EP3350102B1 - Capsules pour les machines à preparation des infusions - Google Patents

Capsules pour les machines à preparation des infusions Download PDF

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Publication number
EP3350102B1
EP3350102B1 EP16767217.9A EP16767217A EP3350102B1 EP 3350102 B1 EP3350102 B1 EP 3350102B1 EP 16767217 A EP16767217 A EP 16767217A EP 3350102 B1 EP3350102 B1 EP 3350102B1
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EP
European Patent Office
Prior art keywords
capsule
stem
insert
cup
frustum
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EP16767217.9A
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German (de)
English (en)
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EP3350102A1 (fr
Inventor
Roberto Stefanoni
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Imper SpA
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Imper SpA
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D85/00—Containers, packaging elements or packages, specially adapted for particular articles or materials
    • B65D85/70—Containers, packaging elements or packages, specially adapted for particular articles or materials for materials not otherwise provided for
    • B65D85/804—Disposable containers or packages with contents which are mixed, infused or dissolved in situ, i.e. without having been previously removed from the package
    • B65D85/8043—Packages adapted to allow liquid to pass through the contents

Definitions

  • the present invention generally relates to the preparation of infused beverages such as coffee, tea, herbal teas and the like, but also to the preparation of beverages based on syrups, liquid and powder concentrates starting from disposable capsules.
  • the invention particularly relates to a disposable single-dose or multi-dose capsule for machines for the dispensing of such beverages.
  • Disposable capsules used in dispensing machines of infused beverages contain a product in a granular or particulate form, for example coffee. It is known that a final beverage is obtained through an "infusion" process that consists in making an infusion liquid supplied under pressure and at elevated temperature, typically water, to cross the capsule containing the granular or particulate product.
  • the infusion liquid coming out from the capsule enriched by the aroma of the granular or particulate product is the desired beverage, which is suitably channeled within a dispensing machine and is dispensed from a dispensing head e.g. into a cup.
  • Known disposable capsules comprise a cup-shaped hollow body, whose open top is provided with a flange on which a cover generally formed of a gas-impermeable film is applied.
  • This film has the function to seal the cavity of the cup-shaped body so as to allow preservation over time of the granular or particulate product contained therein.
  • the capsule is inserted into an infusion chamber of a dispensing machine and subsequently perforated with special perforating members at the bottom of the cup-shaped body and at its top, which is sealed by the gas-impermeable film.
  • the holes thus made allow passage of a flow of infusion liquid through the capsule from one of its ends to the opposite end.
  • the infusion liquid may flow from the bottom of the cup-shaped body towards the top or in the opposite direction.
  • an infused beverage prepared from the capsule is channeled within a dispensing machine and is dispensed from a dispensing head for example into a cup, it is difficult, if not impossible, to avoid taste contamination between different beverages produced one after the other, for example coffee, tea and chocolate, due to the presence of beverage residues after every infusion cycle. Residues typically remain on the perforating members and also inside the channels formed in the dispensing head.
  • capsules for the preparation of infused beverages have been developed which are opened by special opening means enclosed in the capsules exploiting the pressure exerted by the infusion liquid injected inside the capsule.
  • the infused beverage exits the dispensing machine directly from the capsule without interacting with channels, thus avoiding any possible taste contamination among different beverages.
  • the capsule comprises a closed chamber containing a granular or particulate product and means adapted to allow opening of the capsule, wherein opening is obtained due to a relative movement between the opening means and a sealing film of the closed chamber.
  • the relative movement is caused by the pressure increase occurring within the chamber upon injection of the infusion liquid.
  • the opening means comprise a plurality of sharpened elements mounted on a supporting disc housed on the bottom of the capsule below the sealing film of the chamber. Once perforated the film, the infused beverage coming out from the chamber passes through the channels that are formed between the sealing film and the sharpened elements, and is collected on the bottom of the capsule wherein a dispensing opening is formed.
  • the relative movement particularly occurs beyond a pressure threshold, which allows to overcome the mechanical resistance opposed by the opening means, as well as by the sealing film.
