EP3049112A4 - Influenza vaccine and therapy - Google Patents

Influenza vaccine and therapy Download PDF

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Publication number
EP3049112A4
EP3049112A4 EP14845566.0A EP14845566A EP3049112A4 EP 3049112 A4 EP3049112 A4 EP 3049112A4 EP 14845566 A EP14845566 A EP 14845566A EP 3049112 A4 EP3049112 A4 EP 3049112A4
Authority
EP
European Patent Office
Prior art keywords
therapy
influenza vaccine
influenza
vaccine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP14845566.0A
Other languages
German (de)
French (fr)
Other versions
EP3049112A1 (en
EP3049112B1 (en
Inventor
Mark Alfenito
Mark Baer
Doris BUCHER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Engen Bio LLC
Original Assignee
ENGEN BIO Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ENGEN BIO Inc filed Critical ENGEN BIO Inc
Publication of EP3049112A1 publication Critical patent/EP3049112A1/en
Publication of EP3049112A4 publication Critical patent/EP3049112A4/en
Application granted granted Critical
Publication of EP3049112B1 publication Critical patent/EP3049112B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6081Albumin; Keyhole limpet haemocyanin [KLH]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP14845566.0A 2013-09-23 2014-09-21 Influenza vaccine and therapy Active EP3049112B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361881325P 2013-09-23 2013-09-23
PCT/US2014/056703 WO2015042498A1 (en) 2013-09-23 2014-09-21 Influenza vaccine and therapy

Publications (3)

Publication Number Publication Date
EP3049112A1 EP3049112A1 (en) 2016-08-03
EP3049112A4 true EP3049112A4 (en) 2017-07-12
EP3049112B1 EP3049112B1 (en) 2020-09-09

Family

ID=52689487

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14845566.0A Active EP3049112B1 (en) 2013-09-23 2014-09-21 Influenza vaccine and therapy

Country Status (11)

Country Link
US (1) US9999662B2 (en)
EP (1) EP3049112B1 (en)
JP (1) JP6877143B2 (en)
KR (1) KR20160055825A (en)
CN (1) CN104436157A (en)
AU (1) AU2014321314A1 (en)
BR (1) BR112016006210A2 (en)
CA (1) CA2923226A1 (en)
ES (1) ES2833156T3 (en)
IL (1) IL244354B (en)
WO (1) WO2015042498A1 (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6262969B2 (en) * 2013-09-10 2018-01-17 デンカ生研株式会社 Method for measuring influenza A virus
US10080792B2 (en) 2013-09-23 2018-09-25 Engen Bio, Inc. Influenza vaccine and therapy
CN104436157A (en) 2013-09-23 2015-03-25 恩金生物有限公司 Influenza vaccine and therapy
WO2016168835A1 (en) * 2015-04-17 2016-10-20 South Dakota Board Of Regents Compositions and methods for vaccination against influenza a virus
CA2999596C (en) * 2015-09-23 2023-10-03 Dectronique (1984) Inc. Electronic vision system and use thereof
JP6782218B2 (en) * 2017-11-17 2020-11-11 株式会社東芝 Detection device and detection method
CN110680912B (en) * 2019-09-26 2021-08-17 中国农业大学 H3N2 and H3N8 subtype canine influenza bivalent inactivated vaccine as well as preparation method and application thereof

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See also references of WO2015042498A1 *

Also Published As

Publication number Publication date
KR20160055825A (en) 2016-05-18
CN104436157A (en) 2015-03-25
CA2923226A1 (en) 2015-03-26
JP6877143B2 (en) 2021-05-26
IL244354A0 (en) 2016-04-21
AU2014321314A1 (en) 2016-03-17
BR112016006210A2 (en) 2017-09-26
ES2833156T3 (en) 2021-06-14
EP3049112A1 (en) 2016-08-03
US20150086560A1 (en) 2015-03-26
US9999662B2 (en) 2018-06-19
IL244354B (en) 2021-12-01
JP2016531934A (en) 2016-10-13
WO2015042498A1 (en) 2015-03-26
EP3049112B1 (en) 2020-09-09

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