EP1945208A4 - Composition and synthesis of new reagents for inhibition of hiv replication - Google Patents
Composition and synthesis of new reagents for inhibition of hiv replicationInfo
- Publication number
- EP1945208A4 EP1945208A4 EP06825592A EP06825592A EP1945208A4 EP 1945208 A4 EP1945208 A4 EP 1945208A4 EP 06825592 A EP06825592 A EP 06825592A EP 06825592 A EP06825592 A EP 06825592A EP 1945208 A4 EP1945208 A4 EP 1945208A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- inhibition
- synthesis
- composition
- hiv replication
- new reagents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
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- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
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- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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CN111548313A (en) * | 2019-02-11 | 2020-08-18 | 绍兴从零医药科技有限公司 | Guanidine compounds as medicine for preventing and treating chronic pain |
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WO2004085419A1 (en) * | 2003-03-24 | 2004-10-07 | Basf Aktiengesellschaft | Trifluoromethyl-thiophene carboxylic acid anilides and use thereof as fungicides |
US20050049242A1 (en) * | 2000-12-21 | 2005-03-03 | W. Edward Robinson | Novel HIV integrase inhibitors and HIV therapy based on drug combinations including integrase inhibitors |
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IL141028A0 (en) * | 1998-07-28 | 2002-02-10 | Smithkline Beecham Corp | Substituted anilide compounds and methods |
CA2362401A1 (en) * | 1999-02-04 | 2000-08-10 | Paul Fleming | G-protein coupled heptahelical receptor binding compounds and methods of use thereof |
US20050123906A1 (en) | 2003-11-06 | 2005-06-09 | Rana Tariq M. | Protein modulation |
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2006
- 2006-10-06 US US11/544,068 patent/US7754773B2/en active Active
- 2006-10-06 EA EA200801025A patent/EA200801025A1/en unknown
- 2006-10-06 KR KR1020087010911A patent/KR20080059634A/en not_active Application Discontinuation
- 2006-10-06 EP EP06825592A patent/EP1945208A4/en not_active Withdrawn
- 2006-10-06 AP AP2008004459A patent/AP2008004459A0/en unknown
- 2006-10-06 WO PCT/US2006/039228 patent/WO2007044565A2/en active Application Filing
- 2006-10-06 CA CA002628863A patent/CA2628863A1/en not_active Abandoned
- 2006-10-06 CN CNA2006800462146A patent/CN101355939A/en active Pending
-
2008
- 2008-05-06 ZA ZA2008/03862A patent/ZA200803862B/en unknown
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US3532702A (en) * | 1966-04-15 | 1970-10-06 | American Cyanamid Co | 2-(o-aminophenoxy or phenylthio) phenyl-1-substituted (piperidyl or pyrrolidinyl) ketones |
DE2126149A1 (en) * | 1971-05-26 | 1972-12-07 | Farbenfabriken Bayer Ag, 5090 Leverkusen | Halo-salicylanilide derivs - with acaricidal and fungicidal activity |
US4356325A (en) * | 1980-11-28 | 1982-10-26 | Gulf Research & Development Company | Process for preparation of acetylene terminated sulfones, oligomers and precursors therefor |
WO2000009482A1 (en) * | 1998-08-12 | 2000-02-24 | Syngenta Participations Ag | Trifluoro methylpyrrol carboxamides |
WO2000027825A1 (en) * | 1998-11-10 | 2000-05-18 | Janssen Pharmaceutica N.V. | Hiv replication inhibiting pyrimidines |
US20050049242A1 (en) * | 2000-12-21 | 2005-03-03 | W. Edward Robinson | Novel HIV integrase inhibitors and HIV therapy based on drug combinations including integrase inhibitors |
WO2002078708A1 (en) * | 2001-03-15 | 2002-10-10 | Janssen Pharmaceutica N.V. | Hiv inhibiting pyrazinone derivatives |
WO2004085419A1 (en) * | 2003-03-24 | 2004-10-07 | Basf Aktiengesellschaft | Trifluoromethyl-thiophene carboxylic acid anilides and use thereof as fungicides |
Also Published As
Publication number | Publication date |
---|---|
CN101355939A (en) | 2009-01-28 |
WO2007044565A3 (en) | 2007-06-07 |
WO2007044565A2 (en) | 2007-04-19 |
KR20080059634A (en) | 2008-06-30 |
ZA200803862B (en) | 2014-10-29 |
US7754773B2 (en) | 2010-07-13 |
US20070099919A1 (en) | 2007-05-03 |
AP2008004459A0 (en) | 2008-06-30 |
EA200801025A1 (en) | 2008-12-30 |
CA2628863A1 (en) | 2007-04-19 |
EP1945208A2 (en) | 2008-07-23 |
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