EP3204096A1 - Nebulizer with stationary screen - Google Patents
Nebulizer with stationary screenInfo
- Publication number
- EP3204096A1 EP3204096A1 EP15788144.2A EP15788144A EP3204096A1 EP 3204096 A1 EP3204096 A1 EP 3204096A1 EP 15788144 A EP15788144 A EP 15788144A EP 3204096 A1 EP3204096 A1 EP 3204096A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- reservoir
- sieve
- piezoelectric
- liquid
- screen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/003—Particle size control by passing the aerosol trough sieves or filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0085—Inhalators using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/08—Inhaling devices inserted into the nose
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0638—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers spray being produced by discharging the liquid or other fluent material through a plate comprising a plurality of orifices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
- A61M16/0816—Joints or connectors
- A61M16/0833—T- or Y-type connectors, e.g. Y-piece
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
- A61M16/147—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase the respiratory gas not passing through the liquid container
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0272—Electro-active or magneto-active materials
- A61M2205/0294—Piezoelectric materials
Definitions
- the present invention relates to a medical aerosol generation system and more particularly to a fixed screen nebulization device avoiding any malfunctioning and any risk of contamination of the drug in particular.
- nebulizer devices are used to deliver large quantities of various drugs directly into the patient's airways. They thus provide a rapid and selective therapeutic action at the level of the pathological site. It should be noted that nebulization can be defined as the transformation of a medicinal liquid into a medicinal aerosol.
- the term “nebulize” is used as a synonym for "turning a liquid into an aerosol”.
- a nebulizing apparatus comprises a reservoir into which the liquid to be sprayed is introduced, a nebulization chamber, where the aerosol is produced, and a pneumatic or piezoelectric energy source used to create the aerosol.
- Sieve nebulizer systems have the advantage of being quiet, portable and small. They consist of an electronic power supply connected to the nebulizer. The electronic power supply can operate on mains or batteries.
- the aerosol generator is composed of a sieve pierced with a large quantity microscopic holes with a diameter of 2 ⁇ to 10 ⁇ , said holes being obtained by electrophoresis or by laser drilling of the sieve. The passage of the medicinal liquid through the sieve transforms the liquid into aerosol droplets of size equivalent to the size of the holes of said sieve.
- the fixed screen aerosol generator uses a piezoelectric in contact with the medicinal liquid.
- the piezoelectric vibration (between 0HzHz and 500KHz) is transmitted to the liquid forcing its passage through the screen holes to detach breathable droplets out of the screen.
- the aerosol produced is then mobilized by the patient out of the nebulizer.
- the piezoelectric is separated from the sieve.
- the vibrating screen aerosol generator uses a piezoelectric device surrounding the screen to vibrate it (between the OKHz and 500KHz). The drug solution then in contact with the sieve will be drawn through the conical holes as it deforms toward the solution reservoir.
- the solution then located at the edge of the sieve will detach to form respirable particles.
- the aerosol is then mobilized by the patient out of the nebulizer.
- the piezoelectric is secured to the sieve.
- FIG. 1 is a schematic representation of a nebulizer according to the teaching of these documents, said nebulizer operates on the principle of the vibration of a cylindrical piezoelectric quartz (1), extending horizontally and pushing the liquid through a static sieve (2) which extends vertically and which is held by a hollow cylinder (3).
- the cylindrical piezoelectric quartz (1) is powered by an electrical signal with two pins (4) and (5).
- the liquid is placed in a tank (6) closed by an upper lid (7) and having a hopper-shaped upper part and a substantially parallelepipedal lower part, one of whose side walls receives the sieve (2) and whose wall opposite side receives the cylindrical piezoelectric quartz (1), the cylindrical end of the piezoelectric quartz is positioned near the sieve.
- quartz vibration causes the liquid to move from the base of the quartz cylinder to the opposite cylindrical end of the quartz and the liquid is pushed through the sieve (2). Micro droplets are thus ejected on the other side of the sieve (2).
- Nebulizers sold by Kjump® are also known operating on the same principle as the nebulizer described in JP 4215765.
