EP1879533A2 - Prothese pour la restauration de mouvement - Google Patents
Prothese pour la restauration de mouvementInfo
- Publication number
- EP1879533A2 EP1879533A2 EP06769925A EP06769925A EP1879533A2 EP 1879533 A2 EP1879533 A2 EP 1879533A2 EP 06769925 A EP06769925 A EP 06769925A EP 06769925 A EP06769925 A EP 06769925A EP 1879533 A2 EP1879533 A2 EP 1879533A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- bone
- flexural modulus
- prosthesis
- gpa
- motion restoring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/442—Intervertebral or spinal discs, e.g. resilient
- A61F2/4425—Intervertebral or spinal discs, e.g. resilient made of articulated components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/32—Joints for the hip
- A61F2/34—Acetabular cups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
- A61F2/4465—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages having a circular or kidney shaped cross-section substantially perpendicular to the axis of the spine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/32—Phosphorus-containing materials, e.g. apatite
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/14—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor incorporating preformed parts or layers, e.g. injection moulding around inserts or for coating articles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30965—Reinforcing the prosthesis by embedding particles or fibres during moulding or dipping
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/32—Joints for the hip
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/32—Joints for the hip
- A61F2/36—Femoral heads ; Femoral endoprostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/32—Joints for the hip
- A61F2/36—Femoral heads ; Femoral endoprostheses
- A61F2/3662—Femoral shafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
- A61F2002/30014—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis differing in elasticity, stiffness or compressibility
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
- A61F2002/30016—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis differing in hardness, e.g. Vickers, Shore, Brinell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/3011—Cross-sections or two-dimensional shapes
- A61F2002/30112—Rounded shapes, e.g. with rounded corners
- A61F2002/30113—Rounded shapes, e.g. with rounded corners circular
- A61F2002/30118—Rounded shapes, e.g. with rounded corners circular concentric circles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/3011—Cross-sections or two-dimensional shapes
- A61F2002/30112—Rounded shapes, e.g. with rounded corners
- A61F2002/30133—Rounded shapes, e.g. with rounded corners kidney-shaped or bean-shaped
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30593—Special structural features of bone or joint prostheses not otherwise provided for hollow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30621—Features concerning the anatomical functioning or articulation of the prosthetic joint
- A61F2002/30649—Ball-and-socket joints
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30621—Features concerning the anatomical functioning or articulation of the prosthetic joint
- A61F2002/30649—Ball-and-socket joints
- A61F2002/3065—Details of the ball-shaped head
-
- A—HUMAN NECESSITIES
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30621—Features concerning the anatomical functioning or articulation of the prosthetic joint
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- A61F2002/30654—Details of the concave socket
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
- A61F2002/30682—Means for preventing migration of particles released by the joint, e.g. wear debris or cement particles
- A61F2002/30685—Means for reducing or preventing the generation of wear particulates
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30772—Apertures or holes, e.g. of circular cross section
- A61F2002/30784—Plurality of holes
- A61F2002/30787—Plurality of holes inclined obliquely with respect to each other
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/3082—Grooves
- A61F2002/30822—Circumferential grooves
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2071/00—Use of polyethers, e.g. PEEK, i.e. polyether-etherketone or PEK, i.e. polyetherketone or derivatives thereof, as moulding material
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- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/753—Medical equipment; Accessories therefor
- B29L2031/7532—Artificial members, protheses
Definitions
- This application relates to (a) motion restoring prosthesis for placement between the ends of two bones adjoining a mammalian appendage or spinal joint, such as an artificial intervertebral disc or hip/knee/shoulder joint and (b) intervertebral spacer for accommodating fusion between the separated vertebrae.
- German Patent No. 2,263,842 With respect to motion restoring intervertebral devices see German Patent No. 2,263,842 and the devices disclosed therein. These include ball and socket prostheses with single and/or dual articulations and with and without motion dampening elements.
- U.S. Patent No. 5,899,941 discloses a similar device, but where the articulating surface is generally non-conforming to allow rotation and translational movement. This is similar to the device illustrated in U.S. Patent No. 6,113,637 by Gill et al. This artificial spinal disc incorporates a ball and trough type articulation with a substantially flat portion. Both the Yuichiro and Gill et al. patents describe devices which rely on point contact, a potential source of excessive wear debris. Also, see the prior art discussed in the '701 patent and U.S. Patent No. 5,071 ,437 ('"437 patent").
