EP3490618A1 - Two-part cleaning and/or disinfecting system - Google Patents
Two-part cleaning and/or disinfecting systemInfo
- Publication number
- EP3490618A1 EP3490618A1 EP17765213.8A EP17765213A EP3490618A1 EP 3490618 A1 EP3490618 A1 EP 3490618A1 EP 17765213 A EP17765213 A EP 17765213A EP 3490618 A1 EP3490618 A1 EP 3490618A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- disinfection system
- detergent solution
- cleaning
- disinfecting
- hard surface
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000004140 cleaning Methods 0.000 title claims abstract description 35
- 230000000249 desinfective effect Effects 0.000 title claims abstract description 32
- 239000003599 detergent Substances 0.000 claims abstract description 53
- 239000000203 mixture Substances 0.000 claims abstract description 46
- 239000007793 ph indicator Substances 0.000 claims abstract description 15
- 238000006243 chemical reaction Methods 0.000 claims abstract description 7
- 239000007788 liquid Substances 0.000 claims abstract description 7
- 150000004967 organic peroxy acids Chemical class 0.000 claims abstract description 3
- 238000004659 sterilization and disinfection Methods 0.000 claims description 27
- 239000000645 desinfectant Substances 0.000 claims description 24
- 150000004965 peroxy acids Chemical class 0.000 claims description 16
- KFSLWBXXFJQRDL-UHFFFAOYSA-N Peracetic acid Chemical compound CC(=O)OO KFSLWBXXFJQRDL-UHFFFAOYSA-N 0.000 claims description 12
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical group OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 7
- -1 aliphatic peracids Chemical class 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 239000000523 sample Substances 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 239000000835 fiber Substances 0.000 claims description 5
- 239000004088 foaming agent Substances 0.000 claims description 5
- 229920000297 Rayon Polymers 0.000 claims description 4
- 230000003113 alkalizing effect Effects 0.000 claims description 4
- 238000001631 haemodialysis Methods 0.000 claims description 4
- 230000000322 hemodialysis Effects 0.000 claims description 4
- 150000001412 amines Chemical group 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 239000005080 phosphorescent agent Substances 0.000 claims description 3
- 239000004698 Polyethylene Substances 0.000 claims description 2
- 239000004743 Polypropylene Substances 0.000 claims description 2
- 239000003513 alkali Substances 0.000 claims description 2
- 150000001414 amino alcohols Chemical class 0.000 claims description 2
- 150000004649 carbonic acid derivatives Chemical class 0.000 claims description 2
- 229920000728 polyester Polymers 0.000 claims description 2
- 229920000573 polyethylene Polymers 0.000 claims description 2
- 229920001155 polypropylene Polymers 0.000 claims description 2
- 229920002994 synthetic fiber Polymers 0.000 claims description 2
- 239000012209 synthetic fiber Substances 0.000 claims description 2
- 239000000243 solution Substances 0.000 description 41
- 239000006260 foam Substances 0.000 description 9
- 229920000515 polycarbonate Polymers 0.000 description 7
- 239000004417 polycarbonate Substances 0.000 description 7
- 238000005336 cracking Methods 0.000 description 6
- 239000004094 surface-active agent Substances 0.000 description 5
