EP3405567A4 - Compositions and methods for immune cell modulation in adoptive immunotherapies - Google Patents

Compositions and methods for immune cell modulation in adoptive immunotherapies Download PDF

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Publication number
EP3405567A4
EP3405567A4 EP17742046.0A EP17742046A EP3405567A4 EP 3405567 A4 EP3405567 A4 EP 3405567A4 EP 17742046 A EP17742046 A EP 17742046A EP 3405567 A4 EP3405567 A4 EP 3405567A4
Authority
EP
European Patent Office
Prior art keywords
compositions
methods
immune cell
cell modulation
adoptive immunotherapies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP17742046.0A
Other languages
German (de)
French (fr)
Other versions
EP3405567A1 (en
Inventor
Jonathan Rosen
Betsy REZNER
Bahram Valamehr
Ryan BJORDAHL
Eigen Peralta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fate Therapeutics Inc
Original Assignee
Fate Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fate Therapeutics Inc filed Critical Fate Therapeutics Inc
Publication of EP3405567A1 publication Critical patent/EP3405567A1/en
Publication of EP3405567A4 publication Critical patent/EP3405567A4/en
Pending legal-status Critical Current

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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
EP17742046.0A 2016-01-20 2017-01-20 Compositions and methods for immune cell modulation in adoptive immunotherapies Pending EP3405567A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662281064P 2016-01-20 2016-01-20
US201662336339P 2016-05-13 2016-05-13
PCT/US2017/014408 WO2017127729A1 (en) 2016-01-20 2017-01-20 Compositions and methods for immune cell modulation in adoptive immunotherapies

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Publication Number Publication Date
EP3405567A1 EP3405567A1 (en) 2018-11-28
EP3405567A4 true EP3405567A4 (en) 2019-10-30

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EP17742046.0A Pending EP3405567A4 (en) 2016-01-20 2017-01-20 Compositions and methods for immune cell modulation in adoptive immunotherapies

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US (2) US11096964B2 (en)
EP (1) EP3405567A4 (en)
JP (2) JP2019502722A (en)
KR (1) KR20180096707A (en)
CN (2) CN108473959B (en)
AU (3) AU2017210031C1 (en)
CA (1) CA3010236A1 (en)
SG (1) SG11201805186VA (en)
WO (1) WO2017127729A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9511092B2 (en) 2013-01-28 2016-12-06 St. Jude Children's Research Hospital, Inc. Chimeric receptor with NKG2D specificity for use in cell therapy against cancer and infectious disease
EP3143134B1 (en) 2014-05-15 2020-10-28 National University of Singapore Modified natural killer cells and uses thereof
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