EP2789389B1 - Dispositif pour stockage et pour fournir des embouts de pipette - Google Patents
Dispositif pour stockage et pour fournir des embouts de pipette Download PDFInfo
- Publication number
- EP2789389B1 EP2789389B1 EP13001900.3A EP13001900A EP2789389B1 EP 2789389 B1 EP2789389 B1 EP 2789389B1 EP 13001900 A EP13001900 A EP 13001900A EP 2789389 B1 EP2789389 B1 EP 2789389B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- carrier
- pipette tips
- sidewalls
- rib
- side walls
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000001681 protective effect Effects 0.000 claims description 19
- 239000004033 plastic Substances 0.000 claims description 10
- 229920003023 plastic Polymers 0.000 claims description 10
- 239000011324 bead Substances 0.000 claims description 9
- 230000002093 peripheral effect Effects 0.000 claims description 2
- 238000006073 displacement reaction Methods 0.000 description 14
- 238000001746 injection moulding Methods 0.000 description 10
- 239000007788 liquid Substances 0.000 description 7
- 238000003780 insertion Methods 0.000 description 6
- 230000037431 insertion Effects 0.000 description 6
- 238000013461 design Methods 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 239000004743 Polypropylene Substances 0.000 description 3
- 239000000969 carrier Substances 0.000 description 3
- 229920001155 polypropylene Polymers 0.000 description 3
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 238000013459 approach Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 238000007373 indentation Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
Images
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/54—Supports specially adapted for pipettes and burettes
- B01L9/543—Supports specially adapted for pipettes and burettes for disposable pipette tips, e.g. racks or cassettes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0275—Interchangeable or disposable dispensing tips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/025—Align devices or objects to ensure defined positions relative to each other
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/08—Ergonomic or safety aspects of handling devices
- B01L2200/087—Ergonomic aspects
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/02—Identification, exchange or storage of information
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/043—Hinged closures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0858—Side walls
Definitions
- the invention relates to a device for providing pipette tips.
- Pipette tips are small plastic tubes that are used in the laboratory for dosing liquid samples, preferably in the range of 0.1 microliter to 100 ml. They have a lower passage for liquid and an upper passage for air, wherein the cross section of the pipette tips usually increases from the lower to the upper passage opening.
- the top of the pipette tip is connected to a pipette so that the top port is connected to a pipette air displacement device.
- the pipette tip is clamped with the passage opening on a neck of the pipette or clamped in a hole of the pipette.
- the displacement device is a cylinder with a piston displaceable therein.
- the metered amount of liquid depends on the displacement of the displacement device.
- Fixed volume pipettes with a constant dosing volume have a constant displacement and variable pipettes with adjustable dosing volume have an adjustable displacement.
- the pipette tip is separated from its seat on the pipette, for which the pipette may have an ejector which, when actuated, forces the pipette tip off its seat. Thereafter, the pipette can pick up a new pipette tip. Carryover of sample liquid between successive dosages is thus avoided.
- pipette tips are provided on pipette tip supply devices. These devices have a plate-shaped support with a substantially rectangular base made of plastic, also called “tray” or “wafer”, with a plurality of holes in a matrix arrangement on.
- the perforated plate usually has 96 holes in eight rows and twelve columns. Pipette tips are inserted into the holes from above, but do not fall through the holes due to an upwardly broadening diameter or a collar at their upper end.
- these devices comprise a lower part, which is designed as a box closed at the bottom and open at the top (also called a “box”) or at the bottom and at the top, a rectangular frame (also called a "rack").
- a carrier equipped with pipette tips can be placed on means for supporting on the upper edge of the lower part, so that the pipette tips and the carrier protrude into a receptacle in the lower part.
- Known devices for providing pipette tips have on two opposite narrow sides of the carrier in each case a gripping tab, which are connected to the lower edge of the narrow side of the carrier, have an operating end above and between a on the outside has a locking bead, which with a locking projection on the Inside a side wall of the lower part is locked.
- the narrow sides are the two long sides and the two short sides of the rectangular support.
- the pipette tips are removable by pressing the seat of a single-channel pipette or the seats of a multichannel pipette onto or into the upper ends of the pipette tips individually or simultaneously to several of a pipette tip supply apparatus.
- the latched grip tabs prevent the wearer from being inadvertently lifted when removing pipette tips with a pipette.
- the lower part can be equipped with refill packs with fresh pipette tips.
- the refill packs include one or more plate-shaped carriers that are equipped with pipette tips.
- refill packages are known in which one or more carriers equipped with pipette tips are arranged in folding boxes or frames made of cardboard or in simple plastic boxes or plastic frames.
- the user To load the base with a carrier with pipette tips from a refill pack, the user must align the new carrier exactly onto the top opening of the base and lower it with the pipette tips into the receptacle until the grip tabs lock into place with the bottom part.