- said nebulizer comprises a quartz piezoelectric (1) and a static sieve (2) respectively integral with the bottom wall and the upper wall of a substantially parallelepiped tank (6), said tank (6) being closed by an upper cover (7).
- the cylindrical piezoelectric quartz (1) is fed by an electrical signal with two pins (4) and (5), the free end of the piezoelectric quartz (1) is positioned within 2 mm of the static sieve (2).
- the nebulizer allows the generation of an aerosol along a vertical axis from bottom to top.
- This type of static screen nebulizer although of inexpensive design because of the dissociation of the sieve with piezoelectric quartz, has the disadvantage of operating only in a particular orientation, that is to say a generation. aerosol from bottom to top or horizontally.
- this type of nebulizer presents a risk of malfunction of the sieve. Indeed, if the patient saliva in the system, the saliva can come by gravity to be placed at the level of the sieve and prevent its operation by obstructing the holes of the sieve.
- the aerosol itself produced by the nebulizer can also be deposited on the aerosol transport circuits (tubing) and slide by gravity to come into contact with the screen and thus obstruct it.
- this type of nebulizer presents a risk of contamination of the drug.
- a liquid substance deposited on the outer side of the sieve due to slipping liquid can be transferred / pumped to the other side of the sieve (EP1875936) and thus be mixed in the nebulizer tank with the drug, contaminating it.
- a different orientation of these nebulizers, so that the sieve is oriented downwards does not allow operation of these nebulizers. Indeed, the geometry of the tanks and the position of the lids do not allow a correct nebulization when said tanks are almost empty and respectively a loading of the tanks in liquid.
- Vibrating screen nebulizers such as those marketed by the company Aerogen® and described in US patent application US 2003/150445 are also known.
- This document describes, with reference to FIG. 3, a nebulizer operating on the basis of the vibration of a sieve (2) set in motion by a piezoelectric quartz (1).
- the piezoelectric quartz (1) is annular in shape and surrounds the screen (2) placed at its center.
- the piezoelectric quartz (1) is powered by an electrical signal with two pins (4) and (5).
- the liquid is placed by an upper cover (7) in a reservoir (6) of the nebulizer which by gravity comes into contact with the top of the screen (2).
- the screen (2) vibrates, the liquid is pumped through the screen and ejected from the other side of said screen.
- the aerosol is produced from top to bottom and vertically.
- This principle of downward aerosol generation has the advantage of being adapted for use with inhalation chambers and of providing constant performance during the time of nebulization. Indeed, the use of a screen nebulizer projecting the aerosol in one direction can be followed by a loss on the walls. In this case the aerosol deposited on the walls will not flow to the sieve of the tank and will not obstruct the sieve and thus stop the nebulization.
- This nebulization system nevertheless has the major disadvantage of a higher manufacturing cost than the static screen nebulizer. Indeed, the assembly of annular piezoelectric quartz and the sieve at its center poses complex manufacturing problems and associated costs not negligible.
- One of the aims of the invention is therefore to overcome these disadvantages by providing a nebulization device of simple and inexpensive design, avoiding any dis operation and any contamination of the liquid to be sprayed.
- the nebulizing device comprises at least one reservoir capable of containing a liquid, said reservoir comprising an opening on its outer surface for pouring said liquid into the reservoir, a fixed screen comprising a plurality of microscopic holes and one side in contact with the liquid contained in the reservoir is disposed facing a piezoelectric device which is in contact with the same liquid contained in the reservoir so that the vibrations of the piezoelectric device are transmitted to the liquid forcing its passage through the screen holes to generate an aerosol, from a screen emission face.
- the opening of the reservoir for its filling in an operating position of said device is located above the sieve face arranged horizontally in the operating position and facing of the piezoelectric device, in order to produce, in said operating position, an aerosol along an axis of the order of 30 degrees relative to the vertical, from top to bottom.
- the static screen nebulizer according to the invention produces an aerosol along a vertical axis from bottom to top.
