 | 2006-06-22 | Exvivo Technologies | Methods and compositions for extending telomere length and increasing cell lifespan |
WO2016000075A1 (en) * | 2014-07-03 | 2016-01-07 | Dan Grebenisan | System and method for increasing the length of telomeres |
WO2018057542A1 (en) * | 2016-09-20 | 2018-03-29 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LT2437606T (lt) * | 2009-05-18 | 2016-10-10 | Telomerase Activation Sciences, Inc. | Kompozicijos ir būdai skirti didinti telomerazės aktyvumą |
JP2016514953A (ja) * | 2013-02-22 | 2016-05-26 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | テロメア伸長に関する化合物、組成物、方法及びキット |
KR101632108B1 (ko) * | 2013-07-03 | 2016-06-27 | 서울대학교병원 | 인간 세포의 줄기세포능을 증대시키는 방법 |
EP3380102A4 (de) * | 2015-11-25 | 2019-05-08 | The Methodist Hospital System | Telomerverlängerung und entzündungshemmende mittel zur zellregenerierung |
KR102050852B1 (ko) * | 2016-03-11 | 2019-12-03 | 주식회사 스템온 | 세포 리프로그래밍 장치 |
KR101855967B1 (ko) * | 2016-03-11 | 2018-05-10 | 가톨릭관동대학교산학협력단 | 물리적 자극에 의한 환경유입을 이용한 세포 리프로그래밍 방법 |
-
2019
- 2019-09-03 KR KR1020190108764A patent/KR102209234B1/ko active IP Right Grant
- 2019-09-10 EP EP19868942.4A patent/EP3862428B1/de active Active
- 2019-09-19 KR KR1020190115381A patent/KR102228136B1/ko active IP Right Grant
- 2019-09-19 EP EP19869268.3A patent/EP3862429A4/de active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006066247A2 (en) * | 2004-12-17 | 2006-06-22 | Exvivo Technologies | Methods and compositions for extending telomere length and increasing cell lifespan |
WO2016000075A1 (en) * | 2014-07-03 | 2016-01-07 | Dan Grebenisan | System and method for increasing the length of telomeres |
WO2018057542A1 (en) * | 2016-09-20 | 2018-03-29 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders |
Non-Patent Citations (3)
Title |
---|
BROCK J. SISHC ET AL: "Telomeres and Telomerase in the Radiation Response: Implications for Instability, Reprograming, and Carcinogenesis", FRONTIERS IN ONCOLOGY, vol. 5, 24 November 2015 (2015-11-24), pages 1 - 19, XP055586183, DOI: 10.3389/fonc.2015.00257 * |
NEUHOF D ET AL: "Telomerase activity and telomere length in human lymphoblasts after irradiation", INTERNATIONAL JOURNAL OF RADIATION: ONCOLOGY BIOLOGY PHYSICS, PERGAMON PRESS, USA, vol. 48, no. 3, 1 January 2000 (2000-01-01), pages 276, XP027402761, ISSN: 0360-3016, [retrieved on 20000101] * |
V KH KHAVINSON ET AL: "Epithalon Peptide Induces Telomerase Activity and Telomere Elongation in Human Somatic Cells", BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, vol. 135, no. 6, 1 June 2003 (2003-06-01), US, pages 590 - 592, XP055579199, ISSN: 0007-4888, DOI: 10.1023/A:1025493705728 * |
Also Published As
Publication number | Publication date |
---|---|
KR102209234B1 (ko) | 2021-02-01 |
EP3862428B1 (de) | 2024-02-28 |
EP3862429A4 (de) | 2021-11-10 |
EP3862428A1 (de) | 2021-08-11 |
KR20200038172A (ko) | 2020-04-10 |
KR20200038180A (ko) | 2020-04-10 |
EP3862429A2 (de) | 2021-08-11 |
KR102228136B1 (ko) | 2021-03-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL276600A (en) | Methods for producing T cells | |
EP3375028A4 (de) | Verfahren zur vorbereitung einer kathode für eine sekundärbatterie | |
EP3561918A4 (de) | Prälithiationsverfahren für eine anode für eine sekundärbatterie | |
EP3545569A4 (de) | Verfahren zur herstellung einer anodenaufschlämmung für eine sekundärbatterie | |
EP3743082A4 (de) | Verfahren zur verwendung für car-t-zellen | |
EP3472173A4 (de) | Beschichtungen für bauteile elektrochemischer zellen | |
EP3254320A4 (de) | Verfahren zur herstellung von anoden für lithiumbatterien | |
EP3824080A4 (de) | Verfahren zur analyse von zellen | |
EP3751001A4 (de) | Verfahren zur herstellung von ergothionin | |
EP3604216A4 (de) | Herstellungsverfahren für festelektrolyt mit li3ps4 | |
EP3605703A4 (de) | Herstellungsverfahren für festelektrolyt auf lgps-basis | |
EP3783727A4 (de) | Verfahren zur aktivierung einer sekundärbatterie | |
EP3491177A4 (de) | Verfahren zur elektrochemischen abscheidung | |
EP3573163A4 (de) | Verfahren zur herstellung einer monozelle | |
EP3862428A4 (de) | Verfahren zur verlängerung des telomers einer zelle | |
EP3868889A4 (de) | Verfahren zur aktivierung/proliferation von t-zellen | |
EP3778902A4 (de) | Zellproduktionsverfahren | |
EP3843580A4 (de) | Verfahren zum entwurf von einlegesohlen | |
IL274746A (en) | A method for cell culture | |
EP3842522A4 (de) | Verfahren zur herstellung von regulatorischen t-zellen | |
EP3831931A4 (de) | Zellproduktionsverfahren | |
EP3747991A4 (de) | Verfahren zur induktion von zellen | |
EP3508569A4 (de) | Verfahren zur herstellung von mikroglia aus pluripotenten stammzellen | |
EP3846924A4 (de) | Verfahren zur kontinuierlichen zellkultur | |
EP3808839A4 (de) | Verfahren zur herstellung von transformierten zellen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
17P | Request for examination filed |
Effective date: 20210409 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20211011 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12N 5/077 20100101ALI20211005BHEP Ipc: C12N 13/00 20060101AFI20211005BHEP |
|
DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
17Q | First examination report despatched |
Effective date: 20220808 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: GRANT OF PATENT IS INTENDED |
|
INTG | Intention to grant announced |
Effective date: 20231115 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE PATENT HAS BEEN GRANTED |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R096 Ref document number: 602019047513 Country of ref document: DE |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: LT Ref legal event code: MG9D |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20240628 |
|
REG | Reference to a national code |
Ref country code: NL Ref legal event code: MP Effective date: 20240228 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20240228 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20240529 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: HR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20240228 Ref country code: RS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20240528 Ref country code: NL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20240228 |