EP3294053A4 - Method & apparatus for continuous automated perfusion system harvesting from in-situ filtration probe - Google Patents

Method & apparatus for continuous automated perfusion system harvesting from in-situ filtration probe Download PDF

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Publication number
EP3294053A4
EP3294053A4 EP16793325.8A EP16793325A EP3294053A4 EP 3294053 A4 EP3294053 A4 EP 3294053A4 EP 16793325 A EP16793325 A EP 16793325A EP 3294053 A4 EP3294053 A4 EP 3294053A4
Authority
EP
European Patent Office
Prior art keywords
perfusion system
continuous automated
situ filtration
automated perfusion
filtration probe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP16793325.8A
Other languages
German (de)
French (fr)
Other versions
EP3294053A1 (en
Inventor
Michael BIKSACKY
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Flownamics Analytical Instruments Inc
Original Assignee
Flownamics Analytical Instruments Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flownamics Analytical Instruments Inc filed Critical Flownamics Analytical Instruments Inc
Publication of EP3294053A1 publication Critical patent/EP3294053A1/en
Publication of EP3294053A4 publication Critical patent/EP3294053A4/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F1/00—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow
    • G01F1/704—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow using marked regions or existing inhomogeneities within the fluid stream, e.g. statistically occurring variations in a fluid parameter
    • G01F1/708—Measuring the time taken to traverse a fixed distance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F15/00—Details of, or accessories for, apparatus of groups G01F1/00 - G01F13/00 insofar as such details or appliances are not adapted to particular types of such apparatus
    • G01F15/001—Means for regulating or setting the meter for a predetermined quantity
    • G01F15/003—Means for regulating or setting the meter for a predetermined quantity using electromagnetic, electric or electronic means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F15/00—Details of, or accessories for, apparatus of groups G01F1/00 - G01F13/00 insofar as such details or appliances are not adapted to particular types of such apparatus
    • G01F15/005—Valves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F25/00—Testing or calibration of apparatus for measuring volume, volume flow or liquid level or for metering by volume
    • G01F25/10—Testing or calibration of apparatus for measuring volume, volume flow or liquid level or for metering by volume of flowmeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01P—MEASURING LINEAR OR ANGULAR SPEED, ACCELERATION, DECELERATION, OR SHOCK; INDICATING PRESENCE, ABSENCE, OR DIRECTION, OF MOVEMENT
    • G01P5/00—Measuring speed of fluids, e.g. of air stream; Measuring speed of bodies relative to fluids, e.g. of ship, of aircraft
    • G01P5/18—Measuring speed of fluids, e.g. of air stream; Measuring speed of bodies relative to fluids, e.g. of ship, of aircraft by measuring the time taken to traverse a fixed distance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F23/00—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm
    • G01F23/22—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Aviation & Aerospace Engineering (AREA)
  • Electromagnetism (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP16793325.8A 2015-05-08 2016-05-09 Method & apparatus for continuous automated perfusion system harvesting from in-situ filtration probe Ceased EP3294053A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562158920P 2015-05-08 2015-05-08
US201562162862P 2015-05-18 2015-05-18
PCT/US2016/031487 WO2016183016A1 (en) 2015-05-08 2016-05-09 Method & apparatus for continuous automated perfusion system harvesting from in-situ filtration probe

Publications (2)

Publication Number Publication Date
EP3294053A1 EP3294053A1 (en) 2018-03-21
EP3294053A4 true EP3294053A4 (en) 2019-03-06

Family

ID=57222367

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16793325.8A Ceased EP3294053A4 (en) 2015-05-08 2016-05-09 Method & apparatus for continuous automated perfusion system harvesting from in-situ filtration probe

Country Status (3)

Country Link
US (2) US10214716B2 (en)
EP (1) EP3294053A4 (en)
WO (1) WO2016183016A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10214716B2 (en) 2015-05-08 2019-02-26 Flownamics Analytical Instruments, Inc. Method and apparatus for continuous automated perfusion system harvesting from in-situ filtration probe

