EP2831283A4 - Procédés et composition permettant le séquençage d'acides nucléiques modifiés - Google Patents
Procédés et composition permettant le séquençage d'acides nucléiques modifiésInfo
- Publication number
- EP2831283A4 EP2831283A4 EP13769322.2A EP13769322A EP2831283A4 EP 2831283 A4 EP2831283 A4 EP 2831283A4 EP 13769322 A EP13769322 A EP 13769322A EP 2831283 A4 EP2831283 A4 EP 2831283A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- composition
- methods
- nucleic acids
- modified nucleic
- sequencing modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261617999P | 2012-03-30 | 2012-03-30 | |
US201261721339P | 2012-11-01 | 2012-11-01 | |
US201261721206P | 2012-11-01 | 2012-11-01 | |
US201361799237P | 2013-03-15 | 2013-03-15 | |
US201361789354P | 2013-03-15 | 2013-03-15 | |
PCT/US2013/032816 WO2013148400A1 (fr) | 2012-03-30 | 2013-03-18 | Procédés et composition permettant le séquençage d'acides nucléiques modifiés |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2831283A1 EP2831283A1 (fr) | 2015-02-04 |
EP2831283A4 true EP2831283A4 (fr) | 2015-11-04 |
Family
ID=49261113
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP13769322.2A Withdrawn EP2831283A4 (fr) | 2012-03-30 | 2013-03-18 | Procédés et composition permettant le séquençage d'acides nucléiques modifiés |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP2831283A4 (fr) |
AU (1) | AU2013240166A1 (fr) |
CA (1) | CA2867489A1 (fr) |
WO (1) | WO2013148400A1 (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9290800B2 (en) | 2013-03-15 | 2016-03-22 | Pacific Biosciences Of California, Inc. | Targeted rolling circle amplification |
US10048208B2 (en) * | 2013-11-17 | 2018-08-14 | Quantum-Si Incorporated | Integrated device with external light source for probing detecting and analyzing molecules |
US20170356028A1 (en) * | 2014-10-22 | 2017-12-14 | bis Biosciences, Inc. | Bacterial epigenomic analysis |
US9859394B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
US10006910B2 (en) | 2014-12-18 | 2018-06-26 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same |
US9857328B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems and methods for manufacturing and using the same |
US10020300B2 (en) | 2014-12-18 | 2018-07-10 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
US9618474B2 (en) | 2014-12-18 | 2017-04-11 | Edico Genome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
US10429342B2 (en) | 2014-12-18 | 2019-10-01 | Edico Genome Corporation | Chemically-sensitive field effect transistor |
WO2017201081A1 (fr) | 2016-05-16 | 2017-11-23 | Agilome, Inc. | Dispositifs à fet au graphène, systèmes et leurs méthodes d'utilisation pour le séquençage d'acides nucléiques |
CN109313925B (zh) * | 2016-06-01 | 2022-09-02 | 宽腾矽公司 | 脉冲命名器及基质命名器 |
EP3366780B1 (fr) * | 2017-02-23 | 2020-05-06 | Siemens Healthcare GmbH | Analyse de séquence de molécules individuelles et de méthylation à très haute sensibilité pour analyse spécifique de tissus |
EP3704265A4 (fr) * | 2017-11-03 | 2021-09-29 | Guardant Health, Inc. | Correction d'erreurs de séquence induites par désamination |
WO2019147904A1 (fr) | 2018-01-26 | 2019-08-01 | Quantum-Si Incorporated | Appel de bases et d'impulsions activé par apprentissage automatique pour dispositifs de séquençage |
CN112534063A (zh) | 2018-05-22 | 2021-03-19 | 安序源有限公司 | 用于核酸测序的方法、***和组合物 |
TW202400809A (zh) * | 2022-03-17 | 2024-01-01 | 美商再生元醫藥公司 | 利用鹼基修飾來表徵病毒基因組的方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008154317A1 (fr) * | 2007-06-06 | 2008-12-18 | Pacific Biosciences Of California, Inc. | Méthodes et procédés pour identifier des bases dans des procédés d'incorporation en fonction de la séquence |
WO2009145818A1 (fr) * | 2008-03-31 | 2009-12-03 | Pacific Biosciences Of California, Inc | Procédés et compositions de charge de molécule individuelle |
WO2010068289A2 (fr) * | 2008-12-11 | 2010-06-17 | Pacific Biosciences Of California, Inc. | Classification de matrices d'acides nucléiques |
