EP1816206A4 - Method of producing uridine 5 -diphospho-n-acetylgalactosamine - Google Patents

Method of producing uridine 5 -diphospho-n-acetylgalactosamine

Info

Publication number
EP1816206A4
EP1816206A4 EP05795500A EP05795500A EP1816206A4 EP 1816206 A4 EP1816206 A4 EP 1816206A4 EP 05795500 A EP05795500 A EP 05795500A EP 05795500 A EP05795500 A EP 05795500A EP 1816206 A4 EP1816206 A4 EP 1816206A4
Authority
EP
European Patent Office
Prior art keywords
diphospho
acetylgalactosamine
producing uridine
uridine
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP05795500A
Other languages
German (de)
French (fr)
Other versions
EP1816206A1 (en
EP1816206B1 (en
Inventor
Kiyoshi Okuyama
Toshitada Noguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamasa Corp
Original Assignee
Yamasa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Corp filed Critical Yamasa Corp
Publication of EP1816206A1 publication Critical patent/EP1816206A1/en
Publication of EP1816206A4 publication Critical patent/EP1816206A4/en
Application granted granted Critical
Publication of EP1816206B1 publication Critical patent/EP1816206B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/305—Pyrimidine nucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
EP05795500.7A 2004-10-21 2005-10-18 Method of producing uridine 5 -diphospho-n-acetylgalactosamine Active EP1816206B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004306783 2004-10-21
PCT/JP2005/019081 WO2006043525A1 (en) 2004-10-21 2005-10-18 Method of producing uridine 5’-diphospho-n-acetylgalactosamine

Publications (3)

Publication Number Publication Date
EP1816206A1 EP1816206A1 (en) 2007-08-08
EP1816206A4 true EP1816206A4 (en) 2011-10-26
EP1816206B1 EP1816206B1 (en) 2017-12-13

Family

ID=36202940

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05795500.7A Active EP1816206B1 (en) 2004-10-21 2005-10-18 Method of producing uridine 5 -diphospho-n-acetylgalactosamine

Country Status (7)

Country Link
US (1) US7901912B1 (en)
EP (1) EP1816206B1 (en)
JP (1) JP4606419B2 (en)
KR (1) KR101123062B1 (en)
CN (1) CN101052724B (en)
CA (1) CA2582686C (en)
WO (1) WO2006043525A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5078080B2 (en) * 2007-07-26 2012-11-21 独立行政法人農業・食品産業技術総合研究機構 Method for producing N-acetylgalactosamine
US9290530B2 (en) 2011-07-21 2016-03-22 The Regents Of The University Of California Chemoenzymatic synthesis of heparin and heparan sulfate analogs
WO2013013244A2 (en) * 2011-07-21 2013-01-24 The Regents Of The University Of California Chemoenzymatic synthesis of heparin and haparan sulfate analogs
CN102409070A (en) * 2011-09-15 2012-04-11 山东大学 Preparation method of rare sugar nucleotides
EP3819381A1 (en) * 2019-11-05 2021-05-12 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Enzymatic method for preparation of udp-galactose
CN111500660A (en) * 2020-04-23 2020-08-07 武汉糖智药业有限公司 Synthesis method of monosialotetrahexosyl ganglioside
CN112457355B (en) * 2020-11-20 2022-06-07 武汉糖智药业有限公司 Sugar nucleotide separation and purification method
CN113481180A (en) * 2021-07-05 2021-10-08 吉林大学 Alkaline thermophilic inorganic pyrophosphatase and application thereof in enhancing polymerase chain reaction and UDP-galactose synthesis reaction
CN114774495A (en) * 2022-04-21 2022-07-22 山东大学 Double-enzyme co-immobilization synthesis method of uridine diphosphate-N-acetylglucosamine

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516665A (en) * 1993-09-13 1996-05-14 The Scripps Research Institute N-acetylgalactosaminyl or N-acetylglucosaminyl transfer using N-acetylglucosaminyl-1-phosphate or N-acetylgalactosaminyl-1-phosphate as precursor and glycosyl-nucleotide regeneration
WO1998033894A1 (en) * 1997-01-29 1998-08-06 Forschungszentrum Jülich GmbH Method for the production of ndp-sugar

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1167804C (en) * 1997-08-29 2004-09-22 雅玛山酱油株式会社 Process for producing uridine diphosphate-N-acetyl-glucosamine
US7244601B2 (en) * 1997-12-15 2007-07-17 National Research Council Of Canada Fusion proteins for use in enzymatic synthesis of oligosaccharides
AU2002225352A1 (en) 2000-12-21 2002-07-01 Kyowa Hakko Kogyo Co. Ltd. Process for producing udp-n-acetylgalactosamine and saccharide containing n-acetylgalactosamine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516665A (en) * 1993-09-13 1996-05-14 The Scripps Research Institute N-acetylgalactosaminyl or N-acetylglucosaminyl transfer using N-acetylglucosaminyl-1-phosphate or N-acetylgalactosaminyl-1-phosphate as precursor and glycosyl-nucleotide regeneration
WO1998033894A1 (en) * 1997-01-29 1998-08-06 Forschungszentrum Jülich GmbH Method for the production of ndp-sugar

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2006043525A1 *

Also Published As

Publication number Publication date
KR101123062B1 (en) 2012-03-15
WO2006043525A1 (en) 2006-04-27
EP1816206A1 (en) 2007-08-08
CN101052724B (en) 2012-09-05
EP1816206B1 (en) 2017-12-13
JPWO2006043525A1 (en) 2008-05-22
US7901912B1 (en) 2011-03-08
KR20070068365A (en) 2007-06-29
CN101052724A (en) 2007-10-10
CA2582686A1 (en) 2006-04-27
CA2582686C (en) 2013-08-06
JP4606419B2 (en) 2011-01-05

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