EP2314380B1 - Dispenser - Google Patents

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Publication number
EP2314380B1
EP2314380B1 EP10011452.9A EP10011452A EP2314380B1 EP 2314380 B1 EP2314380 B1 EP 2314380B1 EP 10011452 A EP10011452 A EP 10011452A EP 2314380 B1 EP2314380 B1 EP 2314380B1
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EP
European Patent Office
Prior art keywords
liquid storage
capillary channel
liquid
storage reservoir
discharging device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
EP10011452.9A
Other languages
German (de)
French (fr)
Other versions
EP2314380A2 (en
EP2314380A3 (en
Inventor
Jürgen Greiner-Perth
Matthias Wochele
Peter Stadelhofer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aptar Radolfzell GmbH
Original Assignee
Aptar Radolfzell GmbH
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Publication date
Application filed by Aptar Radolfzell GmbH filed Critical Aptar Radolfzell GmbH
Publication of EP2314380A2 publication Critical patent/EP2314380A2/en
Publication of EP2314380A3 publication Critical patent/EP2314380A3/en
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Publication of EP2314380B1 publication Critical patent/EP2314380B1/en
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0039—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means
    • B05B11/0044—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means
    • B05B11/00442—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means the means being actuated by the difference between the atmospheric pressure and the pressure inside the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0039—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means
    • B05B11/0044—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means
    • B05B11/00446—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means the means being located at the bottom of the container or of an enclosure surrounding the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/02—Membranes or pistons acting on the contents inside the container, e.g. follower pistons
    • B05B11/026—Membranes separating the content remaining in the container from the atmospheric air to compensate underpressure inside the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1001—Piston pumps
    • B05B11/1023—Piston pumps having an outlet valve opened by deformation or displacement of the piston relative to its actuating stem
    • B05B11/1026—Piston pumps having an outlet valve opened by deformation or displacement of the piston relative to its actuating stem the piston being deformable and its deformation allowing opening of the outlet
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1028—Pumps having a pumping chamber with a deformable wall
    • B05B11/1032—Pumps having a pumping chamber with a deformable wall actuated without substantial movement of the nozzle in the direction of the pressure stroke
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1028—Pumps having a pumping chamber with a deformable wall
    • B05B11/1035—Pumps having a pumping chamber with a deformable wall the pumping chamber being a bellow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042—Components or details
    • B05B11/1043—Sealing or attachment arrangements between pump and container
    • B05B11/1046—Sealing or attachment arrangements between pump and container the pump chamber being arranged substantially coaxially to the neck of the container
    • B05B11/1047—Sealing or attachment arrangements between pump and container the pump chamber being arranged substantially coaxially to the neck of the container the pump being preassembled as an independent unit before being mounted on the container

