EP1841864A4 - Neutralisation de charge de complexes de polyions - Google Patents

Neutralisation de charge de complexes de polyions

Info

Publication number
EP1841864A4
EP1841864A4 EP06718148A EP06718148A EP1841864A4 EP 1841864 A4 EP1841864 A4 EP 1841864A4 EP 06718148 A EP06718148 A EP 06718148A EP 06718148 A EP06718148 A EP 06718148A EP 1841864 A4 EP1841864 A4 EP 1841864A4
Authority
EP
European Patent Office
Prior art keywords
charge neutralization
polyion complexes
polyion
complexes
neutralization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06718148A
Other languages
German (de)
English (en)
Other versions
EP1841864A2 (fr
Inventor
Darren H Wakefield
David B Rozema
Jon A Wolff
Vladimir Trubetskoy
James E Hagstrom
Vladimir G Budker
Jason Klein
So Wong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arrowhead Madison Inc
Original Assignee
Mirus Bio Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/046,598 external-priority patent/US7094605B2/en
Application filed by Mirus Bio Corp filed Critical Mirus Bio Corp
Publication of EP1841864A2 publication Critical patent/EP1841864A2/fr
Publication of EP1841864A4 publication Critical patent/EP1841864A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0091—Purification or manufacturing processes for gene therapy compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP06718148A 2005-01-26 2006-01-12 Neutralisation de charge de complexes de polyions Withdrawn EP1841864A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64729305P 2005-01-26 2005-01-26
US11/046,598 US7094605B2 (en) 2001-01-02 2005-01-28 Formation of polyampholytes in the presence of a polyion
PCT/US2006/001037 WO2006081074A2 (fr) 2005-01-26 2006-01-12 Neutralisation de charge de complexes de polyions

Publications (2)

Publication Number Publication Date
EP1841864A2 EP1841864A2 (fr) 2007-10-10
EP1841864A4 true EP1841864A4 (fr) 2008-11-12

Family

ID=36740948

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06718148A Withdrawn EP1841864A4 (fr) 2005-01-26 2006-01-12 Neutralisation de charge de complexes de polyions

Country Status (2)

Country Link
EP (1) EP1841864A4 (fr)
WO (1) WO2006081074A2 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000003694A1 (fr) * 1998-07-17 2000-01-27 Mirus Corporation Inversion de charges de complexes de polyions
US20020052335A1 (en) * 1999-11-29 2002-05-02 Rozema David B. Charge reversal of polyion complexes
WO2003099228A2 (fr) * 2002-05-28 2003-12-04 Mirus Corporation Compositions et procedes d'inhibition de l'expression genetique au moyen de polynucleotides
US20040067587A1 (en) * 2002-10-04 2004-04-08 Trubetskoy Vladimir S. Process for generating multilayered particles

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003099225A2 (fr) * 2002-05-24 2003-12-04 Mirus Corporation Compositions conçues pour administrer des acides nucleiques aux cellules

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000003694A1 (fr) * 1998-07-17 2000-01-27 Mirus Corporation Inversion de charges de complexes de polyions
US20020052335A1 (en) * 1999-11-29 2002-05-02 Rozema David B. Charge reversal of polyion complexes
WO2003099228A2 (fr) * 2002-05-28 2003-12-04 Mirus Corporation Compositions et procedes d'inhibition de l'expression genetique au moyen de polynucleotides
US20040067587A1 (en) * 2002-10-04 2004-04-08 Trubetskoy Vladimir S. Process for generating multilayered particles

Also Published As

Publication number Publication date
EP1841864A2 (fr) 2007-10-10
WO2006081074A3 (fr) 2006-09-14
WO2006081074A2 (fr) 2006-08-03

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20070109

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

RIN1 Information on inventor provided before grant (corrected)

Inventor name: WAKEFIELD, DARREN, H.

Inventor name: WOLFF, JON, A.

Inventor name: BUDKER, VLADIMIR, G.

Inventor name: KLEIN, JASON

Inventor name: ROZEMA, DAVID, B.

Inventor name: WONG, SO

Inventor name: HAGSTROM, JAMES, E.

Inventor name: TRUBETSKOY, VLADIMIR

RIN1 Information on inventor provided before grant (corrected)

Inventor name: WOLFF, JON, A.

Inventor name: TRUBETSKOY, VLADIMIR

Inventor name: HAGSTROM, JAMES, E.

Inventor name: BUDKER, VLADIMIR, G.

Inventor name: ROZEMA, DAVID, B.

Inventor name: KLEIN, JASON

Inventor name: WAKEFIELD, DARREN, H.

Inventor name: WONG, SO

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20081013

17Q First examination report despatched

Effective date: 20090116

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20100803