EP3826757A1 - Mischapparat, mischanlage und verfahren zum mischen von substanzen in geschlossenen behältern - Google Patents
Mischapparat, mischanlage und verfahren zum mischen von substanzen in geschlossenen behälternInfo
- Publication number
- EP3826757A1 EP3826757A1 EP19742060.7A EP19742060A EP3826757A1 EP 3826757 A1 EP3826757 A1 EP 3826757A1 EP 19742060 A EP19742060 A EP 19742060A EP 3826757 A1 EP3826757 A1 EP 3826757A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- plate
- mixer
- base plate
- retainer
- holder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title claims description 11
- 239000000126 substance Substances 0.000 title description 10
- 238000003780 insertion Methods 0.000 claims description 16
- 230000037431 insertion Effects 0.000 claims description 16
- 239000012530 fluid Substances 0.000 claims description 8
- 125000006850 spacer group Chemical group 0.000 description 5
- 230000000295 complement effect Effects 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 239000004033 plastic Substances 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 239000003708 ampul Substances 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000013610 patient sample Substances 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/20—Mixing the contents of independent containers, e.g. test tubes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/20—Mixing the contents of independent containers, e.g. test tubes
- B01F31/23—Mixing the contents of independent containers, e.g. test tubes by pivoting the containers about an axis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/20—Mixing the contents of independent containers, e.g. test tubes
- B01F31/201—Holders therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/22—Control or regulation
- B01F35/221—Control or regulation of operational parameters, e.g. level of material in the mixer, temperature or pressure
- B01F35/2214—Speed during the operation
- B01F35/22142—Speed of the mixing device during the operation
- B01F35/221422—Speed of rotation of the mixing axis, stirrer or receptacle during the operation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
- B01F35/32—Driving arrangements
- B01F35/325—Driving reciprocating or oscillating stirrers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/40—Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
- B01F35/42—Clamping or holding arrangements for mounting receptacles on mixing devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
Definitions
- the present invention relates to a mixer
- the swivel table includes individual ones
- Diameters or the swivel table includes a pattern of
- An ampoule can be used to hold the holder
- the ampoules are removed be confused from the holder.
- the insertion and removal of the ampoules are time-consuming.
- An object of the present invention is to provide a mixer in which the
- Mixing apparatus a mixing system, and a method for operating a mixing apparatus or a mixing system are defined by the features of further claims.
- a mixer according to the invention comprises one
- Drive unit with a drive and with a shaft pivotable about a pivot axis, which is operatively connected to the drive, a pivot holder which is arranged on the shaft, the pivot axis being oriented essentially horizontally, the pivot holder being a base plate and at least one spaced apart therefrom
- Retainer comprises, wherein the pivot mount is designed such that holders for containers in the direction of the pivot axis between the base plate and the
- At least one retainer can be inserted.
- the drive unit comprises a housing in which an electro-mechanical drive, with or without a gear, is arranged.
- the drive unit can
- the swivel mount can be swiveled around the swivel axis by any angle in both directions. That the swivel mount can be pivoted back and forth by any angle, for example by means of the drive unit, or the swivel mount can be rotated one or more times around the pivot axis in one of the two directions of rotation.
- Powders or fluids such as suspensions or emulsions, can therefore be mixed. For example, whole blood, i.e.
- Blood plasma or blood serum can be mixed with blood cells on their own or with additional substances.
- the substances to be mixed can be filled into test tubes or ampoules.
- Prick ampoules include glass or plastic containers, which are closed at the top with a lid that includes a septum.
- the septum comprises a soft plastic, for example made of PTFE or silicone, which can be pierced with a pipette needle or tip. For example, such Screw the lid onto the open-topped container with a thread.
- the mixing apparatus comprises a control unit with which the swivel angle, the
- Swivel speed and the swivel direction are adjustable. By setting these values, an optimal mixture of substances can be achieved.
- Pivot axis are aligned and into which the holder for containers can be inserted.
