EP1631309A4 - Protein kinase c peptides for use in withdrawal - Google Patents

Protein kinase c peptides for use in withdrawal

Info

Publication number
EP1631309A4
EP1631309A4 EP03731305A EP03731305A EP1631309A4 EP 1631309 A4 EP1631309 A4 EP 1631309A4 EP 03731305 A EP03731305 A EP 03731305A EP 03731305 A EP03731305 A EP 03731305A EP 1631309 A4 EP1631309 A4 EP 1631309A4
Authority
EP
European Patent Office
Prior art keywords
withdrawal
peptides
protein kinase
kinase
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03731305A
Other languages
German (de)
French (fr)
Other versions
EP1631309A2 (en
Inventor
Daria Mochly-Rosen
Joan J Kendig
Sarah M Sweitzer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Publication of EP1631309A2 publication Critical patent/EP1631309A2/en
Publication of EP1631309A4 publication Critical patent/EP1631309A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11—Protein-serine/threonine kinases (2.7.11)
    • C12Y207/11013—Protein kinase C (2.7.11.13)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Addiction (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
EP03731305A 2003-05-16 2003-05-16 Protein kinase c peptides for use in withdrawal Withdrawn EP1631309A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2003/016070 WO2004103266A2 (en) 2003-05-16 2003-05-16 Protein kinase c peptides for use in withdrawal

Publications (2)

Publication Number Publication Date
EP1631309A2 EP1631309A2 (en) 2006-03-08
EP1631309A4 true EP1631309A4 (en) 2010-04-28

Family

ID=33476226

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03731305A Withdrawn EP1631309A4 (en) 2003-05-16 2003-05-16 Protein kinase c peptides for use in withdrawal

Country Status (5)

Country Link
EP (1) EP1631309A4 (en)
JP (1) JP4675109B2 (en)
AU (1) AU2003241559A1 (en)
CA (1) CA2524818A1 (en)
WO (1) WO2004103266A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000001805A1 (en) * 1998-07-06 2000-01-13 Messing Robert O Cells and animals deficient in protein kinase c epsilon
US6376467B1 (en) * 1998-10-09 2002-04-23 The Regents Of The University Of California Use of inhibitors of protein kinase C epsilon to treat pain
WO2003089457A2 (en) * 2002-04-22 2003-10-30 The Board Of Trustees Of The Leland Stanford Junior University Peptide inhibitors of protein kinase c ϝ for pain management

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ508767A (en) * 1998-07-06 2003-12-19 Robert O Use of inhibitors of protein kinase c epsilon to treat pain
ATE276754T1 (en) * 1998-07-21 2004-10-15 Cytovia Inc NEW FLUORESCENCE DYES AND THEIR APPLICATION IN WHOLE CELL FLUORESCENCE DETECTION PROCEDURES FOR CASPASES, PEPTIDASES, PROTEASES AND OTHER ENZYMES AND THEIR USE

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000001805A1 (en) * 1998-07-06 2000-01-13 Messing Robert O Cells and animals deficient in protein kinase c epsilon
US20020124272A1 (en) * 1998-07-06 2002-09-05 Robert O. Messing Protein kinase c epsilon as modulator of anxiety, alcohol consumption and self-administration of drugs of abuse
US6376467B1 (en) * 1998-10-09 2002-04-23 The Regents Of The University Of California Use of inhibitors of protein kinase C epsilon to treat pain
WO2003089457A2 (en) * 2002-04-22 2003-10-30 The Board Of Trustees Of The Leland Stanford Junior University Peptide inhibitors of protein kinase c ϝ for pain management

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 2002, LI H. F. ET AL.: "PROTEIN KINASE Cgamma MEDIATES ETHANOL WITHDRAWAL HYPERRESPONSIVENESS IN SPINAL CORD MOTOR NEURONS: ELECTROPHYSIOLOGICAL AND IMMUNOCYTOCHEMICAL STUDY.", XP002570924, Database accession no. PREV200300314670 *
SOCIETY FOR NEUROSCIENCE ABSTRACT VIEWER AND ITINERARY PLANNER, vol. 2002, 2002, 32ND ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE; ORLANDO, FLORIDA, USA; NOVEMBER 02-07, 2002, pages Abstract No. 545.2 URL - http://sf *
SWEITZER S. M. ET AL.: "DEVELOPMENTAL REGULATION OF INFLAMMATORY PAIN BY PROTEIN KINASE C", ABSTRACTS OF THE ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE, SOCIETY FOR NEUROSCIENCE, WASHINGTON, DC, US, 2 November 2002 (2002-11-02), XP008079891, ISSN: 0190-5295 *
SWEITZER S. M. ET AL.: "Protein kinase c epsilon and gamma: roles in age-specific modulation of acute opioid-withdrawal allodynia", SEMINARS IN PAIN MEDICINE, SAUNDERS, US, vol. 1, no. 4, 1 December 2003 (2003-12-01), pages 206 - 219, XP004665975, ISSN: 1537-5897 *

Also Published As

Publication number Publication date
CA2524818A1 (en) 2004-12-02
WO2004103266A2 (en) 2004-12-02
WO2004103266A8 (en) 2005-10-20
EP1631309A2 (en) 2006-03-08
AU2003241559A1 (en) 2004-12-13
JP2006525948A (en) 2006-11-16
WO2004103266A3 (en) 2005-03-24
JP4675109B2 (en) 2011-04-20

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20051216

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

A4 Supplementary search report drawn up and despatched

Effective date: 20100330

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20111201