EP2294312A4 - Système de radiothérapie - Google Patents

Système de radiothérapie

Info

Publication number
EP2294312A4
EP2294312A4 EP20090768670 EP09768670A EP2294312A4 EP 2294312 A4 EP2294312 A4 EP 2294312A4 EP 20090768670 EP20090768670 EP 20090768670 EP 09768670 A EP09768670 A EP 09768670A EP 2294312 A4 EP2294312 A4 EP 2294312A4
Authority
EP
European Patent Office
Prior art keywords
radiation therapy
therapy system
radiation
therapy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP20090768670
Other languages
German (de)
English (en)
Other versions
EP2294312A1 (fr
EP2294312B1 (fr
Inventor
Marco Carlone
Gino B Fallone
Brad Murray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alberta Health Services
Original Assignee
Alberta Health Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alberta Health Services filed Critical Alberta Health Services
Publication of EP2294312A1 publication Critical patent/EP2294312A1/fr
Publication of EP2294312A4 publication Critical patent/EP2294312A4/fr
Application granted granted Critical
Publication of EP2294312B1 publication Critical patent/EP2294312B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1064Monitoring, verifying, controlling systems and methods for adjusting radiation treatment in response to monitoring
    • A61N5/1065Beam adjustment
    • A61N5/1067Beam adjustment in real time, i.e. during treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1049Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/32Excitation or detection systems, e.g. using radio frequency signals
    • G01R33/34Constructional details, e.g. resonators, specially adapted to MR
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/38Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field
    • G01R33/385Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field using gradient magnetic field coils
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/4808Multimodal MR, e.g. MR combined with positron emission tomography [PET], MR combined with ultrasound or MR combined with computed tomography [CT]
    • G01R33/4812MR combined with X-ray or computed tomography [CT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1049Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1055Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using magnetic resonance imaging [MRI]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/38Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field
    • G01R33/3806Open magnet assemblies for improved access to the sample, e.g. C-type or U-type magnets
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E10/00Energy generation through renewable energy sources
    • Y02E10/30Energy from the sea, e.g. using wave energy or salinity gradient

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Animal Behavior & Ethology (AREA)
  • Theoretical Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Radiation-Therapy Devices (AREA)
EP09768670.3A 2008-06-24 2009-06-25 Système de radiothérapie Active EP2294312B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12941108P 2008-06-24 2008-06-24
PCT/CA2009/000873 WO2009155700A1 (fr) 2008-06-24 2009-06-25 Système de radiothérapie

Publications (3)

Publication Number Publication Date
EP2294312A1 EP2294312A1 (fr) 2011-03-16
EP2294312A4 true EP2294312A4 (fr) 2011-07-20
EP2294312B1 EP2294312B1 (fr) 2016-04-27

Family

ID=41443944

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09768670.3A Active EP2294312B1 (fr) 2008-06-24 2009-06-25 Système de radiothérapie

Country Status (8)