US20110183320A1 (en) * | 2008-12-11 | 2011-07-28 | Pacific Biosciences Of California, Inc. | Classification of nucleic acid templates |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU7516694A (en) | 1993-07-30 | 1995-02-28 | Affymax Technologies N.V. | Biotinylation of proteins |
US5795782A (en) | 1995-03-17 | 1998-08-18 | President & Fellows Of Harvard College | Characterization of individual polymer molecules based on monomer-interface interactions |
DE69928265T3 (de) | 1998-07-30 | 2013-11-28 | Illumina Cambridge Ltd. | Matrizen von biomolekülen und ihre verwendung in sequenzierung |
US7056661B2 (en) | 1999-05-19 | 2006-06-06 | Cornell Research Foundation, Inc. | Method for sequencing nucleic acid molecules |
US6917726B2 (en) | 2001-09-27 | 2005-07-12 | Cornell Research Foundation, Inc. | Zero-mode clad waveguides for performing spectroscopy with confined effective observation volumes |
US7670405B2 (en) | 2003-08-06 | 2010-03-02 | Department Of Science & Technology (Dst) | Process for the manufacture of a bio-release fertilizer of an anionic micro nutrient viz molybdenum |
US20060046258A1 (en) * | 2004-02-27 | 2006-03-02 | Lapidus Stanley N | Applications of single molecule sequencing |
US7399614B2 (en) | 2004-06-30 | 2008-07-15 | Applera Corporation | 5-methylcytosine detection, compositions and methods therefor |
US7170050B2 (en) | 2004-09-17 | 2007-01-30 | Pacific Biosciences Of California, Inc. | Apparatus and methods for optical analysis of molecules |
CN101914620B (zh) | 2004-09-17 | 2014-02-12 | 加利福尼亚太平洋生命科学公司 | 核酸测序的方法 |
US7805081B2 (en) | 2005-08-11 | 2010-09-28 | Pacific Biosciences Of California, Inc. | Methods and systems for monitoring multiple optical signals from a single source |
US7405281B2 (en) | 2005-09-29 | 2008-07-29 | Pacific Biosciences Of California, Inc. | Fluorescent nucleotide analogs and uses therefor |
CA2622872A1 (fr) | 2005-09-30 | 2007-04-12 | Pacific Biosciences Of California, Inc. | Surfaces reactives, substrats et procedes de production et d'utilisation correspondants |
US7998717B2 (en) | 2005-12-02 | 2011-08-16 | Pacific Biosciences Of California, Inc. | Mitigation of photodamage in analytical reactions |
CN101365807A (zh) | 2005-12-22 | 2009-02-11 | 加利福尼亚太平洋生物科学股份有限公司 | 用于掺入核苷酸类似物的聚合酶 |
EP3936857B1 (fr) | 2006-09-01 | 2023-06-21 | Pacific Biosciences Of California, Inc. | Substrats, systèmes et procédés d'analyse de matériaux |
US20080277595A1 (en) | 2007-05-10 | 2008-11-13 | Pacific Biosciences Of California, Inc. | Highly multiplexed confocal detection systems and methods of using same |
US7901889B2 (en) | 2007-07-26 | 2011-03-08 | Pacific Biosciences Of California, Inc. | Molecular redundant sequencing |
CA2715385A1 (fr) | 2008-02-12 | 2009-08-20 | Pacific Biosciences Of California, Inc. | Compositions et procedes utilisables dans des reactions analytiques |
US8652781B2 (en) | 2008-02-12 | 2014-02-18 | Pacific Biosciences Of California, Inc. | Cognate sampling kinetics |
EP2263087B1 (fr) | 2008-03-13 | 2017-08-09 | Pacific Biosciences of California, Inc. | Réactifs marqués et leurs utilisations |
US7973146B2 (en) | 2008-03-26 | 2011-07-05 | Pacific Biosciences Of California, Inc. | Engineered fluorescent dye labeled nucleotide analogs for DNA sequencing |
WO2009120374A2 (fr) | 2008-03-28 | 2009-10-01 | Pacific Biosciences Of California, Inc. | Procédés et compositions pour la préparation d’échantillon d’acide nucléique |
BRPI0909212A2 (pt) | 2008-03-28 | 2015-08-18 | Pacific Biosciences California | Composições e método para sequeciamento de ácido nucléico |
EP2271751B1 (fr) | 2008-03-31 | 2015-07-22 | Pacific Biosciences of California, Inc. | Génération de polymérases modifiées pour une précision améliorée dans le séquençage d'une seule molécule |
AU2009292629B2 (en) | 2008-09-16 | 2014-03-20 | Pacific Biosciences Of California, Inc. | Substrates and optical systems and methods of use thereof |
US8481264B2 (en) | 2008-09-19 | 2013-07-09 | Pacific Biosciences Of California, Inc. | Immobilized nucleic acid complexes for sequence analysis |
WO2010036287A1 (fr) | 2008-09-24 | 2010-04-01 | Pacific Biosciences Of California, Inc. | Détection intermittente durant des réactions analytiques |
