EP2381852A2 - Ancrage apical des muscles papillaires en vue d'une réduction du ventricule gauche - Google Patents
Ancrage apical des muscles papillaires en vue d'une réduction du ventricule gaucheInfo
- Publication number
- EP2381852A2 EP2381852A2 EP10738954A EP10738954A EP2381852A2 EP 2381852 A2 EP2381852 A2 EP 2381852A2 EP 10738954 A EP10738954 A EP 10738954A EP 10738954 A EP10738954 A EP 10738954A EP 2381852 A2 EP2381852 A2 EP 2381852A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- tether
- papillary muscle
- patient
- heart
- left ventricle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0487—Suture clamps, clips or locks, e.g. for replacing suture knots; Instruments for applying or removing suture clamps, clips or locks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/064—Surgical staples, i.e. penetrating the tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/064—Surgical staples, i.e. penetrating the tissue
- A61B17/0644—Surgical staples, i.e. penetrating the tissue penetrating the tissue, deformable to closed position
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/122—Clamps or clips, e.g. for the umbilical cord
- A61B17/1227—Spring clips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00238—Type of minimally invasive operation
- A61B2017/00243—Type of minimally invasive operation cardiac
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0409—Instruments for applying suture anchors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B2017/0496—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials for tensioning sutures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2454—Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses
- A61F2/2457—Chordae tendineae prostheses
Definitions
- This invention relates to devices and methods for the therapeutic changing of the geometry of the left ventricle of the human heart. Specifically, the invention relates to the apical introduction of an anchoring device to align the papillary muscles.
- Heart disease in the U.S. each year. That is about 29% of all U.S. deaths. Heart disease is a term that includes several more specific heart conditions.
- Cardiomyopathy is a weakening of the heart muscle or a change in heart muscle structure. It often results in inadequate heart pumping or other heart function abnormalities. These can result from various causes, including prior heart attacks, viral or bacterial infections, and others.
- the geometry of the myocardium is critical to proper functioning.
- the myocardium is comprised of a single, continuous tissue that wraps around itself, spiraling up from the apex of the heart, to form a helix with elliptically shaped ventricles. This spiral produces an oblique muscle fiber orientation, meaning that the fibers form a more ventricle 'x' shape, so that when fibers shorten 15%, it produces a 60% ejection fraction. Because of its elliptical shape and defined apex, the ventricle is subjected to a relatively low level of lateral stress.
- a dilated left ventricle is generally due to the effects of a myocardial infarction.
- An occlusion, or blockage, of cardiac arteries results in either an akinetic (non- beating) or dyskinetic (irregular beating) tissue downstream from the occlusion.
- This downstream ventricular tissue is damaged, but since the volume of blood that fills the ventricle does not change, the damaged organ has to work harder to eject the blood.
- This increased load causes an increase in the radius of the ventricle and the thickness of the ventricular wall changes.
- the apex of the heart becomes circular, the remaining myocardial tissue suffers from pathological hypertrophy, and the valve opening widens.
- the muscle fiber orientation which is critical to a good ejection fraction, becomes transverse, or more horizontal. Subsequently, the ejection fraction decreases; a 15% shortening of muscle fibers now produces only a 30% ejection fraction. The lateral stress on the ventricle increases. Overall, the dilated left ventricle cannot produce a strong enough pulse to maintain health and efficient circulatory return.
- Ventricular reduction is a well-known type of operation in cardiac surgery to reduce enlargement of the heart from cardiomyopathy.
- Vincent Dor, MD introduced endoventricular circular patch plasty (EVCPP), or the Dor procedure, as a viable method for restoring a dilated left ventricle to its normal, elliptical geometry.
- the Dor procedure which uses a circular suture and a Dacron® patch to correct LV aneurysms and exclude scarred parts of the septum and ventricular wall, has been one option for ventricular remodeling.
- a method for improving cardiac function comprising the steps of: inserting a tether device into a patient; and inserting said tether device through the apex of the patient's heart and into the left ventricle of the patient's heart; and attaching at least one first papillary muscle anchor of said tether device to a first papillary muscle within said left ventricle; and attaching at least one second papillary muscle anchor of said tether device to a second papillary muscle within the left ventricle wall of the patient's heart; and wherein said papillary anchor and said wall anchor are joined by a tether member so as to change the geometry and reduce the volume of the left ventricle.
- a method for reducing ventricular volume comprising the steps of : inserting a tether device into a patient; and inserting said tether device through the apex of the patient's heart and into the left ventricle of the patient's heart; and attaching at least one first papillary muscle anchor of said tether device to a first papillary muscle within said left ventricle; and attaching at least one second papillary muscle anchor of said tether device to a second papillary muscle of the left ventricle of the patient's heart; and wherein said papillary anchor and said wall anchor are joined by a tether member so as to reduce the volume of the left ventricle, [para 19] In another preferred embodiment of the invention, there is provided a method as described herein further comprising the step of adjusting the tether member to achieve a desired geometry of the left ventricle.