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 4
- 150000002191 fatty alcohols Chemical class 0.000 description 4
- CEQFOVLGLXCDCX-WUKNDPDISA-N methyl red Chemical compound C1=CC(N(C)C)=CC=C1\N=N\C1=CC=CC=C1C(O)=O CEQFOVLGLXCDCX-WUKNDPDISA-N 0.000 description 4
- PORQOHRXAJJKGK-UHFFFAOYSA-N 4,5-dichloro-2-n-octyl-3(2H)-isothiazolone Chemical compound CCCCCCCCN1SC(Cl)=C(Cl)C1=O PORQOHRXAJJKGK-UHFFFAOYSA-N 0.000 description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- DHNRXBZYEKSXIM-UHFFFAOYSA-N chloromethylisothiazolinone Chemical compound CN1SC(Cl)=CC1=O DHNRXBZYEKSXIM-UHFFFAOYSA-N 0.000 description 3
- 150000007524 organic acids Chemical class 0.000 description 3
- UKLNMMHNWFDKNT-UHFFFAOYSA-M sodium chlorite Chemical compound [Na+].[O-]Cl=O UKLNMMHNWFDKNT-UHFFFAOYSA-M 0.000 description 3
- 229960002218 sodium chlorite Drugs 0.000 description 3
- 229940100555 2-methyl-4-isothiazolin-3-one Drugs 0.000 description 2
- GCZLBHOAHLBGEA-UHFFFAOYSA-N 3-butyl-1,2-benzothiazole 1-oxide Chemical compound C1=CC=C2C(CCCC)=NS(=O)C2=C1 GCZLBHOAHLBGEA-UHFFFAOYSA-N 0.000 description 2
- 235000014469 Bacillus subtilis Nutrition 0.000 description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 2
- 125000000217 alkyl group Chemical group 0.000 description 2
- 239000002280 amphoteric surfactant Substances 0.000 description 2
- 230000000845 anti-microbial effect Effects 0.000 description 2
- DMSMPAJRVJJAGA-UHFFFAOYSA-N benzo[d]isothiazol-3-one Chemical compound C1=CC=C2C(=O)NSC2=C1 DMSMPAJRVJJAGA-UHFFFAOYSA-N 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 230000000295 complement effect Effects 0.000 description 2
- OSVXSBDYLRYLIG-UHFFFAOYSA-N dioxidochlorine(.) Chemical compound O=Cl=O OSVXSBDYLRYLIG-UHFFFAOYSA-N 0.000 description 2
- WJJMNDUMQPNECX-UHFFFAOYSA-N dipicolinic acid Chemical compound OC(=O)C1=CC=CC(C(O)=O)=N1 WJJMNDUMQPNECX-UHFFFAOYSA-N 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- SYELZBGXAIXKHU-UHFFFAOYSA-N dodecyldimethylamine N-oxide Chemical compound CCCCCCCCCCCC[N+](C)(C)[O-] SYELZBGXAIXKHU-UHFFFAOYSA-N 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 239000003752 hydrotrope Substances 0.000 description 2
- MGIYRDNGCNKGJU-UHFFFAOYSA-N isothiazolinone Chemical compound O=C1C=CSN1 MGIYRDNGCNKGJU-UHFFFAOYSA-N 0.000 description 2
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 description 2
- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 description 2
- 239000002736 nonionic surfactant Substances 0.000 description 2
- KJFMBFZCATUALV-UHFFFAOYSA-N phenolphthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2C(=O)O1 KJFMBFZCATUALV-UHFFFAOYSA-N 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- QUCDWLYKDRVKMI-UHFFFAOYSA-M sodium;3,4-dimethylbenzenesulfonate Chemical compound [Na+].CC1=CC=C(S([O-])(=O)=O)C=C1C QUCDWLYKDRVKMI-UHFFFAOYSA-M 0.000 description 2
- 230000003330 sporicidal effect Effects 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- JSQZLEYFOOSZPU-UHFFFAOYSA-N 1-[(3-carbamimidoylphenyl)methyl]-n-[(3,5-dimethylphenyl)methyl]-4-methylindole-2-carboxamide Chemical compound CC1=CC(C)=CC(CNC(=O)C=2N(C3=CC=CC(C)=C3C=2)CC=2C=C(C=CC=2)C(N)=N)=C1 JSQZLEYFOOSZPU-UHFFFAOYSA-N 0.000 description 1
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 description 1