- the receptacles comprise elevations which can protrude into recesses in the holder which are complementary thereto.
- the elevations are elements that extend directly from the base plate of the swivel mount.
- the bumps can be pens
- the elevations can also be slot nuts, for example for T-slots or dovetail slots. Alternatively, the
- Recordings include recesses, into which complementary elevations the holder can protrude, and which
- the receptacles include first receptacles which are arranged in a region of the base plate near the shaft and second receptacles, which are arranged in an area of the base plate that is remote from the shaft.
- the holders can be inserted into the first receptacle with a first end and into the second receptacle with a second end. So they are
- several receptacles are arranged next to one another in a direction transverse to the pivot axis.
- several identical or different holders can be inserted next to each other in the swivel holder, whereby the contents of several containers can be mixed at the same time.
- the recordings are arranged symmetrically with respect to the pivot axis.
- the mixing apparatus comprises first spacers, which can be inserted into the receptacles and into which the holders for the containers can be inserted, and second spacers, which are located between the receptacles
- the spacers increase the distance between the inserted holder and the base plate of the swivel mount. This is advantageous if shorter vessels and the upper end are to be inserted into the holder the vessels used are essentially the same
- a drive plate is provided in a first end region of the base plate
- the base plate is through the drive plate with the at least one retainer
- a support element is provided in a second end region of the base plate opposite the first end region, which has a cylindrical
- the base plate is through the support element with the at least one retainer
- the support element comprises a plate which is oriented essentially perpendicular to the base plate and to the pivot axis.
- the support element comprises a central opening and the base plate protrudes at least partially through the central opening.
- At least one connector is provided which connects the drive plate to the
- Support element connects.
- the drive plate comprises
- Drive plate can be provided, in which the at least one retainer is held or with which the
- At least one retainer is guided or clamped.
- elevations can be ribs or pins.
- the support element comprises
- fixation for fastening the at least one retainer.
- a fixation can comprise an at least partially detachable element.
- the fixation can be pivotable and can comprise a fixing element.
- a fixation can also be provided on the drive plate, with which the at least one retainer can be detachably fastened.
- the mixing apparatus comprises a bearing unit with at least one roller, on which the support element with the lateral surface is rotatably mounted.
- the storage unit is located with respect to the swivel mount Drive unit opposite.
- the support element is pivotally mounted in alignment with the shaft in the bearing unit. Due to the double-sided mounting of the swivel mount, the corresponding bearings and the swivel mount need to be dimensioned a few stable, which means that they take up less space and less mass has to be moved.
- the bearing unit comprises two or more rollers on which the support element with the
- Shell surface is rotatably mounted. At least one of the rollers can be spring-loaded. At least one of the rollers can be driven synchronously with the drive unit.
- the drive unit and the bearing unit are arranged on a common connecting plate.
- the connecting plate can be continuous
- Retainer at least one plate with at least one through opening, the through openings being arranged in such a way that, when the holders are inserted, they are aligned with those formed in the holders
- Container receptacles are aligned.
- the inner dimensions of the through openings are smaller than the inner dimensions of the container receptacles of the insertable holders.
- Dimensions of the through opening can also be smaller than the outer dimensions of the lid of the container.
- Retainers a first plate and a second plate, wherein the distance between the base plate and the first plate is greater than that between the base plate and the second plate.
- the two plates can be independent of one another or can be connected to one another.
- the first plate and the second plate are formed together in one piece.
- the at least one rib can be in one or both lateral edge areas of each plate
- ribs can be arranged between the two edge regions of each plate.
- the at least one tab can be arranged in one or both of the two free ends of the retainer.
- the mixer includes
- the mixer comprises
- At least one locking device with which the position of the
- Swivel mount can be fixed.
- the mixer comprises
- At least one holder for containers which is inserted between the base plate and the at least one retainer.
- the at least one holder can also be inserted into the receptacles.
- each holder comprises a plurality of container receptacles which are arranged along a longitudinal axis and are formed between the two ends.