- a method as described herein further comprising where inserting the tether device into a patient is performed by inserting a catheter into the patient through the vascular system of the patient, [para 24] In another preferred embodiment of the invention, there is provided a method as described herein further comprising implanting a hemostasis valve at the apex insertion site on the heart of the patient, wherein said valve is a blood leakage control valve/sleeve, [para 25] In another preferred embodiment of the invention, there is provided a medical device for improving cardiac function or reducing ventricular volume, comprising: a cannula having a tethering device disposed therein; said cannula having a trocar for piercing the apex of the patient's heart and a leakage control hemostasis valve/sleeve; said tethering device comprising at least one first papillary muscle anchor for attaching to a first papillary muscle within said left ventricle and
- a device as described herein further comprising at least one additional papillary anchor joined by an additional tether member so as to achieve a desired geometry of the left ventricle,
- the tether member is comprised of nitinol (nickel-titanium shape memory alloy) or austinetic stainless steel.
- FIGURE IA is a graphical representation of an apical introduction device used to align papillary muscles.
- FIGURE IA shows cannula and the tethering member with four protruding anchors and depth gauge.
- FIGURE IB is a graphical representation of an apical introduction device used to align papillary muscles.
- FIGURE IB shows cannula and the tethering member with three protruding anchors and depth gauge.
- FIGURE 1C is a graphical representation of an apical introduction device used to align papillary muscles.
- FIGURE 1C shows cannula and the tethering member with one protruding anchor and depth gauge.
- FIGURE 2 is a drawing of a heart having an enlarged left ventricle.
- FIGURE 3 is a drawing of a heart being apically pierced by a cathether.
- FIGURE 4 is a drawing of a heart having a first tether implanted in a papillary muscle.
- FIGURE 5 is a drawing of a heart having a second tether implanted in an opposing papillary muscle.
- FIGURE 6 is a drawing of a heart showing two papillary muscles tethered.
- FIGURE 7 is a drawing of a heart showing the tethers being cinched.
- FIGURE 8 is a drawing of corrected heart showing the tethers gathered by an adjustable connector.
- FIGURE 9 is a drawing of a heart showing a circular tether embodiment.
- FIGURE 10 is a photo representation of a heart in cross-section being pierced by a device and shows inserting at the apex.
- FIGURE 11 is a photo representation of a heart in cross-section being pierced through the papillary muscle.
- FIGURE 12 is a photo representation of a heart in cross-section being pierced by a device at the apex, and shows interaction with a papillary muscle.
- FIGURE 13 is a photo representation of a heart in longitudinal cross-section.
- FIGURE 14 is a photo representation of a heart in cross-section showing attachment of tether lines (in blue), prior to being cinched, or joined.
- anchors for the purposes of this application, is defined to mean any fastener.
- anchors may comprise C-shaped or semicircular hooks, curved hooks of other shapes, straight hooks, barbed hooks, clips of any kind, T-tags, or any other suitable fastener(s).
- anchors may comprise two tips that curve in opposite directions upon deployment, forming two intersecting semi-circles, circles, ovals, helices or the like.
- anchors are self-deforming. By “self-deforming” it is meant that anchors change from a first undeployed shape to a second deployed shape upon release of anchors from restraint in housing.
- Such self-deforming anchors may change shape as they are released from housing and enter papillary or myocardial tissue, to secure themselves to the tissue.
- a crimping device or other similar mechanism is not required on distal end to apply force to anchors to attach them to tissue.
- Self-deforming anchors may be made of any suitable material, such as a super- elastic or shape-memory material like Nitinol or spring stainless steel.
- anchors may be made of a non-shape-memory material and made be loaded into housing in such a way that they change shape upon release.
- anchors that are not self- deforming may be used, and such anchors may be secured to tissue via crimping, firing or the like. Even self-securing anchors may be crimped in some embodiments, to provide enhanced attachment to tissue.
- anchors may comprise one or more bioactive agent.
- anchors may comprise electrodes.
- Such electrodes may sense various parameters, such as but not limited to impedance, temperature and electrical signals. In other embodiments, such electrodes may be used to supply energy to tissue at ablation or sub-ablation amounts. Delivery of anchors may be accomplished by any suitable device and technique, such as by simply releasing the anchors. Any number, size and shape of anchors may be included in housing.
- Apical or apex refers to a known part of the heart, roughly equivalent to the peak at the bottom of the organ.
- Canula or cannula refers to a well-known tube-like medical instrument. It can be fitted with a trocar, a sharp pointed device for piercing tissue.
- Tether may be one long piece of material or two or more pieces and may comprise any suitable material, such as Nitinol, austinetic steel, suture, suture-like material, a Dacron strip or the like.
- Hemostasis valve refers to a device which allows the heart tissue to be pierced at the apex region with little or no blood loss. Similar valves/sleeves are well known in the venipuncture field where individual vacutainers can be repeatedly mounted on a single needle, and valves such as the Touehy Borst valve which allows multiple insertions of catheters while maintaining hemostasis.
- delivery of the tether device may be advanced by any suitable advancing or device placement method so long as it arrives at the apex of the heart.
- Many catheter-based, minimally invasive devices and methods for performing intravascular procedures are well known, and any such devices and methods, as well as any other devices or method later developed, may be used to advance or position delivery device into a desired location.
- a steerable guide catheter is first advanced percutaneously to the apex region. The steerable catheter is inserted into the left ventricle of the heart through the apex of the heart and thus into the space formed by left ventricle. An obturator pushes or holds the tissue in place once it has been pierced.
- the steerable catheter is easily advanced to the papillary muscle or to the ventricular wall, the anchor may then be advanced and inserted into the papillary muscle and/ or the LV myocardium.
- the anchor may then be advanced and inserted into the papillary muscle and/ or the LV myocardium.