- the liquid in contact with the sieve allows the direct nebulization of the liquid while the operating principle of the fixed screen nebulizers of the prior art theoretically requires the contact of the liquid at the base of the piezoelectric quartz to allow the Controlled feeding of the liquid to the screen to generate aerosol.
- air bubbles produced by the sieve in the liquid are evacuated by the face of the sieve disposed opposite the piezoelectric.
- the vibration of the piezo not only causes a thrust of the liquid to the sieve but also a suction of the outside air through the sieve, thereby generating air bubbles in the tank.
- the invention is also remarkable in that the arrangement of the sieve facing the tank allows the natural evacuation of air bubbles by ascent. These air bubbles are not trapped against the sieve and do not prevent the passage of liquid through the sieve contrary to the arrangement as shown in Figure 2.
- the tank has a frustoconical lower portion whose smallest base forms a lower opening which is closed by the sieve maintained on the underside of said tank to the right of said lower opening by a lower cylindrical piece.
- the frustoconical section of the tank base minimizes the residual volume of liquid in the tank, at the end of nebulization.
- the piezoelectric device consists of a vertical piezoelectric cylinder extending inside the frustoconical lower part of the tank, at right of the sieve, perpendicular to said sieve and at a maximum distance of 2 mm. of the last.
- the holes of the sieve have a diameter of between 1 and 10 ⁇ .
- said screen comprises between 100 and 10,000 holes.
- the reservoir has a form of revolution comprising a cylindrical upper portion having a central cylindrical recess and a frustoconical lower portion.
- Said piezoelectric cylinder extends coaxially with the axis of revolution of the reservoir.
- the device comprises a control circuit of the piezoelectric device adapted to vibrate said piezoelectric cylinder at a frequency between 10 and 500 KHz.
- the lower cylindrical piece is integral with the upper wall of an interface consisting of a container comprising a bottom wall, at least one side wall, an upper wall, and a mouthpiece or face mask, said lower cylindrical piece opening in the container whose upper wall is equipped with a vent.
- the tip consists of a mouthpiece or a nosepiece.
- the device comprises a respirator comprising an inspiration line and an exhalation line connected to a flexible intubation probe by a Y-shaped piece, said inspiratory line and / or the the end of the Y-shaped part comprises a bypass pipe adapted to receive the lower cylindrical part so that, during the inspiratory phases, the aerosol is projected into the inspiration pipe and / or the Y-shaped piece.
- FIG. 1 is a schematic representation of a fixed screen nebulizer of the prior art
- FIG. 2 is a schematic representation of a second fixed screen nebulizer of the prior art
- FIG. 3 is a schematic representation of a vibrating screen nebulizer of the prior art
- FIG. 4 is a schematic representation of a fixed screen nebulizer according to the invention.
- FIG. 5 is a schematic representation of a first variant embodiment of the fixed screen nebulizer according to the invention.
- FIG. 6 is a diagrammatic representation of a detail of the first embodiment variant of the fixed screen nebulizer according to the invention.
- FIG. 7 is a schematic representation of a second embodiment of the fixed screen nebulizer according to the invention.
- a nebulizing device which is particularly intended for medical aerosol generation systems whose function is to transform a medicament in liquid form into an aerosol to be administered in the tracts. respiratory air of a patient; however, it is obvious that the nebulizing device can find many applications in other technical fields without departing from the scope of the invention.
- the same elements have been designated by the same references in the various figures.
- the various sectional views are not necessarily drawn to scale and the dimensions of the elements may have been exaggerated to facilitate the understanding of the invention.
- the nebulizing device comprises a reservoir (6) able to contain a liquid, such as a medicament for example, said reservoir (6) having an upper opening (O) for the pouring said liquid into the reservoir (6) and a fixed screen (2) comprising a plurality of microscopic holes.
- the opening (O) of the reservoir (6) for its filling in an operating position of said device is arranged facing the piezoelectric device (1), in order to produce, in said operating position, an aerosol along a substantially vertical axis, of the order of 30 degrees, from top to bottom.