- 229940058020 2-amino-2-methyl-1-propanol Drugs 0.000 description 1
- QTDIEDOANJISNP-UHFFFAOYSA-N 2-dodecoxyethyl hydrogen sulfate Chemical compound CCCCCCCCCCCCOCCOS(O)(=O)=O QTDIEDOANJISNP-UHFFFAOYSA-N 0.000 description 1
- JCYPECIVGRXBMO-UHFFFAOYSA-N 4-(dimethylamino)azobenzene Chemical compound C1=CC(N(C)C)=CC=C1N=NC1=CC=CC=C1 JCYPECIVGRXBMO-UHFFFAOYSA-N 0.000 description 1
- ZPLCXHWYPWVJDL-UHFFFAOYSA-N 4-[(4-hydroxyphenyl)methyl]-1,3-oxazolidin-2-one Chemical compound C1=CC(O)=CC=C1CC1NC(=O)OC1 ZPLCXHWYPWVJDL-UHFFFAOYSA-N 0.000 description 1
- YGUMVDWOQQJBGA-VAWYXSNFSA-N 5-[(4-anilino-6-morpholin-4-yl-1,3,5-triazin-2-yl)amino]-2-[(e)-2-[4-[(4-anilino-6-morpholin-4-yl-1,3,5-triazin-2-yl)amino]-2-sulfophenyl]ethenyl]benzenesulfonic acid Chemical compound C=1C=C(\C=C\C=2C(=CC(NC=3N=C(N=C(NC=4C=CC=CC=4)N=3)N3CCOCC3)=CC=2)S(O)(=O)=O)C(S(=O)(=O)O)=CC=1NC(N=C(N=1)N2CCOCC2)=NC=1NC1=CC=CC=C1 YGUMVDWOQQJBGA-VAWYXSNFSA-N 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- FRPHFZCDPYBUAU-UHFFFAOYSA-N Bromocresolgreen Chemical compound CC1=C(Br)C(O)=C(Br)C=C1C1(C=2C(=C(Br)C(O)=C(Br)C=2)C)C2=CC=CC=C2S(=O)(=O)O1 FRPHFZCDPYBUAU-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 239000004155 Chlorine dioxide Substances 0.000 description 1
- JGFDZZLUDWMUQH-UHFFFAOYSA-N Didecyldimethylammonium Chemical class CCCCCCCCCC[N+](C)(C)CCCCCCCCCC JGFDZZLUDWMUQH-UHFFFAOYSA-N 0.000 description 1
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical compound [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 description 1
- ATJXMQHAMYVHRX-CPCISQLKSA-N Ellagic acid Natural products OC1=C(O)[C@H]2OC(=O)c3cc(O)c(O)c4OC(=O)C(=C1)[C@H]2c34 ATJXMQHAMYVHRX-CPCISQLKSA-N 0.000 description 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 description 1
- BELBBZDIHDAJOR-UHFFFAOYSA-N Phenolsulfonephthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2S(=O)(=O)O1 BELBBZDIHDAJOR-UHFFFAOYSA-N 0.000 description 1
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical class OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- CBTVGIZVANVGBH-UHFFFAOYSA-N aminomethyl propanol Chemical compound CC(C)(N)CO CBTVGIZVANVGBH-UHFFFAOYSA-N 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 210000004666 bacterial spore Anatomy 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- UDSAIICHUKSCKT-UHFFFAOYSA-N bromophenol blue Chemical compound C1=C(Br)C(O)=C(Br)C=C1C1(C=2C=C(Br)C(O)=C(Br)C=2)C2=CC=CC=C2S(=O)(=O)O1 UDSAIICHUKSCKT-UHFFFAOYSA-N 0.000 description 1
- 235000019398 chlorine dioxide Nutrition 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- OBRMNDMBJQTZHV-UHFFFAOYSA-N cresol red Chemical compound C1=C(O)C(C)=CC(C2(C3=CC=CC=C3S(=O)(=O)O2)C=2C=C(C)C(O)=CC=2)=C1 OBRMNDMBJQTZHV-UHFFFAOYSA-N 0.000 description 1
- 238000010908 decantation Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- YRIUSKIDOIARQF-UHFFFAOYSA-N dodecyl benzenesulfonate Chemical compound CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 YRIUSKIDOIARQF-UHFFFAOYSA-N 0.000 description 1
- MOTZDAYCYVMXPC-UHFFFAOYSA-N dodecyl hydrogen sulfate Chemical compound CCCCCCCCCCCCOS(O)(=O)=O MOTZDAYCYVMXPC-UHFFFAOYSA-N 0.000 description 1
- JRBPAEWTRLWTQC-UHFFFAOYSA-N dodecylamine Chemical compound CCCCCCCCCCCCN JRBPAEWTRLWTQC-UHFFFAOYSA-N 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- JYINMLPNDRBKKZ-UHFFFAOYSA-N hydroperoxybenzene Chemical compound OOC1=CC=CC=C1 JYINMLPNDRBKKZ-UHFFFAOYSA-N 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 238000005470 impregnation Methods 0.000 description 1