- this is but one exemplary method and any other suitable method, combination of devices, etc. may be used.
- FIGURE IA is a graphical representation of an apical introduction device used to align papillary muscles.
- FIGURE IA shows cannula and the tethering member with four protruding anchors and depth gauge.
- FIGURE IB is a graphical representation of an apical introduction device used to align papillary muscles.
- FIGURE IB shows cannula and the tethering member with three protruding anchors and depth gauge.
- FIGURE 1C is a graphical representation of an apical introduction device used to align papillary muscles.
- FIGURE 1C shows cannula and the tethering member with two protruding anchors.
- FIGUREs 2 - 8 show a heart having an enlarged left ventricle 110, and the instant apical approach 112 to the left ventricle HO is depicted in HGURJt S 3-8.
- FIGURE 3 shows the loft ventricle is accessed by inserting a catheter 11-4 having a cannula 116 and trocar 118 that is advanced from into the left ventricle 110. Once the catheter 114 reaches the interior of the left ventricle, the trocar 118 is removed in favor of a sieerable guide catheter 120 winch permit introduction of tbe instruments which will be used to engage and tether the papillary muscles, as described in more detail below.
- the papillary muscles 210, 220 are grasped by partial or full penetration or piercing. This may be accomplished with a variety of grasping mechanisms, preferably including one or more piercing prongs extending from an instrument or catheter tool so as to grasp a target structure.
- grasping mechanisms preferably including one or more piercing prongs extending from an instrument or catheter tool so as to grasp a target structure.
- stecrable catheter 120 is fed through the guide catheter 11-4 to secure a first anchor 124 of a tether structure 122 (sec inset Fig. 3A) to one of the papillary muscles 210 in the left ventricle.
- the steerabSe catheter 120 is advanced from fhe distal end of the guide catheter 1 14 and may be observed in real time via any conventional imaging technique.
- a suture or clip applying instrument (tethering device) 122 is passed through the catheter 120.
- the instrument has a steerable tip so thai it may be directed to a position in opposed facing relation to a target portion of a papillary muscle.
- Disposed at or adjacent the distal end of the tethering instrument 122 in this embodiment is a clamp or clip 124 for secure attachment to the respective papillary muscle.
- the clip or clamp is advanced out of the deployment catheter and into engagement with respective papillary muscle. Any suitable mechanism can be sued to close the clip. If deemed necessary or desirable, one or more additional clips with tethers may be applied.
- non-absorbablc suture loopis may be applied directly in the papillary muscles.
- a variation of the Pcrclose ⁇ - ! ⁇ "> vasculature closure device which is a stitch knot transmitting device W'ith a suture cutter could be used apply a suture loop.
- laparoscopic devices such as the Quik-Stiteh Endoscopic Suturing System, that may be adapted to transvascularly securing a tether to the papillary muscles.
- the guide catheter 120 remains in place with the flexible tether strand(s) 126 extending therethrough from the respective secured clip/anchor 12'-1 on fiat papillary muscle 210. Then, steer able eathcter 120 attaches second anchor 128 to second papillary muscle 220.
- two tethers may have a knot transmitted to define the junction, or they arc clipped to one another through the existing guiding catheter, [para 67]
- the tethering and drawing of the papillary muscles towards one another may be conducted while monitoring the position of the muscles fluor ⁇ scopiealiy, and under intracardiac ultrasound guidance, so that the papillary muscles can be drawn to a desired transventrieular distance.
- Intra cardiac Echo Dopplcr can also be used to assess the severity of LV enlargement ' CV disease, or regurgitation, to adjust the length of the fathers to an optimum iransveniricular distance to suppress cardiac deficiency or regurgitation.
- FIGURES 8 and 9 show corrected left ventricle 1 10 having papular/ 210 held by anchor 124, and papillary 220 held by anchor 128, and joined by connector 134, which may ⁇ be adjustable. Any suitable instalment may be used to capture and sever the excess tether length such as, for example, a suture trimmer,
- FIGURE 10 is a photo representation of a heart in cross-section being pierced by a device and shows inserting at the apex.
- FIGURE 11 is a photo representation of a heart in cross-section being pierced through the ventricular wall.
- FIGURE 12 is a photo representation of a heart in cross-section being pierced by a device at the apex, and shows interaction with a papillary muscle.
- FIGURE 13 is a photo representation of a heart in cross-section.