- the correct alignment of the carrier with the pipette tips on the lower part and finding the detent position is cumbersome. This can lead to entanglements that interfere with the process and thwart finding the detent position. If the carrier is not locked to the base, the carrier can be lifted when receiving pipette tips, with the result that pipette tips can fall out.
- Another disadvantage is that the user product information that are attached to one or more narrow sides of the carrier can not read when the carrier is locked to the lower part, since the side walls of the lower part cover the narrow sides.
- the user To read the product information, the user must release the catch and lift the carrier. If the product information e.g. are placed on a label on the outside of the base, there is no guarantee that these will apply to refilled pipette tips, because of the possibility that other types of pipette tips have been refilled.
- EP 2333559 discloses an apparatus for providing pipette tips.
- the object of the invention is to provide a device for providing pipette tips, which facilitates the insertion of a carrier with pipette tips and the readability of product information on the narrow sides of the carrier.
- the device according to the invention has in each case at least one vertically extending recess in the outer sides of two mutually opposite narrow sides of the plate-shaped support.
- the recess is a vertical recess in a narrow side of the carrier.
- the narrow sides of the plate-shaped carrier are those sides of the carrier which connect the large-area upper and lower sides of the carrier at the edge.
- the plate-shaped carrier preferably has a rectangular shape and the narrow sides are two longitudinal sides and two transverse sides of the carrier.
- the device has a lower part, which has two opposing first side walls, which project further upwards from a standing surface, than two opposing second side walls. On the inner sides of at least two opposing side walls there are means for supporting the carrier in a horizontal orientation.
- the two first side walls each have two spaced-apart vertical guide ribs.
- the recesses of the carrier and the guide ribs of the lower part are matched to each other, so that the guide ribs at least partially engage in the recesses when the carrier is placed on the means for supporting.
- the carrier is circumferentially framed by the side walls of the base, because the carrier touches below the upper edges of all the side walls on the means for supporting.
- To put on the Means for supporting the carrier must be aligned with its recesses correctly on the guide ribs. If the carrier with the recesses is not correctly aligned with the guide ribs, the guide ribs prevent the carrier from being lowered onto the support means.
- the upper ends of the guide ribs are bearing points on which the carrier is displaceable in the horizontal direction parallel to the first side walls until the guide ribs are correctly aligned with the recesses and enter into these.
- the fact that the carrier is supported on the two first side walls of two guide ribs a non-tilting horizontal mounting of the carrier is possible if it is not aligned exactly with the receptacle of the base.
- the carrier is placed with adjacent to the recesses lower edges in a horizontal orientation on the upper ends of the guide ribs. This mounting of the carrier may be assisted by seating the carrier on an upper edge of a second side wall of the base when the upper edge of the second side wall is located at the same height as the upper ends of the guide ribs.
- the rib width of 2.5mm to 4mm each and the rib height of 2.5mm to 4mm each ensure that the carrier slides well on the upper ends of the guide ribs.
- the ribs do not impose a high frictional resistance on the horizontal displacement of the carrier and do not catch on the lower edge of the carrier.
- the dimensions of the guide ribs ensure that they can be produced by injection molding with low material costs and do not break under load by placing the carrier.
- the rib height promotes carriers whose dimensions in the direction parallel to the second side walls are significantly less than the distance between the inner sides of the first side walls, whereby the insertion of the carrier is further facilitated in the recording.
- the dimension of the guide rib in the horizontal direction is parallel to the first side walls, and with the rib height, the dimension of the guide rib in the horizontal direction is perpendicular to the first side walls.
- the second side walls allow for a horizontal displacement of the carrier on the guide ribs and with its edge regions above the second side walls due to their lower height than the first side walls until the pipette tips come to rest on the inner sides of the second side walls. This facilitates the insertion of the loaded with pipette tips carrier in the recording. Subsequently, the carrier can be aligned by horizontal displacement with the recesses on the guide ribs.
- the user can product information on the parallel to the second side walls long sides of the Read carrier, even if the carrier is inserted into the receptacle of the lower part.
- the product information may, for example, designate the fill volume and / or the type of pipette tip.
- the invention thus facilitates the insertion of the carrier equipped with pipette tips in the lower part.
- two opposite longitudinal sides of the carrier can be used as a carrier for product information, which are also legible when the carrier is inserted into the lower part.
- the base is preferably a box closed at the bottom by a bottom wall from which the side walls are raised.
- the footprint may be formed from the underside of the bottom wall or through the underside of feet that protrude downwardly with respect to the bottom wall.
- the lower part is a frame formed by the side walls.
- the footprint may be formed by the lower edges of the sidewalls or the underside of feet projecting downwardly from the sidewalls.
- each guide rib is formed of a group having at least two parallel rib members, each rib member having a width of 0.50mm to 1.5mm and the spacing between the rib members of a group being 0.5mm to 1.5mm.
