EP3632248B1 - Masque médical de type à barrière et à évacuation (et variantes) - Google Patents

Masque médical de type à barrière et à évacuation (et variantes) Download PDF

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Publication number
EP3632248B1
EP3632248B1 EP18810853.4A EP18810853A EP3632248B1 EP 3632248 B1 EP3632248 B1 EP 3632248B1 EP 18810853 A EP18810853 A EP 18810853A EP 3632248 B1 EP3632248 B1 EP 3632248B1
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EP
European Patent Office
Prior art keywords
frame
mask
face
medical
air
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP18810853.4A
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German (de)
English (en)
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EP3632248A1 (fr
EP3632248C0 (fr
EP3632248A4 (fr
Inventor
Vladimir Egorovich BELOUSOV
Maksim Vladimirovich BELOUSOV
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Mpointaero Inc
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Mpointaero Inc
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Publication of EP3632248A4 publication Critical patent/EP3632248A4/fr
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Publication of EP3632248B1 publication Critical patent/EP3632248B1/fr
Publication of EP3632248C0 publication Critical patent/EP3632248C0/fr
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Classifications

    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D13/00Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches
    • A41D13/05Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches protecting only a particular body part
    • A41D13/11Protective face masks, e.g. for surgical use, or for use in foul atmospheres
    • A41D13/1107Protective face masks, e.g. for surgical use, or for use in foul atmospheres characterised by their shape
    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D13/00Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches
    • A41D13/05Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches protecting only a particular body part
    • A41D13/11Protective face masks, e.g. for surgical use, or for use in foul atmospheres
    • A41D13/1107Protective face masks, e.g. for surgical use, or for use in foul atmospheres characterised by their shape
    • A41D13/1138Protective face masks, e.g. for surgical use, or for use in foul atmospheres characterised by their shape with a cup configuration
    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D13/00Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches
    • A41D13/05Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches protecting only a particular body part
    • A41D13/11Protective face masks, e.g. for surgical use, or for use in foul atmospheres
    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D13/00Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches
    • A41D13/05Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches protecting only a particular body part
    • A41D13/11Protective face masks, e.g. for surgical use, or for use in foul atmospheres
    • A41D13/1161Means for fastening to the user's head
    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D2400/00Functions or special features of garments
    • A41D2400/38Shaping the contour of the body or adjusting the figure