- 238000010952 in-situ formation Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- STZCRXQWRGQSJD-GEEYTBSJSA-M methyl orange Chemical compound [Na+].C1=CC(N(C)C)=CC=C1\N=N\C1=CC=C(S([O-])(=O)=O)C=C1 STZCRXQWRGQSJD-GEEYTBSJSA-M 0.000 description 1
- 229940012189 methyl orange Drugs 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- NYNKJVPRTLBJNQ-UHFFFAOYSA-N n'-(3-aminopropyl)-n'-dodecylpropane-1,3-diamine Chemical compound CCCCCCCCCCCCN(CCCN)CCCN NYNKJVPRTLBJNQ-UHFFFAOYSA-N 0.000 description 1
- JPMIIZHYYWMHDT-UHFFFAOYSA-N octhilinone Chemical compound CCCCCCCCN1SC=CC1=O JPMIIZHYYWMHDT-UHFFFAOYSA-N 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 229960003531 phenolsulfonphthalein Drugs 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000001235 sensitizing effect Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- ZHFPEICFUVWJIS-UHFFFAOYSA-M sodium 2-hydroxy-5-[(3-nitrophenyl)diazenyl]benzoate Chemical compound [Na+].Oc1ccc(cc1C([O-])=O)N=Nc1cccc(c1)[N+]([O-])=O ZHFPEICFUVWJIS-UHFFFAOYSA-M 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 229940048842 sodium xylenesulfonate Drugs 0.000 description 1
- KVCGISUBCHHTDD-UHFFFAOYSA-M sodium;4-methylbenzenesulfonate Chemical compound [Na+].CC1=CC=C(S([O-])(=O)=O)C=C1 KVCGISUBCHHTDD-UHFFFAOYSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000004381 surface treatment Methods 0.000 description 1
- PRZSXZWFJHEZBJ-UHFFFAOYSA-N thymol blue Chemical compound C1=C(O)C(C(C)C)=CC(C2(C3=CC=CC=C3S(=O)(=O)O2)C=2C(=CC(O)=C(C(C)C)C=2)C)=C1C PRZSXZWFJHEZBJ-UHFFFAOYSA-N 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/24—Medical instruments, e.g. endoscopes, catheters, sharps
Definitions
- the present invention relates to a two-part cleaning and disinfection system. This system finds particular application in the field of cleaning and disinfection of medical equipment and instruments, including endoscopes.
- a cleaning wipe impregnated with a detergent solution For both cleaning and disinfecting, it is now necessary to use different types of wipes: first a cleaning wipe impregnated with a detergent solution, then at least one disinfectant wipe.
- a cleaning wipe impregnated with a detergent solution For example marketed by the company Tristel (Snailwell, Cambridgeshire, United Kingdom) under the name "Tristel Trio ® Wipes System”.
- Tristel Trio ® Wipes System This system consists of a detergent wipe, a sporicidal wipe and a rinsing cloth impregnated with demineralized water. Each wipe is supplied in a unit bag.
- Tristel The cleaning and disinfection system offered by Tristel has the disadvantage that it requires two different wipes, one for cleaning and one for disinfection, which can be a source of error. Indeed, once unpacked it is not possible to instigate with the naked eye the detergent wipe of the disinfectant wipe.
- the packaging of the Tristel Trio ® system is complex and unecological due to the principle of the unit bag. There is therefore a need for a disinfection and cleaning system for cleaning and disinfecting medical equipment and instruments that is easier to use than the Tristel Trio ® system .
