EP1538989B1 - Appareil permettant de fermer des perforations dans des vaisseaux sanguins - Google Patents
Appareil permettant de fermer des perforations dans des vaisseaux sanguins Download PDFInfo
- Publication number
- EP1538989B1 EP1538989B1 EP03766304A EP03766304A EP1538989B1 EP 1538989 B1 EP1538989 B1 EP 1538989B1 EP 03766304 A EP03766304 A EP 03766304A EP 03766304 A EP03766304 A EP 03766304A EP 1538989 B1 EP1538989 B1 EP 1538989B1
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- EP
- European Patent Office
- Prior art keywords
- bar
- filament
- eyelet
- bore
- distal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000007789 sealing Methods 0.000 title claims abstract description 32
- 210000004204 blood vessel Anatomy 0.000 title abstract description 7
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12009—Implements for ligaturing other than by clamps or clips, e.g. using a loop with a slip knot
- A61B17/12013—Implements for ligaturing other than by clamps or clips, e.g. using a loop with a slip knot for use in minimally invasive surgery, e.g. endoscopic surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00349—Needle-like instruments having hook or barb-like gripping means, e.g. for grasping suture or tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00637—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for sealing trocar wounds through abdominal wall
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00646—Type of implements
- A61B2017/00659—Type of implements located only on one side of the opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00672—Locating means therefor, e.g. bleed back lumen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0406—Pledgets
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B2017/0496—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials for tensioning sutures
Definitions
- the present invention relates to apparatus for sealing punctures in blood vessels. More specifically, the invention relates to one or more devices that may be deployed in tissue distal of a vessel having a puncture to apply an internal compressive force upon the vessel to facilitate sealing of the puncture.
- a large number of medical diagnostic and therapeutic procedures involve the percutaneous introduction of instrumentation into the blood vessel.
- coronary angioplasty, angiography, atherectomy, stenting, and numerous other procedures often involve accessing the vasculature through placement of a catheter or other device in a patient's femoral artery or other blood vessel. Once the procedure is completed and the catheter or other diagnostic or therapeutic device is removed, bleeding from the resultant vascular puncture must be stopped.
- Another traditional approach to subcutaneous puncture closure comprises having a medical practitioner internally suture the vessel puncture. This method, however, often requires a complex procedure and requires considerable skill by the medical practitioner.
- Apparatus and methods also are known in which a plug is introduced into the vessel puncture to cover the puncture and promote hemostasis.
- a plug is described in U.S. Patent No. 5,061,274 to Kensey and comprises a plug made from animal-derived collagen.
- Such apparatus may be unsuitable for some patients due to an adverse immunological reaction to animal-derived collagen.
- a plug inserted into the puncture tract may be dislodged into the vessel during the healing process due to the application of pressure to the wound, potentially causing stenosis of the vessel.
- U.S. Patent Nos. 5,411,520 and 5,810,884 disclose further examples of an apparatus and method in which a plug member is introduced into the puncture site to promote hemostasis.
- an anchor member is designed to be secured inside the blood vessel.
- a cable attached to a buttressing support member outside of the blood vessel is used to secure the plug member in position.
- the present invention provides an apparatus as defined in claim 1 or claim 15. Preferred features of the invention are recited in the dependent claims.
- the invention provides an apparatus for sealing a puncture within a vessel that comprises at least one device that may be deployed in tissue distal of the vessel to apply an internal compressive force upon the vessel.
- internal compressive force refers generally to a force imposed at a location distal of a vessel and occurring in proximal direction toward a skin puncture.
- an “external compressive force” is defined herein as a force imposed at a location near a skin puncture and occurring in a distal direction toward the vessel.
- the device preferably comprises a bar having a bore and a filament disposed through the bore.
- the bar and the filament are provided in a contracted state within a delivery sheath, for example, a hypodermic needle, having proximal and distal ends and a sharpened tip at the distal end.
- the tip of the delivery sheath is advanced distally to pass through the original puncture, which had previously been formed in a proximal lateral surface of the vessel.
- the tip further is advanced to pierce through a distal lateral surface of the vessel and is positioned distal of the vessel.
- the bar then is ejected from within the confines of the delivery sheath, e. g. by advancing a push rod, to cause the bar to deploy distal of the vessel.