- FIGURE 14 is a photo representation of a heart in cross-section showing attachment of tether lines (in blue), prior to being cinched, or joined.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Rheumatology (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US14614409P | 2009-01-21 | 2009-01-21 | |
PCT/US2010/021686 WO2010090878A2 (fr) | 2009-01-21 | 2010-01-21 | Ancrage apical des muscles papillaires en vue d'une réduction du ventricule gauche |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2381852A2 true EP2381852A2 (fr) | 2011-11-02 |
EP2381852A4 EP2381852A4 (fr) | 2014-06-11 |
Family
ID=42337564
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10738954.6A Withdrawn EP2381852A4 (fr) | 2009-01-21 | 2010-01-21 | Ancrage apical des muscles papillaires en vue d'une réduction du ventricule gauche |
Country Status (4)
Country | Link |
---|---|
US (1) | US20100185278A1 (fr) |
EP (1) | EP2381852A4 (fr) |
CA (1) | CA2768797A1 (fr) |
WO (1) | WO2010090878A2 (fr) |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102007043830A1 (de) | 2007-09-13 | 2009-04-02 | Lozonschi, Lucian, Madison | Herzklappenstent |
JP2013512765A (ja) | 2009-12-08 | 2013-04-18 | アヴァロン メディカル リミテッド | 経カテーテル僧帽弁置換術のためのデバイスおよびシステム |
US9307980B2 (en) | 2010-01-22 | 2016-04-12 | 4Tech Inc. | Tricuspid valve repair using tension |
US8475525B2 (en) * | 2010-01-22 | 2013-07-02 | 4Tech Inc. | Tricuspid valve repair using tension |
US8961596B2 (en) | 2010-01-22 | 2015-02-24 | 4Tech Inc. | Method and apparatus for tricuspid valve repair using tension |
US10058323B2 (en) | 2010-01-22 | 2018-08-28 | 4 Tech Inc. | Tricuspid valve repair using tension |
EP4032503A1 (fr) | 2010-07-09 | 2022-07-27 | Highlife SAS | Prothèse de valvule auriculo-ventriculaire transcathéter |
WO2013011502A2 (fr) | 2011-07-21 | 2013-01-24 | 4Tech Inc. | Procédé et appareil pour la réparation d'une valvule tricuspide en utilisant une tension |
US9480559B2 (en) | 2011-08-11 | 2016-11-01 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US9827092B2 (en) | 2011-12-16 | 2017-11-28 | Tendyne Holdings, Inc. | Tethers for prosthetic mitral valve |
CA2900930A1 (fr) | 2012-02-13 | 2013-08-22 | Mitraspan, Inc. | Procede et appareil de reparation d'une valvule mitrale |
US10076414B2 (en) | 2012-02-13 | 2018-09-18 | Mitraspan, Inc. | Method and apparatus for repairing a mitral valve |
US8961594B2 (en) | 2012-05-31 | 2015-02-24 | 4Tech Inc. | Heart valve repair system |
WO2014022124A1 (fr) | 2012-07-28 | 2014-02-06 | Tendyne Holdings, Inc. | Conceptions multi-composantes améliorées pour dispositif de récupération de valve cardiaque, structures d'étanchéité et ensemble stent |
WO2014021905A1 (fr) | 2012-07-30 | 2014-02-06 | Tendyne Holdings, Inc. | Systèmes et procédés d'administration améliorée pour valvules prothétiques transcathéter |
US9788948B2 (en) | 2013-01-09 | 2017-10-17 | 4 Tech Inc. | Soft tissue anchors and implantation techniques |
CN105208978B (zh) | 2013-03-14 | 2016-12-07 | 4科技有限公司 | 具有系绳接口的支架 |
US9486306B2 (en) | 2013-04-02 | 2016-11-08 | Tendyne Holdings, Inc. | Inflatable annular sealing device for prosthetic mitral valve |
US10463489B2 (en) | 2013-04-02 | 2019-11-05 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US11224510B2 (en) | 2013-04-02 | 2022-01-18 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US10478293B2 (en) | 2013-04-04 | 2019-11-19 | Tendyne Holdings, Inc. | Retrieval and repositioning system for prosthetic heart valve |
US9610159B2 (en) | 2013-05-30 | 2017-04-04 | Tendyne Holdings, Inc. | Structural members for prosthetic mitral valves |
EP3013281B1 (fr) | 2013-06-25 | 2018-08-15 | Tendyne Holdings, Inc. | Caractéristiques de gestion de thrombus et de conformité structurelle pour valvules cardiaques prothétiques |
AU2014286991A1 (en) * | 2013-07-11 | 2016-01-28 | Shifamed Holdings, Llc | Devices and methods for lung volume reduction |
AU2014296087B2 (en) | 2013-08-01 | 2019-08-01 | Tendyne Holdings, Inc. | Epicardial anchor devices and methods |
WO2015058039A1 (fr) | 2013-10-17 | 2015-04-23 | Robert Vidlund | Appareil et procedes d'alignement et de deploiement de dispositifs intracardiaques |
EP3656353A1 (fr) | 2013-10-28 | 2020-05-27 | Tendyne Holdings, Inc. | Valvule cardiaque prothétique et ses systèmes d'administration |
US9526611B2 (en) | 2013-10-29 | 2016-12-27 | Tendyne Holdings, Inc. | Apparatus and methods for delivery of transcatheter prosthetic valves |
US10052095B2 (en) | 2013-10-30 | 2018-08-21 | 4Tech Inc. | Multiple anchoring-point tension system |