Country Link
US (2) US8983573B2 (fr)
EP (1) EP2294312B1 (fr)
JP (1) JP5486596B2 (fr)
CN (1) CN102215912B (fr)
AU (1) AU2009261910C1 (fr)
CA (1) CA2728111C (fr)
HK (1) HK1154360A1 (fr)
WO (1) WO2009155700A1 (fr)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2556934C (fr) 2004-02-20 2018-05-22 James F. Dempsey Systeme d'administration d'une therapie de radiation conformee pendant l'imagerie simultanee de tissu mou
GB2427479B (en) * 2005-06-22 2007-11-14 Siemens Magnet Technology Ltd Particle Radiation Therapy Equipment and method for performing particle radiation therapy
US20100174172A1 (en) * 2009-01-07 2010-07-08 Moshe Ein-Gal Mri system for upright radiotherapy
CN102472830B (zh) 2009-07-15 2016-03-30 微雷公司 用于使直线性加速器和磁共振成像设备彼此屏蔽的方法和装置
WO2011041750A1 (fr) 2009-10-01 2011-04-07 Loma Linda University Medical Centre Détecteur d'ionisation à impacts induits par les ions et utilisations de celui-ci
KR101284171B1 (ko) * 2009-12-18 2013-07-10 한국전자통신연구원 양성자를 이용한 치료 장치 및 이를 이용한 치료 방법
DE102010001746B4 (de) * 2010-02-10 2012-03-22 Siemens Aktiengesellschaft Vorrichtung mit einer Kombination aus einer Magnetresonanzvorrichtung und einer Strahlentherapievorrichtung
US9694205B2 (en) * 2010-02-12 2017-07-04 Elekta Ab (Publ) Radiotherapy and imaging apparatus
US20110201920A1 (en) * 2010-02-12 2011-08-18 Elekta Ab (Publ) Radiotherapy and imaging apparatus
EP2558162B1 (fr) * 2010-04-15 2020-06-10 Elekta AB (PUBL) Appareil de radiothérapie et d'imagerie
US8710843B2 (en) 2010-04-27 2014-04-29 University Health Network Magnetic resonance imaging apparatus for use with radiotherapy
CN103210318B (zh) * 2010-11-09 2019-04-23 皇家飞利浦电子股份有限公司 具有至少两个发射和接收信道的磁共振成像以及放射治疗设备
US9608395B2 (en) * 2010-12-08 2017-03-28 Koninklijke Philips N.V. Slip ring assembly
DE102011006582A1 (de) * 2011-03-31 2012-10-04 Siemens Aktiengesellschaft Strahlentherapieanlage mit Hochfrequenzschirmung
ES2523825T3 (es) 2011-06-15 2014-12-01 Imris Inc. Integración de IRM en tratamiento con radioterapia
US9155913B2 (en) * 2011-08-02 2015-10-13 The Board Of Trustees Of The Leland Stanford Junior University Robotic linac adaptation (RLA) for the in-line MRI-linac configuration
US8981779B2 (en) 2011-12-13 2015-03-17 Viewray Incorporated Active resistive shimming fro MRI devices
US10561861B2 (en) 2012-05-02 2020-02-18 Viewray Technologies, Inc. Videographic display of real-time medical treatment
EP2877089B1 (fr) * 2012-07-27 2022-05-18 University Health Network Système de radiothérapie intégrant une source de rayonnement avec un appareil d'imagerie par résonance magnétique avec des composants d'aimant mobiles
JP6382208B2 (ja) 2012-10-26 2018-08-29 ビューレイ・テクノロジーズ・インコーポレイテッドViewRay Technologies, Inc. システム及びコンピュータプログラム製品
GB2507585B (en) 2012-11-06 2015-04-22 Siemens Plc MRI magnet for radiation and particle therapy
EP2774537A1 (fr) 2013-03-08 2014-09-10 Imris Inc. Alignement de patient dans une radiothérapie guidée par IRM
US9446263B2 (en) 2013-03-15 2016-09-20 Viewray Technologies, Inc. Systems and methods for linear accelerator radiotherapy with magnetic resonance imaging
CN111228657A (zh) * 2015-09-10 2020-06-05 上海联影医疗科技有限公司 一种磁共振图像引导的放射治疗***
US10252083B2 (en) * 2015-09-23 2019-04-09 Varian Medical Systems Inc. Systems, methods, and devices for high-energy irradiation
DE102016100638B4 (de) 2016-01-15 2024-06-06 Helmholtz-Zentrum Dresden - Rossendorf E. V. Verfahren und Vorrichtung
US10413751B2 (en) 2016-03-02 2019-09-17 Viewray Technologies, Inc. Particle therapy with magnetic resonance imaging
