EP1539807A4 - Therapeutic polypeptides, nucleic acids encoding same, and methods of use - Google Patents

Therapeutic polypeptides, nucleic acids encoding same, and methods of use

Info

Publication number
EP1539807A4
EP1539807A4 EP03785086A EP03785086A EP1539807A4 EP 1539807 A4 EP1539807 A4 EP 1539807A4 EP 03785086 A EP03785086 A EP 03785086A EP 03785086 A EP03785086 A EP 03785086A EP 1539807 A4 EP1539807 A4 EP 1539807A4
Authority
EP
European Patent Office
Prior art keywords
methods
nucleic acids
acids encoding
encoding same
therapeutic polypeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03785086A
Other languages
German (de)
French (fr)
Other versions
EP1539807A2 (en
Inventor
Mei Zhong
Weizhen Ji
Xiaojia Guo
Daniel K Rieger
Muralidhara Padigaru
Rachel Malcolm
Kimberly A Spytek
David W Anderson
Linda Gorman
Elina Catterton
John R Macdougall
David J Stone
Shlomit R Edinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CuraGen Corp
Original Assignee
CuraGen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/236,392 external-priority patent/US20040067490A1/en
Priority claimed from US10/242,943 external-priority patent/US20030087412A1/en
Priority claimed from US10/635,149 external-priority patent/US20050049192A1/en
Application filed by CuraGen Corp filed Critical CuraGen Corp
Publication of EP1539807A2 publication Critical patent/EP1539807A2/en
Publication of EP1539807A4 publication Critical patent/EP1539807A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP03785086A 2002-08-07 2003-08-07 Therapeutic polypeptides, nucleic acids encoding same, and methods of use Withdrawn EP1539807A4 (en)

Applications Claiming Priority (25)

Application Number Priority Date Filing Date Title
US40159702P 2002-08-07 2002-08-07
US401597P 2002-08-07
US40220902P 2002-08-09 2002-08-09
US40220502P 2002-08-09 2002-08-09
US402209P 2002-08-09
US402205P 2002-08-09
US40354802P 2002-08-13 2002-08-13
US40351702P 2002-08-13 2002-08-13
US403517P 2002-08-13
US403548P 2002-08-13
US40369602P 2002-08-15 2002-08-15
US403696P 2002-08-15
US40631802P 2002-08-26 2002-08-26
US406318P 2002-08-26
US40620202P 2002-08-27 2002-08-27
US406202P 2002-08-27
US236392 2002-09-06
US10/236,392 US20040067490A1 (en) 2001-09-07 2002-09-06 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
US10/242,943 US20030087412A1 (en) 1998-10-06 2002-09-13 Nlk1 protein and Nlk1 protein complexes
US242943 2002-09-13
US42313802P 2002-11-01 2002-11-01
US423138P 2002-11-01
US635149 2003-08-06
US10/635,149 US20050049192A1 (en) 1999-06-03 2003-08-06 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
PCT/US2003/024931 WO2004015079A2 (en) 2002-08-07 2003-08-07 Therapeutic polypeptides, nucleic acids encoding same, and methods of use

Publications (2)

Publication Number Publication Date
EP1539807A2 EP1539807A2 (en) 2005-06-15
EP1539807A4 true EP1539807A4 (en) 2006-09-06

Family

ID=31722010

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03785086A Withdrawn EP1539807A4 (en) 2002-08-07 2003-08-07 Therapeutic polypeptides, nucleic acids encoding same, and methods of use

Country Status (5)

Country Link
EP (1) EP1539807A4 (en)
JP (1) JP2006515753A (en)
AU (1) AU2003259704A1 (en)
CA (1) CA2495563A1 (en)
WO (1) WO2004015079A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4863452B2 (en) * 2006-03-30 2012-01-25 国立大学法人 千葉大学 Human Th1 / Th2 differentiation induction system and use thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001053486A1 (en) * 1999-03-08 2001-07-26 Genentech, Inc. Compositions and methods for the treatment of tumor
WO2001064885A1 (en) * 2000-03-02 2001-09-07 Amgen, Inc. Chordin-like-2 molecules and uses thereof
WO2002054940A2 (en) * 2001-01-12 2002-07-18 University Of Medicine & Dentistry Of New Jersey Bone morphogenetic protein-2 in the treatment and diagnosis of cancer
US20030134790A1 (en) * 2002-01-11 2003-07-17 University Of Medicine And Dentistry Of New Jersey Bone Morphogenetic Protein-2 And Bone Morphogenetic Protein-4 In The Treatment And Diagnosis Of Cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846770A (en) * 1994-11-22 1998-12-08 Genetics Institute, Inc. DNA molecules encoding human chordin

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001053486A1 (en) * 1999-03-08 2001-07-26 Genentech, Inc. Compositions and methods for the treatment of tumor
WO2001064885A1 (en) * 2000-03-02 2001-09-07 Amgen, Inc. Chordin-like-2 molecules and uses thereof
WO2002054940A2 (en) * 2001-01-12 2002-07-18 University Of Medicine & Dentistry Of New Jersey Bone morphogenetic protein-2 in the treatment and diagnosis of cancer
US20030134790A1 (en) * 2002-01-11 2003-07-17 University Of Medicine And Dentistry Of New Jersey Bone Morphogenetic Protein-2 And Bone Morphogenetic Protein-4 In The Treatment And Diagnosis Of Cancer

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE Geneseq [online] 12 February 2004 (2004-02-12), "Human chordin protein.", retrieved from EBI accession no. GSP:ABW01852 Database accession no. ABW01852 *
DATABASE Geneseq [online] 15 January 2002 (2002-01-15), "Human chordin protein.", retrieved from EBI accession no. GSP:AAE12889 Database accession no. AAE12889 *
DATABASE Geneseq [online] 15 July 2002 (2002-07-15), "Human PRO243 polypeptide.", XP002379180, retrieved from EBI accession no. GSP:AAU86132 Database accession no. AAU86132 *
DATABASE Geneseq [online] 21 October 2002 (2002-10-21), "Human chordin (CHRD) protein.", retrieved from EBI accession no. GSP:ABG31265 Database accession no. ABG31265 *
DATABASE UniProt [online] 1 March 2001 (2001-03-01), "Chordin precursor.", retrieved from EBI accession no. UNIPROT:CHRD_HUMAN Database accession no. CHRD_HUMAN *
MILLET CAROLINE ET AL: "The human chordin gene encodes several differentially expressed spliced variants with distinct BMP opposing activities", MECHANISMS OF DEVELOPMENT, vol. 106, no. 1-2, August 2001 (2001-08-01), pages 85 - 96, XP002371537, ISSN: 0925-4773 *

Also Published As

Publication number Publication date
WO2004015079A3 (en) 2004-09-02
AU2003259704A1 (en) 2004-02-25
WO2004015079A2 (en) 2004-02-19
CA2495563A1 (en) 2004-02-19
JP2006515753A (en) 2006-06-08
EP1539807A2 (en) 2005-06-15

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