EP3493790A4 - Methods for the preparation of liposomes - Google Patents

Methods for the preparation of liposomes Download PDF

Info

Publication number
EP3493790A4
EP3493790A4 EP17837525.9A EP17837525A EP3493790A4 EP 3493790 A4 EP3493790 A4 EP 3493790A4 EP 17837525 A EP17837525 A EP 17837525A EP 3493790 A4 EP3493790 A4 EP 3493790A4
Authority
EP
European Patent Office
Prior art keywords
liposomes
preparation
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP17837525.9A
Other languages
German (de)
French (fr)
Other versions
EP3493790A1 (en
Inventor
Indu Javeri
Kaliappanadar Nellaiappan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Curirx Inc
Original Assignee
Curirx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/226,364 external-priority patent/US10143652B2/en
Application filed by Curirx Inc filed Critical Curirx Inc
Publication of EP3493790A1 publication Critical patent/EP3493790A1/en
Publication of EP3493790A4 publication Critical patent/EP3493790A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP17837525.9A 2016-08-02 2017-08-01 Methods for the preparation of liposomes Pending EP3493790A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15/226,364 US10143652B2 (en) 2009-09-23 2016-08-02 Methods for the preparation of liposomes
PCT/US2017/044865 WO2018026794A1 (en) 2016-08-02 2017-08-01 Methods for the preparation of liposomes

Publications (2)

Publication Number Publication Date
EP3493790A1 EP3493790A1 (en) 2019-06-12
EP3493790A4 true EP3493790A4 (en) 2020-03-25

Family

ID=61073551

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17837525.9A Pending EP3493790A4 (en) 2016-08-02 2017-08-01 Methods for the preparation of liposomes

Country Status (5)

Country Link
EP (1) EP3493790A4 (en)
JP (1) JP7019201B2 (en)
CN (1) CN109562067A (en)
CA (1) CA3032810A1 (en)
WO (1) WO2018026794A1 (en)

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
WO2006099169A2 (en) * 2005-03-10 2006-09-21 Mebiopharm Co., Ltd. Novel liposome compositions
WO2007127272A2 (en) * 2006-04-24 2007-11-08 The Cbr Institute For Biomedical Research Method of producing immunoliposomes and compositions thereof
US20080279927A1 (en) * 2002-12-31 2008-11-13 Bharat Serums & Vaccines Ltd Non-Pegylated Long-Circulating Liposomes
WO2009038779A2 (en) * 2007-09-19 2009-03-26 University Of Tennessee Research Foundation Methods and compositions for inhibiting undesirable cellular proliferation by targeted liposome delivery of active agents
WO2009064696A1 (en) * 2007-11-14 2009-05-22 The Regents Of The University Of California Sterol-modified amphiphilic lipids
US20090221953A1 (en) * 2008-02-26 2009-09-03 Kazuaki Kajimoto Composition comprising protein-liposome complex for iontophoresis
US20120231066A1 (en) * 2011-01-24 2012-09-13 Henry John Smith Multi-drug liposomes to treat tumors
WO2014028777A2 (en) * 2012-08-16 2014-02-20 Ipierian, Inc. Methods of treating a tauopathy

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05505680A (en) * 1991-01-11 1993-08-19 コーブ　ラボラトリーズ　インコーポレイテッド Methods for Assaying Circulating Antibody Types Using Dried or Lyophilized Cells or Cell-Like Materials
US6156337A (en) * 1994-07-08 2000-12-05 Opperbas Holding B.V. Method for high loading of vesicles with biopolymeric substances
JP2004525916A (en) 2001-03-08 2004-08-26 ターゲサム・インコーポレーテッド Stabilized therapeutic and imaging agents
ATE476964T1 (en) * 2003-06-04 2010-08-15 Univ Georgetown METHOD FOR IMPROVING THE STABILITY AND SHELF LIFE OF LIPOSOME COMPLEXES
EP1663171B9 (en) 2003-08-26 2009-08-19 SmithKline Beecham Corporation Heterofunctional copolymers of glycerol and polyethylene glycol, their conjugates and compositions
EP1675614A2 (en) 2003-10-11 2006-07-05 Inex Pharmaceuticals Corp. Methods and compositions for enhancing innate immunity and antibody dependent cellular cytotoxicity
WO2006037229A1 (en) * 2004-10-06 2006-04-13 Bc Cancer Agency Formulation of multivalent antibody constructs and use of same for cancer therapy
AU2005302255A1 (en) * 2004-10-28 2006-05-11 Alza Corporation Lyophilized liposome formulations and method
MX2007013200A (en) 2005-04-22 2008-03-24 Johnson & Johnson Immunoliposome composition for targeting to a her2 cell receptor.
JP2006316040A (en) 2005-05-13 2006-11-24 Genentech Inc Herceptin(r) adjuvant treatment
EP2480208A1 (en) 2009-09-23 2012-08-01 Indu Javeri Methods for the preparation of liposomes
CN102100916A (en) * 2009-12-22 2011-06-22 上海抗体药物国家工程研究中心有限公司 Freeze-drying liposome and preparation method and application thereof
DK2729127T3 (en) * 2011-07-04 2018-08-06 Statens Seruminstitut METHODS FOR LIPOSOMES PREPARATION
US20150216998A1 (en) 2012-01-01 2015-08-06 Ramot At Tel-Aviv University Ltd. Endo180-targeted particles for selective delivery of therapeutic and diagnostic agents
CA2806896C (en) 2012-09-19 2021-06-15 Georgetown University Targeted liposomes prepared by ethanol injection

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
US20080279927A1 (en) * 2002-12-31 2008-11-13 Bharat Serums & Vaccines Ltd Non-Pegylated Long-Circulating Liposomes
WO2006099169A2 (en) * 2005-03-10 2006-09-21 Mebiopharm Co., Ltd. Novel liposome compositions
WO2007127272A2 (en) * 2006-04-24 2007-11-08 The Cbr Institute For Biomedical Research Method of producing immunoliposomes and compositions thereof
WO2009038779A2 (en) * 2007-09-19 2009-03-26 University Of Tennessee Research Foundation Methods and compositions for inhibiting undesirable cellular proliferation by targeted liposome delivery of active agents
WO2009064696A1 (en) * 2007-11-14 2009-05-22 The Regents Of The University Of California Sterol-modified amphiphilic lipids
US20090221953A1 (en) * 2008-02-26 2009-09-03 Kazuaki Kajimoto Composition comprising protein-liposome complex for iontophoresis
US20120231066A1 (en) * 2011-01-24 2012-09-13 Henry John Smith Multi-drug liposomes to treat tumors
WO2014028777A2 (en) * 2012-08-16 2014-02-20 Ipierian, Inc. Methods of treating a tauopathy

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LOUGHREY H ET AL: "A non-covalent method of attaching antibodies to liposomes", BIOCHIMICA ET BIOPHYSICA ACTA (BBA) - BIOMEMBRANES, ELSEVIER, AMSTERDAM, NL, vol. 901, no. 1, 10 July 1987 (1987-07-10), pages 157 - 160, XP023363768, ISSN: 0005-2736, [retrieved on 19870710], DOI: 10.1016/0005-2736(87)90267-7 *
See also references of WO2018026794A1 *

Also Published As

Publication number Publication date
EP3493790A1 (en) 2019-06-12
CA3032810A1 (en) 2018-02-08
JP2019526619A (en) 2019-09-19
CN109562067A (en) 2019-04-02
JP7019201B2 (en) 2022-02-15
WO2018026794A1 (en) 2018-02-08

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