US8370079B2 (en) | 2008-11-20 | 2013-02-05 | Pacific Biosciences Of California, Inc. | Algorithms for sequence determination |
JP5439822B2 (ja) | 2009-01-15 | 2014-03-12 | 独立行政法人物質・材料研究機構 | Ni基単結晶超合金 |
US9017937B1 (en) | 2009-04-10 | 2015-04-28 | Pacific Biosciences Of California, Inc. | Nanopore sequencing using ratiometric impedance |
EP2425023B1 (fr) | 2009-04-27 | 2015-12-23 | Pacific Biosciences of California, Inc. | Procédés et systèmes de séquençage en temps réel |
CA2790434A1 (fr) * | 2010-02-18 | 2011-08-25 | Anthony P. Shuber | Compositions et methodes pour le traitement du cancer |
US20130138358A1 (en) | 2010-02-24 | 2013-05-30 | Pacific Biosciences Of California, Inc. | Algorithms for sequence determination |
US9165109B2 (en) | 2010-02-24 | 2015-10-20 | Pacific Biosciences Of California, Inc. | Sequence assembly and consensus sequence determination |
-
2013
- 2013-03-18 AU AU2013240166A patent/AU2013240166A1/en not_active Abandoned
- 2013-03-18 EP EP13769322.2A patent/EP2831283A4/fr not_active Withdrawn
- 2013-03-18 CA CA2867489A patent/CA2867489A1/fr not_active Abandoned
- 2013-03-18 WO PCT/US2013/032816 patent/WO2013148400A1/fr active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008154317A1 (fr) * | 2007-06-06 | 2008-12-18 | Pacific Biosciences Of California, Inc. | Méthodes et procédés pour identifier des bases dans des procédés d'incorporation en fonction de la séquence |
WO2009145818A1 (fr) * | 2008-03-31 | 2009-12-03 | Pacific Biosciences Of California, Inc | Procédés et compositions de charge de molécule individuelle |
WO2010068289A2 (fr) * | 2008-12-11 | 2010-06-17 | Pacific Biosciences Of California, Inc. | Classification de matrices d'acides nucléiques |
US20110183320A1 (en) * | 2008-12-11 | 2011-07-28 | Pacific Biosciences Of California, Inc. | Classification of nucleic acid templates |
Non-Patent Citations (4)
Title |
---|
BENJAMIN FLUSBERG: "Direct detection of DNA methylation and mutagenic damage through single-molecule, real-time (SMRT (TM)) DNA sequencing", 101ST ANNUAL MEETING OF THE AMERICAN-ASSOCIATION-FOR-CANCER-RESEARCH; WASHINGTON, DC, USA; APRIL 17 -21, 2010, 1 April 2010 (2010-04-01), XP055215735, Retrieved from the Internet <URL:http://www.abstractsonline.com/Plan/ViewAbstract.aspx?mID=2521&sKey=ad61b071-5ab9-4f64-bf00-14f780960c07&cKey=68c67e8a-73b3-4b54-8a51-7bc1e5ae1748&mKey=0591fa3b-afef-49d2-8e65-55f41ee8117e> [retrieved on 20150923] * |
FLUSBERG BENJAMIN A ET AL: "Direct detection of DNA methylation during single-molecule, real-time sequencing", NATURE METHODS, NATURE PUBLISHING GROUP, GB, vol. 7, no. 6, 1 July 2010 (2010-07-01), pages 461 - 465, XP009142171, ISSN: 1548-7105, [retrieved on 20100509], DOI: 10.1038/NMETH.1459 * |
See also references of WO2013148400A1 * |
THOMPSON JOHN F ET AL: "The properties and applications of single-molecule DNA sequencing", GENOME BIOLOGY, BIOMED CENTRAL LTD., LONDON, GB, vol. 12, no. 2, 24 February 2011 (2011-02-24), pages 217, XP021091788, ISSN: 1465-6906 * |
Also Published As
Publication number | Publication date |
---|---|
AU2013240166A1 (en) | 2014-10-30 |
WO2013148400A1 (fr) | 2013-10-03 |
CA2867489A1 (fr) | 2013-10-03 |
EP2831283A1 (fr) | 2015-02-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 20141013 |
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AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
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AX | Request for extension of the european patent |
Extension state: BA ME |
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DAX | Request for extension of the european patent (deleted) | ||
RA4 | Supplementary search report drawn up and despatched (corrected) |
Effective date: 20151002 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12Q 1/68 20060101AFI20150928BHEP Ipc: G01N 33/48 20060101ALI20150928BHEP |
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17Q | First examination report despatched |
Effective date: 20161207 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 20180220 |