Definitions

  • the claimed group of inventions relates to human personal protective equipment, namely to face masks intended to be used predominantly in medicine.
  • This invention represented in three versions, is:
  • each version of the mask is a hollow frame.
  • barrier medical face masks and framed face masks are available from the background art.
  • a respiratory face mask is known from document CN2162260 Y published on 04.20.1994 , which is intended for nasal and oral breathing. It consists of two boxed side frames combined into an integral structure with through holes, and a rigid shield located between them in front of the nasal-oral area.
  • the mask is functionally divided into the front, right, and left sectors, where the left sector and the right sector represent the side containers that contain the filtering elements. All the exhaled air is removed (similarly to a respirator) via valves, and the inhaled air is filtered.
  • a partition situated between the containers acts as a partial barrier (shield) to protect the surface of the face against moisture penetration from outside.
  • JP 2005 185381 aims to provide a mask which can be worn for a long period of time without the user feeling stuffy and which prevents dispersion of expiration to others.
  • the mask is provided with a mask body which comprises a jaw pad part and a mouth front development part, and an attachment string; the mask body has a morphological stability capable of retaining the form of itself; the jaw pad part is formed into a shape applied to the jaw of a person from the lower part to stabilize the mask body; the mouth front development part is formed into a form that extends from the jaw pad part to the nose front with its upper part separated from the face and develops from the mouth front to the nose front to be worn; and the attachment string is disposed in such a positional relation that the adjacency of the jaw pad part is pulled from the ear till abutting on the jaw and stabilized.
  • the mask body is a single part and is not configured as a hollow frame.
  • the attachment string passes through a hole in the mask. This hole is not suitable for the passage of air
  • a medical framed barrier and discharge face mask as defined by claim 1.
  • medical framed barrier and discharge face masks as defined by claims 10 and 12.
  • Optional features are defined by the dependent claims.
  • Standard filter medical masks due to their design features, lack the possibility of protecting the general population against viral infections and a number of hazardous bacteria, which is most relevant during epidemics.
  • the claimed technical results are achieved via the design embodiment of the medical face mask according to three options, each of which complements or focuses the capabilities of the previous one, while providing it with new consumer properties.
  • All the mask options have one common inventive concept; namely, they contain a hollow frame that forms an under-mask space for the lower part of the face, which is made in the form of a channel, with an airtight outer surface and an inner surface (closest to the surface of the face) made of breathable fabric.
  • the frame channel contains an air inlet and outlet on each side (on the left and on the right) for the airflows that are formed during inhalation/exhalation. As a rule, the side that comes into contact with the surface of the face has a cutout around the mouth.
  • each version of the mask is made in the form of a hollow frame.
  • a separate zone for nasal respiration is formed, which may be open, half-open, or closed.
  • the face mask is positioned on the head in such a way that the exhaled air is almost entirely expelled backwards, to an area that is safe for people around the wearer.
  • the face mask is universal, i.e. it is intended for use by the general population as well as in medical institutions. It may be applied as the basic version (the simplest one) or may be a combination of a frame mask and additional components.
  • the mask frame covers the lower part of the face, providing complete protection only to the mouth area - the main source of airborne infections and the gateway for the penetration of infections from outside.
  • nasal respiration has been left entirely unimpeded, which is especially important for healthy wearers with undamaged nasal mucosa.
  • the mask frame sides are extremely short by comparison with the prototype.
  • the hollow mask frame consists of two parts, which form its outer side and inner side, which comes into direct contact with the surface of the face.
  • the outer part of the frame is airtight and is generally made from transparent medical plastic, thus improving the wearer's communicative abilities. If mask transparency is irrelevant, its outer portion may, for example, be made of a dense cloth or paper.
  • the inner part of the frame i.e. the side that comes into contact with the surface of the face, is made of breathable and, generally, elastic fabric, for example, spunbond fabric or medical gauze.
  • a cutout around the mouth area may be located on the side that comes into contact with the surface of the face. If a fabric with low breathing resistance is used for the inside of the frame (for example, 1- or 2-ply gauze), then a cut in the mouth area is not appropriate.
  • the mask may have special devices for folding it: from a dimensional to a flat shape.
  • the outer part of the frame may have folds in the form of corrugations or pleats.
  • the mask (without any additional components) is mainly intended for the civilian population, for example, to prevent the spread of an influenza epidemic in public areas.
