EP1831670A4 - Dispositifs nanoelectroniques pour la detection d'adn et la reconnaissance de sequences polynucleotidiques - Google Patents

Dispositifs nanoelectroniques pour la detection d'adn et la reconnaissance de sequences polynucleotidiques

Info

Publication number
EP1831670A4
EP1831670A4 EP05855662A EP05855662A EP1831670A4 EP 1831670 A4 EP1831670 A4 EP 1831670A4 EP 05855662 A EP05855662 A EP 05855662A EP 05855662 A EP05855662 A EP 05855662A EP 1831670 A4 EP1831670 A4 EP 1831670A4
Authority
EP
European Patent Office
Prior art keywords
electrodes
dna sequence
recognition
target dna
polynucleotide sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05855662A
Other languages
German (de)
English (en)
Other versions
EP1831670A2 (fr
Inventor
Jean-Christophe P Gabriel
Shripal Gandhi
George Gruner
Charles Steven Joiner Jr
Ron Sosnowski
Alexander Star
Eugene Tu
Christian Valcke
Joseph Niemann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanomix Inc
Original Assignee
Nanomix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/212,026 external-priority patent/US20070178477A1/en
Priority claimed from US11/274,747 external-priority patent/US20070208243A1/en
Application filed by Nanomix Inc filed Critical Nanomix Inc
Publication of EP1831670A2 publication Critical patent/EP1831670A2/fr
Publication of EP1831670A4 publication Critical patent/EP1831670A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438Electrodes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6825Nucleic acid detection involving sensors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403Cells and electrode assemblies
    • G01N27/414Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4145Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS specially adapted for biomolecules, e.g. gate electrode with immobilised receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403Cells and electrode assemblies
    • G01N27/414Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4146Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS involving nanosized elements, e.g. nanotubes, nanowires
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01LSEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
    • H01L2924/00Indexing scheme for arrangements or methods for connecting or disconnecting semiconductor or solid-state bodies as covered by H01L24/00
    • H01L2924/0001Technical content checked by a classifier
    • H01L2924/0002Not covered by any one of groups H01L24/00, H01L24/00 and H01L2224/00
EP05855662A 2004-12-28 2005-12-23 Dispositifs nanoelectroniques pour la detection d'adn et la reconnaissance de sequences polynucleotidiques Withdrawn EP1831670A4 (fr)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US63995404P 2004-12-28 2004-12-28
US65727505P 2005-02-28 2005-02-28
US66887905P 2005-04-05 2005-04-05
US11/212,026 US20070178477A1 (en) 2002-01-16 2005-08-24 Nanotube sensor devices for DNA detection
US73090505P 2005-10-27 2005-10-27
US11/274,747 US20070208243A1 (en) 2002-01-16 2005-11-15 Nanoelectronic glucose sensors
US73869405P 2005-11-21 2005-11-21
US74883405P 2005-12-09 2005-12-09
PCT/US2005/047143 WO2006071895A2 (fr) 2004-12-28 2005-12-23 Dispositifs nanoelectroniques pour la detection d'adn et la reconnaissance de sequences polynucleotidiques

Publications (2)

Publication Number Publication Date
EP1831670A2 EP1831670A2 (fr) 2007-09-12
EP1831670A4 true EP1831670A4 (fr) 2010-09-15

Family

ID=36615493

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05855662A Withdrawn EP1831670A4 (fr) 2004-12-28 2005-12-23 Dispositifs nanoelectroniques pour la detection d'adn et la reconnaissance de sequences polynucleotidiques

Country Status (3)

Country Link
EP (1) EP1831670A4 (fr)
JP (1) JP2008525822A (fr)
WO (1) WO2006071895A2 (fr)