- said reservoir (6) comprises a frustoconical lower part
- the reservoir (6) has a shape of revolution comprising a cylindrical upper part (6b) having a central cylindrical recess (6c), said central recess (6c) being coaxial with the upper part (6b) and a frustoconical lower part (6a) whose vertical axis of revolution is coaxial with the axis of revolution of the upper part (6b) of the tank.
- the upper opening (O) of the upper part (6b) of the reservoir (6) which has an annular shape has a cover (7) adapted to close said opening and allowing its opening and closing repeated to ensure the charging of the reservoir (6) in liquid.
- the piezoelectric device (1) consists of a vertical piezoelectric cylinder extending inside the frustoconical lower part (6a) of the reservoir (6), at the sieve (2) and perpendicular to said sieve (2). ).
- the lower end of said piezoelectric cylinder (1) extends at a maximum distance of 2 mm from said screen (2).
- the axis of the piezoelectric cylinder (1) is substantially coaxial with the axis of revolution of the lower part (6a) and the upper part (6b) of the reservoir (6).
- the piezoelectric cylinder (1) is powered by an electrical signal by means of two pins (4) and (5) which extend above the lower part (6a) of the tank (6), on the inside the central cylindrical recess (6c).
- said sieve (2) is substantially circular and has a plurality of holes, between 100 and 10000 holes, whose diameter is between 1 and 10 ⁇ , said holes being obtained in a well-known manner by electrophoresis or by laser drilling. sieves in particular.
- the nebulization device combines the advantages of a low cost of production and performance while limiting the risks associated with the flow of liquid on the screen.
- the liquid in contact with the screen (2) allows the direct nebulization of the liquid even when the piezoelectric cylinder (1) is not in contact with the liquid while the static screen nebulizers of the prior art theoretically requires contact of the liquid with the lower end of the piezoelectric cylinder (1) to allow controlled feeding of the liquid to the screen to generate aerosol.
- said device comprises, in the same way than previously, a reservoir (6) adapted to contain a liquid, said reservoir (6) comprising an upper opening for pouring said liquid into the reservoir (6), a screen (2) comprising a plurality of microscopic holes and a piezoelectric device (1) in contact with the liquid contained in the reservoir (6).
- Said reservoir (6) comprises an inclined lower part (6a) in the direction of the lower opening which is closed by the sieve (2) maintained on the lower face of said reservoir (6) in line with said lower opening by a lower cylindrical part (3).
- the upper part (6b) of the reservoir is substantially cylindrical.
- the piezoelectric device (1) consists of a vertical piezoelectric cylinder extending inside the frustoconical lower part (6a) of the reservoir (6), at the sieve (2) and perpendicular to said sieve (2). ).
- the lower end of said piezoelectric cylinder (1) extends at a maximum distance of 2 mm from said sieve (2) and the axis of the piezoelectric cylinder (1) is substantially coaxial with the axis of revolution of the lower part (6a) of the tank (6).
- the piezoelectric cylinder (1) is powered by an electrical signal by means of two pins (4) and (5) which extend above the lower part (6a) of the tank (6), along the side wall of the cylindrical upper portion (6b) of said reservoir (6).
- the opening of the reservoir (6) is offset laterally relative to the sieve assembly (2) - piezoelectric device (1).
- this variant of execution differs from that previously described in that the upper part (6b) of the tank is substantially cylindrical and contains no recess, the vertical axis of revolution of the upper part (6b) extending parallel to the vertical axis of revolution of the lower portion (6a) of the reservoir (6) receiving the sieve (2) being offset.
- the upper opening of the upper part (6b) of the tank (6) which has a circular shape comprises a disk-shaped lid (7) adapted to close said opening and allowing its repeated opening and closing to ensure loading the reservoir (6) with liquid.
- said device comprises, in the same manner as above, a reservoir (6) adapted to contain a liquid, said reservoir (6 ) comprising an upper opening (O) for pouring said liquid into the reservoir (6), a sieve (2) comprising a plurality of microscopic holes and a piezoelectric device (1) in contact with the liquid contained in the reservoir (6).