- a hard/stiff material generally ceramic or a cobalt chromium alloy
- abutting the faces of the separated vertebrae results in stress shielding, i.e., a nonuniform distribution of the forces transmitted from the articulating surfaces to the abutted vertebrae bone faces.
- This nonuniform loading can result in so called hard spots on the bone face where the load is being transmitted and soft spots where little or no load is being transmitted, with the consequence that the soft spots tend to result in bone absorption, thereby loosening the implant and causing eventual failure.
- Hip joints typically include a metal cup which houses the acetabular bearing portion, which metal cup is secured, via cement, for example, directly to the bone. See, for example, U.S. Patent Nos. 6,368,354 ("'354 patent") and 6,966,932 ("932 patent").
- the metal to bone contact provides a nonuniform stress loading to the exposed bone face with a significant potential of causing the implant to loosen from the underlying implant.
- both of the above patents illustrate an interlocking arrangement between several sections of the acetabular component.
- the interface between the outer metal shell and the bone end or face forming the acetabulum does not resolve the nonuniform loading on the bone face.
- a spacer or disc replacement member made of a material such as Ti 3 has been used to maintain the vertebrae encompassing a failed natural disc in a separated condition during the fusion process.
- spacers formed of a softer material, such as PEEK have been used for this purpose to provide better stress transfer to the bone during the fusion process.
- PEEK is not particularly bone attachment friendly. There is a need to provide an artificial disc replacement member which accommodates both even stress transfer and bone-on growth attachment.
- a motion restoring prosthesis adapted to be placed between the ends of two bones adjoining a mammalian appendage or spinal joint, in accordance with the present invention, includes two components with each component defining an outer surface for attachment to a respective bone end and an articulating surface for engaging the articulating surface of the other component. At least one of the components has an inner and outer section.
- the inner section, defining the articulating surface is made of a primary relatively hard/stiff material such as ceramic, cobalt chromium, or other hard, stiff bio-compatible material for inhibiting the wear between the articulating surfaces.
- the outer section is made of a secondary material (sometimes hereinafter referred to as the "bone buttressing material”) that is softer and less stiff than the primary material (sometimes referred to as the "articulating material”).
- the secondary material is formed of a biocompatible polymer having a hardness/stiffness characteristic closer to that of the bone to be buttressed.
- Polyetheretherketone (“PEEK”) or carbon fiber reinforced PEEK (“CFRPEEK”) are clear choices. These polymers reduce stress shielding by more evenly distributing the forces or load from the articulating surfaces to the respective bone interface end thereby enhance the life of the prosthesis.
- the flexural moduli of the primary and secondary materials are, respectfully, within the range of about 80+ and about 60 or less on the Giga Pascal Scale (GPa), which scale provides a measure of elasticity versus pressure.
- GPa Giga Pascal Scale
- the secondary material has a GPa range of about 4 to 30 or about 12-25 while cortical bone has a GPa of about 17 ⁇ 5-8.
- the bone buttressing surface of each of the outer sections are roughened and/or made uneven to enhance the attachment of bone thereto.
- the bone buttressing surface prefferably has a very thin coating or layer of a bone-on growth attachment friendly material, such as titanium, calcium phosphate or hydroxyapatite thereon, which does not materially increase the stiffness of the bone buttressing surface of the secondary material to detract from the stress shielding characteristic thereof, while enhancing the attachment of the bone thereto.
- a bone-on growth attachment friendly material such as titanium, calcium phosphate or hydroxyapatite thereon
- the thin coating of such material is within the range of about 0.5 to 15.0 or more microns and most preferably within the range of about 0.50 to 3.0 microns.
- both components are formed with inner and outer sections.
- the inner sections are formed of the primary material and preferably define a ball and socket type articulating surface as described in the '744 application.
- the outer sections are formed of the softer secondary material which define the bone buttressing surfaces for attachment to the respective bone faces of the separated vertebral bodies.
- the softer outer sections partially encapsulate the inner sections, e.g., by an injection molding process, to substantially prevent any motion including macromotion between the inner and outer sections.
- an artificial intervertebral disc or spacer for accommodating fusion, is preferably formed of a material such as PEEK or CRFPEEK having a flexure modulus comparable to that of cortical bone.
- the spacer is provided with a roughened and/or uneven surface and subsequently provided with a very thin coating of a material such as Ti which enhances bone-on growth without adversely affecting the bone friendly surface characteristic of the PEEK or CFRPEEK as discussed above.