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US8154093B2 (en) 2002-01-16 2012-04-10 Nanomix, Inc. Nano-electronic sensors for chemical and biological analytes, including capacitance and bio-membrane devices
US7948041B2 (en) 2005-05-19 2011-05-24 Nanomix, Inc. Sensor having a thin-film inhibition layer
JP2008511008A (ja) * 2004-08-24 2008-04-10 ナノミックス・インコーポレーテッド Dna検出用ナノチューブセンサー装置
JP2009532064A (ja) * 2006-04-04 2009-09-10 ナノミックス・インコーポレーテッド 被検体増幅とレポーターを用いる生体分子のナノ電子的検出
ES2289948B1 (es) * 2006-07-19 2008-09-16 Starlab Barcelona, S.L. Sensor electrofisiologico.
JP5061342B2 (ja) * 2006-09-11 2012-10-31 国立大学法人大阪大学 カーボンナノチューブ電極及び当該電極を用いたセンサー
US8465634B2 (en) * 2007-05-23 2013-06-18 Arizona Board Of Regents Systems and methods for integrated electrochemical and electrical detection
WO2009026729A1 (fr) * 2007-08-30 2009-03-05 University Of Waterloo Peptides à auto-assemblage à base d'appariement d'acides aminés et procédés
JP5235215B2 (ja) * 2008-07-10 2013-07-10 株式会社イデアルスター ガスセンサー
WO2010039941A2 (fr) * 2008-10-02 2010-04-08 University Of New Haven Dispositif de détection par nanocapteur biologique
GB0822733D0 (en) * 2008-12-12 2009-01-21 Univ Warwick Nanotube electrochemistry
EP2462051A4 (fr) 2009-08-07 2013-06-26 Nanomix Inc Biodétection à base d'un nanotube de carbone magnétique
JP2011220803A (ja) * 2010-04-08 2011-11-04 Mitsumi Electric Co Ltd 電界効果トランジスタ素子を具備するバイオセンサ
US9184099B2 (en) 2010-10-04 2015-11-10 The Board Of Trustees Of The Leland Stanford Junior University Biosensor devices, systems and methods therefor
KR101963462B1 (ko) 2010-10-04 2019-03-28 제납시스 인크. 재사용 가능한 자동화 평행 생물 반응 시스템 및 방법
US9399217B2 (en) 2010-10-04 2016-07-26 Genapsys, Inc. Chamber free nanoreactor system
US9926596B2 (en) 2011-05-27 2018-03-27 Genapsys, Inc. Systems and methods for genetic and biological analysis
KR101940833B1 (ko) * 2011-05-27 2019-01-21 제납시스 인크. 유전자 및 생물학적 분석을 위한 시스템 및 방법
US8585973B2 (en) 2011-05-27 2013-11-19 The Board Of Trustees Of The Leland Stanford Junior University Nano-sensor array
CN106591103B (zh) 2011-12-01 2021-06-04 吉纳普赛斯股份有限公司 用于高效电子测序与检测的***和方法
CN104781658B (zh) 2012-10-16 2017-11-21 皇家飞利浦有限公司 具有纳米线chemfet传感器的集成电路、感测设备、测量方法及制造方法
CN102938397B (zh) * 2012-12-05 2015-09-09 苏州纳格光电科技有限公司 电子器件及其制备方法
WO2014152625A1 (fr) 2013-03-15 2014-09-25 Genapsys, Inc. Systèmes et procédés pour l'analyse biologique
JP6473444B2 (ja) * 2013-05-29 2019-02-20 シーエスアイアールCsir 電界効果トランジスタ及び複数の電界効果トランジスタを含む気体検出器
US10125393B2 (en) 2013-12-11 2018-11-13 Genapsys, Inc. Systems and methods for biological analysis and computation
WO2015086654A1 (fr) * 2013-12-12 2015-06-18 Altra Tech Limited Capteur capacitif et procédé d'utilisation
US9822401B2 (en) 2014-04-18 2017-11-21 Genapsys, Inc. Methods and systems for nucleic acid amplification
WO2016168734A1 (fr) * 2015-04-15 2016-10-20 Malcolm Alastair J Procédés de fabrication de réseaux de semi-conducteurs
WO2017033922A1 (fr) * 2015-08-24 2017-03-02 国立大学法人 東京大学 Procédé permettant de détecter une substance cible à l'aide d'un transistor à effet de champ
CN116397014A (zh) 2016-07-20 2023-07-07 测序健康公司 用于核酸测序的***和方法
EP3684951A4 (fr) 2017-09-21 2021-06-16 Genapsys, Inc. Systèmes et procédés de séquençage d'acides nucléiques
US20190219512A1 (en) * 2018-01-12 2019-07-18 Clifford H. Kern, III Device, procedure and system for detecting bacterial pathogens including methicillin-resistant staphylococcus aureus or clostridium difficile
CN113588605A (zh) * 2021-06-18 2021-11-02 山东师范大学 一种检测多种环境***的方法及其应用
US11845079B2 (en) * 2021-12-08 2023-12-19 International Business Machines Corporation Integrated silicon platform for electronic biosensors

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EP1247089B1 (fr) * 1999-12-15 2008-07-23 Board Of Trustees Of The Leland Stanford Junior University Dispositifs de nanotubes de carbone
KR20030055346A (ko) * 2000-12-11 2003-07-02 프레지던트 앤드 펠로우즈 오브 하버드 칼리지 나노센서
JP2003322653A (ja) * 2002-05-07 2003-11-14 Toshiba Corp プローブ固定支持体及びプローブ固定担体
AU2003291385A1 (en) * 2002-11-08 2004-06-03 Nanomix, Inc. Nanotube-based electronic detection of biological molecules
JP2004347532A (ja) * 2003-05-23 2004-12-09 Japan Science & Technology Agency バイオセンサー

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No further relevant documents disclosed *

Also Published As

Publication number Publication date
WO2006071895A2 (fr) 2006-07-06
WO2006071895A3 (fr) 2007-02-08
JP2008525822A (ja) 2008-07-17
EP1831670A2 (fr) 2007-09-12

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Owner name: NANOMIX, INC.

A4 Supplementary search report drawn up and despatched

Effective date: 20100818

RIC1 Information provided on ipc code assigned before grant

Ipc: C12M 3/00 20060101ALI20100812BHEP

Ipc: G01N 27/00 20060101ALI20100812BHEP

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Ipc: G01N 21/00 20060101AFI20070709BHEP

Ipc: G01N 33/543 20060101ALI20100812BHEP

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