- the recesses in at least one narrow side of the carrier are two spaced-apart vertical grooves with a groove width of 2.5 mm to 4.5 mm. Due to the two spaced-apart grooves, the carrier is only slightly weakened in the region of the narrow sides, so that it has a high stability.
- at least one narrow side of the carrier has a single recess in the form of a vertical groove which receives both guide ribs.
- the at least one recess in at least one narrow side of the carrier is delimited at its outer edge by a skirting board extending along the lower edge of the carrier and projecting outwards. The skirting board can be used to attach a protective hood, which protrudes laterally beyond the carrier.
- the carrier with the attached protective cover can be used in a lower part, whereby the protective cover protects the pipette tips against contamination.
- the at least one recess in at least one narrow side is bounded at its inner edge by a gripping tab, which is connected at the bottom to the lower edge of the narrow side of the carrier and extends at a distance from the narrow side up to beyond the first side walls ,
- the grip tab facilitates insertion and removal of the carrier from the base.
- the carrier can be supported by the grip tab on the inner sides of the first side walls in order to keep the carrier in a defined position in the lower part.
- two spaced-apart vertical grooves are bounded in at least one narrow side at its outer edge by outwardly projecting baseboards and at its inner edge by a gripping tab.
- the invention incorporates alternative embodiments in which two spaced vertical recesses in at least one narrow side are bounded at their inner edges by the gripping tab and extend outwardly to the adjacent longitudinal sides of the carrier.
- At least one gripping tab on its outer side has a first means for latching, which is latched with a second means for locking on the inside of the first side wall.
- the carrier is releasably connectable to the base to prevent inadvertent withdrawal of the support in the removal of pipette tips. To replace the carrier is unlocked by pressing the grip tabs.
- the carrier has a horizontal top wall with holes arranged therein and a circumferential skirt projecting downwardly from the lateral edges of the top wall.
- the design is material-saving and stable produced by injection molding.
- the skirt outside the recesses on an outwardly projecting, the baseboard forming lower portion is material-saving and stable produced by injection molding.
- the edges of the holes are connected to sleeves projecting from the underside of the top wall into which the pipette tips are inserted.
- the grip tabs are strip-shaped and have first means for latching in the form of at least one outwardly projecting, horizontal bead. As a result, a material-saving production of the carrier by injection molding is further promoted.
- the means for supporting vertical ribs projecting from the inner sides of the side walls This also favors a material-saving producible by injection molding, stable design of the lower part.
- the first and the second side walls each have a plurality of means for supporting.
- the ribs have a rib width of preferably 0.5 mm to 1.5 mm, in particular of 1.0 mm.
- the means for supporting at least partially on their inner edges projecting projections with outwardly inclined chamfers on the outer sides, which engage behind the apron of the carrier inside.
- the bevels may pull the apron of the wearer outwardly to bring the wearer into a correct shape, as the skirt may tend to deflect slightly inwardly, particularly in low wall thickness designs.
- a protective hood is placed on top of the carrier and covers the pipette tips inserted into the holes. Through the protective cover, the pipette tips are protected when transferring the carrier from a supply pack into the lower part.
- the lower part has a pivotally mounted lid, which in the closed position, the receptacle together with an inserted carrier and, if necessary, the protective patch patch cover and is pivotable in an open position in which the carrier with the pipette tips and if necessary. Patch guard can be removed from the lower part and used in this and pipette tips can be removed from the carrier.
- the carrier and / or the lower part and / or the protective hood and / or the cover is made of a plastic.
- the same or different plastics can be used.
- the production of all components or of individual components by injection molding.
- top and bottom and “vertical” and “horizontal” refer to an arrangement of the device in which the plate-shaped support is oriented horizontally, the base sits with the footprint on a horizontal surface and the Carrier is inserted from above into the lower part.
- the inventive device 1 for providing pipette tips comprises a substantially plate-shaped and substantially rectangular carrier 2, which is equipped with pipette tips 3. Furthermore, the device 1 comprises a substantially box-shaped lower part 4, in which the carrier 2 with the pipette tips 3 is inserted. In addition, the device 1 according to Fig. 11 to 16 a protective cover 5 which can be placed on the support and a cover 6 pivotally connected to the lower part 4.
- the carrier 2 comprises a substantially rectangular top wall 7, which has chamfers 8 at the four corners.
- the top wall 7 has in eight rows and twelve columns a total of 96 circular holes 9, which are aligned perpendicular to the top wall 7.
- the holes 9 are dimensioned such that pipette tips 3 of a specific size and shape can be inserted therein and held in the carrier 2 due to an expansion of their outer diameter towards the upper end, without falling through the holes 9.
- the pipette tips 3 may have a continuously widening from the lower end to the upper end diameter or a sudden increase in the outer diameter.
- the carrier 2 has an approximately vertically upwardly projecting, circumferential skirt 11, which is connected at the top to the lateral edges of the top wall 7.
