EP3328435A4 - Pharmaceutical composition with improved storage stability and method for preparing the same - Google Patents
Pharmaceutical composition with improved storage stability and method for preparing the same Download PDFInfo
- Publication number
- EP3328435A4 EP3328435A4 EP16830851.8A EP16830851A EP3328435A4 EP 3328435 A4 EP3328435 A4 EP 3328435A4 EP 16830851 A EP16830851 A EP 16830851A EP 3328435 A4 EP3328435 A4 EP 3328435A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- preparing
- pharmaceutical composition
- same
- storage stability
- improved storage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20150106627 | 2015-07-28 | ||
PCT/KR2016/008267 WO2017018818A1 (en) | 2015-07-28 | 2016-07-28 | Pharmaceutical composition with improved storage stability and method for preparing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3328435A1 EP3328435A1 (en) | 2018-06-06 |
EP3328435A4 true EP3328435A4 (en) | 2019-03-13 |
Family
ID=57885186
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP16830851.8A Withdrawn EP3328435A4 (en) | 2015-07-28 | 2016-07-28 | Pharmaceutical composition with improved storage stability and method for preparing the same |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP3328435A4 (en) |
JP (1) | JP2018521103A (en) |
KR (1) | KR101787451B1 (en) |
CN (1) | CN106659681A (en) |
AU (1) | AU2016299546B2 (en) |
BR (1) | BR112018001725A2 (en) |
CA (1) | CA2993925A1 (en) |
HK (1) | HK1249442A1 (en) |
IL (1) | IL257188A (en) |
MX (1) | MX2018001221A (en) |
RU (1) | RU2018107057A (en) |
WO (1) | WO2017018818A1 (en) |
ZA (1) | ZA201801188B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102144479B1 (en) * | 2018-05-24 | 2020-08-13 | 주식회사 덱스레보 | Composition for tissue repair treatment and methods of manufacturing the same |
KR102251192B1 (en) * | 2020-08-07 | 2021-05-13 | 주식회사 덱스레보 | Composition for tissue repair treatment and methods of manufacturing the same |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001085216A1 (en) * | 2000-05-12 | 2001-11-15 | Samyang Corporation | Method for the preparation of polymeric micelle via phase separation of block copolymer |
WO2001087345A1 (en) * | 2000-05-17 | 2001-11-22 | Samyang Corporation | Stable polymeric micelle-type drug composition and method for the preparation thereof |
US20100280214A1 (en) * | 2007-12-31 | 2010-11-04 | Samyang Corporation | Highly pure amphiphilic copolymer comprising hydrophobic block from alpha-hydroxy acid and process for the preparation thereof |
US20130345297A1 (en) * | 2007-12-31 | 2013-12-26 | Samyang Biopharmaceuticals Corporation | Method for stabilizing amphiphilic block copolymer micelle composition containing poorly water-soluble drug |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003033592A1 (en) * | 2001-10-18 | 2003-04-24 | Samyang Corporation | Polymeric micelle composition with improved stability |
EP1967854B8 (en) | 2007-03-06 | 2010-12-29 | Cell Therapeutics, Inc. | Method for determining the amount of conjugated taxane in polyglutamic acid-taxane conjugates |
KR101024742B1 (en) * | 2007-12-31 | 2011-03-24 | 주식회사 삼양사 | Amphiphilic Block Copolymer Micelle Composition Containing Taxane and Manufacturing Process of The Same |
EP2201935B1 (en) * | 2008-12-26 | 2020-07-08 | Samyang Biopharmaceuticals Corporation | Polymeric micelle composition containing a poorly soluble drug and preparation method of the same |
CN102218027B (en) * | 2011-04-22 | 2014-07-02 | 上海谊众生物技术有限公司 | Polymer micelle lyophilized agent encapsulating insoluble antitumor drug |
CN103768013A (en) * | 2014-01-17 | 2014-05-07 | 丽珠医药集团股份有限公司 | Paclitaxel polymer micelle by using refined amphiphilic block copolymer as carrier |
-
2016
- 2016-07-27 KR KR1020160095414A patent/KR101787451B1/en active IP Right Grant
- 2016-07-28 EP EP16830851.8A patent/EP3328435A4/en not_active Withdrawn
- 2016-07-28 WO PCT/KR2016/008267 patent/WO2017018818A1/en active Application Filing
- 2016-07-28 AU AU2016299546A patent/AU2016299546B2/en active Active
- 2016-07-28 CA CA2993925A patent/CA2993925A1/en not_active Abandoned
- 2016-07-28 MX MX2018001221A patent/MX2018001221A/en unknown
- 2016-07-28 RU RU2018107057A patent/RU2018107057A/en unknown
- 2016-07-28 BR BR112018001725A patent/BR112018001725A2/en not_active Application Discontinuation
- 2016-07-28 JP JP2018504241A patent/JP2018521103A/en active Pending
- 2016-07-28 CN CN201680001948.6A patent/CN106659681A/en active Pending
-
2018
- 2018-01-28 IL IL257188A patent/IL257188A/en unknown
- 2018-02-21 ZA ZA2018/01188A patent/ZA201801188B/en unknown
- 2018-07-13 HK HK18109127.7A patent/HK1249442A1/en unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001085216A1 (en) * | 2000-05-12 | 2001-11-15 | Samyang Corporation | Method for the preparation of polymeric micelle via phase separation of block copolymer |
WO2001087345A1 (en) * | 2000-05-17 | 2001-11-22 | Samyang Corporation | Stable polymeric micelle-type drug composition and method for the preparation thereof |
