EP1539117A4 - Formulierungen aus fenofibrat und/oder fenofibrat-derivaten mit verbesserter bioverf gbarkeit - Google Patents

Formulierungen aus fenofibrat und/oder fenofibrat-derivaten mit verbesserter bioverf gbarkeit

Info

Publication number
EP1539117A4
EP1539117A4 EP02801215A EP02801215A EP1539117A4 EP 1539117 A4 EP1539117 A4 EP 1539117A4 EP 02801215 A EP02801215 A EP 02801215A EP 02801215 A EP02801215 A EP 02801215A EP 1539117 A4 EP1539117 A4 EP 1539117A4
Authority
EP
European Patent Office
Prior art keywords
fenofibrate
formulations
derivatives
oral bioavailability
improved oral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02801215A
Other languages
English (en)
French (fr)
Other versions
EP1539117A1 (de
Inventor
Amir H Shojaei
Scott A Ibrahim
Beth A Burnside
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shire Laboratories Inc
Original Assignee
Shire Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Laboratories Inc filed Critical Shire Laboratories Inc
Publication of EP1539117A1 publication Critical patent/EP1539117A1/de
Publication of EP1539117A4 publication Critical patent/EP1539117A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP02801215A 2002-06-28 2002-12-20 Formulierungen aus fenofibrat und/oder fenofibrat-derivaten mit verbesserter bioverf gbarkeit Withdrawn EP1539117A4 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39280602P 2002-06-28 2002-06-28
US39279102P 2002-06-28 2002-06-28
US392791P 2002-06-28
US392806P 2002-06-28
PCT/US2002/041093 WO2004002458A1 (en) 2002-06-28 2002-12-20 Formulations of fenofibrate and/or fenofibrate derivatives with improved oral bioavailability

Publications (2)

Publication Number Publication Date
EP1539117A1 EP1539117A1 (de) 2005-06-15
EP1539117A4 true EP1539117A4 (de) 2005-12-14

Family

ID=30003278

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02801215A Withdrawn EP1539117A4 (de) 2002-06-28 2002-12-20 Formulierungen aus fenofibrat und/oder fenofibrat-derivaten mit verbesserter bioverf gbarkeit

Country Status (2)

Country Link
EP (1) EP1539117A4 (de)
WO (1) WO2004002458A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007130713A1 (en) * 2006-02-01 2007-11-15 Transform Pharmaceuticals, Inc. Novel fenofibrate formulations and related methods of treatment
US7772277B2 (en) 2005-08-04 2010-08-10 Transform Pharmaceuticals, Inc. Formulations comprising fenofibrate and a statin, and related methods of treatment
WO2010082214A2 (en) * 2008-07-03 2010-07-22 Panacea Biotec Limited Fenofibrate formulation with enhanced oral bioavailability
WO2013059664A1 (en) * 2011-10-21 2013-04-25 Seachaid Pharmaceuticals, Inc. Pharmaceutical compositions and uses thereof
EP3046551B1 (de) 2013-09-18 2020-08-05 Georgetown University Behandlung von neurodegenerativer erkrankung mit fenofibrate und analoga davon

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6074670A (en) * 1997-01-17 2000-06-13 Laboratoires Fournier, S.A. Fenofibrate pharmaceutical composition having high bioavailability and method for preparing it

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1809499A (en) * 1997-12-10 1999-06-28 Awadhesh K. Mishra Self-emulsifying fenofibrate formulations
ATE497384T1 (de) * 1997-12-10 2011-02-15 Cyclosporine Therapeutics Ltd Omega-3 fettsäure enthaltende pharmazeutische zusammensetzungen
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6074670A (en) * 1997-01-17 2000-06-13 Laboratoires Fournier, S.A. Fenofibrate pharmaceutical composition having high bioavailability and method for preparing it

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
See also references of WO2004002458A1 *
SHEU ET AL: "Characterization and dissolution of fenofibrate solid dispersion systems", INTERNATIONAL JOURNAL OF PHARMACEUTICS, AMSTERDAM, NL, vol. 103, no. 2, 1994, pages 137 - 146, XP002091325, ISSN: 0378-5173 *
TEMELJOTOV ET AL: "Solubilization and dissolution enhancement for sparingly soluble fenofibrate", ACTA PHARMACEUTICA, ZAGREB, HR, vol. 46, no. 2, 1996, pages 131 - 136, XP002104609, ISSN: 1330-0075 *

Also Published As

Publication number Publication date
EP1539117A1 (de) 2005-06-15
WO2004002458A1 (en) 2004-01-08

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20050125

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A4 Supplementary search report drawn up and despatched

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