EP2195036A4 - Compositions for treatment of tumors by direct administration of a radioisotope - Google Patents
Compositions for treatment of tumors by direct administration of a radioisotopeInfo
- Publication number
- EP2195036A4 EP2195036A4 EP08725637A EP08725637A EP2195036A4 EP 2195036 A4 EP2195036 A4 EP 2195036A4 EP 08725637 A EP08725637 A EP 08725637A EP 08725637 A EP08725637 A EP 08725637A EP 2195036 A4 EP2195036 A4 EP 2195036A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- radioisotope
- tumors
- compositions
- treatment
- direct administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/025—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus inorganic Tc complexes or compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
- A61K51/048—DTPA (diethylenetriamine tetraacetic acid)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99787307P | 2007-10-05 | 2007-10-05 | |
US99785607P | 2007-10-05 | 2007-10-05 | |
PCT/US2008/002026 WO2009045230A1 (en) | 2007-10-05 | 2008-02-15 | Compositions for treatment of tumors by direct administration of a radioisotope |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2195036A1 EP2195036A1 (en) | 2010-06-16 |
EP2195036A4 true EP2195036A4 (en) | 2011-03-09 |
Family
ID=40526495
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP08725637A Withdrawn EP2195036A4 (en) | 2007-10-05 | 2008-02-15 | Compositions for treatment of tumors by direct administration of a radioisotope |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP2195036A4 (en) |
JP (1) | JP2010540627A (en) |
CA (1) | CA2701537A1 (en) |
WO (1) | WO2009045230A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007008232A2 (en) | 2004-09-03 | 2007-01-18 | Board Of Regents, The University Of Texas System | Locoregional internal radionuclide ablation of abnormal tissues. |
DOP2010000279A (en) * | 2009-09-18 | 2012-06-15 | Sari Asher Llc | NON-SEALED NON-SEALED RADIOPHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATMENT OF ABNORMAL FABRIC |
US9437336B2 (en) | 2010-03-09 | 2016-09-06 | Kurion, Inc. | Isotope-specific separation and vitrification using ion-specific media |
GB2490317A (en) | 2011-04-19 | 2012-10-31 | Dspi Ltd | Radioactive solution undergoing in situ precipitation at a tumour site for cancer therapy |
AU2012358364B2 (en) * | 2011-12-21 | 2017-08-10 | Igl Pharma, Inc. | Radioactive compositions and methods for their therapeutic use |
WO2013191780A2 (en) | 2012-03-26 | 2013-12-27 | Kurion, Inc. | Submersible filters for use in separating radioactive isotopes from radioactive waste materials |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0313273A1 (en) * | 1987-10-14 | 1989-04-26 | Australian Nuclear Science And Technology Organisation | Macroaggregates for radiation synovectomy |
US4849209A (en) * | 1985-06-07 | 1989-07-18 | Cadema Medical Products, Inc. | Treatment of arthritis, including rheumatoid arthritis with 166 Holmium radionuclide |
WO2004050168A2 (en) * | 2002-11-27 | 2004-06-17 | Board Of Regents, The University Of Texas System | Radiopharmaceuticals and radioactive microspheres for locoregional ablation of abnormal tissues |
WO2007008232A2 (en) * | 2004-09-03 | 2007-01-18 | Board Of Regents, The University Of Texas System | Locoregional internal radionuclide ablation of abnormal tissues. |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1389090A2 (en) * | 2001-04-26 | 2004-02-18 | Board of Regents, The University of Texas System | Diagnostic imaging compositions, their methods of synthesis and use |
US8388955B2 (en) * | 2003-03-03 | 2013-03-05 | Xencor, Inc. | Fc variants |
AU2005290229A1 (en) * | 2004-09-24 | 2006-04-06 | Biosphere Medical, Inc. | Microspheres capable of binding radioisotopes, optionally comprising metallic microparticles, and methods of use thereof |
-
2008
- 2008-02-15 JP JP2010527928A patent/JP2010540627A/en active Pending
- 2008-02-15 WO PCT/US2008/002026 patent/WO2009045230A1/en active Application Filing
- 2008-02-15 CA CA2701537A patent/CA2701537A1/en not_active Abandoned
- 2008-02-15 EP EP08725637A patent/EP2195036A4/en not_active Withdrawn
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4849209A (en) * | 1985-06-07 | 1989-07-18 | Cadema Medical Products, Inc. | Treatment of arthritis, including rheumatoid arthritis with 166 Holmium radionuclide |
EP0313273A1 (en) * | 1987-10-14 | 1989-04-26 | Australian Nuclear Science And Technology Organisation | Macroaggregates for radiation synovectomy |
WO2004050168A2 (en) * | 2002-11-27 | 2004-06-17 | Board Of Regents, The University Of Texas System | Radiopharmaceuticals and radioactive microspheres for locoregional ablation of abnormal tissues |
WO2007008232A2 (en) * | 2004-09-03 | 2007-01-18 | Board Of Regents, The University Of Texas System | Locoregional internal radionuclide ablation of abnormal tissues. |
Non-Patent Citations (3)
Title |
---|
JONG D L ET AL: "Effective local control of malignant melanoma by intratumoural injection of a beta-emitting radionuclide", EUROPEAN JOURNAL OF NUCLEAR MEDICINE 2002 DE LNKD- DOI:10.1007/S00259-001-0696-Y, vol. 29, no. 2, 2002, pages 221 - 230, XP002618948, ISSN: 0340-6997 * |
MCCREADY V R ET AL: "The potential of intratumoural unsealed radioactive source therapy.", EUROPEAN JOURNAL OF NUCLEAR MEDICINE MAY 2001 LNKD- PUBMED:11383859, vol. 28, no. 5, May 2001 (2001-05-01), pages 567 - 569, XP002618949, ISSN: 0340-6997 * |
See also references of WO2009045230A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP2195036A1 (en) | 2010-06-16 |
JP2010540627A (en) | 2010-12-24 |
WO2009045230A1 (en) | 2009-04-09 |
CA2701537A1 (en) | 2009-04-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20100329 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA MK RS |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: GABRIEL INSTITUTE, INC. Owner name: ISOTHERAPEAUTICS GROUP LLC. |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20110209 |
|
17Q | First examination report despatched |
Effective date: 20120514 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20150901 |