EP1815905A3 - Mixing device - Google Patents

Mixing device Download PDF

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Publication number
EP1815905A3
EP1815905A3 EP07001573A EP07001573A EP1815905A3 EP 1815905 A3 EP1815905 A3 EP 1815905A3 EP 07001573 A EP07001573 A EP 07001573A EP 07001573 A EP07001573 A EP 07001573A EP 1815905 A3 EP1815905 A3 EP 1815905A3
Authority
EP
European Patent Office
Prior art keywords
receiving plate
bearing elements
microplate
motor
sample containers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07001573A
Other languages
German (de)
French (fr)
Other versions
EP1815905A2 (en
Inventor
Klaus Dipl.-Ing. Hafner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Berthold Technologies GmbH and Co KG
Original Assignee
Berthold Technologies GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berthold Technologies GmbH and Co KG filed Critical Berthold Technologies GmbH and Co KG
Publication of EP1815905A2 publication Critical patent/EP1815905A2/en
Publication of EP1815905A3 publication Critical patent/EP1815905A3/en
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20—Mixing the contents of independent containers, e.g. test tubes
    • B01F31/22—Mixing the contents of independent containers, e.g. test tubes with supporting means moving in a horizontal plane, e.g. describing an orbital path for moving the containers about an axis which intersects the receptacle axis at an angle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20—Mixing the contents of independent containers, e.g. test tubes
    • B01F31/265—Mixing the contents of independent containers, e.g. test tubes the vibrations being caused by an unbalanced rotating member
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L99/00—Subject matter not provided for in other groups of this subclass

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)

Abstract

Eine Vorrichtung zum Mischen flüssiger Substanzen oder Verteilung von festen Substanzen in flüssigen Substanzen in mehreren in einer Mikroplatte (7) angeordneten Probenbehältern ist auf einer horizontal verschiebbaren Aufnahmeplatte (2) gehalten. Ein mit einer Unwucht versehener Motor (3) ist mittels seines Stators (3A) über einem Grundgestell (1) unmittelbar an der Unterseite der Aufnahmeplatte (2) gehalten, wobei die Drehachse (D) des Rotors (3B) senkrecht zur Aufnahmeplatte (2) angeordnet ist. Die Aufnahmeplatte (2) mit dem Motor (3) liegt auf mindestens drei horizontal elastisch bewegbaren Lagerelementen (6) auf, deren Befestigungspunkte am Grundgestell (1) und an der Aufnahmeplatte (2) so gewählt sind, dass die Aufnahmeplatte (2) mit der Mikroplatte (7) infolge der Rückstellkraft der Lagerelemente (6) im Ruhezustand eine definierte Position in der X-Y-Ebene einnimmt, und im Schüttelzustand infolge der von der Unwucht des Motors (3) bewirkten, gleich gerichteten seitlichen Auslenkung der Lagerelemente (6) eine horizontale, verdrehfreie Schüttelbewegung gegen die Rückstellkraft der Lagerelemente ausführt. Hierbei beschreiben alle Probenbehälter der Mikroplatte (7) die gleiche Kreisbahn in der X-Y-Ebene und es erfolgt der gleiche Energieeintrag zum Mischen in alle Probenbehälter.

Figure imgaf001
A device for mixing liquid substances or distributing solid substances in liquid substances in a plurality of sample containers arranged in a microplate (7) is held on a horizontally displaceable receiving plate (2). A motor (3) provided with an imbalance is held by means of its stator (3A) above a base frame (1) directly on the underside of the receiving plate (2), the axis of rotation (D) of the rotor (3B) being perpendicular to the receiving plate (2). is arranged. The receiving plate (2) with the motor (3) rests on at least three horizontally elastically movable bearing elements (6) whose attachment points on the base frame (1) and on the receiving plate (2) are selected so that the receiving plate (2) with the Microplate (7) due to the restoring force of the bearing elements (6) assumes a defined position in the XY plane in the idle state, and in the shaking state as a result of the imbalance of the motor (3) caused, the same directional lateral deflection of the bearing elements (6) has a horizontal , rotatable shaking movement against the restoring force of the bearing elements performs. In this case, all the sample containers of the microplate (7) describe the same circular path in the XY plane and the same energy input takes place for mixing into all sample containers.
Figure imgaf001
EP07001573A 2006-02-01 2007-01-25 Mixing device Withdrawn EP1815905A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE202006001514U DE202006001514U1 (en) 2006-02-01 2006-02-01 mixing device

Publications (2)

Publication Number Publication Date
EP1815905A2 EP1815905A2 (en) 2007-08-08
EP1815905A3 true EP1815905A3 (en) 2008-03-12

Family

ID=36217860

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07001573A Withdrawn EP1815905A3 (en) 2006-02-01 2007-01-25 Mixing device