- the container receptacles can for example be countersunk holes with a circular cross section. However, other cross sections are also possible.
- Each container receptacle can comprise at least one lateral opening, which extends laterally outwards from the respective container receptacle transversely to the longitudinal axis.
- the at least one opening can be a slot or a window.
- Each container receptacle can comprise two lateral openings which are arranged opposite one another with respect to the longitudinal axis and which, together with the container receptacle, form a passage in the holder.
- a slot and a window, two slots or two windows can be assigned to each container receptacle.
- a clamping tab can be provided which projects through the window into the respective container receptacle, as a result of which a container accommodated therein can be clamped therein.
- a tab plate on the holder be arranged, which includes all clamping tabs.
- clamping tabs can be formed together in one piece with the rest of the holder.
- the mentioned embodiments of the mixing apparatus can be used in any combination, provided they do not contradict each other.
- a mixing plant according to the invention comprises one
- the mixing plant can comprise a working surface which is arranged on the machine stand and the mixing apparatus is arranged on the working surface.
- the mixing plant comprises one
- the pipetting unit comprises a transport unit, on which pipette tips are arranged, and with which the pipette tips in the
- the mixing plant comprises one
- Reading unit with which markings from those of
- Containers to be mixed are readable.
- the markings can be selected from the group comprising 1D barcode, 2D barcode, RFID tag and the like.
- the reading unit can also recognize markings which are attached to the holders for receiving the containers. With the reading unit can also be seen in which position the container holder holds a container and which position is empty. It can also be seen whether all of the holders for containers pushed into the mixer are completely inserted between the base plate and the retainer.
- Mixing apparatus or a mixing plant includes the
- the insertion can be an insert, for example if the swivel mount comprises cylindrical pins and the holder is provided with correspondingly complementary bores.
- the insertion can also be an insertion, for example if the swivel receptacle comprises sliding blocks and the holder is provided with a correspondingly complementary groove.
- the method comprises
- fastening elements can be removed, which fix the retaining element in the corresponding receptacles, and the retaining element can then be lifted off and placed at a different location independently of the mixing apparatus.
- fastening elements can be removed, which fix the retaining element in the corresponding receptacles, and the retaining element can then be lifted off and placed at a different location independently of the mixing apparatus.
- it can
- Retaining element can be linearly pushed away from the area above the swivel mount by means of a displacement mechanism. In another alternative, this can
- the retaining element is arranged in a fixed manner on the swivel receptacle, then the holder must be pushed into the swivel receptacle under the retaining element, for example along the swivel axis.
- the method comprises the step:
- each container can be held in a specific position in the holder and accordingly in the swivel mount or in the
- Swivel mount can be inserted. If reading is done before insertion, make sure that the holder is inserted correctly. To prevent incorrect insertion, the first and second shots of the Pivot mount and, accordingly, the first and second ends of the holder can be configured differently.
- markings can be read, which are applied to the holders.
- the method comprises
- the content of a mother tube which contains, for example, whole blood, on its own or with
- part of the whole blood can go from the mother tube to one
- the daughter tube can be empty beforehand or can contain a substance such as a reagent. The contents of the daughter tube can then be mixed again. After mixing, the holder with the containers arranged therein can be removed from the mixing apparatus and fed to an analysis device. For removing and / or supplying fluids from containers through a lid
- Pipette needle The mentioned embodiments of the method can be used in any combination, provided they do not contradict each other.
- Fig. 1 is a perspective view of a
- FIG. 2 shows the mixer of FIG. 1 without a drive, without a retainer and without a reading unit
- FIG. 3A shows the retainer of FIG. 1
- 3C shows a sectional view of the mixing apparatus of FIG. 1 transversely to the axis, through a high and a low container;
- FIG. 4 shows a perspective view of a second embodiment of a swivel mount with an alternative retainer
- Fig. 5 is a bottom perspective view of the
- FIG. 6 shows a holder with containers inserted therein as in FIG. 2; and Fig. 7 an inventive mixing plant.
