EP2951321A4 - Synthesis and enrichment of nucleic acid sequences - Google Patents

Synthesis and enrichment of nucleic acid sequences

Info

Publication number
EP2951321A4
EP2951321A4 EP14861883.8A EP14861883A EP2951321A4 EP 2951321 A4 EP2951321 A4 EP 2951321A4 EP 14861883 A EP14861883 A EP 14861883A EP 2951321 A4 EP2951321 A4 EP 2951321A4
Authority
EP
European Patent Office
Prior art keywords
enrichment
synthesis
nucleic acid
acid sequences
sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14861883.8A
Other languages
German (de)
French (fr)
Other versions
EP2951321A2 (en
Inventor
Jason Poole
Saege Hancock
Karena Kosco
Vlada Melnikova
Peter Croucher
Tim Lu
Mark G Erlander
Errin Samuelsz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cardiff Oncology Inc
Original Assignee
Trovagene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trovagene Inc filed Critical Trovagene Inc
Priority claimed from PCT/US2014/061435 external-priority patent/WO2015073163A2/en
Publication of EP2951321A2 publication Critical patent/EP2951321A2/en
Publication of EP2951321A4 publication Critical patent/EP2951321A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP14861883.8A 2013-10-20 2014-10-20 Synthesis and enrichment of nucleic acid sequences Withdrawn EP2951321A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361893283P 2013-10-20 2013-10-20
US201361904141P 2013-11-14 2013-11-14
US201462039905P 2014-08-20 2014-08-20
PCT/US2014/061435 WO2015073163A2 (en) 2013-11-14 2014-10-20 Synthesis and enrichment of nucleic acid sequences

Publications (2)

Publication Number Publication Date
EP2951321A2 EP2951321A2 (en) 2015-12-09
EP2951321A4 true EP2951321A4 (en) 2016-11-09

Family

ID=54361247

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14861883.8A Withdrawn EP2951321A4 (en) 2013-10-20 2014-10-20 Synthesis and enrichment of nucleic acid sequences

Country Status (2)

Country Link
EP (1) EP2951321A4 (en)
HK (1) HK1211628A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012075231A1 (en) * 2010-12-03 2012-06-07 Brandeis University Methods and kits for detecting nucleic acid mutants in wild-type populations
WO2012162613A2 (en) * 2011-05-26 2012-11-29 Brandeis University Detection of sequence variants in the human epidermal growth factor receptor (egfr) gene

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012075231A1 (en) * 2010-12-03 2012-06-07 Brandeis University Methods and kits for detecting nucleic acid mutants in wild-type populations
WO2012162613A2 (en) * 2011-05-26 2012-11-29 Brandeis University Detection of sequence variants in the human epidermal growth factor receptor (egfr) gene

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JOHN MORLAN ET AL: "Mutation Detection by Real-Time PCR: A Simple, Robust and Highly Selective Method", PLOS ONE, vol. 4, no. 2, 25 February 2009 (2009-02-25), pages e4584, XP055111534, DOI: 10.1371/journal.pone.0004584 *
WANG HAIYING ET AL: "Allele-Specific, Non-Extendable Primer Blocker PCR (AS-NEPB-PCR) for DNA Mutation Detection in Cancer", JOURNAL OF MOLECULAR DIAGNOSTICS,THE, AMERICAN SOCIETY FOR INVESTIGATIVE PATHOLOGY, US, vol. 15, no. 1, 1 January 2013 (2013-01-01), pages 62 - 69, XP009166207, ISSN: 1525-1578, DOI: 10.1016/J.JMOLDX.2012.08.007 *

Also Published As

Publication number Publication date
EP2951321A2 (en) 2015-12-09
HK1211628A1 (en) 2016-05-27

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