US9855445B2 (en) 2016-04-01 2018-01-02 Varian Medical Systems, Inc. Radiation therapy systems and methods for delivering doses to a target volume
US11378629B2 (en) 2016-06-22 2022-07-05 Viewray Technologies, Inc. Magnetic resonance imaging
WO2018023195A1 (fr) 2016-07-31 2018-02-08 Alberta Health Services Système de radiothérapie guidée par irm-pet en temps réel avec vérification de dépôt de dose
CA3072835A1 (fr) 2016-09-26 2018-03-29 Alberta Health Services Radiochirurgie stereotaxique guidee par resonance magnetique
RU2019121943A (ru) 2016-12-13 2021-01-15 Вьюрэй Текнолоджиз, Инк. Системы и способы лучевой терапии
US10775460B2 (en) 2017-06-28 2020-09-15 Alberta Health Services Image guided radiation therapy system
US10183179B1 (en) 2017-07-21 2019-01-22 Varian Medical Systems, Inc. Triggered treatment systems and methods
US10549117B2 (en) 2017-07-21 2020-02-04 Varian Medical Systems, Inc Geometric aspects of radiation therapy planning and treatment
US11712579B2 (en) 2017-07-21 2023-08-01 Varian Medical Systems, Inc. Range compensators for radiation therapy
US11590364B2 (en) 2017-07-21 2023-02-28 Varian Medical Systems International Ag Material inserts for radiation therapy
US10843011B2 (en) 2017-07-21 2020-11-24 Varian Medical Systems, Inc. Particle beam gun control systems and methods
US10092774B1 (en) 2017-07-21 2018-10-09 Varian Medical Systems International, AG Dose aspects of radiation therapy planning and treatment
EP3710111B1 (fr) 2017-11-16 2021-12-29 Varian Medical Systems, Inc. Sortie de faisceau améliorée et mise en forme de champ dynamique destinés à un système de radiothérapie
US11033758B2 (en) 2017-12-06 2021-06-15 Viewray Technologies, Inc. Radiotherapy systems, methods and software
US11209509B2 (en) 2018-05-16 2021-12-28 Viewray Technologies, Inc. Resistive electromagnet systems and methods
US20210299462A1 (en) 2018-06-18 2021-09-30 National Institutes For Quantum And Radiological Science And Technology Particle beam irradiation system, particle beam irradiation method, irradiatiion planning program, irradiation planning device, electromagnetic field generator, and irradiation device
US10910188B2 (en) 2018-07-25 2021-02-02 Varian Medical Systems, Inc. Radiation anode target systems and methods
CN114796894A (zh) 2018-11-14 2022-07-29 上海联影医疗科技股份有限公司 放射治疗***
US10814144B2 (en) 2019-03-06 2020-10-27 Varian Medical Systems, Inc. Radiation treatment based on dose rate
US10918886B2 (en) 2019-06-10 2021-02-16 Varian Medical Systems, Inc. Flash therapy treatment planning and oncology information system having dose rate prescription and dose rate mapping
US11865361B2 (en) 2020-04-03 2024-01-09 Varian Medical Systems, Inc. System and method for scanning pattern optimization for flash therapy treatment planning
CN111580030B (zh) * 2020-05-13 2022-04-22 山东省肿瘤防治研究院(山东省肿瘤医院) 用于核磁共振与放疗相融合的磁场制备结构、设备及***
CN115916332A (zh) * 2020-06-17 2023-04-04 上海联影医疗科技股份有限公司 磁共振成像的***和方法
CN117599354A (zh) * 2020-06-17 2024-02-27 上海联影医疗科技股份有限公司 放射治疗设备和磁共振引导的放射治疗***
US11541252B2 (en) 2020-06-23 2023-01-03 Varian Medical Systems, Inc. Defining dose rate for pencil beam scanning
US11957934B2 (en) 2020-07-01 2024-04-16 Siemens Healthineers International Ag Methods and systems using modeling of crystalline materials for spot placement for radiation therapy
US11679281B1 (en) * 2022-06-01 2023-06-20 Accuray Incorporated Scalable slim radiotherapy treatment delivery system topology