  • the additional components of the mask increase its protective properties, thus extending the scope of application to include medical facilities.
  • the frame of the mask for the lower face part 1 includes the outer air-impermeable side of the frame 2 (shown transparent), made of plastic, for example, through which the inner breathable side of the frame 3 can be seen. This may be made, for example, of fabric and come into contact with surface of the face. It is provided with a cutout 4 around the mouth area. On both sides of the head, the frame forms lateral air holes (inlet/outlet) 5 for the passage of the air flow.
  • the nasal area is fully open, i.e. nasal inhalation and exhalation are unhampered.
  • the upper edge of the frame which passes directly under the nose, partially expels the air that is exhaled through the nose due to its geometry.
  • the breathable material of the mask may be either single-ply or consist of several layers, each of which may have various useful properties, for example, bactericidal action against different types of microbes, etc. All the materials applied (in each of the layers) are identical to those that are widely used in medical practice and have the appropriate certificates.
  • the plastic and fabric parts of the mask may be factory joined (stitched, glued) or be connected by the wearer himself/herself, for example, by using adhesive tape.
  • the mask is attached/fixed on the wearer's head area using devices 9, for example, ties, straps, elastic bands, etc.
  • This version of the mask is primarily intended for use in surgery and boasts the maximum protection for the doctor and patient in the conditions of surgical operations. It is aimed at the maximum preservation of the working capacity of medical staff.
  • This option is a combination of two types of mask: frame and shield-shaped, forming two different mask spaces: the lower frame, in the mouth area, and the shield, in the nose area.
  • a partition is formed between the shield and the frame, containing an air opening for passage of air that is exhaled through the nose into the frame cavity.
  • a valve may be installed to direct the air that is exhaled through the nose towards the frame and prevent the penetration of any air exhaled through the mouth into the under-mask space.
  • the shield is airtight and is located at some distance from the surface of the face, so that nasal breathing remains practically unimpeded.
  • the main purpose of the mask shield is to direct (by virtue of its aerodynamics) the air exhaled from the nose directly into the cavity of the frame, which completely prevents it from getting towards the surgical field. This solution allows a surgeon to maintain a high quality of the main (nasal) type of breathing during surgery, while enhancing his/her performance.
  • the shield protects the nasal area and also partially protects the middle part of the face from external pathological factors during surgery: biological fluids, airborne infections, etc. This is also relevant to improving the surgeon's safety.
  • the air exhaled by the personnel in contrast to filter masks, is fully discharged into the non-sterile area of the surgery room. This ensures a high level of sterility in the surgery area itself, i.e. it contributes to a reduction in the risk of post-surgery complications. Consequently, the overall quality of treatment provided by a medical facility is improved.
  • the frame of the mask that is located in the lower face part 1 includes the outer airproof part of the frame 2 (shown transparent), which can be made of, for example, plastic, and through which the inner breathable side of the frame 3 can be seen. This is made, for example, of a fabric material and has a cutout 4 around the mouth area. On both sides of the head, the frame forms lateral air holes (inlet/outlet) 5 for the passage of the air flow.
  • the sides of the frame are as elongated as possible.
  • the frame also has an air-impermeable shield 10, which covers the lower part of the nose.
  • an air-impermeable shield 10 which covers the lower part of the nose.
  • a partition between the shield 10 and the frame 11 with an air opening There can be multiple similar openings in the partition, which might be identical or take various shapes.
  • Fig. 2 shows that the shield 10 is located at some distance from the surface of the face, thus forming a slotted space.
  • air freely penetrates through this slotted space.
  • all air due to the aerodynamic properties of the shield, is directed from top to bottom, through the air opening in the partition 11. It goes into the frame cavity and then exits through the side air openings 5 (inlet/outlet) for air flow passage.
  • the main purpose of this version of the mask is general clinical utilization.
  • the mask can be recommended for use in all types of medical institutions, including departments of infectious disease and for the provision of all types of medical care, from outpatient to infection surgery. It is intended to maximize the protection of medical staff without significant loss of its performance capacity.
  • a particular feature of this mask option is its ability to transform and adapt to specific working conditions of medical staff.
  • This type of mask is a hybrid consisting of three types of masks: frame, shield-shaped, and filter. Accordingly, it combines the functions of all types of well-known medical masks: barrier and discharge, barrier, and filter.
  • the frame of the mask that is located in the lower face part 1 includes the outer airproof part of the frame 2 (shown transparent), which can be made of, for example, plastic, and through which the inner breathable side of the frame 3 can be seen. This is made, for example, of a fabric material and has a cutout 4 around the mouth area. On both sides of the head, the frame forms lateral air holes (inlet/outlet) 5 for the passage of the air flow.
