EP2368124A4 - Verfahren zur bestimmung der aktivität eines pegylierten blutgerinnungsfaktors in einem siliciumbasierten aktivierten teil-thromboplastin-zeitassay - Google Patents

Verfahren zur bestimmung der aktivität eines pegylierten blutgerinnungsfaktors in einem siliciumbasierten aktivierten teil-thromboplastin-zeitassay

Info

Publication number
EP2368124A4
EP2368124A4 EP09828376A EP09828376A EP2368124A4 EP 2368124 A4 EP2368124 A4 EP 2368124A4 EP 09828376 A EP09828376 A EP 09828376A EP 09828376 A EP09828376 A EP 09828376A EP 2368124 A4 EP2368124 A4 EP 2368124A4
Authority
EP
European Patent Office
Prior art keywords
silica
blood coagulation
coagulation factor
factor activity
partial thromboplastin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09828376A
Other languages
English (en)
French (fr)
Other versions
EP2368124A1 (de
Inventor
Liang Tang
Heiner Apeler
Philip Ramsey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Healthcare LLC
Original Assignee
Bayer Healthcare LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare LLC filed Critical Bayer Healthcare LLC
Publication of EP2368124A1 publication Critical patent/EP2368124A1/de
Publication of EP2368124A4 publication Critical patent/EP2368124A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP09828376A 2008-11-24 2009-11-24 Verfahren zur bestimmung der aktivität eines pegylierten blutgerinnungsfaktors in einem siliciumbasierten aktivierten teil-thromboplastin-zeitassay Withdrawn EP2368124A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11734508P 2008-11-24 2008-11-24
PCT/US2009/065732 WO2010060081A1 (en) 2008-11-24 2009-11-24 Method of determining pegylated blood coagulation factor activity in a silica-based activated partial thromboplastin time assay

Publications (2)

Publication Number Publication Date
EP2368124A1 EP2368124A1 (de) 2011-09-28
EP2368124A4 true EP2368124A4 (de) 2012-09-19

Family

ID=42198546

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09828376A Withdrawn EP2368124A4 (de) 2008-11-24 2009-11-24 Verfahren zur bestimmung der aktivität eines pegylierten blutgerinnungsfaktors in einem siliciumbasierten aktivierten teil-thromboplastin-zeitassay

Country Status (4)

Country Link
EP (1) EP2368124A4 (de)
JP (1) JP2012510060A (de)
CA (1) CA2744340A1 (de)
WO (1) WO2010060081A1 (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2772051C (en) 2009-08-24 2020-08-18 Amunix Operating Inc. Coagulation factor ix compositions and methods of making and using same
WO2013076157A1 (en) * 2011-11-22 2013-05-30 Universite Catholique De Louvain Marker for blood coagulation
SG11201403764XA (en) 2012-01-12 2014-07-30 Biogen Idec Inc Chimeric factor viii polypeptides and uses thereof
EP2814840B1 (de) 2012-02-15 2019-11-13 Bioverativ Therapeutics Inc. Faktor-viii-zusammensetzungen und verfahren zur herstellung und verwendung davon
EP3549953A1 (de) 2012-02-15 2019-10-09 Bioverativ Therapeutics Inc. Rekombinante faktor-viii-proteine
EP3674410A1 (de) 2012-07-11 2020-07-01 Bioverativ Therapeutics Inc. Faktor-viii-komplex mit xten und von-willebrand-faktor-protein sowie verwendungen davon
SG11201509313PA (en) * 2013-06-28 2016-01-28 Biogen Ma Inc Thrombin cleavable linker with xten and its uses thereof
EP3013359A4 (de) * 2013-06-28 2017-01-25 Biogen MA Inc. Thrombinspaltfähiger linker
US10548953B2 (en) 2013-08-14 2020-02-04 Bioverativ Therapeutics Inc. Factor VIII-XTEN fusions and uses thereof
KR102409250B1 (ko) 2014-01-10 2022-06-14 바이오버라티브 테라퓨틱스 인크. 인자 viii 키메라 단백질 및 이들의 용도
US10473612B2 (en) 2014-09-26 2019-11-12 Abbott Point Of Care Inc. Cartridge device identification for coagulation assays in fluid samples
US10247741B2 (en) 2014-09-26 2019-04-02 Abbott Point Of Care Inc. Microfabricated device with micro-environment sensors for assaying coagulation in fluid samples
WO2016049527A1 (en) 2014-09-26 2016-03-31 Abbott Point Of Care Inc. Cartridge device with segmented fluidics for assaying coagulation in fluid samples
EP3955003B1 (de) 2014-09-26 2023-06-21 Abbott Point Of Care Inc Sensoren zur prüfung auf koagulation in flüssigen proben
US10048282B2 (en) 2014-09-26 2018-08-14 Abbott Point Of Care Inc. Cartridge device with fluidic junctions for coagulation assays in fluid samples
CN107110875A (zh) 2014-09-26 2017-08-29 雅培医护站股份有限公司 用在凝固测定中的鞣花酸制剂
EP4043879A1 (de) 2014-09-26 2022-08-17 Abbott Point Of Care Inc Einzelkanalkartuschenvorrichtung für blutgerinnungstests in fluidproben
WO2017024060A1 (en) 2015-08-03 2017-02-09 Biogen Ma Inc. Factor ix fusion proteins and methods of making and using same
CN108344875B (zh) * 2017-01-22 2021-11-02 上海长岛生物技术有限公司 提高活化部分凝血活酶时间试剂对肝素敏感性的方法及用途
TW202015723A (zh) 2018-05-18 2020-05-01 美商百歐維拉提夫治療公司 治療ａ型血友病的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101226201A (zh) * 2008-02-05 2008-07-23 长安大学 活化部分凝血活酶时间(aptt)测定试剂

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG152262A1 (en) * 2004-04-22 2009-05-29 Regado Biosciences Inc Improved modulators of coagulation factors
WO2005114140A1 (en) * 2004-05-20 2005-12-01 Inverness Medical Switzerland Gmbh A device and method for detecting blood coagulation
HUE033776T2 (en) * 2004-11-12 2018-01-29 Bayer Healthcare Llc FVIII site-specific modification

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101226201A (zh) * 2008-02-05 2008-07-23 长安大学 活化部分凝血活酶时间(aptt)测定试剂

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 200904, Derwent World Patents Index; AN 2009-A80942 *
M.J. RAY ET AL: "A comparison of two APTT reagents which use silica activators", CLINICAL & LABORATORY HAEMATOLOGY, vol. 11, no. 3, 1 September 1989 (1989-09-01), pages 221 - 232, XP055034678, ISSN: 0141-9854, DOI: 10.1111/j.1365-2257.1989.tb00212.x *
See also references of WO2010060081A1 *

Also Published As

Publication number Publication date
WO2010060081A1 (en) 2010-05-27
JP2012510060A (ja) 2012-04-26
CA2744340A1 (en) 2010-05-27
EP2368124A1 (de) 2011-09-28

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