- An object of the invention is therefore a two-part cleaning and disinfection system comprising:
- a first part comprising at least one non-woven support of a detergent solution
- a second part comprising a container containing a disinfectant liquid composition
- the detergent solution comprises a color pH indicator
- the composition disinfectant comprises at least one peracid which produces a colorimetric reaction with the pH indicator when it is brought into contact with the nonwoven support.
- This system has the advantage that the non-woven support of a detergent solution is versatile. It can on one side be used as is for cleaning and on the other side it serves as a substrate for the disinfectant composition.
- the disinfectant composition is applied to the nonwoven support impregnated with a detergent solution and is uniformly penetrated throughout the support.
- the detergent solution whose nonwoven support is impregnated comprises a color pH indicator makes it possible to ensure that the peracetic acid is distributed homogeneously over the entire support by the appearance of an uniform coloration. .
- the disinfecting power is directly provided by the organic peracid of the disinfecting composition and not the result of a chemical reaction between a first reagent, an organic acid, present in the nonwoven support and a second reagent, sodium chlorite, brought in the form of foam. This has the advantage of greater reproducibility of the disinfecting power since it is not subject to the hazards of a chemical reaction.
- the peracid is advantageously chosen from aliphatic peracids, in particular from C2 to C4.
- the disinfectant composition comprises at least peracetic acid.
- the peracid, in particular peracetic acid may be used alone or in admixture with another peracid.
- the peracid content of the disinfecting composition is advantageously from 0.1 to 2% by weight, preferably from 0.4 to 1.6%, by weight relative to the total weight of the disinfecting composition.
- the disinfectant composition also comprises hydrogen peroxide, preferably in an amount of 3 to 25%, preferably 3 to 15% by weight relative to the total weight of the composition.
- the disinfectant composition is formulated in liquid form. It may be contained in any container suitable for the distribution of this type of product.
- suitable containers include spray bottles, especially trigger bottles, dosing pump bottles, bottles with foam dispensers, flasks with flap cap and drop-edge bottles.
- the disinfectant composition can be applied in the form of foam on the nonwoven support with the aid of a suitable dispensing container.
- a suitable dispensing container Such containers are well known to those skilled in the art and include in particular the bottles with foam dispenser.
- Applying the liquid composition in the form of foam facilitates the absorption of the disinfectant composition and makes it easy to control the amount of peracid applied to the nonwoven support because the foam is visible before it enters the support .
- the use of a foam limits the odor of the peracid, in particular peracetic acid.
- the foaming agents being well known to those skilled in the art, the latter will know how to choose a suitable one.
- Non-limiting examples of foaming agents include amine oxide surfactants, such as dimethyl laurylamine oxide, lauryl sulphate anionic surfactants, lauryl ether sulphate, dodecyl benzene sulphonate or nonionic surfactants such as alkyl polyglucosides, or fatty alcohols. alkoxylates, especially ethoxylated fatty alcohols.
- the liquid disinfectant composition is non-foaming and can therefore be applied, for example, by spraying the nonwoven support.
- the disinfectant composition is preferably an aqueous composition. It may further comprise additives such as stabilizing agents such as dipicolinic acid and phosphonates.
- the nonwoven support impregnated with the detergent solution is advantageously contained in a container that is airtight and watertight in order to prevent it from drying out. It may for example be a resealable container that can contain a plurality of wipes or a unitary package containing a single wipe, such as a sachet.
- reclosable containers include resealable bags, boxes with resealable lid and / or provided with a resealable dispensing orifice, buckets with reclosable lid and / or provided with a resealable dispensing orifice.
- the nonwoven support is composed of a plurality of wipes.
- This plurality of detachable wipes may for example be in the form of a roller.
- This roller can in particular be provided in a closed bucket provided with a resealable dispensing orifice.
- the user can detach one or more wipes according to his needs and then close the bucket for later use of the remaining wipes.
- the nonwoven support may be of natural and / or synthetic fibers.
