EP2419399A4 - Compositions and methods for the treatment of inflammation - Google Patents
Compositions and methods for the treatment of inflammationInfo
- Publication number
- EP2419399A4 EP2419399A4 EP20100764985 EP10764985A EP2419399A4 EP 2419399 A4 EP2419399 A4 EP 2419399A4 EP 20100764985 EP20100764985 EP 20100764985 EP 10764985 A EP10764985 A EP 10764985A EP 2419399 A4 EP2419399 A4 EP 2419399A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- inflammation
- compositions
- treatment
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16873909P | 2009-04-13 | 2009-04-13 | |
| US17480609P | 2009-05-01 | 2009-05-01 | |
| PCT/US2010/030813 WO2010120719A1 (en) | 2009-04-13 | 2010-04-13 | Compositions and methods for the treatment of inflammation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EP2419399A1 EP2419399A1 (en) | 2012-02-22 |
| EP2419399A4 true EP2419399A4 (en) | 2012-08-29 |
| EP2419399B1 EP2419399B1 (en) | 2016-03-23 |
Family
ID=42982804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP10764985.7A Not-in-force EP2419399B1 (en) | 2009-04-13 | 2010-04-13 | Compositions and methods for the treatment of inflammation |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8673881B2 (en) |
| EP (1) | EP2419399B1 (en) |
| JP (1) | JP5785537B2 (en) |
| CN (1) | CN104203901A (en) |
| AU (1) | AU2010236663B2 (en) |
| BR (1) | BRPI1011325A2 (en) |
| CA (1) | CA2758586A1 (en) |
| CL (1) | CL2011002548A1 (en) |
| ES (1) | ES2576086T3 (en) |
| HK (1) | HK1166305A1 (en) |
| IL (1) | IL215592A (en) |
| MX (1) | MX2011010827A (en) |
| NZ (1) | NZ596228A (en) |
| RU (1) | RU2543720C2 (en) |
| TW (1) | TW201039815A (en) |
| WO (1) | WO2010120719A1 (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7582785B2 (en) * | 2002-04-01 | 2009-09-01 | University Of Southern California | Trihydroxy polyunsaturated eicosanoid derivatives |
| US8900626B2 (en) * | 2011-06-20 | 2014-12-02 | Senju Usa, Inc. | Transdermal drug delivery system and method of using the same |
| RU2497498C2 (en) * | 2012-02-14 | 2013-11-10 | Константин Николаевич Руссков | Pharmaceutical composition mytomycin-o for preventing proliferative cell-mediated response |
| EP2887932B1 (en) | 2012-08-22 | 2020-05-20 | Rosenberg Messina, David Rafael | Use of statins for periodontal disease and bone regeneration |
| US20150246061A1 (en) * | 2012-10-19 | 2015-09-03 | Celus Pharmaceuticals, Inc. | Vitamin d analogues for the treatment of a neurological disorder |
| CN105163732B (en) | 2013-02-22 | 2020-01-07 | 南加州大学 | Methods for treating ophthalmic diseases and disorders |
| WO2016028800A1 (en) * | 2014-08-20 | 2016-02-25 | A.T. Resolve Sarl | Treatment of corneal haze |
| WO2016144569A1 (en) | 2015-03-10 | 2016-09-15 | Elc Management Llc | Methods and compositions for treating skin to resolve inflammation and screening for actives that stimulate pro-resolution pathways |
| CN105287480B (en) * | 2015-10-28 | 2019-01-11 | 西安医学院第一附属医院 | Application of the Resolvin D1 as antiepileptic |
| EP3624815A4 (en) * | 2017-05-15 | 2021-01-20 | Stem Cell Medicine Ltd. | Treatment of multiple sclerosis with long acting glatiramer and adipose-derived stem cells |
| CN107445821A (en) * | 2017-08-11 | 2017-12-08 | 上海中医药大学 | Carbene acid derivative |
| KR20210061357A (en) | 2018-09-04 | 2021-05-27 | 미네르바 뉴로사이언스즈, 인크. | How to use phenoxypropylamine compounds to treat pain |