  • This mask version can be used in two states: initial (open) and working (closed).
  • the shield 10 In the initial position, the shield 10 does not come in contact with the surface of the face and inlets/outlets 5 are open to allow the passage of air flows.
  • the shield 10 made of filtering and, as a rule, single-ply material (for example, spunbond fabric or medical gauze), fits tightly to the contour of the face around the dorsum nasi. As a result, the mask space in the nasal area is fully closed, and nasal inhalation/exhalation occurs through the filter fabric of the shield.
  • a partition 11 is formed between the shield and the frame, which, as distinct from version No. 2, may not contain an air opening.
  • the outer side of the side sections of the frame consists of segments 12 made of filter fabrics (side filters).
  • the wall of each segment 12 may consist of filters of different densities or of a different number of layers of fabrics (for example, spunbond fabric).
  • a device 14 for closing the channel is located on the outer boundary 13 of each segment (shown only for the middle segment). As a result, during oral inhalation/exhalation, air passes only through the side filters 12.
  • shaping supports for example, a coarse mesh of nylon
  • the mesh can be woven into the fabric in the form of individual fibers, or the fabric itself, in the form of a mesh, may be soaked in a shaping solution (for example, starch).
  • the breathable material of the frame, the filters in the side segments, and the shield may be made of fabrics with different functional properties or of the same fabrics (used in medical practice as standard).
  • the shield does not come into contact with the surface of the face in the area of the dorsum nasi.
  • the resulting gap is used not only used to supply air during nasal inhalation, but also to allow for the free movement of the plastic part such that it can follow the movements of the lower jaw.
  • the connection between the mask parts does not impede the free movement of the lower jaw, which allows for communication during surgery, for example.
  • the shield 10 is made of fabric with a degree of surplus so as not to impede the movement of the lower jaw during conversation.
  • Each version of the mask may have various additional devices or features and may be made of different materials, or using different technologies.
  • the plastic part of the mask may have an additional structure in the form of a transparent shield.
  • the outer side of the mask may be fully or partially transparent; it may be made of plastic, as shown in figures 1-3 .
  • the plastic may be of different colors, and various inscriptions and images may be printed on it.
  • the plastic may be non-transparent (using any color scheme).
  • the outer side of the frame in front of the mouth area may be a movable wall in the form of a membrane that can oscillate in sync with breathing.
  • the part of the frame that comes into contact with the surface of the face may be made from a solid fabric or net (fine- or coarse-meshed) out of cotton fabric, for example, or a transparent or semi-transparent natural fabric (e.g. silk, batiste, chiffon etc.), or a synthetic polymer (e.g. nylon, capron, etc.).
  • a solid fabric or net fine- or coarse-meshed out of cotton fabric, for example, or a transparent or semi-transparent natural fabric (e.g. silk, batiste, chiffon etc.), or a synthetic polymer (e.g. nylon, capron, etc.).
  • components for shaping and reinforcing the mark may pass between the layers of breathable material.
  • the mask frame cavity may contain at least one device for the optimization and separation of the air flows, for example, one or multiple partitions, air channels, etc.
  • At least one filtration component may be installed along the air flow path in the frame channel, which can be further treated with an antiseptic agent, for example, or developed with a filtration material that is used in the manufacture of medical masks (for example, spunbond fabric).
  • an antiseptic agent for example, or developed with a filtration material that is used in the manufacture of medical masks (for example, spunbond fabric).
  • At least one air channel within the mask frame may contain at least one moisture-absorbing element.
  • Any air channel within the mask frame may contain at least one inlet or outlet valve.
  • At least one tube for the forced supply of an air mixture to the respiratory organs from an external source and/or for the forced discharge of exhaled air from the under-mask space may be attached to at least one air channel within the mask frame.
  • At least one air channel within the mask frame may additionally contain at least one compressed air bottle to improve the composition of the inhaled air in standalone mode or in field (combat) conditions.
  • At least one air channel within the mask frame may also contain at least one fan.
  • At least one air channel may be made in the form of a spiral, which would make foreign particles in the inhaled air moving in a rotational (centrifugal) manner and settle on the channel's walls.
  • At least one air channel within the mask frame may contain at least one zero-resistance filter.
  • the inner surface of the frame channel may be treated with a special adhesive that promotes the superficial adhesion of dust and various biological aerosols contained in the air.
  • the mask frame may additionally be electrostatically treated to ensure the superficial precipitation of dust particles and other foreign particles contained in the passing air flow and possessing the opposite electrical potential.

