EP1545493A4 - METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NEOVASCULARIZATION - Google Patents
METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NEOVASCULARIZATIONInfo
- Publication number
- EP1545493A4 EP1545493A4 EP03767196A EP03767196A EP1545493A4 EP 1545493 A4 EP1545493 A4 EP 1545493A4 EP 03767196 A EP03767196 A EP 03767196A EP 03767196 A EP03767196 A EP 03767196A EP 1545493 A4 EP1545493 A4 EP 1545493A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- neovascularization
- compositions
- methods
- conditions associated
- treat conditions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/26—Cyanate or isocyanate esters; Thiocyanate or isothiocyanate esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40113002P | 2002-08-05 | 2002-08-05 | |
US401130P | 2002-08-05 | ||
PCT/US2003/024455 WO2004012677A2 (en) | 2002-08-05 | 2003-08-05 | Methods and compositions to treat conditions associated with neovascularization |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1545493A2 EP1545493A2 (en) | 2005-06-29 |
EP1545493A4 true EP1545493A4 (en) | 2006-01-11 |
Family
ID=31495928
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP03767196A Withdrawn EP1545493A4 (en) | 2002-08-05 | 2003-08-05 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NEOVASCULARIZATION |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1545493A4 (ja) |
JP (1) | JP2006508047A (ja) |
CN (1) | CN1723017A (ja) |
AU (1) | AU2003263988A1 (ja) |
TW (1) | TW200407119A (ja) |
WO (1) | WO2004012677A2 (ja) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0417987A (pt) * | 2003-12-22 | 2007-04-27 | Alcon Inc | agentes para o tratamento de retinopatia glaucomatosa e de neuropatia óptica |
KR20080045083A (ko) * | 2005-04-29 | 2008-05-22 | 존스 홉킨스 유니버시티 | Uv광-유발 피부 발암현상의 억제 방법 |
WO2007130353A2 (en) * | 2006-05-01 | 2007-11-15 | Johns Hopkins University | Phase 2 inducers, ppar-alpha agonists and related signalling pathways protect cartilage against inflammation, apoptosis and stress |
JP2011500680A (ja) * | 2007-10-16 | 2011-01-06 | ジョンズ・ホプキンス・ユニヴァーシティ | 放射線傷害から皮膚を保護する方法 |
GB0811992D0 (en) * | 2008-07-01 | 2008-08-06 | Mithen Richard | Treatment |
WO2016007581A1 (en) * | 2014-07-09 | 2016-01-14 | Mccord Darlene E | Compositions for anti-inflammatory, antioxidant effects and improved respiratory function by specific histone deacetylase inhibition |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000045829A1 (en) * | 1999-02-02 | 2000-08-10 | Wassen International Limited | Brassica extracts or sulforaphane in combination with resveratrol as antitumor agents |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5411986A (en) | 1993-03-12 | 1995-05-02 | The Johns Hopkins University | Chemoprotective isothiocyanates |
US6433011B1 (en) * | 2000-03-08 | 2002-08-13 | American Health Foundation | Method for inhibiting formation of aberrant crypt foci in the colon of a mammal |
-
2003
- 2003-08-05 TW TW092121415A patent/TW200407119A/zh unknown
- 2003-08-05 WO PCT/US2003/024455 patent/WO2004012677A2/en active Application Filing
- 2003-08-05 AU AU2003263988A patent/AU2003263988A1/en not_active Abandoned
- 2003-08-05 CN CNA038237474A patent/CN1723017A/zh active Pending
- 2003-08-05 JP JP2004526444A patent/JP2006508047A/ja active Pending
- 2003-08-05 EP EP03767196A patent/EP1545493A4/en not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000045829A1 (en) * | 1999-02-02 | 2000-08-10 | Wassen International Limited | Brassica extracts or sulforaphane in combination with resveratrol as antitumor agents |
Non-Patent Citations (7)
Title |
---|
CHIAO J W ET AL: "Sulforaphane and its metabolite mediate growth arrest and apoptosis in human prostate cancer cells", INTERNATIONAL JOURNAL OF ONCOLOGY, vol. 20, no. 3, March 2002 (2002-03-01), pages 631 - 636, XP009056886, ISSN: 1019-6439 * |
FIMOGNARI CARMELA ET AL: "Growth inhibition, cell-cycle arrest and apoptosis in human T-cell leukemia by the isothiocyanate sulforaphane", CARCINOGENESIS (OXFORD), vol. 23, no. 4, April 2002 (2002-04-01), pages 581 - 586, XP002353392, ISSN: 0143-3334 * |
GAMET-PAYRASTRE LAURENCE ET AL: "Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells", CANCER RESEARCH, vol. 60, no. 5, 1 March 2000 (2000-03-01), pages 1426 - 1433, XP002353391, ISSN: 0008-5472 * |
LUND ELIZABETH K ET AL: "Cell death in the colorectal cancer cell line HT29 in response to glucosinolate metabolites", JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, vol. 81, no. 9, July 2001 (2001-07-01), pages 959 - 961, XP002353393, ISSN: 0022-5142 * |
MATUSHESKI NATHAN V ET AL: "Comparison of the bioactivity of two glucoraphanin hydrolysis products found in broccoli, sulforaphane and sulforaphane nitrile", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 49, no. 12, December 2001 (2001-12-01), pages 5743 - 5749, XP002353573, ISSN: 0021-8561 * |
See also references of WO2004012677A2 * |
ZHANG YUESHENG; KENSLER THOMAS W; CHO CHEON-GYU; POSNER GARY H; TALALAY PAUL: "Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates", PROC. NATL. ACAD. SCI, vol. 91, no. 8, 1994, pages 3147 - 3150 * |
Also Published As
Publication number | Publication date |
---|---|
WO2004012677A3 (en) | 2005-02-24 |
WO2004012677A2 (en) | 2004-02-12 |
AU2003263988A8 (en) | 2004-02-23 |
EP1545493A2 (en) | 2005-06-29 |
TW200407119A (en) | 2004-05-16 |
JP2006508047A (ja) | 2006-03-09 |
CN1723017A (zh) | 2006-01-18 |
AU2003263988A1 (en) | 2004-02-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20050303 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20051124 |
|
17Q | First examination report despatched |
Effective date: 20060724 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20100302 |