- the Apron 11 has below an outwardly projecting, a skirting 12 forming lower portion.
- the skirt is provided at its upper portion 13 and in the region of the baseboard 12 also at the corners with chamfers 14, 15.
- the base area of the carrier 2 essentially corresponds to the base area of a microtiter plate and the arrangement of the holes 9 essentially corresponds to the arrangement of the wells of a 96-well microtiter plate according to the ANSI standard on the recommendation of the Society for Biomolecular Screening (SBS).
- SBS Society for Biomolecular Screening
- the carrier 2 thus has two short narrow sides 16, 17 (transverse sides) and two long narrow sides 18, 19 (longitudinal sides).
- the carrier 2 in each case in the middle of a strip-shaped grip tab 20.
- the pull tab 20 is located in front of a groove-like recess 21, which is formed in the outside of the short narrow side 16,17.
- the groove-like recess 21 extends in the vertical direction in the skirt 11, through the baseboard 12 and the upper portion 13 of the skirt 11 therethrough.
- the grip tab 20 is connected at the bottom in the region of the groove-like recess 21 to the lower edge 22 of the skirt 11. From its connection 23, it extends a short distance horizontally away from the skirt 11. After that, it runs vertically upwards at a distance from the bottom of the recess 21. In this area, its outside is aligned with the outside of the baseboard 12. At the level of the top of the baseboard 12, the handle tab 20 has an angled portion and above the angled portion 24, the handle tab 20 extends vertically upward beyond the top wall 7.
- the upper end of the grip tab is arranged, for example, approximately at the level of the upper end of the pipette tips 3 inserted into the carrier 2.
- the grip tab 20 has a locking bead 25 projecting outwards in a horizontal direction. At the upper end, the grip tab on a horizontally outwardly projecting handle bar 26.
- each short narrow side 16 17 are on both sides next to the handle tab 20 vertically extending grooves 27, 28 are formed.
- the grooves 27, 28 are each bounded at its outer edge by the outer edge of the groove-shaped recess 21. At their inner edge they are each bounded by the grip tab 20.
- the grooves 27, 28 each have one in the direction of the short narrow side 16, 17 measured groove width of 2.5mm to 5mm. In the example, it is 4mm horizontally. Further, the grooves 27, 28 each horizontally and perpendicular to the short narrow side 16, 17 in the region of the skirting 12 measured groove depth of 1.5 to 2.5 mm. In the example, the groove depth is 2mm.
- the carrier 2 is made of plastic, preferably polypropylene (PP). Further preferably, the carrier 2 is produced by injection molding. Preferably, it is injection molded in one piece.
- PP polypropylene
- the pipette tips 3 are small plastic tubes which at the bottom have a lower through-opening 29 for liquid and at the top an upper through-opening 30 for air.
- the cross section of the pipette tips 3 increases from the lower to the upper through hole.
- a receiving volume 31 for liquid is present in the pipette tips 3.
- the pipette tips 3 have a peripherally projecting peripheral collar 32, with which they are supported on the edge of the holes 9.
- the lower part 4 has a substantially rectangular bottom wall 33 and upstanding first side walls 34, 35 and second side walls 36, 37 from the lateral edges of the bottom wall.
- the bottom wall 33 has feet 38 with a bottom surface 39 at the bottom.
- Each side wall 34 to 37 has a bulge 40 inwardly at a distance from its upper and two vertical edges, which extends to the bottom wall 33. In the area of the bulges 40, the lateral edges of the bottom wall 33 are slightly retracted. The bulges 40 stiff the lower part 4.
- the side walls 34 to 37 define a receptacle 41 with a rectangular upper opening 42 (see. Fig. 9, 10th ).
- the receptacle 41 is dimensioned such that the carrier 2 equipped with pipette tips 3 can be inserted from above through the upper opening 42 into the receptacle 41.
- the dimensions of the upper opening 42 exceed in both directions in each case by a few millimeters, the base surface of the carrier second
- the first side walls 34, 35 define the shorter edges of the upper opening 42 and the second side walls 36, 37 define the longer edges of the upper opening.
- the first side walls 34, 35 project upwardly from the bottom wall 33 upwardly than the second side walls 36, 37.
- first and second side walls 34 to 37 From the inner sides of the first and second side walls 34 to 37 are means for supporting the carrier in the form of vertical ribs 43 before (see. Fig. 5 and 16 ).
- first side walls 34 35 each have two ribs 43 are present.
- second side walls 36 37 each have four ribs 43 are present. These ribs 43 are based on the bottom of the upper edges of the bulges 40 from.
- first and second sidewalls 34 to 37 there is a respective diagonal rib 44 which is oriented at an angle of 45 ° to the two adjacent sidewalls 34 to 37.
- This diagonal rib 44 extends vertically down to the bottom wall 33.
- the ribs 43, 44 project so far from the inner sides of the side walls 34 to 37, that the carrier 2 with the lower edge of the skirt 11 on the ribs 43, 44 can be placed.
