EP1802560A4 - Halocombstatins and methods of synthesis thereof - Google Patents

Halocombstatins and methods of synthesis thereof

Info

Publication number
EP1802560A4
EP1802560A4 EP05816139A EP05816139A EP1802560A4 EP 1802560 A4 EP1802560 A4 EP 1802560A4 EP 05816139 A EP05816139 A EP 05816139A EP 05816139 A EP05816139 A EP 05816139A EP 1802560 A4 EP1802560 A4 EP 1802560A4
Authority
EP
European Patent Office
Prior art keywords
halocombstatins
synthesis
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05816139A
Other languages
German (de)
French (fr)
Other versions
EP1802560A2 (en
Inventor
George R Pettit
Heidi J Rosenberg
Matthew D Minardi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arizona Board of Regents of ASU
Original Assignee
Arizona Board of Regents of ASU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/948,926 external-priority patent/US7223747B2/en
Application filed by Arizona Board of Regents of ASU filed Critical Arizona Board of Regents of ASU
Publication of EP1802560A2 publication Critical patent/EP1802560A2/en
Publication of EP1802560A4 publication Critical patent/EP1802560A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
EP05816139A 2004-09-24 2005-09-23 Halocombstatins and methods of synthesis thereof Withdrawn EP1802560A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61288804P 2004-09-24 2004-09-24
US10/948,926 US7223747B2 (en) 2003-09-24 2004-09-24 Halocombstatins and methods of synthesis thereof
PCT/US2005/033998 WO2006036743A2 (en) 2004-09-24 2005-09-23 Halocombstatins and methods of synthesis thereof

Publications (2)

Publication Number Publication Date
EP1802560A2 EP1802560A2 (en) 2007-07-04
EP1802560A4 true EP1802560A4 (en) 2010-03-31

Family

ID=36119428

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05816139A Withdrawn EP1802560A4 (en) 2004-09-24 2005-09-23 Halocombstatins and methods of synthesis thereof

Country Status (5)

Country Link
EP (1) EP1802560A4 (en)
JP (1) JP2008514614A (en)
AU (1) AU2005289773A1 (en)
CA (1) CA2582046A1 (en)
WO (1) WO2006036743A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101085743B (en) * 2006-06-06 2012-02-15 浙江大德药业集团有限公司 Fluorine-containing alkoxy combretastatin derivative, preparation method and use thereof
TW200819409A (en) * 2006-10-19 2008-05-01 Univ Taipei Medical Z-stilbenes derivatives and the pharmaceutical composition thereof
US20180030095A1 (en) 2015-02-13 2018-02-01 George Robert Pettit Silstatin compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002050007A2 (en) * 2000-12-21 2002-06-27 Cancer Research Technology Limited Substituted stilbenes, their reactions and anticancer activity
JP2005507912A (en) * 2001-10-26 2005-03-24 オキシジーン， インコーポレイテッド Functionalized stilbene derivatives as improved vascular targeting agents
AU2002319899A1 (en) * 2002-06-25 2004-01-06 Raju Gokaraju Ganga Novel resveratrol analogs

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MUGABE, TRAWICK, MONK, SILES, MALLINATH, GARNER, KANE, PINNEY: "Biological evaluation of mono and dichloro-substituted combretastatin analogs as inhibitors of tubulin polymerization", FASEB JOURNAL, vol. 19, 4 March 2005 (2005-03-04), pages A276 - A277, XP009122799 *

Also Published As

Publication number Publication date
CA2582046A1 (en) 2006-04-06
EP1802560A2 (en) 2007-07-04
AU2005289773A1 (en) 2006-04-06
WO2006036743A2 (en) 2006-04-06
WO2006036743A3 (en) 2006-05-26
JP2008514614A (en) 2008-05-08

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20070424

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20100302

17Q First examination report despatched

Effective date: 20100607

RIC1 Information provided on ipc code assigned before grant

Ipc: C07C 43/23 20060101AFI20120125BHEP

Ipc: C07F 9/12 20060101ALI20120125BHEP

Ipc: C07C 43/00 20060101ALI20120125BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20120403