Definitions

  • the invention relates to a discharge device for liquids, in particular for pharmaceutical liquids, with a conveyor, with a connected to the input side of the conveyor liquid storage for storing the liquid and with an output side of the conveyor associated discharge opening.
  • the liquid reservoir is at least partially formed as a formflexibler fluid pouch and arranged in a volume-constant receiving space.
  • Discharge devices for liquids in particular pharmaceutical liquids, are widely known from the prior art. They serve, for example, as donors for nasal, oral or other pharmaceutical applications as well as dispensers for cosmetic products.
  • a user can convey by means of the conveyor liquid from the liquid storage to the discharge, from where the liquid is discharged, for example in the form of a spray.
  • a particularly common design of such dispensers provides that the liquid storage has a fixed internal volume.
  • air can flow into the liquid reservoir through a compensation channel, so that the ambient pressure again approaches that in the liquid reservoir ,
  • the liquid storage is dimensionally flexible and thus can change its internal volume in the course of the discharge of liquid. It requires therefore no Nachströmens of air in the liquid storage. It is also known to arrange this form-flexible liquid storage within a volume-constant receiving space, so that the form-flexible liquid storage from the outside is not visible to the user and also a mechanical violation of the liquid storage is not to be feared.
  • a pressure equalization channel is usually provided, through which the receiving space is connected to an environment, so that the increase of not occupied by the liquid storage volume of the receiving space in the course of emptying the liquid reservoir can be compensated by inflowing air to thereby in Reception room and in the liquid storage environment pressure to maintain.
  • Such a discharge device is for example made US 2006/037968 A1 known, wherein a pressure equalization channel is provided on an outer side of the liquid reservoir, which is associated with a valve opening for the purpose of pressure equalization.
  • the known from the prior art generic construction is disadvantageous, since the thin wall of the flexible liquid reservoir usually can not prevent liquid from escaping from the liquid storage in the receiving space and thus takes place a change of liquid in the liquid storage, in particular a change in concentration of the active substance contained in the liquid in pharmaceutical fluids. Since in the generic discharge devices described a largely free air exchange between the not occupied by the liquid storage volume of the receiving space and an ambient atmosphere, however, there is no saturation of the air in the receiving space, so that the diffusion process between the liquid storage and the receiving space through the thin wall of the liquid storage progresses and increases with continuous duration, the change or reduction of the liquid in the liquid storage.
  • a pressure equalizing device for a double container wherein a channel between an inner container and an outer container is provided, with a cross-sectional area whose root is from 10 to 500 microns, and with a length which is five thousand times to one-tenth times as large as the root of the Querschnitss simulation at least one channel.
  • the channel of an embodiment is partially formed by a spiral groove on an outer side of the Au h reckoners.
  • the object of the invention is to provide a design for a generic discharge device, by which this disadvantageous diffusion process is prevented or reduced.
  • the receiving space is connected to an ambient atmosphere for the purpose of pressure equalization by at least one capillary channel.
  • Such a capillary channel has a thin and elongate shape and opens with its one end in the receiving space and with its other end in the region of the ambient atmosphere.
  • a pressure equalization possibility between the receiving space on the one hand and the ambient atmosphere on the other hand, but due to the design of the compound as a capillary channel, it comes nonetheless saturates the air in the receiving space with liquid which prevents further outdiffusion of liquid from the liquid storage when the discharge device is not used for an extended period of time.
  • the capillary channel forms a stable gradient in terms of humidity.
  • a capillary channel in the context of this invention, only channel sections are considered, which have a cross-sectional area less than 1 mm 2 .
  • a quotient of the length of the capillary channel divided by its average cross-sectional area is greater than 300 mm -1 , in particular greater than 1000 mm -1 .
  • a quotient of at least 2500 mm -1 is considered to be particularly advantageous.
  • a capillary channel with an average cross-sectional area of 0.03 mm 2 according to the invention thus has to have a length of at least about 10 mm.
  • the cross-sectional area is particularly small, in particular less than 0.05 mm 2 , preferably less than 0.02 mm 2 and ideally less than 0.01 mm 2 , Furthermore, it has been found that the length of the capillary channel should preferably be at least 10 mm, in particular at least 30 mm or even at least 50 mm.
  • the capillary channel is at least partially formed by a groove-like depression in an outer side of the liquid reservoir. This groove-like depression is easy to manufacture.
  • the capillary channel can then be closed by applying the outside or the inside of a counter component circumferentially. It is particularly advantageous if the capillary channel formed in the by a groove-like depression Area is jointly circumferentially closed by the receiving housing on the one hand and the liquid storage on the other hand. This results in a cost-effective and simple construction.
  • the flexible material, which is to be used for the liquid storage is particularly well suited for a circumferential sealing of the capillary channel.
  • the outer side of the liquid reservoir is considered to be a surface that does not come into contact with the liquid stored in the liquid reservoir as intended.
  • the region in which the capillary channel is introduced into the outside of the liquid reservoir preferably has a relative to the intended deforming part of the liquid storage increased wall thickness.
  • the groove-like depression extends at least in sections tangentially or spirally on the outside of the liquid reservoir or on the inside of the receiving housing.
  • Such a design makes it easy to achieve capillary channels of more than 50 mm in length even with small discharge devices of, for example, less than 20 mm in diameter.
  • the wall of the receiving housing is thicker than the wall of the liquid reservoir, so that diffusion through this wall does not take place or does not take place to a relevant extent.
  • the receiving housing has, at least in sections, a wall which consists of a material with a low diffusion rate, in particular of metal, ceramic or glass.
  • a radially outwardly pointing web is provided on the liquid reservoir formed as a liquid bag, which between the receiving housing and a separate and containing the conveyor housing part is arranged as a seal.
  • This bridge then takes on a dual function as a seal. On the one hand, it seals off the region of the receiving space not occupied by the liquid reservoir from the ambient atmosphere. On the other hand, it forms a seal in the transition region between the liquid reservoir and the conveyor with respect to an ambient atmosphere.
  • the web is interrupted by the capillary channel or the pressure equalization channel and takes over the sealing function only in the areas beyond this interruption.
  • the discharge devices shown in the figures are each designed as portable, mobile discharge devices and each have a manually operable conveyor as matching features 10, whose input side 10a is connected to a liquid reservoir 20 and whose output side 10b is connected to a discharge opening 12.
  • the conveyor 10 is designed as a piston pump.
  • the conveyor 10 is designed as a bellows pump.
  • the liquid reservoir 20 is designed as a fluid bag that is dimensionally flexible, so that it can in terms of its internal volume of each still in the liquid storage 20 located amount of liquid to be discharged 30 adapt.
  • All discharge devices of the embodiment is also common that the bag-like liquid storage 20 is arranged in a receiving space 42 formed by a receiving housing 40 and is thus protected against mechanical influences from the outside.
  • Fig. 1a represents a non-inventive embodiment in a delivery state.
  • the liquid reservoir 20 has its maximum volume, wherein this volume is dimensioned so that the liquid reservoir 20 fills the receiving space 42 only about 50%.
  • the portion 42a of the receiving space 42 not occupied by the liquid store is filled with air in this delivery condition, which is approximately at ambient pressure (1 bar).
  • the liquid reservoir 20 is connected in this as well as in all other embodiments only with the conveyor 10, so that the liquid 30 can escape in the liquid reservoir 20 at least in liquid form only in the direction of the conveyor 10 from the liquid reservoir 20. Also, as well as in all the illustrated embodiments in the embodiment of Fig. 1a and 1b provided that no possibility for ambient air of an ambient atmosphere 1 is to penetrate into the liquid storage 20 itself.
  • This seal also causes in the embodiment of the Fig. 1a and 1b Also, that the air-filled part 42a of the receiving space 42 is gas-tight with respect to an environment 1 is completed, so that neither in the liquid reservoir 20 still in the not occupied by the liquid reservoir 20 part 42a of the receiving space 42 air can penetrate from the outside.
  • the inner volume of the liquid reservoir 20 decreases, while the surrounding part 42a of the receiving space 42 is inevitably increased. Since no air can flow, this gradually leads to a reduction in the pressure in the receiving space 42, this pressure reduction due to the fact that already in the delivery state of the Fig. 1a a considerable amount of air in the receiving space 42 was present, only small fails.
  • the pressure in the receiving space is about 0.5 bar. Since the conveyor 10 is designed so that it can work against such a negative pressure, the functionality of the discharge device is always given.
  • Fig. 1b shows an intermediate state in which about half of the liquid 30 has been removed and in the receiving space 42, a pressure of about 0.8 bar, that is, a negative pressure relative to the environment of about 0.2 bar exists.
  • a capillary channel 60 is provided, which extends in a portion 60 a from the ambient atmosphere 1 to the collar 22 of the liquid reservoir 20.
  • a groove is formed, which forms an outwardly facing portion 60 b, a tangential portion 60 c and an inwardly radially pointing portion 60 d of the capillary channel 60. This groove is closed at its open side by the collar 44 of the receiving housing 40.
  • Air can pass through the capillary channel into the part 42a of the receiving space 42, so that pressure can equalize as the liquid reservoir 20 progresses.
  • the ambient pressure of about 1bar again.
  • the path of the air through the capillary channel 60 is in Fig. 1b illustrated by the dotted arrow 2.
  • connection in this design of Fig. 2a, 2b and 3 a connection between the ambient atmosphere 1 and the receiving space 42 given.
  • this connection does not cause the liquid diffused from the liquid store 20 to escape into the environment 1 into the part 42a of the receiving space 42 not occupied by the liquid store 20. Instead, a stable gradient in the capillary channel 60 is established between the saturated air in the part 42a and the air in the ambient atmosphere 1, which allows the liquid 30 diffused out of the liquid reservoir 20 to escape from the receiving space 42 only to a negligible extent.
  • the embodiment of the 4 and 5 shows a significantly different from the basic structure compared to the previous embodiments dispenser, but has a similar basic principle with respect to the ventilation of not occupied by the liquid reservoir 20 portion 42a of the receiving space 42.
  • a capillary channel 62 is provided, the first portion 62 a between two housing sections 14, 40 extends. This is followed by a section 62b of the capillary channel, which is formed as a helical groove on the outside of the liquid reservoir 20 and whose open side is closed by the inside of the Au touchgephases 40.
  • this capillary channel 62 is consistent with the operation of the capillary channel 60 of the embodiment of Fig. 2a, 2b and 3 match.
  • the air from the environment 1 can penetrate along the dotted arrow 4 in the receiving space 42.
  • the peculiarity lies here in particular in the large length of the capillary channel 62 by the spiral-shaped design.