  • a problem of this type of capsules is the difficulty to accurately predict the pressure threshold above which opening of the capsule takes place.
  • the internal pressure may in fact depend on the structure of the sealing film, its thickness and the material of which it is made, as well as on the shape and size of the sharpened elements, which are affected by manufacturing tolerances.
  • the variability of the pressure threshold upon which the opening means are activated determines a variability of the flow of infusion liquid through the product contained in the capsule, which results in infused beverages having variable organoleptic properties and that may not appreciated by the users.
  • This capsule comprises a cup-shaped body adapted to receive a measured dose of a granular or particulate product.
  • the cup-shaped body comprises a peripheral wall and a bottom wall having a frusto-conical shape wherein a plurality of through openings are formed.
  • the cup-shaped body is sealed at the top by a cover fixed on a flange of the peripheral wall and at the bottom by a film arranged under the bottom wall, thus exposed to the outside of the cup-shaped body.
  • the capsule described in the international publication WO 2012/121597 A1 is configured to be inserted in an infusion chamber of a machine for the preparation of infused beverages.
  • An injector needle of the machine pierces the cover in correspondence of the cavity of the column-like element, whereby an infusion liquid fills this cavity and flows out into the cavity of the cup-shaped body of the capsule through the indentations formed at the free end of the column-shaped element.
  • the injector needle is associated with a shaped element which, simultaneously with the perforation of the cover, presses the column-like element thus moving it relative to the peripheral wall of the cup-shaped body and causing a deformation of its bottom wall toward the film that seals the cup-shaped body.
  • the cutting elements formed on the bottom wall pierce the film, thus allowing the infused beverage to flow out of the capsule body.
  • a measured dose of a granular or particulate product may be enclosed between an annular filter internally applied to the cup-shaped body close to the bottom wall and a liquid-permeable or perforated film having an annular shape.
  • the liquid-permeable or perforated film is fixed at its inner circumference to the column-shaped element and at its outer circumference to the peripheral wall at an intermediate position in the axial direction between the bottom wall and the cover.
  • This type of capsule allows to obtain opening of the capsule from its inside mechanically, without depending on a predefined pressure threshold exerted by the infusion liquid injected into the product contained in the capsule body.
  • the configuration of the capsule can be improved concerning the arrangement of some of its components/parts and the movement of the column-like element and of the bottom wall in the axial direction.
  • the technical problem posed and solved by the present invention is therefore to provide a disposable capsule for dispensing machines of infused beverages, as well as beverages based on syrups, liquid and powder concentrates, which allows to overcome the drawbacks mentioned above with reference to the prior art.
  • An idea of solution underlying the invention is to realize a capsule provided with opening means housed in a cavity sealed by a top cover film and an bottom inner film, wherein the opening means comprise an insert axially movable between an assembly or packaging position, wherein it rests on the bottom of the capsule cavity with a frusto-conical portion thereof and presses against the top cover film of the capsule with a stem thereof thus deforming the top cover film outwards, and an opening position, wherein by acting on the stem the insert is made to move in the axial direction towards the bottom of the capsule cavity and a plurality of punching elements formed in its frusto-conical portion interfere with the bottom inner film thus tearing it open.
  • opening of the capsule according to the invention occurs mechanically from the inside due to the thrust exerted on the insert stem and to the following deformation of the insert frustum-conical portion on which the punching elements are formed.
  • the capsule according to the invention does not have any pressure threshold of the opening means, thus providing the advantage to ensure constant organoleptic properties of the beverages produced.
  • an insert housed in the capsule body and comprising a stem and a frustum-conical shaped portion leads to capsule having a structure that is remarkably easier than the capsule described in the international publication WO 2012/1215597 A1 .
  • the insert of the capsule of the invention in fact is an independent component that may be manufactured separately from the capsule body by known injection molding processes, which allows to maintain the simple cup shape of the capsule body that may be similarly manufactured by way of injection molding.
  • the monolithic shape of the capsule according to the international publication WO 2012/1215597 A1 comprising a hollow column, i.e. a stem, and a frustum-conical shaped, perforated bottom wall entails the need for a more complex and expensive injection mold.