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Textile Engineering (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)

Claims (13)

  1. Un masque facial médical à barrière sur cadre et à décharge qui est un cadre creux (2, 3) qui forme un espace sous le masque dans la zone du visage, le cadre creux étant constitué de deux parties (2, 3) qui forment son côté externe (2) et son côté interne (3) ; le cadre creux (2, 3) est réalisé sous la forme d'au moins un canal contenant l'entrée et la sortie d'air comportant des trous d'air (5) latéraux pour le passage du flux d'air, dans lequel le cadre creux forme l'espace sous le masque pour la partie inférieure du visage, en outre, le côté externe (2) du cadre est imperméable à l'air, et le côté qui vient en contact avec la surface du visage (3) est réalisé en matériau respirant ; et dans lequel le cadre creux (2,3) est configuré de sorte que, en utilisation, le côté interne (3) vient en contact avec la surface du visage et l'air entrant à travers les trous d'air latéraux (5) passe à travers le au moins un canal.
  2. Masque médical selon la revendication 1, dans lequel le côté du cadre qui entre en contact avec la surface du visage (3) a une découpe (4) autour de la bouche.
  3. Masque médical selon la revendication 1, dans lequel le matériau respirant (6) s'étend au-delà du cadre.
  4. Masque médical selon les revendications 1 et 3, dans lequel au moins une entrée et/ou une sortie contient un composant (6) supplémentaire qui dirige l'air expiré vers le matériau qui entre en contact avec la surface du visage. Le composant s'étend au-delà du cadre.
  5. Masque médical selon la revendication 3, dans lequel un matériau respirant (6) qui s'étend au-delà du cadre contient un dispositif supplémentaire (7) pour retenir l'humidité de l'air expiré.
  6. Masque médical selon la revendication 1, dans lequel la face externe du cadre présente des plis sous forme d'ondulations ou de plis.
  7. Masque médical selon la revendication 1, contenant au moins un dispositif (9) pour la fixation du masque à la zone de la tête.
  8. Masque facial selon la revendication 1, dans lequel le cadre qui vient en contact avec la surface du visage (3) est hygroscopique.
  9. Masque facial selon la revendication 1, dans lequel le côté externe (2) du cadre est intégralement ou partiellement transparent.
  10. Un masque facial médical à barrière sur cadre et à décharge qui est un cadre creux (2, 3) qui forme un espace sous le masque dans la zone du visage, le cadre creux étant constitué de deux parties (2, 3) qui forment son côté externe (2) et son côté interne (3) ; et qui est réalisé sous la forme d'au moins un canal contenant une entrée et une sortie comprenant des trous d'air latéraux (5) pour le passage du flux d'air, dans lequel le cadre (2, 3) contient en outre un bouclier (10), qui, en utilisation, ferme au moins la partie inférieure du nez et qui forme une partition (11) avec le cadre, la partition contenant au moins une ouverture d'air ; dans lequel le cadre creux (2,3) est configuré de sorte que, en utilisation, le côté interne (3) vient en contact avec la surface du visage et que l'air entrant à travers les trous d'air latéraux (5) passe à travers le au moins un autre canal.
  11. Masque médical selon la revendication 10, dans lequel au moins une valve est présente dans au moins une ouverture d'air.
  12. Un masque facial médical à barrière sur cadre et à décharge qui est un cadre creux (2, 3) qui forme un espace sous le masque dans la zone du visage, le cadre creux étant constitué de deux parties (2, 3) qui forment son côté externe (2) et son côté interne (3) ; et qui est réalisé sous la forme d'au moins un canal contenant une entrée et une sortie comprenant des trous d'air latéraux (5) pour le passage du flux d'air, dans lequel le masque facial médical à barrière sur cadre et à décharge contient un bouclier (10), qui est formé avec la possibilité de contact le long du contour du visage autour du dorsum nasi et qui forme une partition (11) avec le cadre (2, 3), dans lequel le côté externe du cadre, dans la zone buccale, est imperméable à l'air, et l'autre partie est réalisée en matériau filtrant et, dans lequel le au moins un canal a au moins un dispositif (14) qui lui permet d'être fermé.
  13. Masque médical selon la revendication 12, dans lequel l'écran est réalisé dans un matériau filtrant (12). 1
EP18810853.4A 2017-05-30 2018-04-24 Masque médical de type à barrière et à évacuation (et variantes) Active EP3632248B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2017118581A RU2652975C2 (ru) 2017-05-30 2017-05-30 Медицинская маска каркасная барьерно-отводящего типа (варианты)
PCT/RU2018/000267 WO2018222081A1 (fr) 2017-05-30 2018-04-24 Masque médical de type à barrière et à évacuation (et variantes)

