EP3852714A1 - Anti-wrinkle composition - Google Patents
Anti-wrinkle compositionInfo
- Publication number
- EP3852714A1 EP3852714A1 EP19787083.5A EP19787083A EP3852714A1 EP 3852714 A1 EP3852714 A1 EP 3852714A1 EP 19787083 A EP19787083 A EP 19787083A EP 3852714 A1 EP3852714 A1 EP 3852714A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- acetyl
- composition
- extract
- formulation
- formulation according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Definitions
- the present invention describes a composition comprising acetyl sh-heptapeptide-1 , acetyl hexapeptide-8 , and extract of sea buckthorn (Hippophae rhamnoides L.) kernels.
- a formulation in the form of a face mask, serum or cream comprising the composition of the invention, and the use of said formulation to achieve one or more of the following cosmetic effects: fleshed skin, hydration, luminosity, regeneration, face oval redesigning, reduction of signs of aging.
- Figures 1 to 3 show the results related to immediate clinical parameters and long-term instrumental parameters .
- composition comprising: acetyl sh-heptapeptide-1 , acetyl hexapeptide-8 , and extract of sea buckthorn (Hippophae rhamnoides L.) kernels .
- said composition can further comprise one or more of the ingredients selected from: hydrogenated lecithin and/or shea butter.
- a further object of the present invention consists of formulations comprising the above composition, wherein said formulations are in the form of face masks, serum, cream.
- each of the above mentioned three components: acetyl sh-heptapeptide-1, acetyl hexapeptide-8, and extract of sea buckthorn (Hippophae rhamnoides L.) kernels, hydrogenated lecithin and shea butter, can be included in a formulation of the invention in a percentage between about 0.05 and 12% weight/volume, and preferably between about 2 and 10% weight/volume .
- said formulation comprises:
- said formulation comprises :
- the formulations of the invention further comprise one or more of the excipients selected from: consistency factors, emulsifiers, preservatives, oils and fat phase, perfumes or essences, water.
- said excipients are included in an amount as follows:
- the excipients are selected from the group comprising: glycerin, glyceryl polyacrylate, ethyl hexyl glycerin, butylene glycol, propyl heptyl caprylate, propylene glycol, phenoxyethanol , chlorphenesin, methyl parabens, sodium polyacrylate, maltodextrins , sodium diphosphate, sodium phosphate, caprylyl glycol, EDTA, disodium EDTA, cetearyl alcohol, glyceryl stearate, peg 100 stearate, biosaccharide gum-1 ethylhexyl palmitate, tocopheryl acetate, xylitol, ceramide 3, ceramide 6 II, ceramide 1, phytosphingosine, cholesterol, sodium lauroyl lactylate, carbomer, xanthan gum, octadecene dioic acid, sodium h
- a formulation in the form of a face mask is described .
- said "face mask” formulation can comprise further components selected from the group comprising: clay, kaolin, cucumber, birch extract, green tea, witch hazel, burdock, sage and tea tree oil, amylaceous substances, pectins, dog rose extract, antioxidants, hyaluronic acid, collagen, alpha-hydroxy acids such as mandelic acid, glycolic acid, citric acid, tartaric acid, beta-hydroxy acids, such as salicylic acid, oil of Argania spinosa kernel, oil of Gossypium herbaceum seeds.
- said formulation is a day or night face cream or is a serum.
- said "face cream” and/or “serum” formulations comprise further active ingredients selected from the group comprising: glycolic acid, hyaluronic acid, kojic acid, salicylic acid, alpha hydroxy acids (AHA), antioxidants such as for example: vitamin A, vitamin C, vitamin E, alpha-lipoic acid, coenzyme Q10, ferulic acid, phloretin, citric acid, ceramides, silicone derivatives, green tea extract, hydroquinone, beta hydroxy acids (Bhas), peptides, copper peptides, retinoids.
- active ingredients selected from the group comprising: glycolic acid, hyaluronic acid, kojic acid, salicylic acid, alpha hydroxy acids (AHA), antioxidants such as for example: vitamin A, vitamin C, vitamin E, alpha-lipoic acid, coenzyme Q10, ferulic acid, phloretin, citric acid, ceramides, silicone derivatives, green tea extract,
- compositions and formulations for the treatment of skin aging described the use of the composition and formulations for the treatment of skin aging.
- such a treatment is a cosmetic treatment.