- First and second ends of the filament then may be retracted proximally from outside of a patient's body to retract the bar against the distal lateral surface of the vessel and apply an internal compressive force thereto.
- the internal compressive force causes coagulation within the punctures that facilitates sealing of the proximal and distal punctures.
- the first end of the filament may be retracted to cause the second end to be pulled through the bore of the bar and from within the patient's body.
- the bar which preferably is biodegradable, remains in the patient's body after the filament is removed.
- the first and second ends of the filament may be tensioned within a tensioning device disposed on an exterior surface of a patient's skin.
- the use of the tensioning device advantageously permits a physician to retract the first and second ends of the filament to apply the internal compressive force via the bar, then lock the filament within the tensioning device so that the physician need not manually retain the compressive force upon the vessel.
- the tensioning device serves to apply an external compressive force to the skin to enhance compression of the vessel.
- FIGS. 1A-1D are, respectively, a side view of a first puncture sealing device, side views of alternative puncture sealing devices, and a perspective view of an alternative puncture sealing device provided in accordance with a first embodiment of the present invention
- FIGS. 2A-2B are, respectively, a side view and a side sectional view of apparatus for delivering the puncture sealing device of FIG. 1A ;
- FIGS. 3A-3F are side sectional views illustrating an exemplary method of using the apparatus of FIGS. 2 ;
- puncture sealing device 20 comprises cylindrically-shaped bar 22 having proximal and distal ends and bore 24 extending laterally through a central region of bar 22.
- Bar 22 alternatively may comprise a rectangular or any other cross-section.
- Filament 26, having first end 27 and second end 28, extends through bore 24 and may be used to manipulate the positioning of bar 22, as described hereinbelow.
- bar 22 comprises a biocompatible plastic or metal alloy, or a biodegradable material such as polyglycolic acid.
- Filament 26 may comprise a biocompatible wire, or more preferably a conventional suture material, for example, a biodegradable suture material.
- alternative puncture sealing device 20' preferably is provided in accordance with bar 22 of FIG. 1A with the exception that bar 22' preferably is solid and comprises first eyelet 23 coupled to a central region of bar 22', e.g., using a solder or weld. Filament 26' extends through first eyelet 23 and may be used to manipulate the positioning of bar 22', as described hereinbelow.
- alternative puncture sealing device 20" preferably is provided in accordance with bar 22 of FIG. 1A with the exception that bar 22" comprises central bore 25 extending laterally through a central region of bar 22" and further comprises end eyelet 29 coupled to the distal end of bar 22".
- Filament 26" preferably extends through central bore 25, then through end eyelet 29, and optionally also may extend back through central bore 25 after passing through eyelet 29, as shown in FIG. 1C .
- filament 26" may just extend once through central bore 25 and then through end eyelet 29.
- bar 22" alternatively may be provided with a central eyelet and an end bore, with central and end eyelets, or with central and end bores.
- alternative puncture sealing device 30 is illustrated as comprising substantially flat member 32 having an oval-shaped configuration.
- Member 32 comprises bore 34 extending through protruding region 33, which preferably is provided in a central region of member 32, as shown in FIG. 1B .
- Filament 36 having first end 37 and second end 38 extends through bore 34 to perform the functions described hereinbelow. It will be apparent to those skilled in the art that while bars 22 and member 32 of FIGS. 1A-1D are illustratively shown having cylindrical and oval-shaped configurations, respectively, other configurations advantageously may be provided to perform the functions described hereinbelow.
- puncture sealing apparatus 40 of the first embodiment of the present invention preferably comprises delivery sheath 42 having proximal and distal ends and lumen 43 extending therebetween.
- the proximal end of delivery sheath 42 preferably comprises optional handle 41 that is configured to be grasped by a physician.
- Distal end 48 of delivery sheath 42 comprises sharpened tip 45 and opening 47, which is in fluid communication with lumen 43, as shown in FIG. 2B .
- Distal end 48 may comprise, for example, a standard hypodermic needle attached to handle 41.
- Distal end 48 preferably comprises a significantly smaller cross sectional area than optional handle 41 of delivery sheath 42.
- Bar 22 and filament 26 of FIG. 1A preferably are used in conjunction with delivery sheath 42, as described hereinbelow.
