EP2126118A4 - Method and kit for detection of mbcr/abl gene fusion and c-kit (cd117) - Google Patents

Method and kit for detection of mbcr/abl gene fusion and c-kit (cd117)

Info

Publication number
EP2126118A4
EP2126118A4 EP08713271A EP08713271A EP2126118A4 EP 2126118 A4 EP2126118 A4 EP 2126118A4 EP 08713271 A EP08713271 A EP 08713271A EP 08713271 A EP08713271 A EP 08713271A EP 2126118 A4 EP2126118 A4 EP 2126118A4
Authority
EP
European Patent Office
Prior art keywords
kit
mbcr
detection
gene fusion
abl gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08713271A
Other languages
German (de)
French (fr)
Other versions
EP2126118A2 (en
Inventor
Patrick J Muraca
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nuclea Biomarkers LLC
Original Assignee
Nuclea Biomarkers LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuclea Biomarkers LLC filed Critical Nuclea Biomarkers LLC
Publication of EP2126118A2 publication Critical patent/EP2126118A2/en
Publication of EP2126118A4 publication Critical patent/EP2126118A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP08713271A 2007-01-24 2008-01-24 Method and kit for detection of mbcr/abl gene fusion and c-kit (cd117) Withdrawn EP2126118A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89716107P 2007-01-24 2007-01-24
PCT/US2008/000958 WO2008091679A2 (en) 2007-01-24 2008-01-24 Method and kit for detection of mbcr/abl gene fusion and c-kit (cd117)

Publications (2)

Publication Number Publication Date
EP2126118A2 EP2126118A2 (en) 2009-12-02
EP2126118A4 true EP2126118A4 (en) 2010-09-01

Family

ID=39645079

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08713271A Withdrawn EP2126118A4 (en) 2007-01-24 2008-01-24 Method and kit for detection of mbcr/abl gene fusion and c-kit (cd117)

Country Status (2)

Country Link
EP (1) EP2126118A4 (en)
WO (1) WO2008091679A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002093130A2 (en) * 2001-05-14 2002-11-21 Cancer Genetics, Inc. Methods of analyzing chromosomal translocations using fluorescence in situ hybridization (fish)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030017491A1 (en) * 2000-09-14 2003-01-23 Zuo-Rong Shi Chromogenic in situ hybridization methods, kits, and compositions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002093130A2 (en) * 2001-05-14 2002-11-21 Cancer Genetics, Inc. Methods of analyzing chromosomal translocations using fluorescence in situ hybridization (fish)

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KATO I ET AL: "Composition for suppressing human Flt-3 function", EMBL,, 21 April 2005 (2005-04-21), XP007914038 *
KATO I ET AL: "Composition for suppressing human Flt-3 function", EMBL,, 21 April 2005 (2005-04-21), XP007914039 *

Also Published As

Publication number Publication date
EP2126118A2 (en) 2009-12-02
WO2008091679A2 (en) 2008-07-31
WO2008091679A3 (en) 2008-12-24

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20090723

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DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20100804

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18W Application withdrawn

Effective date: 20111028