- Said reservoir (6) comprises a frustoconical lower portion (6a) whose smallest base forms the lower opening which is closed by the sieve (2) maintained on the lower face of said reservoir (6) in line with said lower opening by a lower cylindrical part (3).
- the upper part (6b) of the reservoir is substantially cylindrical.
- the piezoelectric device (1) consists of a vertical piezoelectric cylinder extending inside the frustoconical lower part (6a) of the reservoir (6), at the sieve (2) and perpendicular to said sieve (2). ).
- the lower end of said piezoelectric cylinder (1) extends at a distance of at most 2 mm from said screen (2) and the axis of the piezoelectric cylinder (1) is substantially coaxial with the axis of revolution the lower part (6a) of the tank (6).
- the piezoelectric cylinder (1) is powered by an electrical signal by means of two pins (4) and (5) which extend above the lower part (6a) of the tank (6), along the side wall of the cylindrical upper portion (6b) of said reservoir (6).
- the device is distinguished in that it comprises a respirator (8) comprising an inspiration line (9) and an exhalation line (10) connected to a probe flexible intubation (11) by a Y-shaped piece (12), said inspiratory pipe (9) having a T-shaped bypass duct (13) adapted to receive the lower cylindrical piece (3) so that during the inspiratory phases, the aerosol is projected into the inspiration pipe (9).
- a respirator comprising an inspiration line (9) and an exhalation line (10) connected to a probe flexible intubation (11) by a Y-shaped piece (12), said inspiratory pipe (9) having a T-shaped bypass duct (13) adapted to receive the lower cylindrical piece (3) so that during the inspiratory phases, the aerosol is projected into the inspiration pipe (9).
- the aerosol produced is transported through the inspiration pipe (9), the Y-piece (12) and the probe (11) to the patient.
- the exhaled air by the patient is directed through the intubation probe (11), the Y-piece (12) and the exhalation line (10) to be expelled into the ambient air.
- the aerosol is produced by the nebulizer in the inspiratory conduit (9) and is stored for the next inspiratory phase.
- the branch line (13) may be integral with the Y-shaped part (12) without departing from the scope of the invention.
- said device comprises in the same way as above, a reservoir (6) able to contain a liquid, said reservoir (6) comprising an upper opening (7) for pouring said liquid into the reservoir (6), a screen (2) comprising a plurality of microscopic holes and a piezoelectric device (1) in contact with the liquid contained in the reservoir (6).
- Said reservoir (6) comprises a frustoconical lower portion (6a) whose smallest base forms the lower opening which is closed by the sieve (2) maintained on the lower face of said reservoir (6) in line with said lower opening by a lower cylindrical part (3).
- the upper part (6b) of the reservoir is substantially cylindrical.
- the piezoelectric device (1) consists of a vertical piezoelectric cylinder extending inside the frustoconical lower part (6a) of the reservoir (6), at the sieve (2) and perpendicular to said sieve (2). ).
- the lower end of said piezoelectric cylinder (1) extends at a maximum distance of 2 mm from said screen (2) and the axis of the piezoelectric cylinder (1) is substantially coaxial with the axis of revolution of the lower part. (6a) of the reservoir (6).
- the piezoelectric cylinder (1) is powered by an electrical signal by means of two pins (4) and (5) which extend above the lower part (6a) of the tank (6), along the side wall of the cylindrical upper portion (6b) of said reservoir (6).
- This variant of execution differs from those previously described in that it comprises a patient interface (14).
- the lower cylindrical part (3) is integral with the upper wall of the interface (14) which consists of a container (15) comprising a bottom wall (16), at least one side wall (17), an upper wall (18), and a mouthpiece (19), said lower cylindrical piece (3) opening into the container (15) whose upper wall is provided with a vent (20).
- the mouthpiece (19) may be substituted by a nosepiece or a face mask without departing from the scope of the invention.
- This alternative embodiment allows the oral or naso-oral administration of the aerosol.