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  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Coating Apparatus (AREA)

Description

Die Erfindung betrifft eine Austragvorrichtung für Flüssigkeiten, insbesondere für pharmazeutische Flüssigkeiten, mit einer Fördereinrichtung, mit einem mit der Eingangsseite der Fördereinrichtung verbundenen Flüssigkeitsspeicher zur Speicherung der Flüssigkeit sowie mit einer mit einer Ausgangsseite der Fördereinrichtung verbundenen Austragöffnung. Dabei ist der Flüssigkeitsspeicher zumindest abschnittsweise als formflexibler Flüssigkeitsbeutel ausgebildet und in einem volumenkonstanten Aufnahmeraum angeordnet.The invention relates to a discharge device for liquids, in particular for pharmaceutical liquids, with a conveyor, with a connected to the input side of the conveyor liquid storage for storing the liquid and with an output side of the conveyor associated discharge opening. In this case, the liquid reservoir is at least partially formed as a formflexibler fluid pouch and arranged in a volume-constant receiving space.

Aus dem Stand der Technik sind Austragvorrichtungen für Flüssigkeiten, insbesondere pharmazeutische Flüssigkeiten weithin bekannt. Sie dienen beispielsweise als Spender für nasale, orale oder anderweitige pharmazeutische Anwendungen sowie als Spender für Kosmetikprodukte. Ein Benutzer kann mittels der Fördereinrichtung Flüssigkeit aus dem Flüssigkeitsspeicher zur Austragöffnung fördern, von wo die Flüssigkeit beispielsweise in Form eines Sprühstrahls abgegeben wird.Discharge devices for liquids, in particular pharmaceutical liquids, are widely known from the prior art. They serve, for example, as donors for nasal, oral or other pharmaceutical applications as well as dispensers for cosmetic products. A user can convey by means of the conveyor liquid from the liquid storage to the discharge, from where the liquid is discharged, for example in the form of a spray.

Eine besonders übliche Gestaltung solcher Spender sieht vor, dass der Flüssigkeitsspeicher ein unveränderliches Innenvolumen aufweist. Um zu verhindern, dass sich in diesem Flüssigkeitsspeicher aufgrund des unveränderlichen Volumens im Zuge der Entnahme ein Unterdruck bildet, ist bei solchen Austragvorrichtungen zumeist vorgesehen, dass durch einen Ausgleichskanal Luft in den Flüssigkeitsspeicher nachströmen kann, so dass sich im Flüssigkeitsspeicher wieder in etwa der Umgebungsdruck einstellt.A particularly common design of such dispensers provides that the liquid storage has a fixed internal volume. In order to prevent a negative pressure forming in this liquid reservoir due to the fixed volume in the course of removal, it is usually provided in such discharge devices that air can flow into the liquid reservoir through a compensation channel, so that the ambient pressure again approaches that in the liquid reservoir ,

Bei gattungsgemäßen Austragvorrichtungen ist dagegen vorgesehen, dass der Flüssigkeitsspeicher formflexibel ist und somit im Zuge des Austrags von Flüssigkeit seine Innenvolumen verändern kann. Es bedarf daher keines Nachströmens von Luft in den Flüssigkeitsspeicher. Dabei ist es ebenfalls bekannt, diesen formflexiblen Flüssigkeitsspeicher innerhalb eines volumenkonstanten Aufnahmeraums anzuordnen, so dass der formflexible Flüssigkeitsspeicher von außen für den Benutzer nicht zu erkennen ist und auch eine mechanische Verletzung des Flüssigkeitsspeichers nicht zu befürchten ist. Auch bei solchen gattungsgemäßen Austragvorrichtungen wird üblicherweise jedoch ein Druckausgleichskanal vorgesehen, durch den der Aufnahmeraum mit einer Umgebung verbunden ist, so dass die Vergrößerung des nicht vom Flüssigkeitsspeicher eingenommenen Volumens des Aufnahmeraums im Zuge der Entleerung des Flüssigkeitsspeichers durch nachströmende Luft ausgeglichen werden kann, um hierdurch im Aufnahmeraum und im Flüssigkeitsspeicher Umgebungsdruck aufrechtzuerhalten.In generic dispensing devices, however, it is provided that the liquid storage is dimensionally flexible and thus can change its internal volume in the course of the discharge of liquid. It requires therefore no Nachströmens of air in the liquid storage. It is also known to arrange this form-flexible liquid storage within a volume-constant receiving space, so that the form-flexible liquid storage from the outside is not visible to the user and also a mechanical violation of the liquid storage is not to be feared. Even with such generic discharge devices, however, a pressure equalization channel is usually provided, through which the receiving space is connected to an environment, so that the increase of not occupied by the liquid storage volume of the receiving space in the course of emptying the liquid reservoir can be compensated by inflowing air to thereby in Reception room and in the liquid storage environment pressure to maintain.

Eine derartige Austragvorrichtung ist beispielsweise aus US 2006/037968 A1 bekannt, wobei ein Druckausgleichskanal an einer Außenseite des Flüssigkeitsspeichers vorgesehen ist, welchem ein zum Zwecke des Druckausgleichs öffnendes Ventil zugeordnet ist.Such a discharge device is for example made US 2006/037968 A1 known, wherein a pressure equalization channel is provided on an outer side of the liquid reservoir, which is associated with a valve opening for the purpose of pressure equalization.

Derartige Austragvorrichtung sind auch aus EP 1 295 646 A1 und EP 0 696 479 A1 bekannt.Such discharge are also off EP 1 295 646 A1 and EP 0 696 479 A1 known.