- each first side wall 34, 35 has at their inner, spaced from the first wall edges edges 45 with inwardly into the receptacle 41 in inclined bevels 46 on the outer sides (see. Fig. 5 ).
- the two middle ribs 43 on the inside of each second side wall 36, 37 at their remote from the second side wall 36, 37, inner edges protruding projections 45 with inwardly into the receptacle 41 in inclined bevels 46 at the outsides (cf. Fig. 16 ).
- the projections 45 with the chamfers 46 serve to engage behind the inside of the skirt 11 of the carrier 2 in the region of the skirting 12, in order to compensate for production-related indentations.
- each case two spaced-apart, vertical guide ribs 47 are present.
- the guide ribs 47 are supported at the bottom at the upper edge of the curvature 40 of the first side wall 34, 35 and extend vertically upwards above the ribs 43, 44.
- the guide ribs 47 project into the regions of the first side walls 34, 35. which protrude beyond the second side walls 36, 37. There they end at the height of the upper edge of the second side walls 36, 37.
- Each guide rib 47 has a rib width of 2.5 mm to 4 mm measured horizontally in the direction of the first side wall 34, 35. In the example, it is 3mm.
- each guide rib 47 has a rib height of 2.5mm to 4mm measured horizontally perpendicular to the first side wall 34, 35. In the example, it is 3mm.
- Each guide rib 47 is formed from a group of two parallel rib members 48, 49.
- Each rib member 48, 49 has a width of 0.5 to 1.5mm. In the example it is 1mm. Further, the distance between the rib members 48, 49 of a group is 0.5mm to 1.5mm. In the example it is 1mm. Due to these dimensions of the guide ribs 47 and their design of two rib elements 48, 49, a low-friction displacement of the carrier 2 for correct alignment of the grooves 27, 28 is given to the guide ribs 47.
- each first side wall 34, 35 has outside of the ribs 43 projecting from the inside and vertically extending guide webs 51.
- the guide webs 51 are based on the bottom of the upper edge of the curvature 40 of the first side walls 34, 35 and end up below the upper edge of the first side walls 34, 35 in an insertion bevel 52.
- the guide webs 51 project less far than the ribs 43 and guide ribs 47 from the inner sides of the first side wall 34, 35. In the example, it is 0.5 mm.
- the ribs 43 protrude inward on the inner sides of the first and second side walls 34 to 37 2mm to 4mm. In the example, it is 3mm.
- the diagonal ribs 44 project 4mm to 8mm inwards. In the example it is 6mm.
- the lower part is made of plastic, preferably of PP. Further preferably, the lower part is produced by injection molding. It is preferably injection molded in one piece.
- the carrier 2 equipped with pipette tips 3 can be inserted through the upper opening 42 of the lower part 4 into the receptacle 41.
- the guide webs 51 facilitate the exact alignment of the carrier 2 between the first side walls 34, 35. If in this case the carrier is not exactly aligned with the receptacle, the support 2 is supported by the lower edges 22 of the baseboard 12 and the handle tabs 20 on the upper ends of the guide ribs 47 from (see. Fig. 9, 10th ).
- the carrier 2 is displaceable in a horizontal direction parallel to the first side walls 34, 35 until the guide ribs 47 are aligned exactly with the grooves 27, 28 on the short narrow sides 16, 17 of the carrier 2.
- the support 2 can be unlocked by pivoting the grip tabs 20 together and can be pulled out of the lower part 4 on the grip tabs 20. Thereafter, a stocked with fresh pipette tips 3 carrier 2 in the lower part 4 in the manner described can be used.
- This section 13 may contain product information that is easy for the user can be detected. These are, for example, information about the filling volume and the type of pipette tips.
- Fig. 14 to 16 covers a protective cover 5, the pipette tips 3 and is supported with its lower edge on top of the baseboard 12 from.
- the protective cover 5 has opening regions 53, 54, through which the grip flaps 20 can be actuated.
- the equipped with pipette tips 3 and covered by the protective cover carrier 2 is inserted into the lower part 4.
- the pipette tips 3 are protected by the protective cover 5.
- the first side walls 34, 35 have slightly below their upper edge at a short distance from the first side wall two outwardly horizontally projecting pins 55, 56 (see. Fig. 11 to 16 ).
- a hood-like cover 6 is mounted on bearing eyes 57, 58 in strip-shaped bearing portions 59, 60.
- the lid 6 has at the lower edge of its opposite longitudinal side on a locking tab 61.
- the locking tab 61 has a third locking bead 62 on its inner side, which cooperates with a at the upper edge of the second side wall 36 outwardly projecting fourth latching bead 63.
- the cover 6 covers the carrier 2 with the inserted pipette tips 3 and is locked to the lower part 4.