- Fig. 1 is a side elevational view of a motion restoring prosthesis for replacing a natural spinal disc in accordance with the present invention
- Fig. 2 is a cross-sectional view of the prosthesis of Fig. 1 taken along lines 2-2 of Fig. 1;
- Fig. 3 is a cross-sectional view of the prosthesis of fig. 1 taken along lines 3-3 of Fig. 2;
- Figs. 4 and 5 are perspective and cross-sectional views, respectfully, of a slightly modified artificial spinal disc in which the bone buttressing surface of the secondary material are coated with a coating of bone-on growth attachment friendly material;
- Fig. 6 is a cross-sectional view taken along lines 6-6 of Fig. 5;
- Fig. 7 is a simple diagrammatic view of a hip joint prosthesis illustrating a dual section acetabular component in accordance with this invention;
- Figs. 8, 9, and 10 are simple diagrammatic views showing the several parts which make up the prosthesis of Fig. 7 in a partially unassembled and assembled condition;
- Fig. 11 is a diagrammatic view of the femoral component inserted in the femoral bone
- Figs. 12, 13, and 14 are perspective, front and rear elevational views, respectively, of an acetabular component of the hip joint prosthesis of Fig. 7;
- Fig. 15 is a cross-sectional view of the acetabular component of figs. 11-13 showing the inner and outer cup sections;
- Figs. 16 and 17 are cross-sectional and perspective views of an acetabular cup showing an outside uneven and roughened surface with a thin layer of coating of a bone-on growth friendly attachment material thereon;
- Fig. 18 is a side elevational view of the acetabular component of Fig. 15 and;
- Fig. 19 is a cross-sectional view of a mold suitable for partially encapsulating the primary (articulating) material with the softer secondary (bone buttressing material) for one of the components of a motion restoring vertebral prosthesis of Figs. 1 -6.
- Fig. 20 is a perspective view of an artificial intervertebral spacer formed of a material, e.g., PEEK, and coated with a bone-on growth friendly material, e.g., Ti, for accommodating relatively uniform stress transfer to the vertebral bone faces while promoting bone-on growth attachment.
- a material e.g., PEEK
- a bone-on growth friendly material e.g., Ti
- a motion restoring intervertebral prosthesis in accordance with this invention, comprises first and second components 10 and 12 with the components having inner sections 10a and 12a (formed of a primary material) and outer sections 10b and 12b (formed of a secondary material), respectively.
- the sections are integrally formed, preferably by an injection molding process, so that the secondary material partially encloses or encapsulates the primary material (except for the articulating surfaces) as will be explained with respect to Fig. 17.
- outwardly extending protrusions 10c and 12c of the primary material are overlapped by an inwardly extending shoulders 1Od and 12d of the secondary material.
- the inner sections 10a and 12a define cooperating articulating surfaces 1Oe and 12e in the form of a ball and modified socket to provide controlled rotation in the frontal plane and controlled rotation with translation in the sagittal plane as is described in some detail in the
- top outer surfaces 1Of and 12f form the bone (vertebral) buttressing surfaces.
- the primary material is formed from a relatively hard, stiff material, such ceramic or a cobalt chromium alloy, to minimize the wear between the articulating surfaces and increase the life expectancy of the prosthesis.
- the secondary or bone buttressing material is softer and less stiff than the primary material to accommodate surface irregularities in the underlying vertebral bone faces and more evenly distribute the forces or load from the articulating surfaces to the respective bone faces thereby inhibiting the formation of the hot and cold spots. In this manner it is believed that the softer secondary material serves to dampen the stresses imparted to the bone faces and increase the life expectancy of the prosthesis.
- the secondary material should have a flexural modulus on the GPa scale of about 60 or less and preferably within the range of 4 to 30 and most preferably about 17 ⁇ 5-8 which is the flexural modulus spectrum of cortical bone.
- the primary material may be made of a biocompatible ceramic, e.g., alumina ceramic, which has a GPa flexural modulus of about 158 ⁇ 10% while another suitable primary materials is cobalt chromium alloy (including some molybdenum) which has GPa flexural modulus of about 80.
- PEEK is an excellent implantable bio-compatible material suitable for use as the secondary material with a GPa flexural modulus of about 4 and when reinforced with 20% carbon fiber has a GPa of about 18.