- composition according to the present invention is for use in a cosmetic method in order to achieve one or more of the following cosmetic effects: fleshed skin, hydration, luminosity, regeneration, face oval redesigning, reduction of signs of aging.
- composition according to the present invention has been shown to have both a short- and a long-term effect in reducing wrinkle visibility.
- the tested composition comprises acetyl sh-heptapeptide- 1, acetyl hexapeptide-8 and extract of sea buckthorn (Hippophae rhamnoides L.) kernels.
- the eye contour wrinkle volume was instrumentally evaluated after 21 and 42 days of use.
- Treatment method the composition was applied overnight in a monolayer on the face and eye contour and left on for 20 minutes. A massage was then performed to spread well the residue, without a final rinse. During the day, the volunteers applied a SPF50+ protection.
- Instrument parameters at time [to] (basal value) and after prolonged use of the product: after 21 days [t 2i ] , after 42 days [ t 4 2 ] , measurements of wrinkle volume were performed. Data are studied with Antera 3D® and processed with Antera 3D® software. Antera 3D® is a camera capturing high-resolution images. The instrument is able to acquire three-dimension images so as to obtain parameters related to expression lines, wrinkles and furrows (skin characteristics which are hollow with respect to the normal skin surface) . Measurements of the volume of a wrinkle are expressed in mm 3 .
- the established acceptability threshold is 5%.
- the "wrinkle visibility" parameter was analyzed according to the following criteria:
- the Table in Figure 2 shows data referred to the eye contour wrinkles, the visibility of which is reduced, even if not statistically significantly reduced, in 25% of the volunteers immediately after the use of the product .
- Wrinkle volume is reduced by 8% after 21 days of use of the product (not statistically significant) , and statistically significantly by 17% after 42 days of use of the product. Data are shown in the Table in Figure 3. Self-evaluations
- composition according to the present invention In order to show the synergic effect achieved by the composition according to the present invention, the following parameters were evaluated in a comparative test, on a homogeneous sample of subjects.
- the observed parameters were: fleshed skin, hydration, luminosity, regeneration, face oval redesigning, reduction of signs of aging.
- the tested compositions are:
- the treatment was carried out for 56 days, with applications repeated twice a day.
- the same team monitored the 4 treatment groups.
- composition A is capable of generating a "fleshed skin” effect, not occurring with any one of the other compositions tested for comparative purposes.
- the composition according to the present invention leads to a marked effect of face oval redesigning and reduction of signs of aging.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
Description
Claims
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT201800008773 | 2018-09-20 | ||
PCT/IB2019/057965 WO2020058923A1 (en) | 2018-09-20 | 2019-09-20 | Anti-wrinkle composition |
Publications (1)
Publication Number | Publication Date |
---|---|
EP3852714A1 true EP3852714A1 (en) | 2021-07-28 |
Family
ID=64557066
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19787083.5A Pending EP3852714A1 (en) | 2018-09-20 | 2019-09-20 | Anti-wrinkle composition |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP3852714A1 (en) |
WO (1) | WO2020058923A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115364015A (en) * | 2022-09-23 | 2022-11-22 | 广州品尚生物科技发展有限公司 | Anti-wrinkle cream and preparation method thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2943255B1 (en) * | 2009-03-17 | 2012-02-24 | Rocher Yves Biolog Vegetale | COSMETIC USE OF A HIPPOPHAE EXTRACT |
KR101276141B1 (en) * | 2011-06-13 | 2013-06-18 | 동국대학교 산학협력단 | Seed extract of seabuckthorn and method for producing the same |
US20160243023A1 (en) * | 2015-02-19 | 2016-08-25 | Elc Management Llc | Novel Skin Remodeling Strategy |
-
2019
- 2019-09-20 EP EP19787083.5A patent/EP3852714A1/en active Pending
- 2019-09-20 WO PCT/IB2019/057965 patent/WO2020058923A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2020058923A1 (en) | 2020-03-26 |
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Legal Events
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STAA | Information on the status of an ep patent application or granted ep patent |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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STAA | Information on the status of an ep patent application or granted ep patent |
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17P | Request for examination filed |
Effective date: 20210305 |
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AK | Designated contracting states |
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RAV | Requested validation state of the european patent: fee paid |
Extension state: TN Effective date: 20210305 Extension state: MA Effective date: 20210305 |