- the mixing apparatus 100 comprises a drive unit 1 with a drive 10, a control unit 12 and with a shaft 11 which can be pivoted about a substantially horizontal pivot axis A and which is operatively connected to the drive 10.
- the mixing apparatus 100 further comprises a swivel mount 2, which is arranged on the shaft 11.
- the swivel mount 2 includes one
- a circular disk-shaped drive plate 21 connects the shaft 11 to the base plate 20.
- the drive plate 21 is essentially perpendicular to the swivel pocket A and essentially perpendicular to the base plate 20. At the end of the drive plate 21 opposite
- Swivel mount 2 is a circular disc
- Support plate 22 is provided, which is aligned parallel and aligned with the drive plate 21.
- a retaining plate with holes is detachably arranged between the drive plate 21 and the support plate 22.
- the retainer 4 can be fixed with a pivotable fixing 211 and in the Support plate 22 with a pivotable fixation 222.
- elevations 200 are provided in the form of slot nuts.
- a reading unit 82 with a limiter 83 is provided on the opposite side of the support plate 22.
- the reading unit 82 can mark on the holder 3 and / or on the containers arranged in the holder 3
- the support plate 22 is supported on two rollers 50 of a bearing unit 5 and rotatably supported.
- the drive unit 1, the bearing unit 5, the reading unit 82 and the limiter 83 are on a common one
- Connection plate 6 arranged.
- FIG. 2 shows the mixing apparatus 100 of FIG. 1 without the housing and the drive 10 of the drive unit 1, without the retainer 4, without the reading unit 82 and without the
- the drive plate 21 and the support plate 22 are connected to one another by two rod-shaped connectors 23.
- the connectors 23 are designed and arranged such that the retainer 4 can lie evenly on both connectors 23 in the installed state.
- a pattern of T-nuts 200 is arranged on the base plate 20 of the swivel mount 2.
- a double row of sliding blocks is arranged in both end regions of the base plate 20 and a single row in a central one
- FIG. 1 shows the retainer 4 of Figure 1.
- Retainer 4 comprises a bent plate with holes 40, with two first plates 41, or with two edge plates 41, and with a second plate 42, or with a central plate 42.
- the two edge plates 41 are aligned
- Retainers 4 are provided with continuous tabs 43 which are in alignment with the corresponding plates. Ribs 44 extend essentially along the entire length of the retainer at the lateral outer boundary of the respective edge plate 41
- one-piece design of the retainer 4 each form a rib 44 in the respective transition region due to the offset of the first plate 41 to the second plate 42.
- FIG. 3B shows an alternative embodiment of the retainer 4 of FIG. 1 with only a first plate 41 and a second plate 42.
- tabs 43 are separate from one another
- only one rib 44 is also formed in the transition region between the two plates 41, 42.
- FIG. 3C shows a sectional view of the mixing apparatus 100 of FIG. 1 transverse to the axis A, through a high one
- the high container 7 is inserted between the base plate 20 and the first plate 41 of the retainer 4 and the low one Container 70 between base plate 20 and second plate 42 of retainer 4.
- FIG. 4 shows a perspective view of a second embodiment of a swivel mount 2 with an alternative retainer 400.
- Grooves 210 are provided in the drive plate 21, into which the retainers 400
- a fixation 222 is provided on the support plate 22, with which the retainers 400 can be detachably fastened.
- the connectors 23 are designed as laterally arranged round bars.
- a central opening 221 is provided in the support plate 22, through which the base plate 20 projects and through which the holders for containers can be inserted. In the variant of the swivel mount 2 shown, holders with high containers can be inserted into the retainers 400. Should be deeper
- the retainers 400 must be rotated 180 degrees such that the outward surface of the plate 401 faces the base plate 20 and that the open end of the retainer 400 faces the drive plate 21.
- FIG. 5 shows a perspective bottom view of the retainer 400 from FIG. 4.
- the retainer 400 comprises a plate 401 with a slot 402 which extends essentially over the entire length of the plate.