- the carbon fiber content may be adjusted from 0 to about 80%, but we have found that a mixture of about 30 to 35% of carbon fiber by weight provides a preferred bone-to-implant surface while providing sufficient support for the molded insert of articulating (primary) material and it has a stiffness slightly higher than the average (i.e., about 17 GPa) for cortical bone, but less than 30 GPa, i.e, about 21-24, while being imaging friendly, i.e., translucent to the conventional imaging processes.
- Protrusions 14, commonly referred to as keels may be in the form of headed rods or bolts for enhancing the attachment of the prosthesis to the underlying bone.
- the heads 14a of the rods are preferably embedded in the inner sections as shown.
- Figs. 4, 5, and 6 illustrate a slightly different design of a motion restoring vertebral prosthesis, with primed numerals being used to refer to corresponding components and portions of the prosthesis of Figs. 1-3.
- the outer surfaces of the second components, formed of the secondary material are coated with a very thin layer 16 of a material which promotes the affixation of bone to the bone buttressing surfaces while essentially maintaining the ability of such surfaces to accommodate surface irregularities of the bone face and provide stress softening.
- a very thin coating of Ti, calcium phosphate or hydroxyapatite serves this purpose.
- Such coating or layer can be applied by a conventional vacuum/electronic ionic fusion processes.
- such a coating should have a thickness within the range of about 0.5 to 15.0 microns and most preferably between about 0.5 to 3.0 microns. It should be noted that such a coating on a prosthesis component made of the described secondary material forming a bone buttressing surface may be useful independently of the material forming the articulating surface.
- FIG. 8-16 A hip joint prosthesis is illustrated in Figs. 8-16. With this type of prosthesis it is feasible, as a general rule, to form only the acetabular component 18 with a relatively soft outer secondary bone buttressing material, such as PEEK or CFRPEEK, secured over the harder and stiffer inner primary articulating material such as ceramic.
- a femoral component 22 comprises a conventional rod 22a inserted into the patient's femur 24 with the end of the rod carrying a conventional ball 22b of primary material positioned on a shaft 22c.
- Figs. 8-11 illustrate the components in an unassembled and partially assembled form.
- the present invention concerns the structure of the acetabular component 18, which, as is illustrated in Figs. 12-15, comprises an inner section 18a and an outer section 18b.
- Section 18a like section 1 Oa of the first component of the device of Figs. 1-3, is formed of a relatively hard/stiff material such as ceramic to form an inner semi-spherical articulating surface 18c for cooperating with the femoral ball 22b.
- the inner section 18a is mounted within the outer section 18b, preferably via an injection molding process in which tongues and grooves 18d are preferably formed in the outer surface of the first component prior to the molding step to mechanically lock the first and second components together.
- the outer or bone buttressing surface 18e of the second semi-spherical section 18b is preferably formed in the mold with (circular) grooves 18f (forming an uneven surface) to aid in locking the bone buttressing surface to the bone.
- the bone buttressing surface may be roughened by blasting the surface with an appropriate abrasive resorbable media, such as kieserite after the molding step to provide a roughened surface 18g, as is illustrated in Figs. 17 and 18.
- This roughened and/or uneven surface is then preferably provided with a thin micron layer 18h bone-on growth attachment enhancing material such as Ti. See Fig. 18.
- Fig. 19 illustrates a simple two part injection mold comprising parts 26 and 28 with a first or articulating surface forming section 30 (illustrated as ceramic) placed therein.
- the secondary material e.g., polymer, such as PEEK or CFRPEEK, is forced in duct 32 while air escapes through duct 34.
- the result is a finished or semi-finished component with the secondary material partially encapsulating the primary material.
- the upper exposed (and perhaps all of the) surface of the upper section may then be roughened and coated with a thin micron layer of Ti, etc. as desired.
- Fig. 20 illustrates a artificial intervertebral spacer 36 for placement in the space between adjacent vertebral bodies which has been vacated by a failed natural disc.
- the spacer is made of a relatively soft material, e.g., PEEK or CFRPEEK, having a flexural modulus similar to that of the bone forming the vertebral bodies to be fused.
- the GPa flexural modulus of the soft material preferably is within the range of about 4-30 and most preferably about 17 ⁇ 8.
- the top bone buttressing surface 36 is formed with serrated edges or teeth 36b (i.e., providing an uneven surface).
- the spacer is roughened by an apparent blast media or tumbled in an abrasive media to create a micro surface roughening.
- the spacer is then coated with a thin micron layer (i.e., 0.5 to 3-10 microns) of a material e.g., Ti, calcium phosphate or hydroxyaptite, which will promote bone-on growth without materially modifying the stress transfer characteristic between the soft material and the bone.