Country Status (3)

Country Link
US (1) US7338199B2 (en)
EP (1) EP1815905A3 (en)
DE (1) DE202006001514U1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107855053A (en) * 2017-11-24 2018-03-30 上海骐钛机械有限公司 A kind of flask for medicinal preparations rocking equipment

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DE10232202B4 (en) * 2002-07-16 2005-08-25 H+P Labortechnik Ag Sample treatment station
EP1443101B1 (en) * 2002-12-18 2012-02-22 Liconic Ag Incubator with moveable support
ATE396250T1 (en) * 2005-05-09 2008-06-15 Liconic Ag STORAGE DEVICE FOR LABORATORY SAMPLES WITH STORAGE SHAFT AND SHAKER DRIVE
DE202006001514U1 (en) * 2006-02-01 2006-04-06 Berthold Technologies Gmbh & Co. Kg mixing device
DE102006011370A1 (en) * 2006-03-09 2007-09-20 Eppendorf Ag Device for mixing, in particular, laboratory vessel contents with a sensor
DE102006062714B4 (en) * 2006-03-09 2013-02-21 Eppendorf Ag Device for mixing laboratory vessel contents
EP1850136A1 (en) * 2006-04-28 2007-10-31 F.Hoffmann-La Roche Ag Shaker device for analyzer apparatus and analyzer comprising such a device
DE102006030056B3 (en) * 2006-06-29 2007-06-21 Ika - Werke Gmbh & Co. Kg Microtiter plate comprises wells with deformable bases and stirrer rods that are connected to or pass through the well bases and comprise an outer section in contact with a drive unit
DE102007010616A1 (en) * 2007-03-02 2008-09-04 Eppendorf Ag Mixer with a number of positions, for mixing the contents of laboratory vessels, has adapters to hold the vessels for rotary oscillation against each other on a horizontal plane
WO2009131700A2 (en) * 2008-04-25 2009-10-29 Envia Systems, Inc. High energy lithium ion batteries with particular negative electrode compositions
WO2010119396A1 (en) * 2009-04-15 2010-10-21 Koninklijke Philips Electronics N.V. Cartridge for an amplification process
EP2316563A1 (en) * 2009-10-28 2011-05-04 Roche Diagnostics GmbH Method for detecting analytes in a fluid sample and device for carrying out the method
US8534905B2 (en) * 2010-05-24 2013-09-17 New Brunswick Scientific Co., Inc. Adjustable orbit imbalance compensating orbital shaker
US8226291B2 (en) * 2010-05-24 2012-07-24 New Brunswick Scientific Co., Inc. Adjustable orbit imbalance compensating orbital shaker
EP2669000B1 (en) * 2010-11-03 2019-05-01 Eppendorf Ag Mixing device with a bearing for a holder device, related mixing method and use of the mixing device
US9504981B2 (en) * 2013-05-15 2016-11-29 True Health Diagnostics Llc Methods for purifying nucleic acids and devices thereof
FR3011488A1 (en) * 2013-10-07 2015-04-10 Aelorve DEVICE FOR MIXING A VOLUME OF LIQUID
EP3081627A4 (en) * 2013-12-12 2017-01-25 Yamaha Hatsudoki Kabushiki Kaisha Well plate and subject selection device provided with well plate
GB201400836D0 (en) 2014-01-17 2014-03-05 Ttp Labtech Ltd Microplate content agitation apparatus and method
KR102665867B1 (en) * 2015-04-06 2024-05-10 메소 스케일 테크놀러지즈, 엘엘시 High throughput system for performing assays using electrochemiluminescence including a consumable shaking apparatus
CN107413261A (en) * 2016-05-23 2017-12-01 济南市中心医院 A kind of automatic rocking evenly machine for decoction mixed configuration
US10399048B2 (en) * 2017-08-03 2019-09-03 Agilent Technologies, Inc. Sample processing apparatus with integrated heater, shaker and magnet
CN107746949B (en) * 2017-10-24 2019-05-21 毛思静 A kind of rare earth processing Extractant of Rare Earth Elements rapid configuration equipment
CN108860609B (en) * 2018-06-28 2021-08-03 河南财经政法大学 Unmanned aerial vehicle agricultural seeding robot
JP7178012B2 (en) * 2018-10-29 2022-11-25 学校法人 中央大学 Liquid mixing device and liquid mixing method
CN109499455B (en) * 2018-11-26 2021-06-11 山东碧奥生物科技有限公司 Chemical reagent mixing reaction device
USD914231S1 (en) 2019-11-20 2021-03-23 Agilent Technologies, Inc. Sample processing apparatus
USD917063S1 (en) 2019-11-20 2021-04-20 Agilent Technologies, Inc. Sample processing apparatus
CN112808116A (en) * 2021-01-14 2021-05-18 桂林优利特医疗电子有限公司 Micropore plate mixing mechanism
US11808354B2 (en) 2021-03-11 2023-11-07 Sartorius Bioanalytical Instruments, Inc. Sample shaker system with sealed airflow

