EP3068288A4 - Systems and methods for determining lesion depth using fluorescence imaging - Google Patents

Systems and methods for determining lesion depth using fluorescence imaging Download PDF

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Publication number
EP3068288A4
EP3068288A4 EP14861958.8A EP14861958A EP3068288A4 EP 3068288 A4 EP3068288 A4 EP 3068288A4 EP 14861958 A EP14861958 A EP 14861958A EP 3068288 A4 EP3068288 A4 EP 3068288A4
Authority
EP
European Patent Office
Prior art keywords
systems
methods
fluorescence imaging
lesion depth
determining lesion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP14861958.8A
Other languages
German (de)
French (fr)
Other versions
EP3068288A2 (en
Inventor
Marco A. MERCADER
Narine SARVAZYAN
Terrance J. RANSBURY
Kenneth C. Armstrong
Omar Amirana
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
George Washington University
460Medical Inc
Original Assignee
George Washington University
LUXCATH LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by George Washington University, LUXCATH LLC filed Critical George Washington University
Priority claimed from PCT/US2014/065774 external-priority patent/WO2015073871A2/en
Publication of EP3068288A2 publication Critical patent/EP3068288A2/en
Publication of EP3068288A4 publication Critical patent/EP3068288A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/004—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • A61B5/0044—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the heart
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345—Vascular system
    • A61B2018/00351—Heart

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Cardiology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Endoscopes (AREA)
EP14861958.8A 2013-11-14 2014-11-14 Systems and methods for determining lesion depth using fluorescence imaging Pending EP3068288A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361904018P 2013-11-14 2013-11-14
PCT/US2014/065774 WO2015073871A2 (en) 2013-11-14 2014-11-14 Systems and methods for determining lesion depth using fluorescence imaging

Publications (2)

Publication Number Publication Date
EP3068288A2 EP3068288A2 (en) 2016-09-21
EP3068288A4 true EP3068288A4 (en) 2017-07-26

Family

ID=56682309

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14861958.8A Pending EP3068288A4 (en) 2013-11-14 2014-11-14 Systems and methods for determining lesion depth using fluorescence imaging

Country Status (2)

Country Link
EP (1) EP3068288A4 (en)
CN (2) CN112674861A (en)

Families Citing this family (12)

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Publication number Priority date Publication date Assignee Title
ES2727868T3 (en) 2011-09-22 2019-10-21 Univ George Washington Systems for visualizing ablated tissue
US9084611B2 (en) 2011-09-22 2015-07-21 The George Washington University Systems and methods for visualizing ablated tissue
JP6737705B2 (en) 2013-11-14 2020-08-12 ザ・ジョージ・ワシントン・ユニバーシティＴｈｅ Ｇｅｏｒｇｅ Ｗａｓｈｉｎｇｔｏｎｕｎｉｖｅｒｓｉｔｙ Method of operating system for determining depth of injury site and system for generating images of heart tissue
CN112674861A (en) * 2013-11-14 2021-04-20 乔治华盛顿大学 System and method for determining lesion depth using fluorescence imaging
WO2015077474A1 (en) 2013-11-20 2015-05-28 The George Washington University Systems and methods for hyperspectral analysis of cardiac tissue
EP3215002B1 (en) 2014-11-03 2024-03-20 The George Washington University Systems for lesion assessment
CN113208723A (en) 2014-11-03 2021-08-06 460医学股份有限公司 System and method for evaluation of contact quality
US10779904B2 (en) 2015-07-19 2020-09-22 460Medical, Inc. Systems and methods for lesion formation and assessment
US20180360342A1 (en) * 2017-06-16 2018-12-20 Biosense Webster (Israel) Ltd. Renal ablation and visualization system and method with composite anatomical display image
JP7165936B2 (en) 2018-04-13 2022-11-07 国立研究開発法人理化学研究所 TRAINING DEVICE, IMAGE PROCESSING METHOD, PROGRAM, AND INFORMATION RECORDING MEDIUM
CN109770853B (en) * 2019-01-30 2022-01-14 上海师范大学 Zebra fish wound detection method
WO2020174666A1 (en) * 2019-02-28 2020-09-03 オリンパス株式会社 Medical system