- a thin micron layer i.e., 0.5 to 3-10 microns
- Ti titanium, calcium phosphate or hydroxyaptite
- the spacer is formed with holes 36d in the side walls and open central portion 36e as shown.
- the bottom bone buttressing surface (not shown) will be similar or identical to the top surface.
- a novel prosthesis for restoring motion in an appendage or spinal joint which employs a relatively hard-stiff material to form the articulating surfaces while employing a softer less stiff material to form one or both bone buttressing surfaces to inhibit wear at the articulating surfaces while reducing stress shielding at the prosthesis bone interface(s).
- the softer material is provided with a thin micron coating of a material which promotes bone attachment without adversely affecting the reduction in stress shield.
- a novel intervertebral spacer member having the flexural modulus comparable to that of the separated vertebrae while promoting bone attachment to the spacer member.
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Prostheses (AREA)
Abstract
L'invention concerne une prothèse de restauration de mouvement destinée à être intercalée entre les extrémités de deux os unissant une articulation vertébrale ou annexe d'un mammifère. Ladite prothèse est constituée de deux éléments, les éléments présentant des surfaces d'articulation coopérantes internes et des surfaces de contact avec l'os externes. Au moins un des éléments présente une section intérieure constituée de matériau rigide, relativement dur définissant une ou les surfaces d'articulation et une section extérieure constituée d'un matériau plus souple définissant la surface de contact avec l'os. Le matériau plus souple présente une caractéristique de dureté/rigidité compatible avec l'os afin de réduire l'atrophie de non usage et de répartir plus uniformément les forces des surfaces d'articulation vers l'interface osseuse associée.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67674405P | 2005-05-02 | 2005-05-02 | |
PCT/US2006/016392 WO2006119088A2 (fr) | 2005-05-02 | 2006-04-28 | Prothese pour la restauration de mouvement au niveau d'une articulation vertebrale ou annexe et espaceur intervertebral |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1879533A2 true EP1879533A2 (fr) | 2008-01-23 |
EP1879533A4 EP1879533A4 (fr) | 2011-08-03 |
Family
ID=39102546
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP06769925A Withdrawn EP1879533A4 (fr) | 2005-05-02 | 2006-04-28 | Prothese pour la restauration de mouvement |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1879533A4 (fr) |
AU (1) | AU2006242412B2 (fr) |
CA (1) | CA2605666A1 (fr) |
WO (1) | WO2006119088A2 (fr) |
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US8758443B2 (en) | 2005-05-06 | 2014-06-24 | Titan Spine, Llc | Implants with integration surfaces having regular repeating surface patterns |
US8551176B2 (en) | 2005-05-06 | 2013-10-08 | Titan Spine, Llc | Spinal implant having a passage for enhancing contact between bone graft material and cortical endplate bone |
US8591590B2 (en) | 2005-05-06 | 2013-11-26 | Titan Spine, Llc | Spinal implant having a transverse aperture |
US8617248B2 (en) | 2005-05-06 | 2013-12-31 | Titan Spine, Llc | Spinal implant having variable ratios of the integration surface area to the axial passage area |
US8435302B2 (en) | 2005-05-06 | 2013-05-07 | Titan Spine, Llc | Instruments and interbody spinal implants enhancing disc space distraction |
US8585767B2 (en) | 2005-05-06 | 2013-11-19 | Titan Spine, Llc | Endplate-preserving spinal implant with an integration plate having durable connectors |
US8562685B2 (en) | 2005-05-06 | 2013-10-22 | Titan Spine, Llc | Spinal implant and integration plate for optimizing vertebral endplate contact load-bearing edges |
US20110282454A1 (en) * | 2010-05-14 | 2011-11-17 | Titan Spine, Llc | Interbody Spinal Implant Having Internally Textured Surfaces |
US8262737B2 (en) | 2005-05-06 | 2012-09-11 | Titan Spine, Llc | Composite interbody spinal implant having openings of predetermined size and shape |