EP3062709A2 (fr) | 2013-10-30 | 2016-09-07 | 4Tech Inc. | Système de tension à multiples points d'ancrage |
US10022114B2 (en) | 2013-10-30 | 2018-07-17 | 4Tech Inc. | Percutaneous tether locking |
WO2015120122A2 (fr) | 2014-02-05 | 2015-08-13 | Robert Vidlund | Appareil et procédés pour la mise en place d'une valve mitrale prothétique par l'artère fémorale |
US9986993B2 (en) | 2014-02-11 | 2018-06-05 | Tendyne Holdings, Inc. | Adjustable tether and epicardial pad system for prosthetic heart valve |
CA2937566C (fr) | 2014-03-10 | 2023-09-05 | Tendyne Holdings, Inc. | Dispositifs et procedes de positionnement et de controle de charge de cable d'attache pour valvule mitrale prothetique |
EP3157607B1 (fr) * | 2014-06-19 | 2019-08-07 | 4Tech Inc. | Serrage de tissu cardiaque |
EP3284412A1 (fr) | 2014-12-02 | 2018-02-21 | 4Tech Inc. | Ancrages tissulaires excentrés |
CA2972966C (fr) | 2015-01-07 | 2023-01-10 | Tendyne Holdings, Inc. | Protheses de valvules mitrales et appareil et procedes de mise en place associe |
CN107896484B (zh) | 2015-02-05 | 2020-09-08 | 坦迪尼控股股份有限公司 | 可膨胀的心外膜垫及其递送装置和方法 |
WO2016168609A1 (fr) | 2015-04-16 | 2016-10-20 | Tendyne Holdings, Inc. | Appareil et procédés de mise en place, de repositionnement et d'extraction de valvules prothétiques transcathéter |
US10327894B2 (en) | 2015-09-18 | 2019-06-25 | Tendyne Holdings, Inc. | Methods for delivery of prosthetic mitral valves |
AU2016362474B2 (en) | 2015-12-03 | 2021-04-22 | Tendyne Holdings, Inc. | Frame features for prosthetic mitral valves |
CN108366859B (zh) | 2015-12-28 | 2021-02-05 | 坦迪尼控股股份有限公司 | 用于假体心脏瓣膜的心房囊袋闭合件 |
US10470877B2 (en) | 2016-05-03 | 2019-11-12 | Tendyne Holdings, Inc. | Apparatus and methods for anterior valve leaflet management |
EP3468480B1 (fr) | 2016-06-13 | 2023-01-11 | Tendyne Holdings, Inc. | Administration séquentielle de valvule mitrale prothétique en deux parties |
CN109640887B (zh) | 2016-06-30 | 2021-03-16 | 坦迪尼控股股份有限公司 | 假体心脏瓣膜及用于输送其的装置和方法 |
EP3484411A1 (fr) | 2016-07-12 | 2019-05-22 | Tendyne Holdings, Inc. | Appareil et procédés de récupération transseptale de valvules cardiaques prothétiques |
CA3058150A1 (fr) | 2017-03-28 | 2018-10-04 | Cardiac Success Ltd. | Dispositifs de distribution d'une bande pour entourer plusieurs muscles papillaires dans le coeur |
US11318018B2 (en) | 2017-03-28 | 2022-05-03 | Cardiac Success Ltd. | Method of improving cardiac function |
US20180318082A1 (en) * | 2017-05-05 | 2018-11-08 | Edwards Lifesciences Corporation | Papillary muscle binding |
CA3068527C (fr) | 2017-07-13 | 2022-07-05 | Tendyne Holdings, Inc. | Valves cardiaques prothetiques et appareil et procedes associes de mise en place |
US11191639B2 (en) | 2017-08-28 | 2021-12-07 | Tendyne Holdings, Inc. | Prosthetic heart valves with tether coupling features |
WO2019079788A1 (fr) | 2017-10-20 | 2019-04-25 | Boston Scientific Scimed, Inc. | Implant de réparation de valvule cardiaque pour le traitement de la régurgitation tricuspide |
US11464638B2 (en) | 2017-10-23 | 2022-10-11 | Cardiac Success Ltd | Adjustable self-locking papillary muscle band |
BR112020008199A2 (pt) | 2017-10-23 | 2020-10-27 | Cardiac Success Ltd. | dispositivo para reposicionar músculos papilares |
US11413147B2 (en) | 2018-10-03 | 2022-08-16 | Edwards Lifesciences Corporation | Ventricular remodeling using coil devices |
US11413146B2 (en) | 2018-10-03 | 2022-08-16 | Edwards Lifesciences Corporation | Spring and coil devices for papillary muscle approximation and ventricle remodeling |
US11648110B2 (en) | 2019-12-05 | 2023-05-16 | Tendyne Holdings, Inc. | Braided anchor for mitral valve |
US11648114B2 (en) | 2019-12-20 | 2023-05-16 | Tendyne Holdings, Inc. | Distally loaded sheath and loading funnel |
US11951002B2 (en) | 2020-03-30 | 2024-04-09 | Tendyne Holdings, Inc. | Apparatus and methods for valve and tether fixation |
IT202000012562A1 (it) | 2020-05-27 | 2021-11-27 | Milano Politecnico | Dispositivo e assieme per riparare una valvola cardiaca |
US11857417B2 (en) | 2020-08-16 | 2024-01-02 | Trilio Medical Ltd. | Leaflet support |
WO2022039853A1 (fr) | 2020-08-19 | 2022-02-24 | Tendyne Holdings, Inc. | Tampon apical entièrement transseptal doté d'une poulie pour la mise sous tension |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003049619A2 (fr) * | 2001-12-08 | 2003-06-19 | Lattouf Omar M | Traitements pour un patient souffrant d'une insuffisance cardiaque congestive |
US20040186566A1 (en) * | 2003-03-18 | 2004-09-23 | Hindrichs Paul J. | Body tissue remodeling methods and apparatus |