- Apparatus 40 preferably further comprises push rod 44 having proximal and distal ends.
- Delivery sheath 42 is sized so that bar 22, push rod 44, and first and second ends 27 and 28 of filament 26 may be provided in a contracted state within lumen 43. In the contracted state, the distal end of push rod 44 is disposed just proximal of bar 22.
- proximal puncture 74 has been formed in proximal lateral surface 84 of vessel V , which is situated within tissue T.
- Puncture tract 70 has been formed and permits fluid communication between an exterior surface of a patient's body and lumen 72 of vessel V. Puncture tract 70 may have been formed, for example, as a means for introducing a guidewire and/or catheter into vessel V to perform a variety of medical procedures.
- Sharpened tip 45 at the distal end of delivery sheath 42 is inserted into a patient's body, preferably via preexisting puncture tract 70 of FIG. 3A .
- sharpened tip 45 is inserted through skin S, tissue T, proximal puncture 74, and through lumen 72 of vessel V.
- apparatus 40 optionally may be delivered through an external sheath, such as an introducer or guiding catheter.
- Sharpened tip 45 further is advanced distally through lumen 72 to pierce through a distal wall of vessel V, such that sharpened tip 45 is again disposed within tissue T distal of vessel V, as shown in FIG. 3B .
- the piercing of the distal wall of vessel V forms distal puncture 75 in distal lateral surface 85 of vessel V, which is substantially diametrically opposing proximal puncture 74 in proximal lateral surface 84.
- Distal puncture 75 preferably is significantly smaller than proximal puncture 74, for example, twice as small to an order of magnitude or more smaller in cross-sectional diameter.
- the proximal end of push rod 44 is advanced distally by a physician to cause the distal end of push rod 44 to abut the proximal end of bar 22.
- Push rod 44 is advanced distally until bar 22 is disposed distal of opening 47. Delivery sheath 42 and push rod 44 then may be retracted proximally and removed from the patient's body.
- filament 26 may be pulled slightly proximally to cause bar 22 to assume an orientation that is substantially parallel to a longitudinal axis of vessel V, as shown in FIG. 3D .
- central bore 25 and end eyelet 29 may be utilized to assist in urging bar 22" to an orientation that is substantially parallel to the vessel when either or both ends of filament 26" are retracted.
- first and second ends 27 and 28 of filament 26 are retracted further proximally to retract bar 22 toward distal lateral surface 85 of vessel V.
- tensioning device 90 preferably is used in conjunction with apparatus 40 of the present invention.
- Tensioning device 90 is similar in structure to a tensioning device previously commercially marketed under the trade name "BioDISC” by BioInterventional Corp. of Pleasanton, CA.
- Tensioning device 90 comprises upright 91 having legs 92 and grip 94.
- Grip 94 may comprise a V-shaped groove in an elastomeric block and retains tension on filament 26 when ends 27 and 28 are pulled distally.
- Legs 92 of tensioning device 90 are placed atop an exterior surface of skin S so that space 93, formed between legs 92, is positioned substantially over skin puncture 76.
- First and second ends 27 and 28 of filament 26 are engaged in grip 94, and may be retracted proximally while legs 92 maintain contact with skin S , as shown in FIG. 3E .
- the retraction of filament 26 causes bar 22 to provide an internal compressive force upon distal lateral surface 85 of vessel V, while legs 92 provide an external compressive force upon proximal lateral surface 84 through tissue T during tensioning of filament 26.
- grip 94 retains ends 27 and 28 in a tensioned state.
- this permits the internal and external compressive forces described hereinabove to be applied to vessel V without requiring a physician to manually hold ends 27 and 28 of filament 26 for an extended period of time.
- the compressive forces imposed upon vessel V cause lumen 72 to narrow locally, which in turn causes coagulation of blood in the vicinity of punctures 74 and 75. Over a period of time, the coagulation occurring within punctures 74 and 75 results in a reduction in diameter of the punctures and halts blood loss from the vessel.
- the use of bar 22 in conjunction with tensioning device 90 allows compressive forces to be applied to vessel V from substantially diametrically opposing surfaces of vessel V to facilitate closure of punctures 74 and 75.
- filament ends 27 and 28 may be intermittently disengaged from grip 94 throughout the procedure to relieve the tensile force imposed upon filament 26 to temporarily reduce the compressive forces applied to vessel V.