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WO2003078564A2 (en) * 2002-03-15 2003-09-25 St3 Development Corporation Bioreactor for conditioning intravascular tissue engineered medical products.
US20080302178A1 (en) * 2007-06-11 2008-12-11 Jeffrey Karg Method and system for dispensing precise reagent volumes
WO2013040444A1 (en) * 2011-09-16 2013-03-21 Amgen Inc. Pre-programmed non-feedback controlled continuous feeding of cell cultures
US8809042B1 (en) * 2007-10-29 2014-08-19 The United States Of America As Represented By The Secretary Of The Army Plug flow reactor process for anaerobic cellulosic ethanol

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US3693436A (en) * 1970-08-28 1972-09-26 Lab Data Control Inc Liquid flow meter
US3668936A (en) 1970-12-15 1972-06-13 Technicon Instr Method and apparatus for sampling
US3759667A (en) 1971-10-22 1973-09-18 Damon Corp Apparatus for aspirating precise volumes of fluid sample
DE2354091A1 (en) 1973-10-29 1975-05-07 Ruhrchemie Ag METHOD AND DEVICE FOR SAMPLING FROM A FLOW OF LIQUID
CH582878A5 (en) * 1974-09-23 1976-12-15 Contraves Ag
DE2448353B2 (en) 1974-10-10 1977-05-05 W.C. Heraeus Gmbh, 6450 Hanau DEVICE FOR THE CARRIAGE-FREE TRANSFER OF A SPECIFIED VOLUME OF SUCCESSIVE LIQUID SAMPLES
US4450862A (en) * 1981-02-13 1984-05-29 Syntex (U.S.A.) Inc. Pinch valve assembly
WO1987003092A1 (en) 1985-11-07 1987-05-21 Ionode Pty. Ltd. Analytic apparatus and method
DE3608227C2 (en) * 1986-03-12 1999-06-24 Abc Biotechnologie Bioverfahre Arrangement for liquid chromatography
US4825706A (en) * 1987-11-23 1989-05-02 The Babcock & Wilcox Company Flowmeter for a moving packed bed
CA1328359C (en) 1989-03-27 1994-04-12 Michael D. Mintz Fluid sample collection and delivery system and methods particularly adapted for body fluid sampling
US5137054A (en) * 1991-12-12 1992-08-11 Crystal Fluid Power, Inc. Flow and pressure responsive valve
WO1994002945A1 (en) 1992-07-17 1994-02-03 Ionode Pty. Ltd. Recalibrating apparatus and method
US5355735A (en) * 1993-02-23 1994-10-18 Datrend Systems Inc. Apparatus for metering liquid flow
US6203759B1 (en) 1996-05-31 2001-03-20 Packard Instrument Company Microvolume liquid handling system
US5487313A (en) 1993-11-30 1996-01-30 Microsensor Technology, Inc. Fluid-lock fixed-volume injector
US5834314A (en) 1994-11-07 1998-11-10 Abbott Laboratories Method and apparatus for metering a fluid
US6130098A (en) 1995-09-15 2000-10-10 The Regents Of The University Of Michigan Moving microdroplets
USRE38281E1 (en) 1996-07-26 2003-10-21 Biodot, Inc. Dispensing apparatus having improved dynamic range
US6289714B1 (en) 1996-10-04 2001-09-18 TARTRE ANDRé Method for testing soil contamination, and probe therefor
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Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003078564A2 (en) * 2002-03-15 2003-09-25 St3 Development Corporation Bioreactor for conditioning intravascular tissue engineered medical products.
US20080302178A1 (en) * 2007-06-11 2008-12-11 Jeffrey Karg Method and system for dispensing precise reagent volumes
US8809042B1 (en) * 2007-10-29 2014-08-19 The United States Of America As Represented By The Secretary Of The Army Plug flow reactor process for anaerobic cellulosic ethanol
WO2013040444A1 (en) * 2011-09-16 2013-03-21 Amgen Inc. Pre-programmed non-feedback controlled continuous feeding of cell cultures

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2016183016A1 *

Also Published As

Publication number Publication date
US20160326481A1 (en) 2016-11-10
US10214716B2 (en) 2019-02-26
US10975349B2 (en) 2021-04-13
EP3294053A1 (en) 2018-03-21
WO2016183016A1 (en) 2016-11-17
US20190338236A1 (en) 2019-11-07

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