US8758442B2 (en) | 2005-05-06 | 2014-06-24 | Titan Spine, Llc | Composite implants having integration surfaces composed of a regular repeating pattern |
US11096796B2 (en) | 2005-05-06 | 2021-08-24 | Titan Spine, Llc | Interbody spinal implant having a roughened surface topography on one or more internal surfaces |
US8585766B2 (en) | 2005-05-06 | 2013-11-19 | Titan Spine, Llc | Endplate-preserving spinal implant with an integration plate having durable connectors |
US20120312779A1 (en) | 2005-05-06 | 2012-12-13 | Titian Spine, LLC | Methods for manufacturing implants having integration surfaces |
US8585765B2 (en) | 2005-05-06 | 2013-11-19 | Titan Spine, Llc | Endplate-preserving spinal implant having a raised expulsion-resistant edge |
US8562684B2 (en) | 2005-05-06 | 2013-10-22 | Titan Spine, Llc | Endplate-preserving spinal implant with an integration plate having a roughened surface topography |
US8992622B2 (en) | 2005-05-06 | 2015-03-31 | Titan Spine, Llc | Interbody spinal implant having a roughened surface topography |
WO2007075411A2 (fr) | 2005-12-16 | 2007-07-05 | Thomas Haider Patents, A Limited Liability Company | Prothèse intervertébrale pour supporter des corps vertébraux adjacents permettant la création d’une fusion molle, et méthode correspondante |
US8252058B2 (en) * | 2006-02-16 | 2012-08-28 | Amedica Corporation | Spinal implant with elliptical articulatory interface |
US20090012619A1 (en) | 2007-07-03 | 2009-01-08 | Seaspine, Inc. | Motion restoring intervertebral prosthesis with limited angular displacement |
US8696708B2 (en) | 2008-03-06 | 2014-04-15 | DePuy Synthes Products, LLC | Facet interference screw |
US20110029087A1 (en) * | 2008-04-04 | 2011-02-03 | Haider Thomas T | Intervertebral prostheses with compliant filler material for supporting adjacent vertebral bodies and method |
US8936641B2 (en) | 2008-04-05 | 2015-01-20 | DePuy Synthes Products, LLC | Expandable intervertebral implant |
JP2011526500A (ja) * | 2008-07-03 | 2011-10-13 | セラムテック ゲゼルシャフト ミット ベシュレンクテル ハフツング | 椎間板エンドプロテーゼ |
KR101107274B1 (ko) * | 2008-08-26 | 2012-01-19 | 임종완 | 요추 인공 디스크용 나사 고정체 |
US20110015752A1 (en) * | 2009-07-14 | 2011-01-20 | Biomet Manufacturing Corp. | System and Method for Acetabular Cup |
US9393129B2 (en) | 2009-12-10 | 2016-07-19 | DePuy Synthes Products, Inc. | Bellows-like expandable interbody fusion cage |
US8992619B2 (en) | 2011-11-01 | 2015-03-31 | Titan Spine, Llc | Microstructured implant surfaces |
CA2880825C (fr) | 2012-03-20 | 2021-03-16 | Titan Spine, Llc | Plaque d'extremite vertebrale d'ajustement par friction et procede de preservation de plaque d'extremite |
EP2716261A1 (fr) | 2012-10-02 | 2014-04-09 | Titan Spine, LLC | Implants avec ancrages à déploiement automatique |
US9498349B2 (en) | 2012-10-09 | 2016-11-22 | Titan Spine, Llc | Expandable spinal implant with expansion wedge and anchor |
DE112014002311A5 (de) * | 2013-05-07 | 2016-07-21 | Ceramtec Gmbh | Implantate mit Verankerungselementen |
US9615935B2 (en) | 2014-01-30 | 2017-04-11 | Titan Spine, Llc | Thermally activated shape memory spring assemblies for implant expansion |
CN105147420B (zh) * | 2014-06-03 | 2017-07-28 | 深圳兰度生物材料有限公司 | 人工椎间盘及其制备方法 |
US10940016B2 (en) | 2017-07-05 | 2021-03-09 | Medos International Sarl | Expandable intervertebral fusion cage |
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- 2006-04-28 AU AU2006242412A patent/AU2006242412B2/en not_active Ceased
- 2006-04-28 EP EP06769925A patent/EP1879533A4/fr not_active Withdrawn
- 2006-04-28 CA CA002605666A patent/CA2605666A1/fr not_active Abandoned
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Also Published As
Publication number | Publication date |
---|---|
EP1879533A4 (fr) | 2011-08-03 |
WO2006119088A3 (fr) | 2007-02-22 |
WO2006119088A2 (fr) | 2006-11-09 |
AU2006242412A1 (en) | 2006-11-09 |
CA2605666A1 (fr) | 2006-11-09 |
AU2006242412B2 (en) | 2011-12-15 |
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