- the fibers are chosen from viscose, polyester, polyethylene and polypropylene fibers, and mixtures thereof.
- Particularly interesting results have been obtained with 100% viscose wipes. Indeed, this type of wipe allows a homogeneous and stable distribution of the detergent solution and thus avoids the phenomenon of decantation of the detergent solution in time observed with other types of wipes. This phenomenon is particularly pronounced when the nonwoven support is a roll of wipes positioned vertically in a container such as a bucket. In this case, the detergent solution accumulates in the bottom of the wipes which decreases cleaning performance of wipes.
- Other suitable fibers that can be used in the context of the invention are well known to those skilled in the art.
- the impregnation rate of the wipes with the detergent solution is advantageously from 100 to 500% by weight, preferably from 200 to 400% by weight and more preferably from approximately 300% by weight relative to the dry weight of the wipes.
- the detergent solution with which the nonwoven support is impregnated is preferably an aqueous solution comprising a mild alkalizing agent.
- This mild alkaline agent is preferably selected from aminoalcohols, alkali or alkaline earth carbonates and mixtures thereof.
- the aminoalcohol is chosen from monoethanolamine, triethanolamine and 2-amino-2-methyl-1-propanol. More preferably, it is triethanolamine.
- the mild alkalizing agent is advantageously contained in the detergent solution in an amount of from 0.1 to 2%, preferably from 0.2 to 1% and more preferably from 0.25 to 0.6%, for example from about 0.3% by weight based on the total weight of the solution.
- the detergent solution comprises tritethanolamine, preferably in an amount of 0.25 to 0.6%, for example about 0.3% by weight based on the total weight of the solution.
- triethanolamine especially in the amounts indicated, is particularly advantageous when the cleaning and disinfection system according to the invention is used for the surface treatment of polycarbonate, a polymer commonly used in the field.
- Polycarbonate is indeed ubiquitous in health facilities, it is particularly a constituent material of the fairing of medical devices such as transesophageal probes, hemodialysis generators, ultrasonic probes, electronic thermometers etc.
- Polycarbonate is a ductile and fragile polymer with a high sensitivity to contact with chemicals. This sensitivity is characterized by a phenomenon of cracking (English: stress cracking) with the consequence, in case of repeated application of a detergent or a disinfectant not compatible with the polycarbonate, a depolymerization of the polycarbonate. The latter usually has a corollary fragility and then breaks the medical device.
- the detergent solutions according to the invention containing triethanolamine minimize or even avoid the occurrence of cracking phenomenon (stress cracking) in the polycarbonate after repeated applications.
- the pH of the detergent solution is preferably slightly alkaline, preferably 7.5 to 8.5, more preferably about 8.
- the detergent solution may also include one or more surfactants.
- These surfactants are preferably chosen from nonionic, amphoteric surfactants and mixtures thereof.
- Nonlimiting examples of nonionic surfactants include alkylpolyglucosides, alkylpolypentosides, amine oxides, polyglycosides, glucamides, polyalkoxylated fatty alcohols, in particular polyethoxylated fatty alcohols, and ethoxylated fatty acid esters, oxides of amino being preferred.
- Non-limiting examples of amphoteric surfactants include cocamidopropyl betaines.
- the surfactant or surfactants are advantageously contained in the detergent solution in an amount of from 0.001 to 2%, preferably from 0.01 to 0.1% and even more preferably from 0.025 to 0.05% by weight relative to the total weight of the composition.
- the color pH indicator included in the detergent solution may be chosen from all those which give rise to a colorimetric reaction in contact with the peracid of the disinfecting composition.
- Nonlimiting examples of pH indicator that may be used in the context of the present invention include phenol red, bromothymol blue, thymol blue, methyl yellow, methyl orange, bromophenol blue, bromcresol green, methyl red, phenolphthalein, alizarin yellow and cresol red.
- the pH indicator is methyl red.
- the pH indicator is advantageously contained in the detergent solution in an amount of 3 to 15 ppm, preferably 5 to 10 ppm and more preferably still 7 to 8 ppm by weight relative to the total weight of the composition.