- the cover 6 In the open position, the cover 6 is folded outwards by more than 90 ° and is supported by the lower edge of its longitudinal side next to the bearing sections 59, 60 on the outside of the second side wall 37. In this position, the carrier 2 can be inserted and removed and are pipette tips 3 of the inserted carrier 2 detachable.
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- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Packaging Of Annular Or Rod-Shaped Articles, Wearing Apparel, Cassettes, Or The Like (AREA)
- Packages (AREA)
Claims (16)
- Dispositif pour fournir des embouts de pipette, avec• un support (2) en forme de plaque avec une surface de base essentiellement rectangulaire,• une multiplicité de trous (9) dans le support (2), orientés perpendiculairement à la surface de base,• au moins un évidement (21) placé verticalement dans les côtés extérieurs de deux petits côtés (16, 17) du support (2) réciproquement opposés qui sont dimensionnés pour loger respectivement deux nervures de guidage (47) verticales, espacées l'une de l'autre, avec une largeur de nervure de respectivement 2,5 mm à 4 mm au moins partiellement et avec une hauteur de nervure de respectivement 2,5 mm à 4 mm au moins partiellement,• des embouts de pipette (3) introduits dans les trous (9),• une partie inférieure (4) avec des parois latérales (34 à 37), dressées à partir d'une surface d'appui (39), qui entourent un logement (41) rectangulaire pour le support (2) avec les embouts de pipette (3) introduites, deux premières parois latérales (34, 35) réciproquement opposées faisant saillie à partir de la surface d'appui (39) plus loin vers le haut que deux deuxièmes parois latérales (35, 36) réciproquement opposées,• des moyens d'appui (43, 44) sur les côtés intérieurs d'au moins deux parois latérales réciproquement opposées, qui sont constitués de telle sorte qu'ils supportent le support (2) dans une orientation horizontale sur les bords inférieurs (22) de petits côtés (16, 17) au-dessous des bords supérieurs de toutes les parois latérales (34 à 37), et• deux nervures de guidage (47) verticales espacées l'une de l'autre avec une largeur de nervure de respectivement 2,5 mm à 4 mm et une hauteur de nervure de respectivement 2,5 mm à 4 mm sur le côté intérieur de chaque première paroi latérale (34, 35), les deux nervures de guidage (47) engrenant dans l'évidement (21) au moins au nombre de un dans un côté étroit (16, 17) du support (2) quand le support (2) est posé sur les moyens d'appui (43, 44).
- Dispositif selon la revendication 1, dans lequel chaque nervure de guidage (47) est formée d'un groupe avec au moins deux éléments de nervure (48, 49) parallèles, chaque élément de nervure ayant une largeur de 0,50 à 1,5 mm, et la distance entre les éléments de nervure (48, 49) d'un groupe étant comprise entre 0,5 mm et 1,5 mm.
- Dispositif selon la revendication 1 ou 2, dans lequel les dimensions du support (2) dans une direction parallèle aux deux parois latérales (36, 37) sur le bord inférieur du support (2) sont inférieures de 4 mm à 7 mm à la distance entre les des premières parois latérales (34, 35) sur le bord supérieur des premières parois latérales (34, 35).
- Dispositif selon l'une des revendications 1 à 3, dans lequel les évidements (21) dans au moins un petit côté du support sont deux rainures (27, 28) verticales espacées l'une de l'autre, avec une largeur de rainure de respectivement 2,5 mm à 4,5 mm.
- Dispositif selon l'une des revendications 1 à 4, dans lequel l'évidement (21) au moins au nombre de un est limité, dans au moins un petit côté (16, 17) du support (2), sur son bord extérieur, par une plinthe (12) placée sur le long du bord inférieur du support (2) et faisant saillie vers l'extérieur.
- Dispositif selon l'une des revendications 1 à 5, dans lequel l'évidement (21) au moins au nombre de un est, dans au moins un petit côté (16, 17), sur son côté intérieur, limité par une languette de préhension (20) qui est liée en bas au bord inférieur du petit côté (16, 17) du support (2) et s'étend à distance du petit côté (16, 17) vers le haut jusqu'au-delà des premières parois latérales (34, 35).
- Dispositif selon la revendication 6, dans lequel au moins une languette de préhension (20) présente, sur son côté extérieur, au-dessus de sa liaison (23) avec le support (2), un premier moyen d'encliquetage (25) qui est encliqueté avec un deuxième moyen d'encliquetage (50) sur le côté intérieur de la première paroi latérale (34, 35) voisine.
- Dispositif selon l'une des revendications 1 à 7, dans lequel le support (2) présente une paroi de couverture (7) horizontale avec des trous (9) qui y sont ménagés, et un tablier (11) périphérique faisant saillie vers le bas à partir des bords latéraux de la paroi de couverture (7).
- Dispositif selon la revendication 8, dans lequel le tablier (11) présente, à l'extérieur de l'évidement (21), un tronçon inférieur faisant saillie vers l'extérieur et formant la plinthe (12).
