EP2052749A3 - Polymethylmethacrylat-Knochenzement - Google Patents

Polymethylmethacrylat-Knochenzement Download PDF

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Publication number
EP2052749A3
EP2052749A3 EP08016945A EP08016945A EP2052749A3 EP 2052749 A3 EP2052749 A3 EP 2052749A3 EP 08016945 A EP08016945 A EP 08016945A EP 08016945 A EP08016945 A EP 08016945A EP 2052749 A3 EP2052749 A3 EP 2052749A3
Authority
EP
European Patent Office
Prior art keywords
bone cement
alkyl
total joint
pmma bone
joint endoprostheses
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08016945A
Other languages
English (en)
French (fr)
Other versions
EP2052749A2 (de
Inventor
Sebastian Dr. Vogt
Hubert Dr. Büchner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heraeus Medical GmbH
Original Assignee
Heraeus Medical GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heraeus Medical GmbH filed Critical Heraeus Medical GmbH
Publication of EP2052749A2 publication Critical patent/EP2052749A2/de
Publication of EP2052749A3 publication Critical patent/EP2052749A3/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043—Mixtures of macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

Es wird ein PMMA-Knochenzement beschrieben, enthaltend
mindestens ein Homopolymer oder ein Copolymer, das eine Glasübergangstemperatur von größer 45 °C besitzt, und
mindestens ein biokompatibles Elastomer mit einer Glastemperatur kleiner 37 °C, das in Alkylmethacrylaten und/oder Alkyldimethacrylaten und/oder Alkyltrimethacrylaten und/oder Alkyltetramethacrylaten löslich oder unlöslich ist und einen Restmonomergehalt von kleiner 5 Prozent besitzt. Der PMMA-Knochenzement wird vorzugsweise als selbsthärtender Kunststoff zur Fixierung von primären Totalgelenkendoprothesen und von Revisions-Totalgelenkendoprothesen verwendet. Weiterhin kann der PMMA-Knochenzement Verwendung als selbsthärtendes Füllmaterial für die Vertebroplastie, die Kyphoplastie und die Femurhals-Augmentation sowie für die Herstellung von temporären Platzhaltern für zweizeitige Revisionen von Totalgelenkendoprothesen finden.
EP08016945A 2007-10-22 2008-09-26 Polymethylmethacrylat-Knochenzement Withdrawn EP2052749A3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102007050768A DE102007050768A1 (de) 2007-10-22 2007-10-22 Polymethylmethacrylat-Knochenzement

Publications (2)

Publication Number Publication Date
EP2052749A2 EP2052749A2 (de) 2009-04-29
EP2052749A3 true EP2052749A3 (de) 2009-07-15

Family

ID=40293630

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08016945A Withdrawn EP2052749A3 (de) 2007-10-22 2008-09-26 Polymethylmethacrylat-Knochenzement

Country Status (5)

Country Link
US (1) US20090105369A1 (de)
EP (1) EP2052749A3 (de)
JP (1) JP2009101161A (de)
AU (1) AU2008229939A1 (de)
DE (1) DE102007050768A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007050762B3 (de) * 2007-10-22 2009-05-07 Heraeus Medical Gmbh Pastenförmiger Polymethylmethacrylat-Knochenzement und seine Verwendung
EP3106146A1 (de) * 2015-06-15 2016-12-21 Dentsply DeTrey GmbH Wässrige dentale glasionomerzusammensetzung
DE102015217315A1 (de) * 2015-09-10 2017-03-16 Heraeus Medical Gmbh Polymethylmethacrylat-Knochenzement mit einstellbarer initialer Viskosität und ein Verfahren zur Herstellung eines Knochenzementteigs mit variabler initialer Viskosität
EP3231412A3 (de) * 2016-04-15 2017-10-25 DENTSPLY DETREY GmbH Wässrige dentale glasionomerzusammensetzung
EP3338757A1 (de) * 2016-12-20 2018-06-27 Dentsply DeTrey GmbH Direkte zahnfüllungszusammensetzung
CN108096629B (zh) * 2018-01-29 2021-08-06 奥精医疗科技股份有限公司 一种聚甲基丙烯酸甲酯骨粘固剂及其制备方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4404327A (en) * 1979-10-31 1983-09-13 Crugnola Aldo M Orthopaedic cement from acrylate polymers
US4863977A (en) * 1983-11-16 1989-09-05 Dentsply Research & Development Corp. Process for preparing interpenetrating polymer network objects employing rubber-modified polymers
US5242983A (en) * 1992-03-19 1993-09-07 Edison Polymer Innovation Corporation Polyisobutylene toughened poly(methyl methacrylate)
US20040226479A1 (en) * 1995-02-08 2004-11-18 M.E.D. Usa, Inc. Bone cement compositions comprising fused fibrous compounds
EP1520562A2 (de) * 2003-10-01 2005-04-06 Biomet Deutschland GmbH Vorrichtung zum Mischen und Austragen von flüssigen und pulverförmigen Materialien für die medizinische Verwendung
US20070048382A1 (en) * 2005-08-29 2007-03-01 Jorg Meyer Bone cement composition and method of making the same