- collagen or a biocompatible gel or polymer such as a water swellable gel or a biodegradable polymer like Polyethylene Glycol (“PEG”), may be injected into puncture tract 70 to reduce a diameter of the puncture tract either before, during or after the time in which the internal compressive force is applied to distal lateral surface 85.
- PEG Polyethylene Glycol
- the agent is injected into puncture tract 70 while filament 26 is tensioned within tensioning device 90.
- the compressive forces applied to vessel V have caused a significant reduction in the diameter of punctures 74 and 75 to effectively seal the punctures.
- Filament 26 then may be released from grip 94 to relieve the tensile forces imposed upon filament 26.
- a physician may proximally retract first end 27 of filament 26 to cause second end 28 to be pulled in a distal direction through skin puncture 76, proximal and distal punctures 74 and 75, and through bore 24 of bar 22.
- First end 27 further is retracted proximally to remove second end 28 from the patient's body, thereby leaving bar 22 disposed within tissue T.
- bar 22 is manufactured from a biocompatible material such as polyglycolic acid, it will be resorbed by the patient's body.
- sharpened tip 45 of sheath 42 may initially pierce substantially deeper into tissue T, i.e., to a location substantially distal of distal lateral surface 85 of vessel V. Accordingly, when bar 22 is ejected from sheath 42, bar 22 is disposed at a location within tissue T that is not in close proximity to distal lateral surface 85.
- filament 26 when filament 26 is placed in tension, tissue T, as opposed to bar 22 directly, applies the internal compressive force upon distal lateral surface 85.
- This approach advantageously may reduce trauma to distal lateral surface 85 of vessel V when compressive forces are imposed as described hereinabove.
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Claims (22)
- Appareil destiné à faciliter la fermeture d'une ponction (74) formée dans une surface latérale proximale (84) d'un vaisseau (V) dans le corps d'un patient, l'appareil comprenant :une barre (22, 22") ayant des extrémités proximale et distale et un premier alésage (24, 25) s'étendant latéralement à travers celle-ci ; etun filament (26, 26") ayant une première extrémité (27, 27") et une deuxième extrémité (28, 28"), le filament (26, 26") disposé dans l'alésage (24, 25) de telle manière que les première et deuxième extrémités (27, 27" ; 28, 28") s'étendent dans la même direction relativement au dit alésage (24, 25)la barre (22, 22") étant configurée pour appliquer une force de compression sur une surface latérale distale (85) d'un vaisseau (V),
caractérisé en ce que le filament (26, 26") est adapté pour se déplacer librement dans le premier alésage (24, 25) et en ce que la première extrémité proximale (27, 27") du filament (26, 26") est adaptée pour être rétractée et entraîner la traction de la deuxième extrémité (28, 28") du filament dans le premier alésage (24, 25) de la barre (22, 22") et de l'intérieur du corps du patient. - Appareil selon la revendication 1, qui comprend en outre une gaine de délivrance (42) ayant des extrémités proximale et distale, une lumière (43) s'étendant entre celles-ci et une extrémité affûtée (45) au niveau de l'extrémité distale, la lumière (43) étant configurée pour contenir la barre (22, 22") et le filament (26, 26").
- Appareil selon la revendication 2, qui comprend en outre une tige poussoir (44) disposée dans la lumière (43) proximale de la barre (22, 22").
- Appareil selon la revendication 1, 2 ou 3 dans lequel la barre (22, 22") a une forme choisie dans le groupe constitué par les formes cylindriques, les formes rectangulaires, et les formes ovales.
- Appareil selon la revendication 1, 2, 3 ou 4, dans lequel la barre (22, 22") comprend un matériau biodégradable.
- Appareil selon la revendication 1, 2, 3, 4 ou 5, qui comprend en outre un dispositif de mise en tension (90) configuré pour maintenir le filament (26, 26") dans un état de tension.
- Appareil selon la revendication 6, dans lequel le dispositif de mise en tension (90) comprend :un montant (91) ayant des extrémités supérieure et inférieure ;une pluralité de pattes (92) fixées à l'extrémité inférieure ; etun point de préhension (94) fixé à l'extrémité supérieure.