  • the direct connection between the frustum-conical bottom and the peripheral wall of the capsule body makes the overall structure rather stiff, thus penalizing on the one hand the ability of the bottom wall to be flattened in order to tear open the film sealing the capsule body and, on the other hand, hindering the axial movement of the column, which might be bent laterally.
  • the insert of the capsule according to the invention further comprises a cup-shaped element housed in the capsule in a seat formed close to its flanged edge.
  • the cup-shaped element is provided with a central hole wherein the insert stem is slidably fitted. The central hole allows to position the insert inside the capsule body correctly during assembly or packaging and to guide it so as to facilitate its axial movement towards the opening position.
  • the insert stem and the hole of the cup-shaped element are configured so as to achieve a tight connection in the assembly or packaging condition, whereby the cup-shaped element divides the cavity of the capsule body in two parts, a lower part between the cup-shaped element and the bottom of the capsule body, wherein the granular or particulate product is contained, and an upper part between the cup-shaped element and the cover, wherein a second product, such as milk powder or, more generally, another beverage ingredient, may be advantageously added during assembly or packaging operations.
  • a second product such as milk powder or, more generally, another beverage ingredient
  • the portion of the stem that protrudes from the hole formed in the cup-shaped element in the assembly or packaging position has a reduced cross section area, thus allowing passage of a flow of infusion liquid in the opening position of the capsule, as well as of a possible second product, from the upper part to the lower part of the cavity for the preparation of the beverage.
  • the frustum-conical shaped portion of the insert comprises a plurality of circumferential grooves formed in low relief in its mantle. This feature provides the advantage to ease flattening of the frustum-conical portion and the axial movement of the insert stem, thus facilitating punching of the underlying film sealing the bottom of the capsule body.
  • the capsule with its insert is usable not only for the preparation of beverages in the form of infusion, but also of beverages based on syrups, liquid and powder concentrates thanks to the possibility of arranging in the two parts of the capsule cavity a base product and an ingredient suitable to complete the beverage, a carbon dioxide additive.
  • a disposable capsule according to the invention is generally indicated by reference number 100.
  • the capsule 100 comprises a cup-shaped hollow body 110 adapted to receive a measured dose of a granular or particulate product, for example coffee powder, but also liquid concentrates like syrups.
  • the hollow body 110 comprises a bottom 111, a peripheral wall 112 on whose peripheral edge a flange 113 is formed.
  • the cup-shaped, hollow body 110 is sealed by a cover 120 fixed on the flange 113, for example a film made of a polylaminate material, which has the function to seal the cavity of the hollow body 110 in order to allow preservation over time of the granular or particulate product contained therein.
  • a through opening 114 is formed in the bottom 111 for the dispensing of an infused beverage obtainable from the granular or particulate product, for example an opening having a circular cross-section.
  • the through opening 114 has a funnel shape which facilitates the outflow of an infused beverage, and is reinforced by a plurality of radial ribs 115.
  • the through opening 114 is sealed by a film 130 applied on the bottom 111 inside the hollow body 110 and made e.g. of a polylaminate material, which defines with its peripheral wall 112 and the cover 120 a closed chamber suitable to preserve the granular or particulate product.
  • a film 130 applied on the bottom 111 inside the hollow body 110 and made e.g. of a polylaminate material, which defines with its peripheral wall 112 and the cover 120 a closed chamber suitable to preserve the granular or particulate product.
  • the capsule 100 further comprises an insert 200 housed in its body 110.
  • the insert 200 extends axially from the bottom 111 of the hollow body 110 to the cover 120.
  • the insert 200 comprises a disc-like portion 210 having a frustum-conical shape with a peripheral edge 211 intended to contact the bottom 111 of the body 110 of the capsule 100 and a mantle 212 wherein a plurality of through openings 213 are formed so as to allow a flow of an infusion liquid.
  • the through openings 213 are preferably circular or polygonal, for example square as shown in figure 4 .
  • the frustum-conical portion 210 further comprises one or more punching elements 214 that protrude axially from its concave portion.
  • the punching elements 214 are e.g. in the form of sharpened fins arranged so as to form a star shape whose center coincides with the axis of the frustum-conical portion 210.
  • the insert 200 further comprises a stem 220 that stretches out axially from the top of the frustum-conical, disc-like portion 210, hence from the opposite side with respect to the punching elements 214.