- the width of the slot 402 is smaller than the outer dimensions of the container closures and is larger than the piercing area of the container closures.
- ribs 403 extend over essentially the entire length of the Retainer 400.
- a first free end of the retainer 400 is open and a second free end opposite the first free end is laterally
- a first tab 404 is provided, which is parallel and slightly offset from the plate 401 in the area of the plate
- Retainer 400 protrudes beyond this.
- a second tab 405 At the closed end of the retainer 400 is a second tab 405
- Figure 6 shows a holder with inserted therein
- the holder 3 extends along the longitudinal axis L, has container receptacles 32 which comprise two lateral slots 320 and has clamping tabs 322 which are formed integrally with the rest of the holder 3 and which in the interior of the
- Container receptacles 32 protrude.
- the holder 3 comprises a groove 33 which is arranged on the underside of the holder 3, ie on the side of the holder 3 which lies opposite the container receptacles 32.
- a T-slot is shown.
- a dovetail groove or another retaining groove can also be provided.
- the groove 33 extends along the longitudinal axis L, at least over the region of the holder 3, which comprises the container receptacles 32.
- the groove 33 is open at the first end 30 of the holder 3, so that the elevations 200 of the swivel receptacle 2 can be easily moved into the groove 33.
- a handle 34 is arranged with which the holder 3 can be easily gripped by hand.
- a recess 340 is provided in the handle 34, which enables the reading unit 82 to recognize that the holder 3 is completely inserted into the swivel mount 2.
- FIG. 7 shows a perspective view of a
- non-pivoted mixing apparatus 100 Both apparatuses are arranged with receiving elements 800 on the work surface 80, which are arranged on the machine stand 8.
- the mixing system further comprises the pipetting unit 81 with the transport unit 810 and the pipette tips 811.
- the transport unit 810 can move the pipette tips 811 above the work surface 80 in a first horizontal direction X, in a second horizontal direction Y and in a vertical direction Move towards Z.
- the transport unit 810 can move the pipette tips 811 above the work surface 80 in a first horizontal direction X, in a second horizontal direction Y and in a vertical direction Move towards Z.
- the reading unit 82 is also aligned and fixed with the receiving elements 800 on the work surface 80. In front of the reading unit 82, holders can be pushed over the receiving element 800 in order to recognize the markings on the holders 3 and / or on the container arranged in the holders 3.
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Accessories For Mixers (AREA)
Abstract
Description
Claims
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP23159223.9A EP4218996B1 (de) | 2018-07-25 | 2019-07-24 | Mischapparat, mischanlage und verfahren zum mischen von substanzen in geschlossenen behältern |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18185420.9A EP3599013A1 (de) | 2018-07-25 | 2018-07-25 | Mischapparat, mischanlage und verfahren zum mischen von substanzen in geschlossenen behältern |