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US5074306A (en) * 1990-02-22 1991-12-24 The General Hospital Corporation Measurement of burn depth in skin
US6208886B1 (en) * 1997-04-04 2001-03-27 The Research Foundation Of City College Of New York Non-linear optical tomography of turbid media
JP2002500907A (en) * 1998-01-26 2002-01-15 マサチユセツツ・インスチチユート・オブ・テクノロジイ Endoscope for fluorescence imaging
US8900219B2 (en) * 1999-07-14 2014-12-02 Cardiofocus, Inc. System and method for visualizing tissue during ablation procedures
US8221402B2 (en) * 2000-01-19 2012-07-17 Medtronic, Inc. Method for guiding a medical device
US7400757B2 (en) * 2001-10-04 2008-07-15 Siemens Medical Solutions Usa, Inc. System and method for segmenting the left ventricle in a cardiac image
US6825928B2 (en) * 2001-12-19 2004-11-30 Wisconsin Alumni Research Foundation Depth-resolved fluorescence instrument
CN100998499B (en) * 2003-10-28 2013-07-24 薇拉莱特公司 Determination of a measure of a glycation end-product or disease state using tissue fluorescence
US7729750B2 (en) * 2005-01-20 2010-06-01 The Regents Of The University Of California Method and apparatus for high resolution spatially modulated fluorescence imaging and tomography
US20070100223A1 (en) * 2005-10-14 2007-05-03 Rui Liao Method and system for cardiac imaging and catheter guidance for radio frequency (RF) ablation
US8129105B2 (en) * 2006-04-13 2012-03-06 Ralph Zuckerman Method and apparatus for the non-invasive measurement of tissue function and metabolism by determination of steady-state fluorescence anisotropy
JP2007313169A (en) * 2006-05-29 2007-12-06 Olympus Corp Lesion extractor and lesion extraction method
CN101268945B (en) * 2007-03-22 2010-11-24 王靖中 On-site tridimensional footprint numeralization total processing system
US10219742B2 (en) * 2008-04-14 2019-03-05 Novadaq Technologies ULC Locating and analyzing perforator flaps for plastic and reconstructive surgery
US8948851B2 (en) * 2009-01-20 2015-02-03 The Trustees Of Dartmouth College Method and apparatus for depth-resolved fluorescence, chromophore, and oximetry imaging for lesion identification during surgery
CN101509871B (en) * 2009-03-25 2011-09-28 华中科技大学 Fluorescent molecular tomography method suitable for small animals
CN102184539B (en) * 2011-04-29 2013-10-30 王靖中 Image-processing-technology-based plane footprint detection and analysis system and method thereof
US9084611B2 (en) * 2011-09-22 2015-07-21 The George Washington University Systems and methods for visualizing ablated tissue
CN112674861A (en) * 2013-11-14 2021-04-20 乔治华盛顿大学 System and method for determining lesion depth using fluorescence imaging

Non-Patent Citations (2)

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Title
LUTHER MITCHELL SWIFT: "Real-Time Visualization of Cardiac Ablation Lesions Using Endogenous NADH Fluorescence and Reflected Light", SOUTHWESTERN UNIVERSITY M.S. IN MICROBIOLOGY, 23 July 2013 (2013-07-23), XP055381790, ISBN: 978-1-303-33207-4, Retrieved from the Internet <URL:http://search.proquest.com/docview/1436990880> [retrieved on 20170614] *
M. MERCADER ET AL: "Use of endogenous NADH fluorescence for real-time in situ visualization of epicardial radiofrequency ablation lesions and gaps", AMERICAN JOURNAL OF PHYSIOLOGY: HEART AND CIRCULATORY PHYSIOLOGY, vol. 302, no. 10, 9 March 2012 (2012-03-09), US, pages H2131 - H2138, XP055381470, ISSN: 0363-6135, DOI: 10.1152/ajpheart.01141.2011 *

Also Published As

Publication number Publication date
CN106028914B (en) 2020-09-15
CN106028914A (en) 2016-10-12
CN112674861A (en) 2021-04-20
EP3068288A2 (en) 2016-09-21

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