  • the peripheral edge 211 of the frustum-conical, disc-like portion 210 of the insert rests on the bottom 111 of the body 110 of the capsule 100, so that the punching elements 214 face the film 130 that seals the bottom 111.
  • the insert is configured such that, in an assembly or packaging condition of the capsule 100 as that shown in figures 6 and 8 , the punching elements 214 are close to the film 130 without contacting it.
  • the stem 220 stretches out beyond the flanged edge 113, whereby its free end urges the cover providing it with a convex or dome shape.
  • the configuration of the stem 220 is such that, in an assembly or packaging configuration of the capsule, its free end urges the cover 120 and provides it with a convex or dome shape. Moreover, still in an assembly or packaging configuration, the punching elements 214 of the disk-like portion of the insert 200 are close to the film 130 that seals the bottom 111 of the capsule 100 without contacting it.
  • the insert 200 is axially movable between an assembly or packaging position, wherein it presses the cover 120 of the capsule 100 with its stem 220 deforming it outwards, and an opening position, wherein the free end of the stem 220 is advanced in the axial direction and substantially aligned with the flange 113, and the disk-like portion 210 is deformed against the bottom 111, in particular flattened thereon , and the punching elements 214 interfere with the film 130 thus tearing it open.
  • its diameter in the assembly condition i.e. non-deformed, is lower than the diameter of the bottom 111 of the capsule 100, thus defining relative to the peripheral wall a gap suitable to contain the disk-like, frustum-conical portion 210 in the flattened condition, wherein it has a diameter slightly larger than the diameter of the non-deformed condition.
  • a plurality of circumferential grooves 215 are advantageously formed in low relief in its mantle 212.
  • the capsule 100 according to the invention is opened mechanically and in particular independently of the flow of infusion liquid. Opening of the capsule 100 in fact occurs upon closing of the infusion chamber, well before the infusion liquid is injected therein.
  • the insert 200 also comprises a cup-shaped element 230, impermeable to liquids, housed in the body 110 of the capsule 100 in a seat 116 formed close to its flanged edge.
  • the cup-shaped element 230 comprises a central hole 231 wherein the stem 220 is slidably fitted.
  • the central hole 231 allows to correctly position the stem 220 into the body 110 of the capsule 100 during its assembly or packaging, as well as to guide the stem 220 axially facilitating its movement from the assembly position to the opening position.
  • the guiding function performed by the cup-shaped element 230 is particularly important also considering that the closing lever of an infusion group of a machine for the preparation of infused beverages is generally pivoted aside the capsule seat, so that when during the closing step the cover of a capsule is subjected to an axial load suitable to push the stem 220, as well as to a transverse load that may bend the stem 220 thus hindering its axial movement.
  • an axial guide for the stem 220 arranged close to the cover 120 of the capsule 100 it is thus possible to minimize bending problems of the stem 220 and to ensure its correct operation.
  • the stem 220 and the hole 231 of the cup-shaped element 230 of the insert 200 have substantially the same diameter so as to achieve a tight coupling in the assembly or packaging configuration of the capsule 100.
  • the cup-shaped element 230 divides the cavity of the body 110 of the capsule 100 into two parts, a lower part between the cup-shaped element 230 and the bottom 111, wherein the granular or particulate product is contained, and an upper part between the cup-shaped element 230 and the cover 120, wherein during packaging a second product or ingredient, such as milk powder or another substance, can be advantageously inserted.
  • the end portion of the stem 220 that protrudes from the hole 231 of the cup-shaped element 230 in the assembly configuration instead has a reduced cross section area relative to the portion of the stem 220 that engages the hole 231, thus allowing passage of a flow of infusion liquid and of a possible second product, from the upper part to the lower part of the cavity for the infusion of the beverage in the opening configuration of the capsule.
  • the end portion of the stem 220 is for example formed by a plurality of ribs 221 that define radial cavities 222 through which the infusion liquid can flow when the insert 200 is in the opening position.
  • Figures 6 to 9 schematically show the insert 200 in the assembly position and in the opening position, respectively.
  • the arrows of the longitudinal section of figure 9 schematically show the path of the infusion liquid through the cavity of the hollow body 110.
  • the end portion of the stem 220 might comprise a plurality of radial grooves.
  • end portion of the stem 220 might have a tapered shape, for example a frusto-conical shape.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Apparatus For Making Beverages (AREA)
  • Packages (AREA)