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4550449A (en) * 1982-11-08 1985-11-05 Johnson & Johnson Products Inc. Absorbable bone fixation device
US4551486A (en) * 1983-11-16 1985-11-05 Dentsply Research & Development Corp. Interpenetrating polymer network compositions
EP0434334B1 (de) * 1989-12-21 1994-02-02 Minnesota Mining And Manufacturing Company Zahnärztliche Zusammensetzungen, Verfahren zur Herstellung von geformten, zahnärztlichen Artikeln via "photoiniferte Polymerisation" von zahnärztlichen Zusammensetzungen und dadurch erzeugte geformte, zahnärztliche Artikel
US5154762A (en) * 1991-05-31 1992-10-13 Minnesota Mining And Manufacturing Company Universal water-based medical and dental cement
US6103779A (en) * 1995-04-26 2000-08-15 Reinforced Polmers, Inc. Method of preparing molding compositions with fiber reinforcement and products obtained therefrom
JP4086338B2 (ja) * 1996-12-06 2008-05-14 株式会社松風 歯科用弾性修復材料並びにそれを用いた歯科補綴材料の作製方法
US5914356A (en) * 1996-12-06 1999-06-22 Orthovita, Inc. Bioactive load bearing bone bonding compositions
CA2233150A1 (en) * 1997-03-31 1998-09-30 Kuraray Co., Ltd. Resinous composition for dental use
JP4419112B2 (ja) * 2000-03-22 2010-02-24 株式会社ビーエムジー 強靭な義歯床および製造法
EP1367960B1 (de) * 2001-01-26 2005-11-02 UAB Research Foundation Knochenzement
JP4653657B2 (ja) * 2003-05-23 2011-03-16 三井化学株式会社 （メタ）アクリル酸エステル化合物およびその用途
US20050124762A1 (en) * 2003-12-03 2005-06-09 Cohen Gordon M. Dental compositions containing core-shell polymers with low modulus cores
EP1850797B1 (de) * 2005-02-22 2014-04-30 Depuy Spine, Inc. Knochenzement

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4404327A (en) * 1979-10-31 1983-09-13 Crugnola Aldo M Orthopaedic cement from acrylate polymers
US4863977A (en) * 1983-11-16 1989-09-05 Dentsply Research & Development Corp. Process for preparing interpenetrating polymer network objects employing rubber-modified polymers
US5242983A (en) * 1992-03-19 1993-09-07 Edison Polymer Innovation Corporation Polyisobutylene toughened poly(methyl methacrylate)
US20040226479A1 (en) * 1995-02-08 2004-11-18 M.E.D. Usa, Inc. Bone cement compositions comprising fused fibrous compounds
EP1520562A2 (de) * 2003-10-01 2005-04-06 Biomet Deutschland GmbH Vorrichtung zum Mischen und Austragen von flüssigen und pulverförmigen Materialien für die medizinische Verwendung
US20070048382A1 (en) * 2005-08-29 2007-03-01 Jorg Meyer Bone cement composition and method of making the same

Also Published As

Publication number Publication date
AU2008229939A1 (en) 2009-05-07
DE102007050768A1 (de) 2009-04-23
EP2052749A2 (de) 2009-04-29
US20090105369A1 (en) 2009-04-23
JP2009101161A (ja) 2009-05-14

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