Es wurde jedoch festgestellt, dass die aus dem Stand der Technik bekannte gattungsgemäße Bauweise nachteilig ist, da die dünne Wandung des formflexiblen Flüssigkeitsspeichers üblicherweise nicht verhindern kann, dass Flüssigkeit aus dem Flüssigkeitsspeicher in den Aufnahmeraum entweicht und somit eine Veränderung der Flüssigkeit im Flüssigkeitsspeicher stattfindet, insbesondere eine Konzentrationsänderung des in der Flüssigkeit enthaltenen Wirkstoffes bei pharmazeutischen Flüssigkeiten. Da bei den beschriebenen gattungsgemäßen Austragvorrichtungen ein weitgehend freier Luftaustausch zwischen dem nicht vom Flüssigkeitsspeicher eingenommenen Volumen des Aufnahmeraums und einer Umgebungsatmosphäre besteht, kommt es allerdings nicht zu einer Sättigung der Luft im Aufnahmeraum, so dass der Diffusionsprozess zwischen dem Flüssigkeitsspeicher und dem Aufnahmeraum durch die dünne Wandung des Flüssigkeitsspeichers fortschreitet und mit fortwährender Dauer die Veränderung bzw. Verminderung der Flüssigkeit im Flüssigkeitsspeicher zunimmt.However, it has been found that the known from the prior art generic construction is disadvantageous, since the thin wall of the flexible liquid reservoir usually can not prevent liquid from escaping from the liquid storage in the receiving space and thus takes place a change of liquid in the liquid storage, in particular a change in concentration of the active substance contained in the liquid in pharmaceutical fluids. Since in the generic discharge devices described a largely free air exchange between the not occupied by the liquid storage volume of the receiving space and an ambient atmosphere, however, there is no saturation of the air in the receiving space, so that the diffusion process between the liquid storage and the receiving space through the thin wall of the liquid storage progresses and increases with continuous duration, the change or reduction of the liquid in the liquid storage.

Aus DE 198 51 404 A1 ist eine Druckausgleichsvorrichtung für einen Doppelbehälter bekannt, wobei ein Kanal zwischen einem Innenbehälter und einem Außenbehälter vorgesehen ist, mit einer Querschnittsfläche, deren Wurzel von 10 bis 500µm beträgt, und mit einer Länge, die fünftausendmal bis einzehntelmal so groß wie die Wurzel aus der Querschnitssfläche des mindestens einen Kanals ist. Der Kanal einer Ausgestaltung ist teilweise durch eine spiralförmige Nut an einer Außenseite des Au ßenbehälters gebildet.Out DE 198 51 404 A1 a pressure equalizing device for a double container is known, wherein a channel between an inner container and an outer container is provided, with a cross-sectional area whose root is from 10 to 500 microns, and with a length which is five thousand times to one-tenth times as large as the root of the Querschnitssfläche at least one channel. The channel of an embodiment is partially formed by a spiral groove on an outer side of the Au ßenbehälters.

Aufgabe und LösungTask and solution

Aufgabe der Erfindung ist es, eine Gestaltung für eine gattungsgemäße Austragvorrichtung zur Verfügung zu stellen, durch die dieser nachteilige Diffusionsprozess verhindert oder vermindert wird.The object of the invention is to provide a design for a generic discharge device, by which this disadvantageous diffusion process is prevented or reduced.

Gemäß der Erfindung ist vorgesehen, dass der Aufnahmeraum mit einer Umgebungsatmosphäre zum Zwecke des Druckausgleichs durch mindestens einen Kapillarkanal verbunden ist.According to the invention it is provided that the receiving space is connected to an ambient atmosphere for the purpose of pressure equalization by at least one capillary channel.

Ein solcher Kapillarkanal weist eine dünne und langgestreckte Gestaltung auf und mündet mit seinem einem Ende im Aufnahmeraum und mit seinem anderen Ende im Bereich der Umgebungsatmosphäre. Somit besteht zwar eine Druckausgleichsmöglichkeit zwischen dem Aufnahmeraum einerseits und der Umgebungsatmosphäre andererseits, aufgrund der Gestaltung der Verbindung als Kapillarkanal kommt es jedoch dennoch zu einer Sättigung der Luft im Aufnahmeraum mit Flüssigkeit, die ein weiteres Herausdiffundieren von Flüssigkeit aus dem Flüssigkeitsspeicher verhindert, wenn die Austragvorrichtung für längere Zeit nicht benutzt wird. Im Kapillarkanal bildet sich ein stabiler Gradient hinsichtlich der Luftfeuchtigkeit.Such a capillary channel has a thin and elongate shape and opens with its one end in the receiving space and with its other end in the region of the ambient atmosphere. Thus, although there is a pressure equalization possibility between the receiving space on the one hand and the ambient atmosphere on the other hand, but due to the design of the compound as a capillary channel, it comes nonetheless saturates the air in the receiving space with liquid which prevents further outdiffusion of liquid from the liquid storage when the discharge device is not used for an extended period of time. The capillary channel forms a stable gradient in terms of humidity.

Als Kapillarkanal im Sinne dieser Erfindung werden nur Kanalabschnitte angesehen, die eine Querschnittsfläche kleiner 1 mm2 aufweisen. Um das Entweichen der Luftfeuchtigkeit im Aufnahmeraum zu verhindern und die Ausbildung eines stabilen Gradienten zu gewährleisten, wird es als besonders vorteilhaft angesehen, wenn ein Quotient aus der Länge des Kapillarkanals geteilt durch dessen mittlere Querschnittsfläche größer als 300 mm-1 ist, insbesondere größer als 1000 mm-1 ist. Ein Quotient von mindestens 2500 mm-1 wird als besonders vorteilhaft angesehen. Ein Kapillarkanal mit einer mittleren Querschnittsfläche von 0,03 mm2 hat erfindungsgemäß somit eine Länge von mindestens etwa 10 mm aufzuweisen.As a capillary channel in the context of this invention, only channel sections are considered, which have a cross-sectional area less than 1 mm 2 . In order to prevent the escape of humidity in the receiving space and to ensure the formation of a stable gradient, it is considered particularly advantageous if a quotient of the length of the capillary channel divided by its average cross-sectional area is greater than 300 mm -1 , in particular greater than 1000 mm -1 . A quotient of at least 2500 mm -1 is considered to be particularly advantageous. A capillary channel with an average cross-sectional area of 0.03 mm 2 according to the invention thus has to have a length of at least about 10 mm.

Jenseits des reinen Verhältnisses der Querschnittsfläche zur Länge hat es sich als besonders vorteilhaft herausgestellt, wenn die Querschnittsfläche besonders klein ist, insbesondere kleiner als 0,05 mm2, vorzugsweise kleiner als 0,02 mm2 und im Idealfall kleiner als 0,01 mm2. Weiterhin hat es sich herausgestellt, dass die Länge des Kapillarkanals vorzugsweise mindestens 10 mm betragen sollte, insbesondere mindestens 30 mm oder gar mindestens 50 mm.Beyond the pure ratio of the cross-sectional area to the length, it has proven to be particularly advantageous if the cross-sectional area is particularly small, in particular less than 0.05 mm 2 , preferably less than 0.02 mm 2 and ideally less than 0.01 mm 2 , Furthermore, it has been found that the length of the capillary channel should preferably be at least 10 mm, in particular at least 30 mm or even at least 50 mm.