Publications (4)

Publication Number Publication Date
EP3632248A1 EP3632248A1 (fr) 2020-04-08
EP3632248A4 EP3632248A4 (fr) 2021-03-17
EP3632248B1 true EP3632248B1 (fr) 2024-03-20
EP3632248C0 EP3632248C0 (fr) 2024-03-20

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EP18810853.4A Active EP3632248B1 (fr) 2017-05-30 2018-04-24 Masque médical de type à barrière et à évacuation (et variantes)

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EP (1) EP3632248B1 (fr)
JP (1) JP2020523492A (fr)
KR (1) KR20200028341A (fr)
BR (1) BR112019025140A2 (fr)
CA (1) CA3100189A1 (fr)
RU (1) RU2652975C2 (fr)
WO (1) WO2018222081A1 (fr)

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WO2021188560A1 (fr) 2020-03-16 2021-09-23 Mpointaero, Inc. Respirateur
CA3076157A1 (fr) * 2020-03-16 2021-09-16 Rodney HERRING Masque pour proteger un utilisateur contre les pathogenes dans l`air
WO2021194460A1 (fr) * 2020-03-24 2021-09-30 Иван Иванович КОТУРБАЧ Masque de protection multi-usages à utilisations multiples
KR102188598B1 (ko) 2020-04-21 2020-12-08 충북대학교 산학협력단 에어쉴드 기능을 갖는 기능성 마스크
GR20200100219A (el) * 2020-05-04 2021-12-09 Μαρκος Δημητριου Κυριαζης Μασκα προστασιας με εμπροσθια οπη χειλαναγνωσης
RU206135U1 (ru) * 2021-03-12 2021-08-24 Федеральное государственное бюджетное образовательное учреждение высшего образования "Российский государственный аграрный университет - МСХА имени К.А. Тимирязева" (ФГБОУ ВО РГАУ - МСХА имени К.А. Тимирязева) Маска медицинская
NL1043982B1 (nl) * 2021-03-29 2022-10-12 M D Meulenbelt Beschermend masker
KR20220147262A (ko) 2021-04-27 2022-11-03 (주)대한솔루션 피부트러블 방지용 마스크
IT202100013817A1 (it) * 2021-05-27 2022-11-27 Sports Fanatic Srl Maschera protettiva per uso sportivo
WO2023033705A1 (fr) * 2021-09-02 2023-03-09 Stefan Witte Masque facial

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RU32368U1 (ru) * 2003-06-26 2003-09-20 ЗАО "Управление промышленной собственности" ИНДИВИДУАЛЬНАЯ ЗАЩИТНАЯ МАСКА (варианты)
RU2240160C1 (ru) 2003-08-27 2004-11-20 Белоусов Владимир Егорович Средство защиты от негативных воздействий воздушного потока
JP2005185381A (ja) * 2003-12-25 2005-07-14 Hidetaka Takeno マスク

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EP3632248A1 (fr) 2020-04-08
BR112019025140A2 (pt) 2020-06-16
RU2652975C2 (ru) 2018-05-03
KR20200028341A (ko) 2020-03-16
RU2017118581A (ru) 2017-11-24
JP2020523492A (ja) 2020-08-06
WO2018222081A1 (fr) 2018-12-06
CA3100189A1 (fr) 2018-12-06
EP3632248C0 (fr) 2024-03-20
EP3632248A4 (fr) 2021-03-17

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