EP1691609A4 - Delivery of viral vectors to extravascular parenchymal cells - Google Patents

Delivery of viral vectors to extravascular parenchymal cells

Info

Publication number
EP1691609A4
EP1691609A4 EP04709076A EP04709076A EP1691609A4 EP 1691609 A4 EP1691609 A4 EP 1691609A4 EP 04709076 A EP04709076 A EP 04709076A EP 04709076 A EP04709076 A EP 04709076A EP 1691609 A4 EP1691609 A4 EP 1691609A4
Authority
EP
European Patent Office
Prior art keywords
delivery
viral vectors
parenchymal cells
extravascular
extravascular parenchymal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04709076A
Other languages
German (de)
French (fr)
Other versions
EP1691609A1 (en
Inventor
Jon A Wolff
Vladimir G Budker
James E Hagstrom
Hans Herweijer
Julia Hegge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arrowhead Madison Inc
Original Assignee
Mirus Bio Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mirus Bio Corp filed Critical Mirus Bio Corp
Publication of EP1691609A1 publication Critical patent/EP1691609A1/en
Publication of EP1691609A4 publication Critical patent/EP1691609A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0075—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0083—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the administration regime

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP04709076A 2003-12-11 2004-02-06 Delivery of viral vectors to extravascular parenchymal cells Withdrawn EP1691609A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77370603A 2003-12-11 2003-12-11
PCT/US2004/003506 WO2005060746A1 (en) 2003-12-11 2004-02-06 Delivery of viral vectors to extravascular parenchymal cells

Publications (2)

Publication Number Publication Date
EP1691609A1 EP1691609A1 (en) 2006-08-23
EP1691609A4 true EP1691609A4 (en) 2006-11-29

Family

ID=34711827

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04709076A Withdrawn EP1691609A4 (en) 2003-12-11 2004-02-06 Delivery of viral vectors to extravascular parenchymal cells

Country Status (2)

Country Link
EP (1) EP1691609A4 (en)
WO (1) WO2005060746A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2658628A1 (en) * 2006-07-25 2008-01-31 Celladon Corporation Extended antegrade epicardial coronary infusion of adeno-associated viral vectors for gene therapy
JP2011512408A (en) 2008-02-19 2011-04-21 セラドン・コーポレーション Composition for increasing viral vector uptake into the myocardium
WO2013119880A1 (en) * 2012-02-07 2013-08-15 Global Bio Therapeutics Usa, Inc. Compartmentalized method of nucleic acid delivery and compositions and uses thereof
EP2933335A1 (en) * 2014-04-18 2015-10-21 Genethon A method of treating peripheral neuropathies and motor neuron diseases

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999021982A1 (en) * 1997-10-27 1999-05-06 Hunan Medical University Human m6b1 gene
WO1999055379A1 (en) * 1998-04-30 1999-11-04 Mirus Corporation A process of delivering a polynucleotide to a cell via the vascular system

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3972893A (en) * 1992-04-03 1993-11-08 Baylor College Of Medicine Gene therapy using the intestine
US6379966B2 (en) * 1999-02-26 2002-04-30 Mirus Corporation Intravascular delivery of non-viral nucleic acid

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999021982A1 (en) * 1997-10-27 1999-05-06 Hunan Medical University Human m6b1 gene
WO1999055379A1 (en) * 1998-04-30 1999-11-04 Mirus Corporation A process of delivering a polynucleotide to a cell via the vascular system

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BUDKER V ET AL: "THE EFFICIENT EXPRESSION OF INTRAVASCULARLY DELIVERED DNA IN RAT MUSCLE", GENE THERAPY, MACMILLAN PRESS LTD., BASINGSTOKE, GB, vol. 5, no. 2, February 1998 (1998-02-01), pages 272 - 276, XP002921644, ISSN: 0969-7128 *
GREELISH J P ET AL: "STABLE RESTORATION OF THE SARCOGLYCAN COMPLEX IN DYSTROPHIC MUSCLE PERFUSED WITH HISTAMINE AND A RECOMBINANT ADENO-ASSOCIATED VIRAL VECTOR", NATURE MEDICINE, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 5, no. 4, April 1999 (1999-04-01), pages 439 - 443, XP002920731, ISSN: 1078-8956 *
See also references of WO2005060746A1 *

Also Published As

Publication number Publication date
WO2005060746A1 (en) 2005-07-07
EP1691609A1 (en) 2006-08-23

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20040817

AK Designated contracting states

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

A4 Supplementary search report drawn up and despatched

Effective date: 20061031

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 48/00 20060101AFI20061025BHEP

DAX Request for extension of the european patent (deleted)
17Q First examination report despatched

Effective date: 20070620

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18D Application deemed to be withdrawn

Effective date: 20090211