Der Kapillarkanal ist zumindest abschnittsweise durch eine nutartige Vertiefung in einer Außenseite des Flüssigkeitsspeichers gebildet. Diese nutartige Vertiefung ist einfach herzustellen. Der Kapillarkanal kann dann durch Anlegen der Außenseite bzw. der Innenseite an einem Gegenbauteil umfänglich geschlossen werden. Besonders von Vorteil ist es, wenn der Kapillarkanal in dem durch eine nutartige Vertiefung gebildeten Bereich gemeinsam von dem Aufnahmegehäuse einerseits und dem Flüssigkeitsspeicher andererseits umfänglich verschlossen wird. Hierdurch ergibt sich eine kostengünstige und einfache Bauweise. Hinzu kommt, dass das flexible Material, welches für den Flüssigkeitsspeicher zu verwenden ist, für eine umfängliche Abdichtung des Kapillarkanals besonders gut geeignet ist. Als Außenseite des Flüssigkeitsspeichers wird eine Fläche angesehen, die bestimmungsgemäß mit der im Flüssigkeitsspeicher gespeicherten Flüssigkeit nicht in Kontakt kommt. Der Bereich, in dem der Kapillarkanal in die Außenseite des Flüssigkeitsspeichers eingebracht ist, weist vorzugsweise eine gegenüber dem bestimmungsgemäß sich verformenden Teil des Flüssigkeitsspeichers vergrößerte Wandstärke auf.The capillary channel is at least partially formed by a groove-like depression in an outer side of the liquid reservoir. This groove-like depression is easy to manufacture. The capillary channel can then be closed by applying the outside or the inside of a counter component circumferentially. It is particularly advantageous if the capillary channel formed in the by a groove-like depression Area is jointly circumferentially closed by the receiving housing on the one hand and the liquid storage on the other hand. This results in a cost-effective and simple construction. In addition, the flexible material, which is to be used for the liquid storage, is particularly well suited for a circumferential sealing of the capillary channel. The outer side of the liquid reservoir is considered to be a surface that does not come into contact with the liquid stored in the liquid reservoir as intended. The region in which the capillary channel is introduced into the outside of the liquid reservoir, preferably has a relative to the intended deforming part of the liquid storage increased wall thickness.

Um einen besonders langen Kapillarkanal zu schaffen, wird es als vorteilhaft angesehen, wenn die nutartige Vertiefung sich zumindest abschnittsweise tangential oder spiralförmig an der Außenseite des Flüssigkeitsspeichers oder an der Innenseite des Aufnahmegehäuses erstreckt. Eine solche Gestaltung erstattet es, auf einfache Weise Kapillarkanäle von mehr als 50 mm Länge auch bei kleinen Austragvorrichtungen von beispielsweise weniger als 20 mm Durchmesser zu erzielen.In order to create a particularly long capillary channel, it is considered advantageous if the groove-like depression extends at least in sections tangentially or spirally on the outside of the liquid reservoir or on the inside of the receiving housing. Such a design makes it easy to achieve capillary channels of more than 50 mm in length even with small discharge devices of, for example, less than 20 mm in diameter.

Wie oben bereits erwähnt ist die Wandung des Aufnahmegehäuses dicker als die Wandung des Flüssigkeitsspeichers, so dass eine Diffusion durch diese Wandung nicht oder nicht in relevantem Maße stattfindet. Um die Diffusionsneigung weiter zu reduzieren, kann es von Vorteil sein, wenn das Aufnahmegehäuse zumindest abschnittsweise eine Wandung aufweist, die aus einem Material mit geringer Diffusionsrate besteht, insbesondere aus Metall, Keramik oder Glas.As already mentioned above, the wall of the receiving housing is thicker than the wall of the liquid reservoir, so that diffusion through this wall does not take place or does not take place to a relevant extent. In order to further reduce the tendency to diffusion, it may be advantageous if the receiving housing has, at least in sections, a wall which consists of a material with a low diffusion rate, in particular of metal, ceramic or glass.

Weiterhin wird es als vorteilhaft angesehen, wenn an dem als Flüssigkeitsbeutel ausgebildeten Flüssigkeitsspeicher ein radial nach außen weisender Steg vorgesehen ist, der zwischen dem Aufnahmegehäuse und einem davon getrennten und die Fördereinrichtung beinhaltenden Gehäuseteil als Dichtung angeordnet ist. Dieser Steg übernimmt dann eine Doppelfunktion als Dichtung. Zum einen dichtet er den nicht vom Flüssigkeitsspeicher eingenommenen Bereich des Aufnahmeraums gegenüber der Umgebungsatmosphäre ab. Zum anderen bildet er eine Dichtung im Übergangsbereich zwischen dem Flüssigkeitsspeicher und der Fördereinrichtung gegenüber einer Umgebungsatmosphäre. Bei der zweiten und der dritten Variante der Erfindung kann vorgesehen sein, dass der Steg durch den Kapillarkanal oder den Druckausgleichskanal unterbrochen ist und nur in den Bereichen jenseits dieser Unterbrechung die Dichtungsfunktion übernimmt.Furthermore, it is considered advantageous if a radially outwardly pointing web is provided on the liquid reservoir formed as a liquid bag, which between the receiving housing and a separate and containing the conveyor housing part is arranged as a seal. This bridge then takes on a dual function as a seal. On the one hand, it seals off the region of the receiving space not occupied by the liquid reservoir from the ambient atmosphere. On the other hand, it forms a seal in the transition region between the liquid reservoir and the conveyor with respect to an ambient atmosphere. In the second and the third variant of the invention can be provided that the web is interrupted by the capillary channel or the pressure equalization channel and takes over the sealing function only in the areas beyond this interruption.