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999032189A1 (fr) * 1997-12-19 1999-07-01 Varian Associates, Inc. Equipement de radiotherapie comportant un systeme d'imagerie par resonance magnetique
US6862469B2 (en) * 2000-01-31 2005-03-01 St. Louis University Method for combining proton beam irradiation and magnetic resonance imaging
WO2007045076A1 (fr) * 2005-10-17 2007-04-26 Alberta Cancer Board Systeme d'irm et de radiotherapie externe integre

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6198285B1 (en) * 1997-11-28 2001-03-06 Hitachi Medical Corporation In-room MRI display terminal and remote control system
IL124902A0 (en) * 1998-06-14 1999-01-26 Feldman Yosef Hydrostatic wave energy conversion system
US6879852B1 (en) * 2000-07-10 2005-04-12 Otward M. Mueller Low-cost magnetic resonance imaging (MRI) Cryo-system
US6731019B2 (en) * 2000-08-07 2004-05-04 Ocean Power Technologies, Inc. Apparatus and method for optimizing the power transfer produced by a wave energy converter (WEC)
US20040041565A1 (en) * 2002-05-08 2004-03-04 Shigeru Kakugawa NMR magnet device for solution analysis and NMR apparatus
GB2393373A (en) 2002-09-13 2004-03-24 Elekta Ab MRI in guided radiotherapy and position verification
CA2408855A1 (fr) * 2002-10-30 2004-04-30 Frank Louis Stromotich Convertisseur de l'energie des vagues oceaniques
CA2556934C (fr) 2004-02-20 2018-05-22 James F. Dempsey Systeme d'administration d'une therapie de radiation conformee pendant l'imagerie simultanee de tissu mou
US7375357B2 (en) 2004-08-23 2008-05-20 Avi Faliks Permanent magnet radiation dose delivery enhancement
US7498810B2 (en) * 2004-09-11 2009-03-03 General Electric Company Systems, methods and apparatus for specialized magnetic resonance imaging with dual-access conical bore
US7274192B2 (en) * 2005-05-31 2007-09-25 General Electric Company Combined open and closed magnet configuration for MRI
GB2427478B (en) 2005-06-22 2008-02-20 Siemens Magnet Technology Ltd Particle radiation therapy equipment and method for simultaneous application of magnetic resonance imaging and particle radiation
KR100883361B1 (ko) * 2005-12-01 2009-02-11 한국전자통신연구원 이동체 탑재형 삼중대역 안테나 시스템
US7801269B2 (en) * 2006-07-28 2010-09-21 Tomotherapy Incorporated Method and apparatus for calibrating a radiation therapy treatment system
ITRM20060418A1 (it) * 2006-08-03 2008-02-04 Tes Teleinformatica E Sistemi Srl Antenna a doppio riflettore a basso profilo a puntamento meccanico
ES2441373T3 (es) * 2006-10-11 2014-02-04 Mallinckrodt Llc Inyector de baja potencia de entrada
DE102008007245B4 (de) * 2007-02-28 2010-10-14 Siemens Aktiengesellschaft Kombiniertes Strahlentherapie- und Magnetresonanzgerät

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999032189A1 (fr) * 1997-12-19 1999-07-01 Varian Associates, Inc. Equipement de radiotherapie comportant un systeme d'imagerie par resonance magnetique
US6862469B2 (en) * 2000-01-31 2005-03-01 St. Louis University Method for combining proton beam irradiation and magnetic resonance imaging
WO2007045076A1 (fr) * 2005-10-17 2007-04-26 Alberta Cancer Board Systeme d'irm et de radiotherapie externe integre

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2009155700A1 *

Also Published As

Publication number Publication date
WO2009155700A1 (fr) 2009-12-30
EP2294312A1 (fr) 2011-03-16
WO2009155700A8 (fr) 2011-07-21
JP2011525390A (ja) 2011-09-22
CN102215912A (zh) 2011-10-12
JP5486596B2 (ja) 2014-05-07
EP2294312B1 (fr) 2016-04-27
US20110218420A1 (en) 2011-09-08
AU2009261910A1 (en) 2009-12-30
WO2009155700A9 (fr) 2011-04-21
CA2728111A1 (fr) 2009-12-30
HK1154360A1 (zh) 2012-04-20
CA2728111C (fr) 2017-09-19
AU2009261910B2 (en) 2013-10-17
US20150251020A1 (en) 2015-09-10
US8983573B2 (en) 2015-03-17
AU2009261910C1 (en) 2014-06-19
CN102215912B (zh) 2015-01-28