- the detergent solution also comprises a preserving agent such as a didecyldimethylammonium salt, bis (aminopropyl) laurylamine, an isothiazolinone, benzyl alcohol, a phenoxy alcohol or sodium benzoate.
- the isothiazolinone is advantageously chosen from methylisothiazolinone (MIT, MI), chloromethylisothiazolinone (CMIT, CMI, MCI), benzisothiazolinone (BIT), octylisothiazolinone (OIT, 01), dichlorooctylisothiazolinone (DCOIT, DCOI) and butylbenzisothiazolinone (BBIT) and mixtures thereof, preferably it is methylisothiazolinone.
- the preserving agent is advantageously contained in the detergent solution in an amount of from 0.0001 to 0.1%, preferably from 0.0 to 0.05% and more preferably from 0.02 to 0.03% by weight. relative to the total weight of the composition.
- the detergent solution according to the invention may further comprise one or more excipient (s) chosen from the group consisting of emulsifiers, hydrotropes and polyol-type third-solvents such as glycerol.
- excipient chosen from the group consisting of emulsifiers, hydrotropes and polyol-type third-solvents such as glycerol.
- hydrotrope refers to, but is not limited to, sodium para-toluenesulfonate and sodium xylenesulfonate.
- the detergent solution further comprises one or more phosphorescent agents such as disodium 2,2 '- ([1,1'-biphenyl] -4,4-diyldivinylene) bis (benzenesulphonate) ( Tinopal® CBS sold by BASF (Ludwigshafen, Germany)) or optical brighteners such as Sera White PN commercialized by Dystar.
- phosphorescent agents such as disodium 2,2 '- ([1,1'-biphenyl] -4,4-diyldivinylene) bis (benzenesulphonate) ( Tinopal® CBS sold by BASF (Ludwigshafen, Germany)) or optical brighteners such as Sera White PN commercialized by Dystar.
- a phosphorescent agent makes it possible to visualize under UV light the surfaces treated by the nonwoven support. This makes it possible to verify the homogeneity of the treatment of the medical device by the nonwoven support impregnated with the detergent solution.
- the two-part cleaning and disinfecting system according to the invention is particularly advantageous for cleaning and disinfecting objects having a hard surface, such as medical instruments and devices as well as working surfaces, in that it makes it possible to use a single type of non-woven support impregnated with a detergent solution for two distinct and complementary applications: as such to clean the object and after application of the disinfecting composition to disinfect the 'object.
- Medical instruments and devices within the meaning of the present invention include endoscopes without an internal channel such as nasofibroscopes and transoesophageal, hemodialysis generators, ultrasonic probes and electronic thermometers.
- a second object of the invention is the use of the two-part wipe system described above for cleaning and / or disinfecting objects having a hard surface, such as medical instruments and devices and surfaces. working.
- the invention also relates to a method for cleaning and disinfecting an object having a hard surface, such as medical instruments and devices and work surfaces, comprising the following steps: a) Providing a cleaning and disinfection system two parts as defined above, comprising a first part comprising at least one nonwoven support impregnated with a detergent solution comprising a color pH indicator, and a second part comprising a container containing a disinfecting composition comprising at least one peracid;
- step c) wiping the hard surface of said object previously wiped with the first nonwoven support with the nonwoven disinfectant support prepared in step c);
- the support changes color because of the colorimetric reaction between the pH indicator of the detergent solution and the peracid of the disinfecting composition. For example, when the pH indicator is methyl red, the nonwoven support impregnated with the solution detergent alone is yellow and becomes pink when applying the disinfectant composition containing the peracid.
- the application of the disinfecting composition comprising at least one peracid gives the nonwoven support a broad-spectrum biocidal action against bacteria, yeasts, molds, mycobacteria, naked and enveloped viruses and bacterial spores.
- the present invention provides a two part cleaning and disinfection system that is easy to use and effective. In particular, it avoids the risks associated with the in situ formation of chemicals and thus minimizes the risk of insufficient disinfecting power.