Kurzbeschreibung der ZeichnungenBrief description of the drawings

Weitere Aspekte und Vorteile der Erfindung ergeben sich außer aus den Ansprüchen auch aus der nachfolgenden Beschreibung bevorzugter Ausführungsbeispiele der Erfindung, die nachfolgend anhand der Figuren erläutert sind. Dabei zeigen:

Fig. 1a und 1b
eine Ausführungsform einer Austragvorrichtung,
Fig. 2a, 2b und 3
eine erste Ausführungsform einer erfindungsgemäßen Austragvorrichtung und
Fig. 4a, 4b, und 5
eine zweite Ausführungsform einer erfindungsgemäßen Austragvorrichtung.
Other aspects and advantages of the invention will become apparent from the claims and from the following description of preferred embodiments of the invention, which are explained below with reference to the figures. Showing:
Fig. 1a and 1b
an embodiment of a discharge device,
Fig. 2a, 2b and 3
a first embodiment of a discharge device according to the invention and
FIGS. 4a, 4b, and 5
A second embodiment of a discharge device according to the invention.

Detaillierte Beschreibung der AusführungsbeispieleDetailed description of the embodiments

Die in den Figuren dargestellten Austragvorrichtungen sind jeweils als tragbare, mobile Austragvorrichtungen ausgebildet und weisen als übereinstimmende Merkmale jeweils eine manuell betätigbaren Fördereinrichtung 10 auf, deren Eingangsseite 10a mit einem Flüssigkeitsspeicher 20 verbunden ist und deren Ausgangsseite 10b mit einer Austragsöffnung 12 verbunden ist. Im Falle der Ausführungsform der Fig. 1 bis 3 ist die Fördereinrichtung 10 als Kolbenpumpe ausgebildet. Im Falle der Ausführungsformen der Fig. 4 ist die Fördereinrichtung 10 als Balgpumpe ausgebildet. Weiterhin stimmen alle Ausführungsformen dahingehend überein, dass der Flüssigkeitsspeicher 20 als Flüssigkeitsbeutel ausgebildet ist, der formflexibel ist, so dass er sich hinsichtlich seines Innenvolumens jeweils der noch im Flüssigkeitsspeicher 20 befindlichen Menge der auszutragenden Flüssigkeit 30 anpassen kann. Allen Austragvorrichtungen der Ausführungsform ist darüber hinaus gemein, dass der beutelartige Flüssigkeitsspeicher 20 in einem durch ein Aufnahmegehäuse 40 gebildeten Aufnahmeraum 42 angeordnet ist und somit gegen mechanische Einflüsse von außen geschützt ist.The discharge devices shown in the figures are each designed as portable, mobile discharge devices and each have a manually operable conveyor as matching features 10, whose input side 10a is connected to a liquid reservoir 20 and whose output side 10b is connected to a discharge opening 12. In the case of the embodiment of Fig. 1 to 3 the conveyor 10 is designed as a piston pump. In the case of embodiments of the Fig. 4 the conveyor 10 is designed as a bellows pump. Furthermore, all embodiments agree that the liquid reservoir 20 is designed as a fluid bag that is dimensionally flexible, so that it can in terms of its internal volume of each still in the liquid storage 20 located amount of liquid to be discharged 30 adapt. All discharge devices of the embodiment is also common that the bag-like liquid storage 20 is arranged in a receiving space 42 formed by a receiving housing 40 and is thus protected against mechanical influences from the outside.

Zu den Ausführungsformen im Einzelnen:To the embodiments in detail:

Fig. 1a stellt eine nicht erfindungsgemäßen Ausführungsform in einem Lieferzustand dar. In diesem Lieferzustand weist der Flüssigkeitsspeicher 20 sein maximales Volumen auf, wobei dieses Volumen so bemessen ist, dass der Flüssigkeitsspeicher 20 den Aufnahmeraum 42 nur etwa zu 50% ausfüllt. Der nicht vom Flüssigkeitsspeicher eingenommene Teil 42a des Aufnahmeraums 42 ist in diesem Lieferzustand mit Luft gefüllt, die in etwa unter Umgebungsdruck (1 bar) steht. Fig. 1a represents a non-inventive embodiment in a delivery state. In this delivery state, the liquid reservoir 20 has its maximum volume, wherein this volume is dimensioned so that the liquid reservoir 20 fills the receiving space 42 only about 50%. The portion 42a of the receiving space 42 not occupied by the liquid store is filled with air in this delivery condition, which is approximately at ambient pressure (1 bar).

Der Flüssigkeitsspeicher 20 ist bei dieser wie auch bei allen anderen Ausführungsformen lediglich mit der Fördereinrichtung 10 verbunden, so dass die Flüssigkeit 30 im Flüssigkeitsspeicher 20 zumindest in flüssiger Form nur in Richtung der Fördereinrichtung 10 aus dem Flüssigkeitsspeicher 20 entweichen kann. Auch ist wie ebenfalls bei allen dargestellten Ausführungsformen bei der Ausführungsform der Fig. 1a und 1b vorgesehen, dass keine Möglichkeit für Umgebungsluft einer Umgebungsatmosphäre 1 besteht, in den Flüssigkeitsspeicher 20 selbst einzudringen. Die Abdichtung des Flüssigkeitsspeichers 20 nach außen erfolgt über einen am oberen Ende des Flüssigkeitsspeichers 20 vorgesehenen umlaufenden Kragen 22, der zwischen einem oberen Rand 44 des Aufnahmegehäuses 40 und einem Fördereinrichtungsgehäuse 14 eingeklemmt ist und so als Dichtung agiert.The liquid reservoir 20 is connected in this as well as in all other embodiments only with the conveyor 10, so that the liquid 30 can escape in the liquid reservoir 20 at least in liquid form only in the direction of the conveyor 10 from the liquid reservoir 20. Also, as well as in all the illustrated embodiments in the embodiment of Fig. 1a and 1b provided that no possibility for ambient air of an ambient atmosphere 1 is to penetrate into the liquid storage 20 itself. The sealing of the liquid reservoir 20 to the outside via a provided at the upper end of the liquid reservoir 20 circumferential collar 22 which is clamped between an upper edge 44 of the receiving housing 40 and a conveyor housing 14 and acts as a seal.

Diese Dichtung bewirkt darüber hinaus bei der Ausführungsform der Fig. 1a und 1b auch, dass der mit Luft gefüllte Teil 42a des Aufnahmeraums 42 gasdicht gegenüber einer Umgebung 1 abgeschlossen ist, so dass weder in den Flüssigkeitsspeicher 20 noch in den nicht vom Flüssigkeitsspeicher 20 eingenommenen Teil 42a des Aufnahmeraums 42 Luft von außen eindringen kann.This seal also causes in the embodiment of the Fig. 1a and 1b Also, that the air-filled part 42a of the receiving space 42 is gas-tight with respect to an environment 1 is completed, so that neither in the liquid reservoir 20 still in the not occupied by the liquid reservoir 20 part 42a of the receiving space 42 air can penetrate from the outside.