Similar Documents

Publication Publication Date Title
HK1154360A1 (zh) 放射治療系統
EP2240236A4 (fr) Système de thérapie cutanée
IL206654A0 (en) Combination therapy
EP2357022A4 (fr) Système de radiothérapie
EP2254612A4 (fr) Système de thérapie de plaie
EP2324789A4 (fr) Système médical
EP2448492A4 (fr) Radiothérapie guidée par image
EP2355739A4 (fr) Système de thérapie oculaire
EP2146771A4 (fr) Système de rayonnements endocavitaire
EP2346457A4 (fr) Système de thérapie de l' il
EP2346429A4 (fr) Système de thérapie oculaire
EP2412405A4 (fr) Appareil de radiothérapie
EP2537530A4 (fr) Agent de radiothérapie
EP2351526A4 (fr) Tomographie basée sur les rayons
GB2461806B (en) Electromagnetic radiation therapy
IL208351A0 (en) Antiviral therapy
EP2329772A4 (fr) Système de radiographie
GB0719518D0 (en) Therapy
GB2471750B (en) Radiation therapy device
IL201944A (en) A system for integrated energy profile treatment
EP2497534A4 (fr) Intercalaire pour thérapie par rayonnements ionisants
GB0802201D0 (en) Treatment system
GB0916997D0 (en) Combination therapy
GB0803948D0 (en) Combination therapy
GB0823273D0 (en) Treatment system

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20101214

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA RS

REG Reference to a national code

Ref document number: 602009038234

Country of ref document: DE

Ref country code: DE

Ref legal event code: R079

Free format text: PREVIOUS MAIN CLASS: F03B0013180000

Ipc: A61N0005100000

RIC1 Information provided on ipc code assigned before grant

Ipc: G01R 33/38 20060101ALI20110429BHEP

Ipc: A61B 5/055 20060101ALI20110429BHEP

Ipc: A61N 5/10 20060101AFI20110429BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20110617

RIN1 Information on inventor provided before grant (corrected)

Inventor name: FALLONE, B, GINO

Inventor name: CARLONE, MARCO

Inventor name: MURRAY, BRAD

DAX Request for extension of the european patent (deleted)
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1154360

Country of ref document: HK

17Q First examination report despatched

Effective date: 20130116

REG Reference to a national code

Ref country code: DE

Ref legal event code: R079

Ref document number: 602009038234

Country of ref document: DE

Free format text: PREVIOUS MAIN CLASS: A61N0005100000

Ipc: G01R0033480000

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

RIC1 Information provided on ipc code assigned before grant

Ipc: G01R 33/48 20060101AFI20151008BHEP

INTG Intention to grant announced

Effective date: 20151105

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 795376

Country of ref document: AT

Kind code of ref document: T

Effective date: 20160515

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602009038234

Country of ref document: DE

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 8

REG Reference to a national code

Ref country code: CH

Ref legal event code: NV

Representative=s name: SCHNEIDER FELDMANN AG PATENT- UND MARKENANWAEL, CH

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG4D

REG Reference to a national code

Ref country code: NL

Ref legal event code: MP

Effective date: 20160427

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 795376

Country of ref document: AT

Kind code of ref document: T

Effective date: 20160427

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160727

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160728

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160829

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

Ref country code: IT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602009038234

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

REG Reference to a national code

Ref country code: IE

Ref legal event code: MM4A

26N No opposition filed

Effective date: 20170130

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 9

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160625

REG Reference to a national code

Ref country code: HK

Ref legal event code: GR

Ref document number: 1154360

Country of ref document: HK

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 10

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO

Effective date: 20090625

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160625

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

Ref country code: MK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

Ref country code: MT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160630

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160427

REG Reference to a national code

Ref country code: CH

Ref legal event code: PFA

Owner name: ALBERTA HEALTH SERVICES, CA

Free format text: FORMER OWNER: ALBERTA HEALTH SERVICES, CA

REG Reference to a national code

Ref country code: DE

Ref legal event code: R082

Ref document number: 602009038234

Country of ref document: DE

Representative=s name: WSL PATENTANWAELTE PARTNERSCHAFT MBB, DE

P01 Opt-out of the competence of the unified patent court (upc) registered

Effective date: 20230529

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20230626

Year of fee payment: 15

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: CH

Payment date: 20230702

Year of fee payment: 15

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20240529

Year of fee payment: 16

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20240620

Year of fee payment: 16