Claims (7)

  1. Capsule jetable (100) pour machines de préparation de boissons, ladite capsule (100) comprenant :
    i) un corps creux en forme de coupelle (110) adapté pour recevoir une dose mesurée d'un produit granulaire ou particulaire, ledit corps creux (110) comprenant un fond (111), dans lequel une ouverture débouchante (114) est formée et une paroi périphérique (112) sur le bord périphérique de laquelle, est formée une bride (113) ;
    ii) un couvercle (120) fixé, de manière étanche, sur ladite bride (113) ;
    iii) un film (130) appliqué sur ledit fond (111) à l'intérieur du corps creux (110) afin de sceller ladite ouverture débouchante (114) ;
    iv) un insert (200) logé dans ledit corps creux (110), ledit insert (200) comprenant une partie en forme de disque tronconique (210) dans le manteau (212) de laquelle est formée une pluralité d'ouvertures débouchantes (213) et dans la cavité de laquelle, sont formés des éléments de poinçonnement (214), et une tige (220) s'étendant de manière axiale à partir de la partie supérieure de ladite partie en forme de disque tronconique (210),
    caractérisée en ce que l'insert (200) est axialement mobile entre une position d'assemblage ou d'emballage, dans laquelle ladite partie en forme de disque tronconique (210) s'appuie sur le fond (111) du corps creux (110) et ladite tige (220) appuie contre ledit couvercle (120) le déformant vers l'extérieur, et une position d'ouverture, dans laquelle une extrémité libre de la tige (220) est avancée dans la direction axiale et sensiblement alignée avec ladite bride (113), et la partie en forme de disque (210) est aplatie sur le fond (111) et lesdits éléments de poinçonnement (214) interfèrent avec le film interne (130), le déchirant ainsi,
    et dans lequel l'insert (200) comprend en outre un élément imperméable au liquide en forme de coupelle (230) logé dans le corps (110) de la capsule (100) dans un siège (116) formé à proximité de son bord à bride, ledit élément en forme de coupelle (230) comprenant un trou central (231) dans lequel la tige (220) est montée de manière coulissante.
  2. Capsule (100) selon la revendication 1, dans laquelle la tige (220) et le trou (231) de l'élément en forme de coupelle (230) ont le même diamètre, de sorte qu'ils obtiennent un couplage étanche dans la position d'assemblage ou d'emballage et dans laquelle la tige (220) comprend une partie d'extrémité ayant une section transversale de surface réduite, ladite partie d'extrémité faisant saillie du trou (231) dans la position d'assemblage ou d'emballage.
  3. Capsule (100) selon la revendication 2, dans laquelle ladite partie d'extrémité de la tige (220) est composée d'une pluralité de nervures radiales (221) qui définissent des cavités (222) à travers lesquelles un liquide d'infusion peut s'écouler lorsque l'insert (200) est dans la position ouverte.
  4. Capsule (100) selon la revendication 2, dans laquelle ladite partie d'extrémité de la tige (220) comprend une pluralité de rainures radiales.
  5. Capsule (100) selon la revendication 2, dans laquelle ladite partie d'extrémité de la tige (220) a une forme tronconique.
  6. Capsule (100) selon l'une quelconque des revendications 1 à 5, dans laquelle le diamètre de la partie en forme de disque tronconique (210) de l'insert (200) dans la condition d'assemblage ou d'emballage non déformée est inférieur au diamètre du fond (111) du corps de capsule (110).
  7. Capsule (100) selon l'une quelconque des revendications 1 à 6, dans laquelle une pluralité de rainures circonférentielles (215) sont formées en faible relief dans le manteau (212) de la partie en forme de disque tronconique (210) de l'insert (200).* * *
EP16767217.9A 2015-09-15 2016-09-14 Capsules pour les machines à preparation des infusions Active EP3350102B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITUB2015A003624A ITUB20153624A1 (it) 2015-09-15 2015-09-15 Capsula monouso per macchine di erogazione di bevande in forma di infuso
PCT/EP2016/071682 WO2017046158A1 (fr) 2015-09-15 2016-09-14 Capsule jetable pour machines de distribution de boissons infusées

