EP2135073A4 - Methods of determining acute myeloid leukemia response to treatment with farnesyltransferase - Google Patents

Methods of determining acute myeloid leukemia response to treatment with farnesyltransferase

Info

Publication number
EP2135073A4
EP2135073A4 EP08731984A EP08731984A EP2135073A4 EP 2135073 A4 EP2135073 A4 EP 2135073A4 EP 08731984 A EP08731984 A EP 08731984A EP 08731984 A EP08731984 A EP 08731984A EP 2135073 A4 EP2135073 A4 EP 2135073A4
Authority
EP
European Patent Office
Prior art keywords
farnesyltransferase
treatment
methods
myeloid leukemia
acute myeloid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08731984A
Other languages
German (de)
French (fr)
Other versions
EP2135073A1 (en
Inventor
Mitch Raponi
Yixin Wang
Hongtao Fan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Diagnostics LLC
Original Assignee
Janssen Diagnostics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Diagnostics LLC filed Critical Janssen Diagnostics LLC
Publication of EP2135073A1 publication Critical patent/EP2135073A1/en
Publication of EP2135073A4 publication Critical patent/EP2135073A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57426—Specifically defined cancers leukemia
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B26—HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26F—PERFORATING; PUNCHING; CUTTING-OUT; STAMPING-OUT; SEVERING BY MEANS OTHER THAN CUTTING
    • B26F1/00—Perforating; Punching; Cutting-out; Stamping-out; Apparatus therefor
    • B26F1/18—Perforating by slitting, i.e. forming cuts closed at their ends without removal of material
    • B26F1/20—Perforating by slitting, i.e. forming cuts closed at their ends without removal of material with tools carried by a rotating drum or similar support
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
    • B21D—WORKING OR PROCESSING OF SHEET METAL OR METAL TUBES, RODS OR PROFILES WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
    • B21D28/00—Shaping by press-cutting; Perforating
    • B21D28/02—Punching blanks or articles with or without obtaining scrap; Notching
    • B21D28/14—Dies
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
    • B21D—WORKING OR PROCESSING OF SHEET METAL OR METAL TUBES, RODS OR PROFILES WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
    • B21D37/00—Tools as parts of machines covered by this subclass
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Mechanical Engineering (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Forests & Forestry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Shaping Metal By Deep-Drawing, Or The Like (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP08731984A 2007-03-12 2008-03-13 Methods of determining acute myeloid leukemia response to treatment with farnesyltransferase Withdrawn EP2135073A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89430807P 2007-03-12 2007-03-12
PCT/US2008/056636 WO2008112749A1 (en) 2007-03-12 2008-03-13 Methods of determining acute myeloid leukemia response to treatment with farnesyltransferase

Publications (2)

Publication Number Publication Date
EP2135073A1 EP2135073A1 (en) 2009-12-23
EP2135073A4 true EP2135073A4 (en) 2011-09-21

Family

ID=39759983

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08731984A Withdrawn EP2135073A4 (en) 2007-03-12 2008-03-13 Methods of determining acute myeloid leukemia response to treatment with farnesyltransferase

Country Status (9)

Country Link
EP (1) EP2135073A4 (en)
JP (1) JP2011512785A (en)
KR (1) KR20090113972A (en)
CN (1) CN102317772A (en)
AU (1) AU2008225130A1 (en)
BR (1) BRPI0808872A2 (en)
CA (1) CA2680909A1 (en)
MX (1) MX2009009841A (en)
WO (1) WO2008112749A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2354922B1 (en) 2009-09-02 2012-02-07 Fundacion Institut De Recerca De L'hospital Universitari Vall D'hebron MARKERS FOR THE SELECTION OF PERSONALIZED THERAPIES FOR THE TREATMENT OF THE C�? NCER.
CA3186328A1 (en) * 2010-07-28 2012-02-02 Janssen Pharmaceutica Nv Methods of determining acute myeloid leukemia response to treatment with farnesyltransferase inhibitors
US11559540B2 (en) 2010-07-28 2023-01-24 Janssen Pharmaceutica Nv Method of determining acute myeloid leukemia response to treatment with farnesyltransferase inhibitors
CN108465728A (en) * 2018-03-08 2018-08-31 佛山尘凡环保科技有限公司 A kind of high damping copper alloy material equipment
CN108500115A (en) * 2018-03-08 2018-09-07 广州拓讯安防科技有限公司 A kind of novel precise form fabrication device
CN108339880A (en) * 2018-03-08 2018-07-31 佛山尘凡环保科技有限公司 A kind of high damping copper alloy material equipment of low cost
CN108294839A (en) * 2018-03-08 2018-07-20 广州燃烧医疗技术开发有限公司 A kind of dental implant equipment of stabilization
CN108500113A (en) * 2018-03-08 2018-09-07 广州峥航机械设备有限公司 A kind of novel die design and fabrication technology equipment
CN108326118A (en) * 2018-03-08 2018-07-27 佛山尘凡环保科技有限公司 A kind of Novel high-damping copper alloy material equipment
CN108500114A (en) * 2018-03-08 2018-09-07 广州峥航机械设备有限公司 A kind of efficiently advanced mold design and manufacturing technology equipment
CN108481435A (en) * 2018-03-08 2018-09-04 广州拓讯安防科技有限公司 A kind of precision form manufacturing device
CN108453165A (en) * 2018-03-08 2018-08-28 广州峥航机械设备有限公司 A kind of advanced mold design and manufacturing technology equipment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0206251A (en) * 2001-10-30 2004-06-15 Ortho Clinical Diagnostics Inc Methods to Evaluate and Treat Leukemia
US20050003422A1 (en) * 2003-07-01 2005-01-06 Mitch Reponi Methods for assessing and treating cancer

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
M. RAPONI ET AL: "A 2-gene classifier for predicting response to the farnesyltransferase inhibitor tipifarnib in acute myeloid leukemia", BLOOD, vol. 111, no. 5, 1 March 2008 (2008-03-01), pages 2589 - 2596, XP055004522, ISSN: 0006-4971, DOI: 10.1182/blood-2007-09-112730 *
See also references of WO2008112749A1 *

Also Published As

Publication number Publication date
AU2008225130A1 (en) 2008-09-18
CA2680909A1 (en) 2008-09-18
KR20090113972A (en) 2009-11-03
WO2008112749A1 (en) 2008-09-18
BRPI0808872A2 (en) 2014-11-11
EP2135073A1 (en) 2009-12-23
JP2011512785A (en) 2011-04-28
MX2009009841A (en) 2009-09-24
CN102317772A (en) 2012-01-11

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Inventor name: WANG, YIXIN

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