PCT/EP2019/069871 WO2020020923A1 (de) | 2018-07-25 | 2019-07-24 | Mischapparat, mischanlage und verfahren zum mischen von substanzen in geschlossenen behältern |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP23159223.9A Division EP4218996B1 (de) | 2018-07-25 | 2019-07-24 | Mischapparat, mischanlage und verfahren zum mischen von substanzen in geschlossenen behältern |
EP23159223.9A Division-Into EP4218996B1 (de) | 2018-07-25 | 2019-07-24 | Mischapparat, mischanlage und verfahren zum mischen von substanzen in geschlossenen behältern |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3826757A1 true EP3826757A1 (de) | 2021-06-02 |
EP3826757B1 EP3826757B1 (de) | 2023-04-26 |
Family
ID=63047178
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP18185420.9A Withdrawn EP3599013A1 (de) | 2018-07-25 | 2018-07-25 | Mischapparat, mischanlage und verfahren zum mischen von substanzen in geschlossenen behältern |
EP21191494.0A Pending EP3932532A1 (de) | 2018-07-25 | 2018-07-25 | Mischapparat, mischanlage und verfahren zum mischen von substanzen in geschlossenen behältern |
EP19742060.7A Active EP3826757B1 (de) | 2018-07-25 | 2019-07-24 | Mischapparat, mischanlage und verfahren zum mischen von substanzen in geschlossenen behältern |
EP23159223.9A Active EP4218996B1 (de) | 2018-07-25 | 2019-07-24 | Mischapparat, mischanlage und verfahren zum mischen von substanzen in geschlossenen behältern |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP18185420.9A Withdrawn EP3599013A1 (de) | 2018-07-25 | 2018-07-25 | Mischapparat, mischanlage und verfahren zum mischen von substanzen in geschlossenen behältern |
EP21191494.0A Pending EP3932532A1 (de) | 2018-07-25 | 2018-07-25 | Mischapparat, mischanlage und verfahren zum mischen von substanzen in geschlossenen behältern |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP23159223.9A Active EP4218996B1 (de) | 2018-07-25 | 2019-07-24 | Mischapparat, mischanlage und verfahren zum mischen von substanzen in geschlossenen behältern |
Country Status (4)
Country | Link |
---|---|
US (1) | US11969700B2 (de) |
EP (4) | EP3599013A1 (de) |
CN (2) | CN116550196A (de) |
WO (1) | WO2020020923A1 (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10967341B2 (en) * | 2018-07-25 | 2021-04-06 | Tecan Trading Ag | Mixing device |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3226094A (en) * | 1963-08-01 | 1965-12-28 | Royal Alexandra Hosp Children | Warming and shaking apparatus |
FR2692358B1 (fr) * | 1992-06-11 | 1995-08-04 | Abx Sa | Dispositif de transfert, d'agitation et de prelevement d'echantillons de produits sanguins en tubes regroupes dans des cassettes, notamment pour analyseurs hematologiques. |
US5918979A (en) * | 1997-02-27 | 1999-07-06 | Scientific Industries Inc. | Combination mechanical rotator-rocker |
US6793893B2 (en) * | 1999-10-12 | 2004-09-21 | Crystal Spring Colony Farms Ltd. | Semen storage |
US6893613B2 (en) * | 2002-01-25 | 2005-05-17 | Bristol-Myers Squibb Company | Parallel chemistry reactor with interchangeable vessel carrying inserts |
US7121713B2 (en) * | 2004-02-27 | 2006-10-17 | United States Gypsum Company | Swinging agitator for a gypsum calcining apparatus and the like |
US8246919B2 (en) * | 2006-09-21 | 2012-08-21 | Abbott Laboratories | Specimen sample rack |
FR2907905B1 (fr) * | 2006-10-30 | 2009-04-03 | C2 Diagnostics Sa | "appareil et procede pour manipuler des tubes,notamment appareil automate d'analyse sanguine" |
