EP2280779B1 - Pipette mit einem griff - Google Patents

Pipette mit einem griff Download PDF

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Publication number
EP2280779B1
EP2280779B1 EP09725898A EP09725898A EP2280779B1 EP 2280779 B1 EP2280779 B1 EP 2280779B1 EP 09725898 A EP09725898 A EP 09725898A EP 09725898 A EP09725898 A EP 09725898A EP 2280779 B1 EP2280779 B1 EP 2280779B1
Authority
EP
European Patent Office
Prior art keywords
knob
rod
piston
pipette
ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP09725898A
Other languages
English (en)
French (fr)
Other versions
EP2280779A1 (de
Inventor
Mikael Lind
Vesa Salo
Kari Järvimäki
Tapani Pullinen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thermo Fisher Scientific Oy
Original Assignee
Thermo Fisher Scientific Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thermo Fisher Scientific Oy filed Critical Thermo Fisher Scientific Oy
Publication of EP2280779A1 publication Critical patent/EP2280779A1/de
Application granted granted Critical
Publication of EP2280779B1 publication Critical patent/EP2280779B1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0224—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type having mechanical means to set stroke length, e.g. movable stops
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/08—Ergonomic or safety aspects of handling devices
    • B01L2200/087—Ergonomic aspects
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/148—Specific details about calibrations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0275—Interchangeable or disposable dispensing tips
    • B01L3/0279—Interchangeable or disposable dispensing tips co-operating with positive ejection means