Wenn die Austragvorrichtung der Fig. 1a und 1b in Betrieb genommen wird, indem durch manuelle Betätigung der Fördereinrichtung 10 über die Betätigungshandhabe 16 Flüssigkeit 30 ausgetragen wird, verringert sich das Innenvolumen des Flüssigkeitsspeichers 20, während der umgebende Teil 42a des Aufnahmeraums 42 zwangsläufig vergrößert wird. Da keinerlei Luft nachströmen kann, führt dies schrittweise zu einer Absenkung des Drucks im Aufnahmeraum 42, wobei diese Druckverringerung aufgrund der Tatsache, das bereits im Lieferzustand der Fig. 1a eine erhebliche Luftmenge im Aufnahmeraum 42 vorhanden war, nur gering ausfällt. Bei vollständiger Entleerung des Flüssigkeitsspeichers 20 beträgt der Druck im Aufnahmeraum etwa 0,5 bar. Da die Fördereinrichtung 10 so ausgebildet ist, dass sie gegen einen solchen Unterdruck arbeiten kann, bleibt die Funktionstüchtigkeit der Austragvorrichtung stets gegeben.If the discharge of the Fig. 1a and 1b is put into operation by liquid 16 is discharged by manual operation of the conveyor 10 via the actuating handle 16, the inner volume of the liquid reservoir 20 decreases, while the surrounding part 42a of the receiving space 42 is inevitably increased. Since no air can flow, this gradually leads to a reduction in the pressure in the receiving space 42, this pressure reduction due to the fact that already in the delivery state of the Fig. 1a a considerable amount of air in the receiving space 42 was present, only small fails. Upon complete emptying of the liquid reservoir 20, the pressure in the receiving space is about 0.5 bar. Since the conveyor 10 is designed so that it can work against such a negative pressure, the functionality of the discharge device is always given.

Fig. 1b zeigt einen Zwischenzustand, in dem etwa die Hälfte der Flüssigkeit 30 entnommen wurde und im Aufnahmeraum 42 ein Druck von etwa 0,8bar, also ein Unterdruck gegenüber der Umgebung von etwa 0,2 bar, besteht. Fig. 1b shows an intermediate state in which about half of the liquid 30 has been removed and in the receiving space 42, a pressure of about 0.8 bar, that is, a negative pressure relative to the environment of about 0.2 bar exists.

Die vollständige Isolierung des Aufnahmeraums 42 gegenüber der Umgebung1 führt bei dieser Gestaltung der Fig. 1a und 1b dazu, dass nur geringe Mengen der Flüssigkeit 30 durch Diffusion in den Teil 42a des Aufnahmeraums 42 durch die Wandung des Flüssigkeitsspeichers 20 hindurch gelangen können. Im Teil 42a kommt es recht schnell zu einer Sättigung der Luft, die diesen Diffusionsprozess beendet. Da die gesättigte Luft aufgrund der gasdichten Isolierung des Aufnahmeraums 42 gegenüber der Außenumgebung 1 nicht entweichen kann, kann somit nur ein geringer Teil der Flüssigkeit 30 in den Teil 42a des Aufnahmeraums 42 gelangen.The complete isolation of the receiving space 42 from the environment 1 leads in this design of the Fig. 1a and 1b In addition, only small amounts of the liquid 30 can pass through diffusion into the part 42a of the receiving space 42 through the wall of the liquid store 20. In part 42a, saturation of the air, which terminates this diffusion process, occurs quite quickly. Since the saturated air due to the gas-tight insulation of the receiving space 42 with respect to the external environment 1 can not escape, so only a small part of the liquid 30 can get into the part 42 a of the receiving space 42.

Die erste Ausführungsform der Erfindung gemäß Fig. 2a und 2b weist weitgehende Übereinstimmung mit der Ausführungsform der Fig. 1a und 1b auf. Abweichend von der ersten Gestaltung ist jedoch ein Kapillarkanal 60 vorgesehen, der sich in einem Abschnitt 60a von der Umgebungsatmosphäre 1 bis zum Kragen 22 des Flüssigkeitsspeichers 20 erstreckt. In diesem Kragen 22 ist, wie in Fig. 3 dargestellt ist, eine Nut eingebracht, die einen nach außen weisenden Abschnitt 60b, einen tangential verlaufenden Abschnitt 60c sowie einen nach innen radial weisenden Abschnitt 60d des Kapillarkanals 60 bildet. Diese Nut wird an ihrer offenen Seite durch den Kragen 44 des Aufnahmegehäuses 40 geschlossen. Durch den Kapillarkanal hindurch kann Luft in den Teil 42a des Aufnahmeraums 42 gelangen, so dass bei fortschreitender Entleerung des Flüssigkeitsspeichers 20 ein Druckausgleich stattfinden kann. Im Aufnahmeraum 42 stellt sich nach einer jeden Betätigung der Austragvorrichtung somit nach kurzer Zeit wieder der Umgebungsdruck von etwa 1bar ein. Der Weg der Luft durch den Kapillarkanal 60 ist in Fig. 1b durch den gepunktet dargestellten Pfeil 2 verdeutlicht.The first embodiment of the invention according to Fig. 2a and 2b has broad agreement with the embodiment of the Fig. 1a and 1b on. Deviating from the first embodiment, however, a capillary channel 60 is provided, which extends in a portion 60 a from the ambient atmosphere 1 to the collar 22 of the liquid reservoir 20. In this collar 22 is as in Fig. 3 is shown, a groove is formed, which forms an outwardly facing portion 60 b, a tangential portion 60 c and an inwardly radially pointing portion 60 d of the capillary channel 60. This groove is closed at its open side by the collar 44 of the receiving housing 40. Air can pass through the capillary channel into the part 42a of the receiving space 42, so that pressure can equalize as the liquid reservoir 20 progresses. In the receiving space 42, after each actuation of the discharge thus after a short time, the ambient pressure of about 1bar again. The path of the air through the capillary channel 60 is in Fig. 1b illustrated by the dotted arrow 2.