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL43283C (en) * 1900-01-01
US2247978A (en) * 1940-04-18 1941-07-01 Arthur H Thomas Company Shaker
DE1913374A1 (en) * 1968-03-28 1969-10-09 Simon Jacot Device for deburring, smoothing, polishing and mixing
JPS51114767A (en) * 1975-03-31 1976-10-08 Fujirebio Inc Vibrator
US4118801A (en) * 1976-11-05 1978-10-03 Kraft Jack A Rack for vessels and means for agitating the vessels in the rack
EP0679430A1 (en) * 1994-04-26 1995-11-02 David John Fletcher Orbital shaking device
EP1393797A2 (en) * 2002-08-29 2004-03-03 Heidolph Instruments GmbH & Co.KG Shaking and mixing apparatus
DE202006005813U1 (en) * 2006-04-10 2006-07-06 Franz Banke Gmbh Gypsum mixer has means for mixing-through of gypsum suspension formed by movement mechanism which sets mixing container in motion so that it experiences a regular direction change
WO2007054646A1 (en) * 2005-11-10 2007-05-18 Maxmat Sa Support carriage for vessels for a biological analysis apparatus

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US3281125A (en) * 1965-10-21 1966-10-25 Flexicore Co Vibrator mechanism
US3635446A (en) * 1970-07-27 1972-01-18 Yoshinori Kurosawa Liquids shaking device
US4619532A (en) * 1984-11-29 1986-10-28 Everett Douglas Hougen Shaker for paint containers
US4702610A (en) * 1985-04-18 1987-10-27 Reynolds Jr Albert B Undulating mixing device
JPH0661438B2 (en) * 1986-02-19 1994-08-17 タイテック株式会社 Shaker
JPS637829A (en) * 1986-06-30 1988-01-13 Taiyo Kagaku Kogyo Kk Rotating and reciprocating changeover type shaking machine
JPH0628715B2 (en) * 1989-01-17 1994-04-20 タイテック株式会社 Reciprocating and turning switch type shaker
GB9008827D0 (en) * 1990-04-19 1990-06-13 Fisons Plc Device
GB2277043B (en) * 1993-04-13 1996-10-30 David John Fletcher Orbital shaking attachment
US5921676A (en) * 1998-01-26 1999-07-13 Stovall Life Science, Inc. Undulating mixing device with adjustable tilt and method
WO1999054061A1 (en) * 1998-04-21 1999-10-28 Eyela-Chino Inc. Shaking machine
US6299344B1 (en) * 1998-10-05 2001-10-09 New Brunswick Scientific Company Flexible band reciprocating shaker
US7270472B2 (en) * 2005-02-23 2007-09-18 Bose Corporation Resonant shaking
DE202006001514U1 (en) * 2006-02-01 2006-04-06 Berthold Technologies Gmbh & Co. Kg mixing device

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL43283C (en) * 1900-01-01
US2247978A (en) * 1940-04-18 1941-07-01 Arthur H Thomas Company Shaker
DE1913374A1 (en) * 1968-03-28 1969-10-09 Simon Jacot Device for deburring, smoothing, polishing and mixing
JPS51114767A (en) * 1975-03-31 1976-10-08 Fujirebio Inc Vibrator
US4118801A (en) * 1976-11-05 1978-10-03 Kraft Jack A Rack for vessels and means for agitating the vessels in the rack
EP0679430A1 (en) * 1994-04-26 1995-11-02 David John Fletcher Orbital shaking device
EP1393797A2 (en) * 2002-08-29 2004-03-03 Heidolph Instruments GmbH & Co.KG Shaking and mixing apparatus
WO2007054646A1 (en) * 2005-11-10 2007-05-18 Maxmat Sa Support carriage for vessels for a biological analysis apparatus
DE202006005813U1 (en) * 2006-04-10 2006-07-06 Franz Banke Gmbh Gypsum mixer has means for mixing-through of gypsum suspension formed by movement mechanism which sets mixing container in motion so that it experiences a regular direction change

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107855053A (en) * 2017-11-24 2018-03-30 上海骐钛机械有限公司 A kind of flask for medicinal preparations rocking equipment

Also Published As

Publication number Publication date
EP1815905A2 (en) 2007-08-08
US20070177457A1 (en) 2007-08-02
DE202006001514U1 (en) 2006-04-06
US7338199B2 (en) 2008-03-04

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