WO2005102181A1 (fr) * | 2004-03-24 | 2005-11-03 | Aptus Endosystems, Inc. | Systemes et methodes de fixation d'une prothese dans une lumiere du corps ou un organe creux |
US20060030885A1 (en) * | 2002-10-15 | 2006-02-09 | Hyde Gregory M | Apparatuses and methods for heart valve repair |
US20060142784A1 (en) * | 2004-12-28 | 2006-06-29 | Stavros Kontos | Device and method for suturing internal structures puncture wounds |
US20070112425A1 (en) * | 2005-04-22 | 2007-05-17 | Laurent Schaller | Catheter-based tissue remodeling devices and methods |
US20070118151A1 (en) * | 2005-11-21 | 2007-05-24 | The Brigham And Women's Hospital, Inc. | Percutaneous cardiac valve repair with adjustable artificial chordae |
Family Cites Families (89)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1127325A (en) * | 1965-08-23 | 1968-09-18 | Henry Berry | Improved instrument for inserting artificial heart valves |
US3587115A (en) * | 1966-05-04 | 1971-06-28 | Donald P Shiley | Prosthetic sutureless heart valves and implant tools therefor |
US3548417A (en) * | 1967-09-05 | 1970-12-22 | Ronnie G Kischer | Heart valve having a flexible wall which rotates between open and closed positions |
US3671979A (en) * | 1969-09-23 | 1972-06-27 | Univ Utah | Catheter mounted artificial heart valve for implanting in close proximity to a defective natural heart valve |
US3657744A (en) * | 1970-05-08 | 1972-04-25 | Univ Minnesota | Method for fixing prosthetic implants in a living body |
US3714671A (en) * | 1970-11-30 | 1973-02-06 | Cutter Lab | Tissue-type heart valve with a graft support ring or stent |
US3755823A (en) * | 1971-04-23 | 1973-09-04 | Hancock Laboratories Inc | Flexible stent for heart valve |
US4035849A (en) * | 1975-11-17 | 1977-07-19 | William W. Angell | Heart valve stent and process for preparing a stented heart valve prosthesis |
CA1069652A (fr) * | 1976-01-09 | 1980-01-15 | Alain F. Carpentier | Valvule prosthetique avec anneau deformable |
US4056854A (en) * | 1976-09-28 | 1977-11-08 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Aortic heart valve catheter |
US4297749A (en) * | 1977-04-25 | 1981-11-03 | Albany International Corp. | Heart valve prosthesis |
US4265694A (en) * | 1978-12-14 | 1981-05-05 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Method of making unitized three leaflet heart valve |
US4222126A (en) * | 1978-12-14 | 1980-09-16 | The United States Of America As Represented By The Secretary Of The Department Of Health, Education & Welfare | Unitized three leaflet heart valve |
US4574803A (en) * | 1979-01-19 | 1986-03-11 | Karl Storz | Tissue cutter |
GB2056023B (en) * | 1979-08-06 | 1983-08-10 | Ross D N Bodnar E | Stent for a cardiac valve |
US4373216A (en) * | 1980-10-27 | 1983-02-15 | Hemex, Inc. | Heart valves having edge-guided occluders |
US4339831A (en) * | 1981-03-27 | 1982-07-20 | Medtronic, Inc. | Dynamic annulus heart valve and reconstruction ring |
US4470157A (en) * | 1981-04-27 | 1984-09-11 | Love Jack W | Tricuspid prosthetic tissue heart valve |
US4345340A (en) * | 1981-05-07 | 1982-08-24 | Vascor, Inc. | Stent for mitral/tricuspid heart valve |
US4406022A (en) * | 1981-11-16 | 1983-09-27 | Kathryn Roy | Prosthetic valve means for cardiovascular surgery |
SE445884B (sv) * | 1982-04-30 | 1986-07-28 | Medinvent Sa | Anordning for implantation av en rorformig protes |
GB8300636D0 (en) * | 1983-01-11 | 1983-02-09 | Black M M | Heart valve replacements |
US4535483A (en) * | 1983-01-17 | 1985-08-20 | Hemex, Inc. | Suture rings for heart valves |
US4612011A (en) * | 1983-07-22 | 1986-09-16 | Hans Kautzky | Central occluder semi-biological heart valve |
US4787899A (en) * | 1983-12-09 | 1988-11-29 | Lazarus Harrison M | Intraluminal graft device, system and method |
US4627436A (en) * | 1984-03-01 | 1986-12-09 | Innoventions Biomedical Inc. | Angioplasty catheter and method for use thereof |
US4592340A (en) * | 1984-05-02 | 1986-06-03 | Boyles Paul W | Artificial catheter means |
US4883458A (en) * | 1987-02-24 | 1989-11-28 | Surgical Systems & Instruments, Inc. | Atherectomy system and method of using the same |
US4979939A (en) * | 1984-05-14 | 1990-12-25 | Surgical Systems & Instruments, Inc. | Atherectomy system with a guide wire |
US5007896A (en) * | 1988-12-19 | 1991-04-16 | Surgical Systems & Instruments, Inc. | Rotary-catheter for atherectomy |
DE3442088A1 (de) * | 1984-11-17 | 1986-05-28 | Beiersdorf Ag, 2000 Hamburg | Herzklappenprothese |