Somit ist bei dieser Gestaltung der Fig. 2a, 2b und 3 eine Verbindung zwischen der Umgebungsatmosphäre 1 und dem Aufnahmeraum 42 gegeben. Diese Verbindung führt jedoch aufgrund der Gestaltung der Verbindung als Kapillarkanal 60 nicht dazu, dass die aus dem Flüssigkeitsspeicher 20 in den vom Flüssigkeitsspeicher 20 nicht eingenommenen Teil 42a des Aufnahmeraums 42 diffundierte Flüssigkeit in die Umgebung 1 entweichen kann. Stattdessen stellt sich ein stabiler Gradient im Kapillarkanal 60 zwischen der gesättigten Luft im Teil 42a und der Luft in der Umgebungsatmosphäre 1 ein, der die aus dem Flüssigkeitsspeicher 20 herausdiffundierte Flüssigkeit 30 aus dem Teil 42a nur in unerheblicher Menge aus dem Aufnahmeraum 42 entweichen lässt.Thus, in this design of Fig. 2a, 2b and 3 a connection between the ambient atmosphere 1 and the receiving space 42 given. However, due to the design of the connection as capillary channel 60, this connection does not cause the liquid diffused from the liquid store 20 to escape into the environment 1 into the part 42a of the receiving space 42 not occupied by the liquid store 20. Instead, a stable gradient in the capillary channel 60 is established between the saturated air in the part 42a and the air in the ambient atmosphere 1, which allows the liquid 30 diffused out of the liquid reservoir 20 to escape from the receiving space 42 only to a negligible extent.

Die Ausführungsform der Fig. 4 und 5 zeigt einen vom Grundaufbau gegenüber den vorangegangenen Ausführungsformen deutlich abweichenden Spender, der jedoch ein ähnliches Grundprinzip hinsichtlich der Belüftung des nicht vom Flüssigkeitsspeicher 20 eingenommenen Teils 42a des Aufnahmeraums 42 aufweist. Auch hier ist ein Kapillarkanal 62 vorgesehen, dessen erster Abschnitt 62a zwischen zwei Gehäuseabschnitten 14, 40 verläuft. Daran schließt sich ein Abschnitt 62b des Kapillarkanals an, der als spiralförmige Nut an der Außenseite des Flüssigkeitsspeichers 20 ausgebildet ist und dessen offene Seite durch die Innenseite des Au ßengehäuses 40 verschlossen ist.The embodiment of the 4 and 5 shows a significantly different from the basic structure compared to the previous embodiments dispenser, but has a similar basic principle with respect to the ventilation of not occupied by the liquid reservoir 20 portion 42a of the receiving space 42. Again, a capillary channel 62 is provided, the first portion 62 a between two housing sections 14, 40 extends. This is followed by a section 62b of the capillary channel, which is formed as a helical groove on the outside of the liquid reservoir 20 and whose open side is closed by the inside of the Au ßengehäuses 40.

Die Funktionsweise dieses Kapillarkanals 62 stimmt mit der Funktionsweise des Kapillarkanals 60 der Ausführungsform der Fig. 2a, 2b und 3 überein. Die Luft aus der Umgebung 1 kann entlang des gepunkteten Pfeils 4 in den Aufnahmeraum 42 eindringen. Die Besonderheit liegt hier insbesondere in der großen Länge des Kapillarkanals 62 durch die spiralförmige Gestaltung.The operation of this capillary channel 62 is consistent with the operation of the capillary channel 60 of the embodiment of Fig. 2a, 2b and 3 match. The air from the environment 1 can penetrate along the dotted arrow 4 in the receiving space 42. The peculiarity lies here in particular in the large length of the capillary channel 62 by the spiral-shaped design.

Claims (6)

  1. A discharging device for liquids, more particularly for pharmaceutical liquids, comprising
    - a feeding device (10),
    - a liquid storage reservoir (20) for storing a liquid (30) connected to an input side (10a) of the feeding device (10), and
    - a discharge orifice (12) connected to an output side (10b) of the feeding device (10),
    wherein
    - said liquid storage reservoir (20) is at least in sections in the form of a dimensionally flexible liquid-containing bag (20),
    - said liquid storage reservoir (20) is disposed in a constant volume accommodation chamber (42),
    characterized in that
    the accommodation chamber (42) is permanently connected to an environmental atmosphere (1) for the purpose of pressure compensation through at least one capillary channel (60; 62) which has an elongated, narrow design, and
    said capillary channel (60; 62) is at least in sections provided by a groove-type recess (60b, 62c, 60; 62b) on an outer side of the liquid storage reservoir (20).
  2. The discharging device according to claim 1, characterized in that
    - the quotient of the length of said capillary channel (60; 62) divided by the average cross-sectional area is greater than 300 mm-1, more particularly greater than 1000 mm-1,
    - the average cross-sectional area of said capillary channel (60; 62) is less than 0.05 mm2, preferably less than 0.02 mm2, in particular preferably less than 0.01 mm2,
    and/or
    - the length of said capillary channel (60; 62) is greater than 10 mm, preferably greater than 30 mm, in particular preferably greater than 50 mm.
  3. The discharging device according to any one of the claims 1 or 2, characterized in that said capillary channel (60; 62) in the section of the groove-type recess is jointly sealed off by an accommodation housing (40) and said liquid storage reservoir (20) all round.
  4. The discharging device according to any one of the claims 1 to 3, characterized in that the groove-type recess (60; 62) extends at least in sections tangentially or helically on the outer side of the liquid storage reservoir (20).
  5. The discharging device according to any one of the preceding claims, characterized in that the accommodation chamber (42) is confined in relation to the environment by a wall made of a material displaying a low diffusion rate, in particular made of metal, ceramics or glass.
  6. The discharging device according to any one of the preceding claims, characterized in that a radially outwardly oriented fin (22) is provided on the liquid storage reservoir (20), which fin is disposed as a sealing between the accommodation housing (40) and a housing part (14) including the feeding device (10).
EP10011452.9A 2009-10-23 2010-09-29 Dispenser Active EP2314380B1 (en)

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EP3103498B1 (en) 2015-06-12 2018-08-01 AP Pharma Systems Atomizadores e Dispensadores Ltda Spray dispenser for nasal drugs
US11224702B2 (en) 2015-06-12 2022-01-18 Ap Pharma Systems Atomizadores E Dispensadores Ltda Spray dispenser for nasal drugs

Also Published As

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EP2314380A2 (en) 2011-04-27
JP2011088676A (en) 2011-05-06
US9700907B2 (en) 2017-07-11
DE102009051570B3 (en) 2011-06-22
US20110095053A1 (en) 2011-04-28
EP2314380A3 (en) 2011-12-14

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