Definitions

  • the invention relates to liquid dispensing and concerns a pipette, in which the volume to be dispensed is set by turning the knob of piston rod.
  • piston pipettes are used for dispensing liquids, the pipettes comprising a piston rod extending above the handle and having a knob at the end. The piston can thus be moved by the knob. Also such pipettes are used, in which the length of the piston's suction stroke, and thus the volume to be dispensed, may be set by turning the knob.
  • a pipette is known e.g. from publication FI 64752 (corresponds e.g. to EP 112887 ).
  • the dispensing volume is adjusted by turning the piston rod.
  • the dispensing volume can thus not be changed in this position.
  • the knob can however be moved from the lower position to an upper position, in which the knob turns together with the rod and the volume can thus be adjusted by turning the knob.
  • the invention provides first of all the advantage that the volume may not be changed by accident when pipetting. And when adjusting the volume, one can hold the knob easily and firmly in the way that suits best.
  • the piston rod is usually provided with some kind of a friction locking so that the rod could not turn by accident. Now the force used for the locking may be decreased, whereby a simpler and less wearing structure is achieved. Because of the smaller friction also the adjustment is easier. Also the turning knob increases the ergonomics of the pipette.
  • the structure according to the invention may be realized e.g. with indentations.
  • the rod comprises a circumferential indentation and the knob comprises a counterindentation, which, in the lower position of the knob, is located below the indentation of the rod, and, in the upper position, attached to the indentation of the rod thus preventing the turning of the knob in relation to the rod.
  • the knob must further comprise some kind of a holding mechanism, which prevents the knob from coming off the end of the rod.
  • the locking mechanism may be especially preventing by form. It may e.g. comprise flanges of different size in the knob and rod, which flanges prevent the knob from coming off.
  • the knob may comprise a locking mechanism of the upper position, which mechanism prevents the knob from transferring by itself to the lower position.
  • the transfer requires a force of at least a certain size, by which the knob has to be pressed. This increases the convenience of the volume adjustment.
  • the locking mechanisms may be realized e.g. with the help of magnets or springs.
  • a magnet mechanism may have a magnet especially in the knob. Then, even if the both mechanisms were realized, only one magnet is needed. The magnet may be especially a ring magnet.
  • Volume control may be arranged so that on the piston rod there is a thread and a nut fitted upon it, which nut has been arranged as nonrotatable in relation to the housing but as gliding in the lengthwide direction of the housing.
  • the housing has a stoppage, which together with nut determines the upper position of the piston.
  • One such pipette is known from the publication FI-64752 mentioned above. Therein the set volume is displayed by means of a series of digit wheels.
  • Figure 1 shows a pipette in accordance with the invention as a sectional view, the knob of the rod being in the lower position
  • Figures 2a and 2b show the upper end of the piston rod and the knob as an enlarged view, the knob being respectively in the lower position and in the upper position
  • Figure 3 shows the upper part of the knob from below as a perspective view
  • Figure 4 shows the lower part of the knob and the end of the rod from above as a perspective view.
  • the pipette according to Figure 1 comprises a housing 1 with a tip portion 2 at its lower end, a tip container, i.e. a tip, being fixed to the lower end of the tip portion.
  • a sliding tip ejector sleeve 3 surrounds the tip portion. It is extended by a tip ejector button 4, which, for reducing the necessary driving force, is urged to move relative to the handle by means of a wheel 5 (cf. FI 92374 corresponding e.g. to publication EP 566939 ).
  • a return spring 6 for the tip ejector is disposed on the side of the housing.
  • a handle portion 7 shaped so as to fit the user's hand is disposed on the housing.
  • the body comprises a finger support 8 at its top part.
  • the tip portion 2 is perforated with a circular hole, which continues as a hole passing through the body 1, too.
  • a piston 9 extended by a piston rod 10.
  • the lower part of the rod is sleeve-like and disposed around the upper part of the piston.
  • the upper part of the rod is narrower, extending through the housing.
  • a knob 11 is provided at the upper end of the rod.
  • the hole has an expansion, and at its bottom an O-ring 12 for sealing the piston against the tip portion.
  • the O-ring is pressed from above by an O-ring spring 13 disposed between the housing and the tip portion.
  • the piston rod 10 comprises an adjustment thread equipped with an adjustment nut 14, whose rotation relative to the body is prevented by means of longitudinal guides and grooves.
  • the body comprises a stopper 15, against which the adjustment nut and hence the piston are pressed from below by a primary spring 16.
  • the adjustment nut and the stopper determine the upper limit of the piston stroke.
  • a sleeve-like secondary support 17 has been slidingly disposed around the upper part of the rod, the secondary support having an internal flange at its lower end.
  • a calibration nut 18 is fitted with a thread into the bore of the housing, the secondary support being pressed against the calibration nut from below by means of a secondary spring 19, which has greater force than the primary spring.
  • the upper end of the rod comprises fixedly a thicker upper sleeve 20, which has been arranged to move within the calibration nut and the secondary support.
  • the sleeve has a larger diameter than the diameter of the hole formed by the lower flange of the secondary support. Together with the flange of the secondary support, the lower end of the sleeve thus determines the lower limit of the piston stroke. When liquid is aspirated into the tip, the piston is pressed against this lower limit and is then allowed to return towards the upper limit.
  • a first digit wheel 21 is fitted around the piston rod 10 so as to rotate along with this.
  • the upper end surface of the first digital ring comprises a stop notch matching each reading on the ring, the stop notch mating with a boss on a non-rotary ring spring 22 (cf. FI 92374 ).
  • the first digit wheel is connected over a first sprocket wheel 23 to a second digit wheel 24 located below, so that, after each revolution, the first digit wheel rotates the second digit wheel by one step.
  • the second digit wheel is connected with a third digit wheel 26 over a second sprocket wheel 25.
  • the upper end of the upper sleeve 20 comprises a broader cup 27 ( Fig. 2a ), the upper edge of which further comprises a broader edge flange 28.
  • the inner wall of the cup has the shape of a slightly opening cone.
  • the bottom of the cup comprises a hole in its middle.
  • the end of the piston rod 10 comprises a pin 29, which is thinner than the rod itself and which extends through the hole into the cup.
  • the outer side of the edge flange is surrounded by an indentation 30.
  • the holding ring At the lower edge of the holding ring there is a holding flange 33, the inner diameter of which is smaller than the outer diameter of the edge flange of the cup but large enough so that the holding ring is able to slide on the enlargement of the upper sleeve.
  • the cap At the lower edge of the cap, there are symmetrically four downward protrusions 34 so that the cap is able to slide on the cup.
  • the holding ring there are correspondingly four upward protrusions 35 ( Fig. 4 ), which fit the spaces between the protrusion in the cap. Outside the protrusions, there is a circumferential groove and a ring 36 fitted in it.
  • the protrusions have on the outer circumference a circumferential groove, and the ring respectively on the inner circumference a ridge fitting to the groove.
  • the indentation of the edge flange of the cup has interruptions, so that the protrusions of the holding ring can be fitted between the protrusions of the cap.
  • the upper edge of the holding indentation is wedge-shaped, so that the indentations settle comfortably interlocked, when the holding ring is lifted.
  • the knob 11 When the knob 11 is in its lower position, it rotates freely relative to the upper sleeve 20 and thus also relative to the piston rod 10, and the volume setting is consequently not changed.
  • the indentations 30 and 37 settle interlocked, whereby, when the knob is rotated, the upper sleeve and the rod rotate with, and thus the volume setting can be changed.
  • a ferromagnetic concave lower ring 38 On the bottom of the cup there is a ferromagnetic concave lower ring 38, which is attached between the edges of the cup and the pin 29.
  • the cap has in its middle a downward claw pin 39, to which a ring magnet 40 is attached.
  • a ferromagnetic upper ring 41 On the upper edge of the cup, there is further attached a ferromagnetic upper ring 41.
  • the protrusion 35 of the holding ring 32 comprises a sideways dent 42 and in the inner side of the ring 36 there is a counterindentation 43 ( Figs. 3 and 4 ). Thus the rotation of the ring has been prevented.