US4759758A (en) * | 1984-12-07 | 1988-07-26 | Shlomo Gabbay | Prosthetic heart valve |
DE3530262A1 (de) * | 1985-08-22 | 1987-02-26 | Siemens Ag | Schaltungsanordnung zur pruefung eines passiven busnetzsystems (csma/cd-zugriffsverfahren) |
US4733665C2 (en) * | 1985-11-07 | 2002-01-29 | Expandable Grafts Partnership | Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft |
DE3640745A1 (de) * | 1985-11-30 | 1987-06-04 | Ernst Peter Prof Dr M Strecker | Katheter zum herstellen oder erweitern von verbindungen zu oder zwischen koerperhohlraeumen |
CH672247A5 (fr) * | 1986-03-06 | 1989-11-15 | Mo Vysshee Tekhnicheskoe Uchil | |
US4878906A (en) * | 1986-03-25 | 1989-11-07 | Servetus Partnership | Endoprosthesis for repairing a damaged vessel |
US4777951A (en) * | 1986-09-19 | 1988-10-18 | Mansfield Scientific, Inc. | Procedure and catheter instrument for treating patients for aortic stenosis |
US4878495A (en) * | 1987-05-15 | 1989-11-07 | Joseph Grayzel | Valvuloplasty device with satellite expansion means |
US4796629A (en) * | 1987-06-03 | 1989-01-10 | Joseph Grayzel | Stiffened dilation balloon catheter device |
US4829990A (en) * | 1987-06-25 | 1989-05-16 | Thueroff Joachim | Implantable hydraulic penile erector |
US4851001A (en) * | 1987-09-17 | 1989-07-25 | Taheri Syde A | Prosthetic valve for a blood vein and an associated method of implantation of the valve |
US5032128A (en) * | 1988-07-07 | 1991-07-16 | Medtronic, Inc. | Heart valve prosthesis |
DE8815082U1 (de) * | 1988-11-29 | 1989-05-18 | Biotronik Meß- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin, 1000 Berlin | Herzklappenprothese |
US4856516A (en) * | 1989-01-09 | 1989-08-15 | Cordis Corporation | Endovascular stent apparatus and method |
US4966604A (en) * | 1989-01-23 | 1990-10-30 | Interventional Technologies Inc. | Expandable atherectomy cutter with flexibly bowed blades |
US4994077A (en) * | 1989-04-21 | 1991-02-19 | Dobben Richard L | Artificial heart valve for implantation in a blood vessel |
US5047041A (en) * | 1989-08-22 | 1991-09-10 | Samuels Peter B | Surgical apparatus for the excision of vein valves in situ |
US4986830A (en) * | 1989-09-22 | 1991-01-22 | Schneider (U.S.A.) Inc. | Valvuloplasty catheter with balloon which remains stable during inflation |
US5089015A (en) * | 1989-11-28 | 1992-02-18 | Promedica International | Method for implanting unstented xenografts and allografts |
US5037434A (en) * | 1990-04-11 | 1991-08-06 | Carbomedics, Inc. | Bioprosthetic heart valve with elastic commissures |
US5085635A (en) * | 1990-05-18 | 1992-02-04 | Cragg Andrew H | Valved-tip angiographic catheter |
US5152771A (en) * | 1990-12-31 | 1992-10-06 | The Board Of Supervisors Of Louisiana State University | Valve cutter for arterial by-pass surgery |
US5282847A (en) * | 1991-02-28 | 1994-02-01 | Medtronic, Inc. | Prosthetic vascular grafts with a pleated structure |
JPH05184611A (ja) * | 1991-03-19 | 1993-07-27 | Kenji Kusuhara | 弁輪支持器具及びその取り付け方法 |
US5295958A (en) * | 1991-04-04 | 1994-03-22 | Shturman Cardiology Systems, Inc. | Method and apparatus for in vivo heart valve decalcification |
US5167628A (en) * | 1991-05-02 | 1992-12-01 | Boyles Paul W | Aortic balloon catheter assembly for indirect infusion of the coronary arteries |
US5397351A (en) * | 1991-05-13 | 1995-03-14 | Pavcnik; Dusan | Prosthetic valve for percutaneous insertion |
US5370685A (en) * | 1991-07-16 | 1994-12-06 | Stanford Surgical Technologies, Inc. | Endovascular aortic valve replacement |
US5584803A (en) * | 1991-07-16 | 1996-12-17 | Heartport, Inc. | System for cardiac procedures |
US5163953A (en) * | 1992-02-10 | 1992-11-17 | Vince Dennis J | Toroidal artificial heart valve stent |
US5332402A (en) * | 1992-05-12 | 1994-07-26 | Teitelbaum George P | Percutaneously-inserted cardiac valve |
US5797960A (en) * | 1993-02-22 | 1998-08-25 | Stevens; John H. | Method and apparatus for thoracoscopic intracardiac procedures |
US5728151A (en) * | 1993-02-22 | 1998-03-17 | Heartport, Inc. | Intercostal access devices for less-invasive cardiovascular surgery |
US6406420B1 (en) * | 1997-01-02 | 2002-06-18 | Myocor, Inc. | Methods and devices for improving cardiac function in hearts |
US6045497A (en) * | 1997-01-02 | 2000-04-04 | Myocor, Inc. | Heart wall tension reduction apparatus and method |
US6332893B1 (en) * | 1997-12-17 | 2001-12-25 | Myocor, Inc. | Valve to myocardium tension members device and method |
US7674222B2 (en) * | 1999-08-09 | 2010-03-09 | Cardiokinetix, Inc. | Cardiac device and methods of use thereof |