Publications (2)

Publication Number Publication Date
EP3350102A1 EP3350102A1 (fr) 2018-07-25
EP3350102B1 true EP3350102B1 (fr) 2019-08-28

Family

ID=54884215

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16767217.9A Active EP3350102B1 (fr) 2015-09-15 2016-09-14 Capsules pour les machines à preparation des infusions

Country Status (13)

Country Link
US (1) US20180237217A1 (fr)
EP (1) EP3350102B1 (fr)
JP (1) JP2018528052A (fr)
CN (1) CN108025865A (fr)
AU (1) AU2016321872A1 (fr)
CA (1) CA2995425A1 (fr)
ES (1) ES2751769T3 (fr)
HK (1) HK1255403A1 (fr)
IL (1) IL257862A (fr)
IT (1) ITUB20153624A1 (fr)
PT (1) PT3350102T (fr)
RU (1) RU2018113471A (fr)
WO (1) WO2017046158A1 (fr)

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US11832755B2 (en) * 2007-07-13 2023-12-05 Adrian Rivera Brewing material container for a beverage brewer
US10722066B2 (en) * 2010-12-04 2020-07-28 Adrian Rivera Windowed single serving brewing material holder
PL3023362T3 (pl) * 2010-07-22 2018-06-29 K Fee System Gmbh Kapsułka porcjowa ze znacznikiem
US8960999B1 (en) 2014-03-28 2015-02-24 Gudpod Holdings, Llc System for mixing beverages and method of doing the same
DE102017213368A1 (de) 2017-08-02 2019-02-07 BSH Hausgeräte GmbH Kapsel und Getränkesystem zur Herstellung eines Getränks
IT201800007403A1 (it) * 2018-07-20 2020-01-20 Capsula per la preparazione di una bevanda
US11805934B1 (en) * 2020-10-21 2023-11-07 Adrian Rivera Brewing material lid and container for a beverage brewer
CN115005677B (zh) * 2022-07-07 2023-06-02 湖南优享八点生物科技有限公司 一种胶囊杯及其冲泡方法

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DK1604915T4 (da) * 2002-01-16 2020-01-02 Nestle Sa Lukket kapsel med åbningsorgan
ITMO20070143A1 (it) * 2007-04-27 2008-10-28 Massimiliano Pineschi Capsula per contenere dosi di bevande solubili
IT1395924B1 (it) * 2009-09-25 2012-11-02 Masciadri Capsula di contenimento di un prodotto particolarmente per la preparazione di una bevanda alimentare
US9572451B2 (en) * 2011-03-07 2017-02-21 Cupsystem Company B.V. Disposable package and system for preparation of a liquid product
ITMI20120247A1 (it) * 2012-02-20 2013-08-21 Illycaffe Spa Cartuccia per l'ottenimento di una bevanda.
EP3044125B1 (fr) * 2013-09-09 2017-04-12 Nestec S.A. Capsule, procédé et système de préparation d'un produit alimentaire ou de boisson visqueuse
CH709296B1 (de) * 2014-02-21 2022-08-15 Delica Ag Kapsel mit einem vorzugsweise rotationssymmetrisch ausgebildeten Kapselkörper.
CH709273A2 (de) * 2014-02-21 2015-08-28 Delica Ag Kapsel umfassend einen vorzugsweise rotationssymmetrisch ausgebildeten Kapselkörper.
CH709598A2 (de) * 2014-05-06 2015-11-13 Delica Ag Portionierbehälter für eine Kapsel zur Getränkzubereitung.

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Title
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Also Published As

Publication number Publication date
EP3350102A1 (fr) 2018-07-25
ITUB20153624A1 (it) 2017-03-15
PT3350102T (pt) 2019-11-06
ES2751769T3 (es) 2020-04-01
AU2016321872A1 (en) 2018-03-15
CA2995425A1 (fr) 2017-03-23
HK1255403A1 (zh) 2019-08-16
IL257862A (en) 2018-05-31
WO2017046158A1 (fr) 2017-03-23
JP2018528052A (ja) 2018-09-27
US20180237217A1 (en) 2018-08-23
RU2018113471A (ru) 2019-10-18
CN108025865A (zh) 2018-05-11

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