- Appareil selon la revendication 7, dans lequel le point de préhension (94) comprend un sillon en forme de V formé dans un matériau élastomère.
- Appareil selon l'une quelconque des revendications 1 à 8, dans lequel le premier alésage (24, 25) est disposé dans une région centrale de la barre (22, 22").
- Appareil selon l'une quelconque des revendications 1 à 9, qui comprend en outre un oeillet (29) couplé à la barre (22"), le filament (26") étant disposé à la fois dans le premier alésage et dans l'oeillet (23).
- Appareil selon la revendication 10, dans lequel le premier alésage (25) est disposé dans une région centrale de la barre (22"), et l'oeillet (29) est couplé à une région distale de la barre.
- Appareil selon la revendication 10 ou 11, qui comprend en outre un oeillet (23) couplé à la barre, l'oeillet (23) étant couplé à une région centrale de la barre et le premier alésage (24, 25) étant disposé dans une région distale de la barre.
- Appareil selon l'une quelconque des revendications 1 à 12, qui comprend en outre un deuxième alésage s'étendant latéralement dans la barre, le filament étant disposé à la fois dans le premier alésage et dans le deuxième alésage.
- Appareil selon la revendication 13, dans lequel le premier alésage (24, 25) est disposé dans une région centrale de la barre (22, 22"), et le deuxième alésage est disposé dans une région distale de la barre.
- Appareil destiné à faciliter la fermeture d'une ponction (74) formée dans une surface latérale proximale (84) d'un vaisseau (V) dans le corps d'un patient, l'appareil comprenant :une barre (22', 32) ayant des extrémités proximale et distale et un premier oeillet (23, 33) couplé à la barre (22', 32) ; etun filament (26', 36) ayant une première extrémité (27', 37) et une deuxième extrémité (28', 38), le filament (26', 36) disposé dans le premier oeillet (23, 33) de telle manière que les première et deuxième extrémités (27', 37 ; 28', 38) s'étendent dans la même direction relativement au dit oeillet (23, 33) ;la barre (22', 32) étant configurée pour appliquer une force de compression sur une surface latérale distale (85) d'un vaisseau ;
caractérisé en ce que le filament (26', 36) est adapté pour se déplacer librement dans le premier oeillet (23, 33) et en ce que la première extrémité proximale (27', 37) du filament (26', 36) est adaptée pour être rétractée et entraîner la traction de la deuxième extrémité (28', 38) du filament dans le premier oeillet (23, 33) de la barre (22', 32) et de l'intérieur du corps du patient. - Appareil selon la revendication 15, dans lequel le premier oeillet (23, 33) est couplée à une région centrale de la barre (22', 32).
- Appareil selon la revendication 15 ou 16, dans lequel la barre comprend en outre un deuxième oeillet couplé à la barre (22', 32), le filament étant disposé dans le premier oeillet (23, 33) et dans le deuxième oeillet.
- Appareil selon la revendication 17, dans lequel le premier oeillet (23, 33) est couplé à une région centrale de la barre (22', 32), et le deuxième oeillet est couplé à une région distale de la barre.
- Appareil selon la revendication 15, 16, 17 ou 18 qui comprend en outre une gaine de délivrance (42) ayant des extrémités proximale et distale, une lumière (43) s'étendant entre celles-ci et une extrémité affûtée (45) au niveau de l'extrémité distale, la lumière (43) étant configurée pour contenir la barre (22', 32) et le filament (26', 36).
- Appareil selon la revendication 19, qui comprend en outre une tige poussoir (44) disposée dans la lumière (43) de la gaine de délivrance (42) proximale de la barre (22', 32).
- Appareil selon l'une quelconque des revendications 15 à 20, dans lequel la barre (22', 32) comprend un matériau biodégradable.