| US20220347223A1 (en) * | 2019-08-27 | 2022-11-03 | Cellin Technologies Oü | Activated mesenchymal stem cells for treating limb ischemia |
| EP4072578A4 (en) * | 2019-12-09 | 2024-01-10 | Univ Louisiana State | Biomolecule for treatment of corneal pathologies |
| CN110988180A (en) * | 2019-12-19 | 2020-04-10 | 山东达因海洋生物制药股份有限公司 | Method for analyzing related substances of esomeprazole magnesium based on hybrid mass spectrometry |
| WO2023250031A1 (en) * | 2022-06-21 | 2023-12-28 | Anida Pharma Inc. | Compositions and methods for treating hearing and ocular disorders |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050228047A1 (en) * | 2002-04-01 | 2005-10-13 | Petasis Nicos A | Trihydroxy polyunsaturated eicosanoid derivatives |
| WO2009038671A2 (en) * | 2007-09-14 | 2009-03-26 | Resolvyx Pharmaceuticals, Inc. | Oxylipin compounds for treating autoimmune diseases |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4172896A (en) | 1978-06-05 | 1979-10-30 | Dainippon Pharmaceutical Co., Ltd. | Methane-sulfonamide derivatives, the preparation thereof and composition comprising the same |
| US4444784A (en) | 1980-08-05 | 1984-04-24 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
| DK149080C (en) | 1980-06-06 | 1986-07-28 | Sankyo Co | METHOD FOR PREPARING ML-236B CARBOXYLIC ACID DERIVATIVES |
| US5354772A (en) | 1982-11-22 | 1994-10-11 | Sandoz Pharm. Corp. | Indole analogs of mevalonolactone and derivatives thereof |
| US4681893A (en) | 1986-05-30 | 1987-07-21 | Warner-Lambert Company | Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis |
| JP2648897B2 (en) | 1991-07-01 | 1997-09-03 | 塩野義製薬株式会社 | Pyrimidine derivatives |
| GB9217295D0 (en) | 1992-08-14 | 1992-09-30 | Wellcome Found | Controlled released tablets |
| US5541231A (en) | 1993-07-30 | 1996-07-30 | Glaxo Wellcome Inc. | Stabilized Pharmaceutical |
| US5358970A (en) | 1993-08-12 | 1994-10-25 | Burroughs Wellcome Co. | Pharmaceutical composition containing bupropion hydrochloride and a stabilizer |
| GB9315856D0 (en) | 1993-07-30 | 1993-09-15 | Wellcome Found | Stabilized pharmaceutical |
| CA2296080C (en) | 1997-07-29 | 2005-02-01 | Alcon Laboratories, Inc. | Ophthalmic compositions containing galactomannan polymers and borate |
| US6110973A (en) | 1998-01-29 | 2000-08-29 | Sepracor | Methods for treating obesity and weight gain using optically pure (-)-bupropion |
| US8889112B2 (en) | 1999-09-16 | 2014-11-18 | Ocularis Pharma, Llc | Ophthalmic formulations including selective alpha 1 antagonists |
| US6831186B2 (en) * | 2001-11-06 | 2004-12-14 | Schering Aktiengesellschft | Lipoxin A4 analogs |
| EP1453819A2 (en) | 2001-12-03 | 2004-09-08 | Novozymes A/S | Statin-like compounds |
| US6933289B2 (en) | 2003-07-01 | 2005-08-23 | Allergan, Inc. | Inhibition of irritating side effects associated with use of a topical ophthalmic medication |
| WO2005014046A2 (en) | 2003-08-07 | 2005-02-17 | Allergan, Inc. | Compositions for delivery of therapeutics into the eyes and methods for making and using the same |
| US20050059744A1 (en) | 2003-09-12 | 2005-03-17 | Allergan, Inc. | Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions |
| JP5421272B2 (en) * | 2007-10-12 | 2014-02-19 | リゾルヴィクス・ファーマシューティカルズ・インコーポレイテッド | Compositions and methods for the treatment of eye diseases |