- Dispositif selon la revendication 8 ou 9, dans lequel les bords des trous (9) sont raccordés à des douilles (10) dépassant du côté intérieur de la paroi de couverture (7) dans lesquelles les embouts de pipette (3) sont introduits.
- Dispositif selon l'une des revendications 7 à 10, dans lequel les languettes de préhension (20) sont en forme de bande et ont des premiers moyens d'encliquetage (25) ayant la forme d'au moins un bourrelet d'encliquetage (25) horizontal faisant saillie vers l'extérieur.
- Dispositif selon l'une des revendications 1 à 11, dans lequel les moyens d'appui (43, 44) comprennent des nervures verticales faisant saillie à partir des côtés intérieurs des parois latérales.
- Dispositif selon l'une des revendications 1 à 12, dans lequel les moyens d'appui (43, 44) présentent au moins partiellement sur leurs bords intérieurs des saillies (45) dressées, avec des chanfreins (46) inclinés vers l'intérieur dans le logement (41) sur les côtés extérieurs, qui agrippent intérieurement par l'arrière le tablier (11) du support (2).
- Dispositif selon l'une des revendications 1 à 13, dans lequel un capot de protection (5) est placé sur le côté supérieur du support (2) et recouvre les embouts de pipette (3) introduits dans les trous (9).
- Dispositif selon l'une des revendications 1 à 14, dans lequel la partie inférieure (4) présente un couvercle (6) supporté en pivotement qui, dans la position de fermeture, recouvre le logement avec un support (2) introduit et éventuellement le capot de protection (5) qui est placé dessus, et qui peut pivoter vers une position d'ouverture dans laquelle le support (2) avec les embouts de pipette (3) et le capot de protection (5) éventuellement posé peut être enlevé de la partie inférieure (4) et être introduit dans cette partie inférieure (4) et dans lequel des embouts de pipette (3) peuvent être enlevés du support (2).
- Dispositif selon l'une des revendications 1 à 15, dans lequel le support (2) et/ou la partie inférieure (4) et/ou le capot de protection (5) et/ou le couvercle (6) sont réalisés en au moins une matière plastique.
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13001900.3A EP2789389B1 (fr) | 2013-04-12 | 2013-04-12 | Dispositif pour stockage et pour fournir des embouts de pipette |
US14/250,530 US9433944B2 (en) | 2013-04-12 | 2014-04-11 | Device for Providing pipette tips |
CN201410333840.XA CN104150101B (zh) | 2013-04-12 | 2014-04-14 | 用于提供吸管头的装置 |
TW103113505A TW201501798A (zh) | 2013-04-12 | 2014-04-14 | 用於提供吸量管尖的裝置 |
KR1020140043973A KR102272579B1 (ko) | 2013-04-12 | 2014-04-14 | 피펫 팁을 제공하기 위한 장치 |
HK14112826.9A HK1199234A1 (en) | 2013-04-12 | 2014-12-23 | Device for providing pipette tips |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13001900.3A EP2789389B1 (fr) | 2013-04-12 | 2013-04-12 | Dispositif pour stockage et pour fournir des embouts de pipette |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2789389A1 EP2789389A1 (fr) | 2014-10-15 |
EP2789389B1 true EP2789389B1 (fr) | 2015-07-29 |
Family
ID=48183978
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP13001900.3A Active EP2789389B1 (fr) | 2013-04-12 | 2013-04-12 | Dispositif pour stockage et pour fournir des embouts de pipette |
Country Status (6)
Country | Link |
---|---|
US (1) | US9433944B2 (fr) |
EP (1) | EP2789389B1 (fr) |
KR (1) | KR102272579B1 (fr) |
CN (1) | CN104150101B (fr) |
HK (1) | HK1199234A1 (fr) |
TW (1) | TW201501798A (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10654042B2 (en) | 2016-11-14 | 2020-05-19 | Eppendorf Ag | Device for providing pipette tips |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3628404B1 (fr) | 2010-03-18 | 2021-06-30 | Biotix, Inc. | Plateaux d'embout de pipette |
WO2014130679A1 (fr) | 2013-02-21 | 2014-08-28 | Biotix, Inc. | Support pour pointes de pipette |
EP3006110A1 (fr) | 2014-10-10 | 2016-04-13 | F.Hoffmann-La Roche Ag | Grille |