US6402781B1 (en) * | 2000-01-31 | 2002-06-11 | Mitralife | Percutaneous mitral annuloplasty and cardiac reinforcement |
US6537198B1 (en) * | 2000-03-21 | 2003-03-25 | Myocor, Inc. | Splint assembly for improving cardiac function in hearts, and method for implanting the splint assembly |
US6723038B1 (en) * | 2000-10-06 | 2004-04-20 | Myocor, Inc. | Methods and devices for improving mitral valve function |
US6810882B2 (en) * | 2001-01-30 | 2004-11-02 | Ev3 Santa Rosa, Inc. | Transluminal mitral annuloplasty |
US20020188170A1 (en) * | 2001-04-27 | 2002-12-12 | Santamore William P. | Prevention of myocardial infarction induced ventricular expansion and remodeling |
US20040064014A1 (en) * | 2001-05-31 | 2004-04-01 | Melvin David B. | Devices and methods for assisting natural heart function |
US6793673B2 (en) * | 2002-12-26 | 2004-09-21 | Cardiac Dimensions, Inc. | System and method to effect mitral valve annulus of a heart |
US6764510B2 (en) * | 2002-01-09 | 2004-07-20 | Myocor, Inc. | Devices and methods for heart valve treatment |
JP2005534361A (ja) * | 2002-06-27 | 2005-11-17 | リーバイン,ロバート,エイ. | 房室弁逆流及び心室リモデリング逆転のためのシステム及び方法 |
US7745532B2 (en) * | 2002-08-02 | 2010-06-29 | Cambridge Polymer Group, Inc. | Systems and methods for controlling and forming polymer gels |
US7335213B1 (en) * | 2002-11-15 | 2008-02-26 | Abbott Cardiovascular Systems Inc. | Apparatus and methods for heart valve repair |
US7404824B1 (en) * | 2002-11-15 | 2008-07-29 | Advanced Cardiovascular Systems, Inc. | Valve aptation assist device |
US7316706B2 (en) * | 2003-06-20 | 2008-01-08 | Medtronic Vascular, Inc. | Tensioning device, system, and method for treating mitral valve regurgitation |
US20060252868A1 (en) * | 2005-05-09 | 2006-11-09 | Ashland Inc. | Low-density, class a sheet molding compounds from isophthalate-maleate thermoset resins |
US20090082619A1 (en) * | 2005-06-09 | 2009-03-26 | De Marchena Eduardo | Method of treating cardiomyopathy |
EP1887981A2 (fr) * | 2005-06-09 | 2008-02-20 | The University Of Miami | Fixation aux muscles papillaires pour reduction ventriculaire gauche |
US20070078297A1 (en) * | 2005-08-31 | 2007-04-05 | Medtronic Vascular, Inc. | Device for Treating Mitral Valve Regurgitation |
US7632308B2 (en) * | 2005-11-23 | 2009-12-15 | Didier Loulmet | Methods, devices, and kits for treating mitral valve prolapse |
US8043368B2 (en) * | 2005-11-23 | 2011-10-25 | Traves Dean Crabtree | Methods and apparatus for atrioventricular valve repair |
US8388680B2 (en) * | 2006-10-18 | 2013-03-05 | Guided Delivery Systems, Inc. | Methods and devices for catheter advancement and delivery of substances therethrough |
EP3915490A1 (fr) * | 2007-10-19 | 2021-12-01 | Ancora Heart, Inc. | Systèmes de remodelage cardiaque |
-
2010
- 2010-01-21 WO PCT/US2010/021686 patent/WO2010090878A2/fr active Application Filing
- 2010-01-21 CA CA2768797A patent/CA2768797A1/fr not_active Abandoned
- 2010-01-21 EP EP10738954.6A patent/EP2381852A4/fr not_active Withdrawn
- 2010-01-21 US US12/691,591 patent/US20100185278A1/en not_active Abandoned
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003049619A2 (fr) * | 2001-12-08 | 2003-06-19 | Lattouf Omar M | Traitements pour un patient souffrant d'une insuffisance cardiaque congestive |
US20060030885A1 (en) * | 2002-10-15 | 2006-02-09 | Hyde Gregory M | Apparatuses and methods for heart valve repair |
US20040186566A1 (en) * | 2003-03-18 | 2004-09-23 | Hindrichs Paul J. | Body tissue remodeling methods and apparatus |
WO2005102181A1 (fr) * | 2004-03-24 | 2005-11-03 | Aptus Endosystems, Inc. | Systemes et methodes de fixation d'une prothese dans une lumiere du corps ou un organe creux |
US20060142784A1 (en) * | 2004-12-28 | 2006-06-29 | Stavros Kontos | Device and method for suturing internal structures puncture wounds |
US20070112425A1 (en) * | 2005-04-22 | 2007-05-17 | Laurent Schaller | Catheter-based tissue remodeling devices and methods |
US20070118151A1 (en) * | 2005-11-21 | 2007-05-24 | The Brigham And Women's Hospital, Inc. | Percutaneous cardiac valve repair with adjustable artificial chordae |
Non-Patent Citations (1)
Title |
---|
See also references of WO2010090878A2 * |
Also Published As
Publication number | Publication date |
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US20100185278A1 (en) | 2010-07-22 |
EP2381852A4 (fr) | 2014-06-11 |
CA2768797A1 (fr) | 2010-08-12 |
WO2010090878A2 (fr) | 2010-08-12 |
WO2010090878A3 (fr) | 2010-11-04 |
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