US20100280214A1 (en) * | 2007-12-31 | 2010-11-04 | Samyang Corporation | Highly pure amphiphilic copolymer comprising hydrophobic block from alpha-hydroxy acid and process for the preparation thereof |
US20130345297A1 (en) * | 2007-12-31 | 2013-12-26 | Samyang Biopharmaceuticals Corporation | Method for stabilizing amphiphilic block copolymer micelle composition containing poorly water-soluble drug |
Non-Patent Citations (3)
Title |
---|
KIM S C ET AL: "In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy", JOURNAL OF CONTROLLED RELEASE, ELSEVIER, AMSTERDAM, NL, vol. 72, no. 1-3, 14 May 2001 (2001-05-14), pages 191 - 202, XP027296131, ISSN: 0168-3659, [retrieved on 20010514] * |
See also references of WO2017018818A1 * |
ZHU K J ET AL: "PREPARATION, CHARACTERIZATION, AND PROPERTIES OF POLYLACTIDE (PLA)-POLY(ETHYLENE GLYCOL) (PEG) COLOYMERS: A POTENTIAL DRUG CARRIER", JOURNAL OF APPLIED POLYMER SCIENCE, JOHN WILEY & SONS, INC, US, vol. 39, no. 1, 1 January 1990 (1990-01-01), pages 1 - 09, XP000650366, ISSN: 0021-8995, DOI: 10.1002/APP.1990.070390101 * |
Also Published As
Publication number | Publication date |
---|---|
BR112018001725A2 (en) | 2018-09-18 |
KR101787451B1 (en) | 2017-10-19 |
MX2018001221A (en) | 2018-04-24 |
KR20170015199A (en) | 2017-02-08 |
RU2018107057A3 (en) | 2019-08-28 |
CA2993925A1 (en) | 2017-02-02 |
IL257188A (en) | 2018-03-29 |
EP3328435A1 (en) | 2018-06-06 |
HK1249442A1 (en) | 2018-11-02 |
AU2016299546B2 (en) | 2019-05-02 |
ZA201801188B (en) | 2018-12-19 |
WO2017018818A1 (en) | 2017-02-02 |
AU2016299546A1 (en) | 2018-03-08 |
JP2018521103A (en) | 2018-08-02 |
CN106659681A (en) | 2017-05-10 |
RU2018107057A (en) | 2019-08-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL289099A (en) | Methods for the storage of whole blood, and compositions thereof | |
EP3364951A4 (en) | Nicotine composition for vaping devices and vaping devices employing the same | |
EP3197867A4 (en) | Novel 4-methoxy pyrrole derivatives or salts thereof and pharmaceutical composition comprising the same | |
EP3328562A4 (en) | Clean-place method and system and composition for the same | |
EP3319710A4 (en) | Composition and system for gas storage | |
EP3130355A4 (en) | Pharmaceutical composition containing pregabalin with improved stability and method for preparing same | |
EP3331947A4 (en) | Silica-based biomolecule carrier, pharmaceutical composition comprising the same, preparation method and use thereof | |
EP3330379A4 (en) | Aptamer against insulin receptor and pharmaceutical composition containing the same | |
HRP20200104T8 (en) | Novel heterocyclic compound, method for preparing the same, and pharmaceutical composition comprising the same | |
EP3207149A4 (en) | Pharmaceutical composition with improved stability | |
EP3185873A4 (en) | Pharmaceutical composition and methods | |
EP3328368A4 (en) | Compounds and pharmaceutical composition associated with ubiquitination-proteasome system | |
HK1249442A1 (en) | Pharmaceutical composition with improved storage stability and method for preparing the same | |
HK1249439A1 (en) | Pharmaceutical composition with improved storage stability and method for preparing the same | |
EP3349748A4 (en) | Composition and methods thereof | |
EP3175845A4 (en) | Pharmaceutical composition provided with abuse-prevention function | |
EP3384933A4 (en) | Anhydrosugar alcohol composition having enhanced storage stability, and anhydrosugar alcohol storage method | |
EP3305283A4 (en) | Stabilized pharmaceutical composition and method for preparing same | |
HK1249440A1 (en) | Pharmaceutical composition with improved storage stability and method for preparing the same | |
EP3230940A4 (en) | Method for constructing interactive digital catalog, and computer-readable storage medium and interactive digital catalog using the same | |
EP3143017A4 (en) | Bicyclic derivatives and pharmaceutical composition including the same | |
EP3175851A4 (en) | Use of butenylphthalide, usage method thereof and method for preparing same into pharmaceutical composition | |
HK1249441A1 (en) | Pharmaceutical composition with improved storage stability and method for preparing the same | |
EP3310761A4 (en) | Platelet storage methods and compositions for same | |
EP3251672A4 (en) | Pharmaceutical composition and preparation method therefor |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20180228 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1249442 Country of ref document: HK |
|
DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20190212 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 31/337 20060101ALI20190206BHEP Ipc: A61K 47/34 20170101AFI20190206BHEP Ipc: A61K 9/19 20060101ALI20190206BHEP Ipc: A61K 9/107 20060101ALI20190206BHEP Ipc: A61K 31/122 20060101ALI20190206BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20190912 |