- the generation of the aerosol is performed from top to bottom by the sieve (2) and the aerosol is produced in the interface (14).
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Special Spraying Apparatus (AREA)
Abstract
Description
Claims
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1459553A FR3026646B1 (en) | 2014-10-06 | 2014-10-06 | FIXED TAMIS NEBULIZATION DEVICE |
PCT/FR2015/052665 WO2016055723A1 (en) | 2014-10-06 | 2015-10-05 | Nebulizer with stationary screen |
Publications (1)
Publication Number | Publication Date |
---|---|
EP3204096A1 true EP3204096A1 (en) | 2017-08-16 |
Family
ID=52423842
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP15788144.2A Ceased EP3204096A1 (en) | 2014-10-06 | 2015-10-05 | Nebulizer with stationary screen |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP3204096A1 (en) |
FR (1) | FR3026646B1 (en) |
WO (1) | WO2016055723A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110419786A (en) * | 2019-08-29 | 2019-11-08 | 深圳爱芯怡科技有限公司 | Supersonic atomizer |
Family Cites Families (14)
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JPH08196965A (en) | 1995-01-31 | 1996-08-06 | Omron Corp | Ultrasonic atomizer |
IL116628A0 (en) * | 1995-12-31 | 1996-03-31 | Bronstein Rafael | A miniature multichannel piezoelectric pumping apparatus and methods of microdosing infusion introduction and inhalation |
US6530370B1 (en) * | 1999-09-16 | 2003-03-11 | Instrumentation Corp. | Nebulizer apparatus |
US7600511B2 (en) * | 2001-11-01 | 2009-10-13 | Novartis Pharma Ag | Apparatus and methods for delivery of medicament to a respiratory system |
US6948491B2 (en) * | 2001-03-20 | 2005-09-27 | Aerogen, Inc. | Convertible fluid feed system with comformable reservoir and methods |
JP2003102837A (en) | 2001-09-28 | 2003-04-08 | Omron Corp | Suction auxiliary implement for atomizer and atomizer having the same |
TWI242468B (en) * | 2004-06-14 | 2005-11-01 | Ind Tech Res Inst | Apparatus for generating micro-droplets |
JP4215765B2 (en) | 2005-09-26 | 2009-01-28 | 株式会社東芝 | Optical disc apparatus and tilt control method |
US7810743B2 (en) * | 2006-01-23 | 2010-10-12 | Kimberly-Clark Worldwide, Inc. | Ultrasonic liquid delivery device |
DE102006030833A1 (en) | 2006-07-04 | 2008-01-10 | Pari GmbH Spezialisten für effektive Inhalation | Method and device for cleaning the nebuliser membrane in an inhalation therapy device |
US20080271732A1 (en) * | 2007-05-01 | 2008-11-06 | Next Safety, Inc. | Pulmonary Drug Delivery Devices Configured to Control the Size of Administered Droplets |
JP5279740B2 (en) * | 2010-02-01 | 2013-09-04 | 三菱電機株式会社 | Ultrasonic atomizer and equipment equipped with the same |
FR2985909B1 (en) * | 2012-01-20 | 2014-08-08 | Diffusion Tech Francaise Sarl | NEBULIZATION DEVICE FOR MEDICAL AEROSOLS |
KR101466768B1 (en) * | 2013-02-27 | 2014-11-28 | 케이티메드 주식회사 | Nebulizer and housing for nebulizer |
-
2014
- 2014-10-06 FR FR1459553A patent/FR3026646B1/en active Active
-
2015
- 2015-10-05 WO PCT/FR2015/052665 patent/WO2016055723A1/en active Application Filing
- 2015-10-05 EP EP15788144.2A patent/EP3204096A1/en not_active Ceased
Non-Patent Citations (2)
Title |
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None * |
See also references of WO2016055723A1 * |
Also Published As
Publication number | Publication date |
---|---|
FR3026646B1 (en) | 2019-11-01 |
WO2016055723A1 (en) | 2016-04-14 |
FR3026646A1 (en) | 2016-04-08 |
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