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Steroid Compounds (AREA)

Claims (5)

  1. Pipette, umfassend:
    - ein Gehäuse (1) mit einem Oberende und einem Unterende,
    - in dem Gehäuse einen Zylinder (2) mit einem Oberende und einem offenen Unterende,
    - in dem Zylinder einen Kolben (9) mit einer Stange an der Oberendseite des Zylinders,
    - einen Mechanismus, mit dem der Hub des Kolbens durch Drehen der Stange verändert werden kann,
    dadurch gekennzeichnet, dass
    - die Stange (10) einen Knopf (11) mit einer unteren Stellung und einer oberen Stellung relativ zu der Stange aufweist, so dass, wenn der Knopf gedreht wird, in der unteren Stellung sich die Stange mit dem Knopf nicht dreht aber in der oberen Stellung sich die Stange mit dem Knopf dreht.
  2. Pipette nach Anspruch 1, worin die Stange eine Verrastung (30) aufweist und der Knopf eine Gegenverrastung (37) aufweist, so dass in der oberen Stellung die Rasten ineinander greifen, um eine Drehung des Knopfs relativ zur Stange zu verhindern.
  3. Pipette nach Anspruch 1 oder 2, worin ein Sperrmechanismus vorgesehen ist, so dass der Knopf von der oberen Stellung zur unteren Stellung nur durch Anwendung einer ausreichend großen Kraft überführt werden kann.
  4. Pipette nach einem der Ansprüche 1 bis 3, worin ein Sperrmechanismus vorgesehen ist, so dass der Knopf von der unteren Stellung zur oberen Stellung nur durch Anwendung einer ausreichend großen Kraft überführt werden kann.
  5. Pipette nach Anspruch 3 oder 4, worin der Sperrmechanismus einen Magneten (40) aufweist.
EP09725898A 2008-03-28 2009-03-26 Pipette mit einem griff Active EP2280779B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20080247A FI120672B (fi) 2008-03-28 2008-03-28 Nupillinen pipetti
PCT/FI2009/050230 WO2009118456A1 (en) 2008-03-28 2009-03-26 Pipette with a knob

Publications (2)

Publication Number Publication Date
EP2280779A1 EP2280779A1 (de) 2011-02-09
EP2280779B1 true EP2280779B1 (de) 2012-05-09

Family

ID=39269481

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09725898A Active EP2280779B1 (de) 2008-03-28 2009-03-26 Pipette mit einem griff

Country Status (5)

Country Link
EP (1) EP2280779B1 (de)
CN (1) CN101980786B (de)
AT (1) ATE556777T1 (de)
FI (1) FI120672B (de)
WO (1) WO2009118456A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102016121816A1 (de) * 2016-11-14 2018-05-17 Ika-Werke Gmbh & Co. Kg Fluidabgabeeinheit und Handdosiervorrichtung mit wenigstens einer Fluidabgabeeinheit

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20106185A0 (fi) 2010-11-11 2010-11-11 Thermo Fisher Scientific Oy Tukipipetti
FI20106184A0 (fi) 2010-11-11 2010-11-11 Thermo Fisher Scientific Oy Kahvapipetti
FI123652B (fi) 2011-10-20 2013-08-30 Thermo Fisher Scientific Oy Lukittava pipetti
FR3037825B1 (fr) * 2015-06-24 2017-07-28 Gilson Sas Bouton de commande ameliore pour pipette de prelevement
DE102016121813A1 (de) * 2016-11-14 2018-05-17 Ika-Werke Gmbh & Co. Kg Pipette und Verfahren zum Einstellen eines zu pipettierenden Volumens einer Pipette
CN111862809B (zh) * 2020-06-30 2022-07-12 上海中航光电子有限公司 一种显示装置及车辆

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI64752C (fi) * 1982-06-29 1984-01-10 Labsystems Oy Volymreglerbar pipett
US4672857A (en) * 1985-09-10 1987-06-16 Labindustries, Inc. Liquid microdispenser
FR2696110B1 (fr) * 1992-09-28 1994-12-09 Gilson Medical Electronics Sa Perfectionnement à une piquette de prélèvement et de distribution de volumes réglables de liquides.
US5650124A (en) * 1995-07-24 1997-07-22 Gilson; Warren E. Adjustable pipette

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102016121816A1 (de) * 2016-11-14 2018-05-17 Ika-Werke Gmbh & Co. Kg Fluidabgabeeinheit und Handdosiervorrichtung mit wenigstens einer Fluidabgabeeinheit
US11207673B2 (en) 2016-11-14 2021-12-28 Ika-Werke Gmbh & Co. Kg Fluid-release unit and manual metering device with at least one fluid-release unit

Also Published As

Publication number Publication date
WO2009118456A1 (en) 2009-10-01
ATE556777T1 (de) 2012-05-15
FI20080247A (fi) 2009-09-29
FI20080247A0 (fi) 2008-03-28
FI120672B (fi) 2010-01-29
CN101980786B (zh) 2013-06-26
CN101980786A (zh) 2011-02-23
EP2280779A1 (de) 2011-02-09

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