WO2010048631A2 (en) * | 2008-10-24 | 2010-04-29 | Biomicro, Inc. | Modular system for performing laboratory protocols and associated methods |
US8028843B2 (en) * | 2009-05-15 | 2011-10-04 | Hamilton Company | Shift and scan test tube rack apparatus and method |
US9144801B2 (en) * | 2010-08-31 | 2015-09-29 | Abbott Laboratories | Sample tube racks having retention bars |
CN201891228U (zh) * | 2010-09-30 | 2011-07-06 | 福建弘景木塑科技股份有限公司 | 一种组合式长城板 |
WO2012064940A1 (en) * | 2010-11-12 | 2012-05-18 | Gen-Probe Incorporated | System and method for tracking items during a process |
JP5678248B2 (ja) * | 2010-12-21 | 2015-02-25 | メディカテック株式会社 | 試験管撹拌装置 |
CN103084105A (zh) * | 2011-11-07 | 2013-05-08 | 杨杰 | 一种试管旋转摇床 |
DE102012013680A1 (de) * | 2012-07-11 | 2014-01-16 | Euroimmun Medizinische Labordiagnostika Ag | Vorrichtung sowie Verfahren zur Inkubation von Patientenproben |
CN103519831B (zh) * | 2013-10-24 | 2015-07-22 | 杭州晟维东智能科技有限公司 | 一种采血设备 |
FR3025170B1 (fr) * | 2014-08-28 | 2016-08-12 | Renault Sa | Assemblage d'inserts de renfort par un materiau polymere, notamment pour face avant technique de vehicule, cet assemblage etant renforce par sa fixation a un element de structure |
CN106233132B (zh) * | 2014-12-17 | 2020-03-03 | 默克有限公司 | 生物体分子分析装置 |
LU92703B1 (en) * | 2015-04-29 | 2016-10-31 | Stratec Biomedical Ag | Intelligent rack |
FR3043782B1 (fr) | 2015-11-13 | 2017-12-08 | Horiba Abx Sas | Dispositif d'agitation et de prelevement d'echantillons de liquides biologiques adapte pour trier |
CN108211946A (zh) * | 2016-01-12 | 2018-06-29 | 梁艳 | 检验科用混药振荡器 |
US9776188B1 (en) * | 2016-03-29 | 2017-10-03 | Heathrow Scientific Llc | Adjustable test tube holder |
CN206139043U (zh) * | 2016-09-21 | 2017-05-03 | 成松音 | 一种具有控温功能的涂料搅拌机 |
CN107913626B (zh) * | 2016-10-10 | 2021-05-14 | 深圳开立生物医疗科技股份有限公司 | 一种试管排混匀装置 |
CN206274302U (zh) * | 2016-12-23 | 2017-06-23 | 深圳市雷诺华科技实业有限公司 | 摇匀结构及糖化血红蛋白分析仪 |
JP6444437B2 (ja) * | 2017-01-10 | 2018-12-26 | 富士夫 堀 | 容器回転装置 |
CN206701173U (zh) * | 2017-05-16 | 2017-12-05 | 陈小丽 | 一种医学检验用液体样品放置处理架 |
CN107628285A (zh) * | 2017-09-08 | 2018-01-26 | 安徽华瑞医药技术开发有限公司 | 一种瓶装粉剂药品生产用均质振荡装置 |
CN107703266A (zh) * | 2017-09-27 | 2018-02-16 | 龙里县逸轩生产力促进中心 | 一种可适应不同长度试管的食品检测用试管震荡设备 |
CN108144547B (zh) * | 2018-03-16 | 2020-04-28 | 蓝天 | 一种医学试管摇匀装置 |
US10967341B2 (en) * | 2018-07-25 | 2021-04-06 | Tecan Trading Ag | Mixing device |
-
2018
- 2018-07-25 EP EP18185420.9A patent/EP3599013A1/de not_active Withdrawn
- 2018-07-25 EP EP21191494.0A patent/EP3932532A1/de active Pending
-
2019
- 2019-07-24 US US17/261,325 patent/US11969700B2/en active Active
- 2019-07-24 EP EP19742060.7A patent/EP3826757B1/de active Active
- 2019-07-24 WO PCT/EP2019/069871 patent/WO2020020923A1/de active Application Filing
- 2019-07-24 CN CN202310636479.7A patent/CN116550196A/zh active Pending
- 2019-07-24 EP EP23159223.9A patent/EP4218996B1/de active Active
- 2019-07-24 CN CN201980048278.7A patent/CN112469496B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
EP3932532A1 (de) | 2022-01-05 |
CN112469496B (zh) | 2023-06-16 |
US11969700B2 (en) | 2024-04-30 |
EP3599013A1 (de) | 2020-01-29 |
EP4218996A1 (de) | 2023-08-02 |
CN116550196A (zh) | 2023-08-08 |
EP3826757B1 (de) | 2023-04-26 |
EP4218996B1 (de) | 2024-07-31 |
WO2020020923A1 (de) | 2020-01-30 |
CN112469496A (zh) | 2021-03-09 |
US20210260541A1 (en) | 2021-08-26 |
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