CN104888878B (zh) * | 2015-06-16 | 2016-08-24 | 大连大学 | 模块拼装式移液器枪头盒 |
AT517655B1 (de) * | 2015-08-21 | 2019-08-15 | Greiner Bio One Gmbh | Pipettenspitzen-Aufnahmebehälter sowie Verfahren zu dessen Bereitstellung |
KR101749600B1 (ko) * | 2015-09-04 | 2017-06-22 | 서울대학교 산학협력단 | 샘플 농축 장치 및 이를 이용하여 농축된 샘플 추출 방법 |
US11173492B2 (en) * | 2017-02-03 | 2021-11-16 | Biotix, Inc. | Efficiently nested pipette tip arrays and related methods |
USD886321S1 (en) * | 2018-01-19 | 2020-06-02 | Biotix, Inc. | Pipette tip rack assembly |
USD888280S1 (en) * | 2018-03-29 | 2020-06-23 | Biotix, Inc. | Pipette tip tray |
JP6694486B2 (ja) * | 2018-03-29 | 2020-05-13 | バイオティクス, インコーポレイテッド | 剛性を高められたピペットチップトレイ |
USD918416S1 (en) * | 2018-06-01 | 2021-05-04 | Biolog-id | Set of drawer trays for medical and laboratory equipment |
USD908241S1 (en) * | 2018-06-01 | 2021-01-19 | Biolog-id | Drawer for medical and laboratory equipment |
USD914239S1 (en) * | 2018-08-29 | 2021-03-23 | Sartorius Biohit Liquid Handling Oy | Pipette tip rack |
USD923816S1 (en) | 2019-03-20 | 2021-06-29 | Biotix, Inc. | Pipette tip tray |
US11642677B2 (en) * | 2019-12-05 | 2023-05-09 | QIS, Inc. | Split microplate and vials |
JP2024505026A (ja) | 2021-01-26 | 2024-02-02 | ベクトン ディキンソン フランス | タブ内の複数のネストの確実な整列を保証するクリップ付きプランジャーストッパの包装用のネスト |
EP4218852A1 (fr) * | 2022-01-28 | 2023-08-02 | Becton Dickinson France | Dispositif et système de transport de dispositifs médicaux |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
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DE9310258U1 (de) * | 1993-07-09 | 1993-08-26 | Carl Roth GmbH & Co, 76185 Karlsruhe | Verpackungseinheit für Pipettenspitzen |
JP3214380B2 (ja) * | 1997-01-07 | 2001-10-02 | 住友電装株式会社 | メールコネクタ、分岐接続箱 |
DE19742493C1 (de) * | 1997-09-26 | 1999-02-18 | Eppendorf Geraetebau Netheler | Magazin für Pipettenspitzen |
US6062388A (en) * | 1998-06-24 | 2000-05-16 | Ohayon; Abraham | Stackable bins |
FR2784076B1 (fr) * | 1998-10-06 | 2000-12-22 | Gilson Sa | Ensemble comprenant des recharges de cones de pipette empilees |
US6019225A (en) * | 1998-10-26 | 2000-02-01 | Matrix Technologies Corp. | Pipette tip rack with array of interconnected sleeves |
PL351910A1 (en) * | 2002-01-29 | 2003-08-11 | Pz Htl Sa | Container for holding pipette tips |
DE102005035335B4 (de) * | 2005-07-28 | 2012-10-31 | Eppendorf Ag | Gefäßhalter |
WO2008107961A1 (fr) * | 2007-03-05 | 2008-09-12 | Daikyo Seiko, Ltd. | Réceptacle médical |
CA2724132C (fr) * | 2009-12-10 | 2018-03-06 | F. Hoffmann-La Roche Ag | Systeme d'amplification avec separation spatiale |
EP3628404B1 (fr) * | 2010-03-18 | 2021-06-30 | Biotix, Inc. | Plateaux d'embout de pipette |
DE102011106598A1 (de) * | 2011-06-16 | 2012-12-20 | Eppendorf Ag | Vorrichtung zum Bereitstellen von Pipettenspitzen |
US9150333B2 (en) * | 2011-06-16 | 2015-10-06 | Eppendorf Ag | Device for providing pipette tips |
-
2013
- 2013-04-12 EP EP13001900.3A patent/EP2789389B1/fr active Active
-
2014
- 2014-04-11 US US14/250,530 patent/US9433944B2/en active Active
- 2014-04-14 KR KR1020140043973A patent/KR102272579B1/ko active IP Right Grant
- 2014-04-14 CN CN201410333840.XA patent/CN104150101B/zh active Active
- 2014-04-14 TW TW103113505A patent/TW201501798A/zh unknown
- 2014-12-23 HK HK14112826.9A patent/HK1199234A1/xx unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10654042B2 (en) | 2016-11-14 | 2020-05-19 | Eppendorf Ag | Device for providing pipette tips |
Also Published As
Publication number | Publication date |
---|---|
US9433944B2 (en) | 2016-09-06 |
US20140308181A1 (en) | 2014-10-16 |
KR20140123454A (ko) | 2014-10-22 |
CN104150101A (zh) | 2014-11-19 |
CN104150101B (zh) | 2018-02-13 |
KR102272579B1 (ko) | 2021-07-05 |
HK1199234A1 (en) | 2015-06-26 |
TW201501798A (zh) | 2015-01-16 |
EP2789389A1 (fr) | 2014-10-15 |
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