- the fact of starting from a nonwoven substrate impregnated with a detergent solution makes the system particularly versatile since only one type of nonwoven support can be used for two distinct and complementary applications. More particularly, the nonwoven support impregnated with the detergent solution may be used alone for cleaning an object having a hard surface without this cleaning being followed by a disinfection step.
- Example 1 Preparation of the detergent compositions
- the detergent solutions SI to S8 (pH 8), the formulas of which are given in Table 1, were prepared by adding a premix at a level of 1.5% by weight to the respective detergent solution.
- This premix consists of 97.95% by weight of demineralised water, 0.05% by weight of methyl red and 2% by weight of triethanolamine (99%).
- alkyls (C8- 0, 1 - - 0, 1 - 0,1 - - C16) 53%
- the stress cracking tests were carried out by immersion of 1.5 cm x 10 cm polycarbonate specimens with a thickness of 1 mm (to be verified). The specimens are placed under stress in a rigid metal frame with a width of 7.5 cm. This frame is then immersed in the detergent solution in a cycle of 30 min at room temperature followed by drying for 3 hours at room temperature.
- the antimicrobial activity of the disinfecting wipes was determined according to the protocol of the European standard NF EN 16615 (2015-05-15).
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Detergent Compositions (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
Description
Claims
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1657286A FR3054446B1 (en) | 2016-07-28 | 2016-07-28 | SYSTEM FOR CLEANING AND / OR DISINFECTING INTO TWO PARTS |
PCT/FR2017/052140 WO2018020190A1 (en) | 2016-07-28 | 2017-07-28 | Two-part cleaning and/or disinfecting system |
Publications (1)
Publication Number | Publication Date |
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EP3490618A1 true EP3490618A1 (en) | 2019-06-05 |
Family
ID=56990643
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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EP17765213.8A Withdrawn EP3490618A1 (en) | 2016-07-28 | 2017-07-28 | Two-part cleaning and/or disinfecting system |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP3490618A1 (en) |
FR (1) | FR3054446B1 (en) |
TW (1) | TWI745412B (en) |
WO (1) | WO2018020190A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102022101454A1 (en) * | 2022-01-21 | 2023-07-27 | Schülke & Mayr GmbH | Disinfection system with a sheet made of a thermobond non-woven fabric comprising polypropylene |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0411304D0 (en) | 2004-05-21 | 2004-06-23 | Fellows Adrian N | An antimicrobial composition |
US7807118B2 (en) * | 2004-09-07 | 2010-10-05 | Tristel Plc | Decontamination system |
WO2006052369A1 (en) * | 2004-11-05 | 2006-05-18 | Virox Technologies Inc. | Cleaning and disinfectant compositions |
UY31056A1 (en) * | 2007-05-01 | 2008-10-31 | Alcon Res Ltd | N-HALOGENATED AMINOCIDE FROMULATIONS AND CLEANING AND DISINFECTION METHODS |
GB201312189D0 (en) * | 2013-07-08 | 2013-08-21 | Xeros Ltd | New cleaning formulation and method |
GB2518239A (en) * | 2013-09-17 | 2015-03-18 | Tristel Plc | Decontamination System |
DE202014103637U1 (en) * | 2014-08-05 | 2014-08-18 | Thomas Wilbert | Cleaning system and disinfecting cloth with a cleaning system |
-
2016
- 2016-07-28 FR FR1657286A patent/FR3054446B1/en active Active
-
2017
- 2017-07-28 EP EP17765213.8A patent/EP3490618A1/en not_active Withdrawn
- 2017-07-28 TW TW106125383A patent/TWI745412B/en not_active IP Right Cessation
- 2017-07-28 WO PCT/FR2017/052140 patent/WO2018020190A1/en unknown
Also Published As
Publication number | Publication date |
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TWI745412B (en) | 2021-11-11 |
FR3054446A1 (en) | 2018-02-02 |
WO2018020190A1 (en) | 2018-02-01 |
TW201803601A (en) | 2018-02-01 |
FR3054446B1 (en) | 2018-08-31 |
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