| DE102008027146B4 (en) | 2008-06-02 | 2012-01-19 | Ing. Erich Pfeiffer Gmbh | discharge |
| US8619544B2 (en) | 2008-09-23 | 2013-12-31 | Qualcomm Incorporated | Apparatus and method for facilitating transmit diversity for communications |
| WO2010039531A1 (en) | 2008-09-23 | 2010-04-08 | Resolvyx Pharmaceuticals, Inc. | Therapeutic compounds |
-
2010
- 2010-03-30 TW TW099109567A patent/TW201039815A/en unknown
- 2010-04-13 BR BRPI1011325A patent/BRPI1011325A2/en not_active IP Right Cessation
- 2010-04-13 ES ES10764985.7T patent/ES2576086T3/en active Active
- 2010-04-13 US US13/264,155 patent/US8673881B2/en not_active Expired - Fee Related
- 2010-04-13 MX MX2011010827A patent/MX2011010827A/en active IP Right Grant
- 2010-04-13 WO PCT/US2010/030813 patent/WO2010120719A1/en active Application Filing
- 2010-04-13 EP EP10764985.7A patent/EP2419399B1/en not_active Not-in-force
- 2010-04-13 CA CA2758586A patent/CA2758586A1/en not_active Abandoned
- 2010-04-13 JP JP2012506110A patent/JP5785537B2/en not_active Expired - Fee Related
- 2010-04-13 NZ NZ596228A patent/NZ596228A/en not_active IP Right Cessation
- 2010-04-13 RU RU2011146005/04A patent/RU2543720C2/en not_active IP Right Cessation
- 2010-04-13 CN CN201080026180.0A patent/CN104203901A/en active Pending
- 2010-04-13 AU AU2010236663A patent/AU2010236663B2/en not_active Ceased
-
2011
- 2011-10-06 IL IL215592A patent/IL215592A/en not_active IP Right Cessation
- 2011-10-13 CL CL2011002548A patent/CL2011002548A1/en unknown
-
2012
- 2012-07-12 HK HK12106889.7A patent/HK1166305A1/en not_active IP Right Cessation
-
2014
- 2014-03-12 US US14/207,342 patent/US9315447B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050228047A1 (en) * | 2002-04-01 | 2005-10-13 | Petasis Nicos A | Trihydroxy polyunsaturated eicosanoid derivatives |
| WO2009038671A2 (en) * | 2007-09-14 | 2009-03-26 | Resolvyx Pharmaceuticals, Inc. | Oxylipin compounds for treating autoimmune diseases |
Non-Patent Citations (2)
| Title |
|---|
| "Organikum", 1990, DEUTSCHER VERLAG DER WISSENSCHAFTEN, Berlin, ISBN: 3-326-00076-6, article H.G.O. BECKER ET AL., pages: 414 - 415, XP002679881 * |
| See also references of WO2010120719A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104203901A (en) | 2014-12-10 |
| BRPI1011325A2 (en) | 2016-03-15 |
| JP5785537B2 (en) | 2015-09-30 |
| RU2543720C2 (en) | 2015-03-10 |
| US8673881B2 (en) | 2014-03-18 |
| CL2011002548A1 (en) | 2012-07-20 |
| HK1166305A1 (en) | 2012-10-26 |
| US9315447B2 (en) | 2016-04-19 |
| WO2010120719A1 (en) | 2010-10-21 |
| TW201039815A (en) | 2010-11-16 |
| IL215592A0 (en) | 2011-12-29 |
| RU2011146005A (en) | 2013-05-20 |
| EP2419399B1 (en) | 2016-03-23 |
| AU2010236663B2 (en) | 2015-08-20 |
| US20120101061A1 (en) | 2012-04-26 |
| NZ596228A (en) | 2014-01-31 |
| US20140275247A1 (en) | 2014-09-18 |
| CA2758586A1 (en) | 2010-10-21 |
| MX2011010827A (en) | 2012-01-20 |
| EP2419399A1 (en) | 2012-02-22 |
| ES2576086T3 (en) | 2016-07-05 |
| IL215592A (en) | 2017-02-28 |
| JP2012523459A (en) | 2012-10-04 |
| AU2010236663A1 (en) | 2011-11-24 |
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Ipc: A61P 27/02 20060101ALI20120716BHEP Ipc: C07C 69/734 20060101ALI20120716BHEP Ipc: A61K 31/201 20060101ALI20120716BHEP Ipc: C07C 69/732 20060101AFI20120716BHEP |
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