- Appareil selon l'une quelconque des revendications 15 à 21, comprenant en outre un dispositif de mise en tension (90) configuré pour maintenir le filament (26', 36) dans un état de tension.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40122202P | 2002-08-01 | 2002-08-01 | |
US401222P | 2002-08-01 | ||
PCT/EP2003/008245 WO2004012601A2 (fr) | 2002-08-01 | 2003-07-25 | Appareil permettant de fermer des perforations dans des vaisseaux sanguins |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1538989A2 EP1538989A2 (fr) | 2005-06-15 |
EP1538989B1 true EP1538989B1 (fr) | 2010-03-17 |
Family
ID=31495941
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP03766304A Expired - Lifetime EP1538989B1 (fr) | 2002-08-01 | 2003-07-25 | Appareil permettant de fermer des perforations dans des vaisseaux sanguins |
Country Status (8)
Country | Link |
---|---|
US (1) | US20060100665A1 (fr) |
EP (1) | EP1538989B1 (fr) |
JP (1) | JP2005534387A (fr) |
AT (1) | ATE460885T1 (fr) |
AU (1) | AU2003260330A1 (fr) |
CA (1) | CA2492702C (fr) |
DE (1) | DE60331740D1 (fr) |
WO (1) | WO2004012601A2 (fr) |
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US8083766B2 (en) | 1999-09-13 | 2011-12-27 | Rex Medical, Lp | Septal defect closure device |
US7942888B2 (en) | 1999-09-13 | 2011-05-17 | Rex Medical, L.P. | Vascular hole closure device |
US7662161B2 (en) | 1999-09-13 | 2010-02-16 | Rex Medical, L.P | Vascular hole closure device |
US7267679B2 (en) | 1999-09-13 | 2007-09-11 | Rex Medical, L.P | Vascular hole closure device |
US7993366B2 (en) * | 2004-05-27 | 2011-08-09 | Cardiva Medical, Inc. | Self-tensioning vascular occlusion device and method for its use |
US9610070B2 (en) | 2007-06-15 | 2017-04-04 | Vivasure Medical Limited | Closure device |
US8906059B2 (en) | 2007-07-13 | 2014-12-09 | Rex Medical, L.P. | Vascular hole closure device |
US8491629B2 (en) | 2008-02-15 | 2013-07-23 | Rex Medical | Vascular hole closure delivery device |
US8920463B2 (en) | 2008-02-15 | 2014-12-30 | Rex Medical, L.P. | Vascular hole closure device |
US8920462B2 (en) | 2008-02-15 | 2014-12-30 | Rex Medical, L.P. | Vascular hole closure device |
US20110029013A1 (en) | 2008-02-15 | 2011-02-03 | Mcguckin James F | Vascular Hole Closure Device |
US8070772B2 (en) | 2008-02-15 | 2011-12-06 | Rex Medical, L.P. | Vascular hole closure device |
US9226738B2 (en) | 2008-02-15 | 2016-01-05 | Rex Medical, L.P. | Vascular hole closure delivery device |
WO2011080588A2 (fr) | 2009-12-30 | 2011-07-07 | Vivasure Medical Limited | Système de fermeture et ses utilisations |
EP2658453B1 (fr) * | 2010-12-30 | 2020-04-29 | Vivasure Medical Limited | Systèmes de fermeture chirurgicale |
US9074411B2 (en) * | 2012-02-20 | 2015-07-07 | James V. Miller | Shutter slat and compact shutter assembly |
WO2013128292A2 (fr) | 2012-02-29 | 2013-09-06 | Vivasure Medical Limited | Systèmes, dispositifs et procédés de fermeture de perforation percutanée |
US9131932B2 (en) * | 2013-02-01 | 2015-09-15 | St. Jude Medical Puerto Rico Llc | Dual lumen carrier tube with retractable sleeve and methods |
US9850013B2 (en) | 2013-03-15 | 2017-12-26 | Vivasure Medical Limited | Loading devices and methods for percutaneous perforation closure systems |
EP3232939B1 (fr) | 2014-12-15 | 2020-09-23 | Vivasure Medical Limited | Élément pouvant être scellé implantable avec une couche à mailles |
EP3232938B1 (fr) | 2014-12-15 | 2024-05-01 | Vivasure Medical Limited | Appareil de fermeture avec élément scellable flexible et élément de support flexible |
EP3389505A1 (fr) | 2015-12-15 | 2018-10-24 | Vivasure Medical Limited | Appareil de fermeture d'artériotomie avec patin rainure pour distribution avantageuse de compression |
CA3120326A1 (fr) * | 2018-12-02 | 2020-06-11 | Empress Medical, Inc. | Passage d'un element de tension autour d'une masse tissulaire |
US11504105B2 (en) | 2019-01-25 | 2022-11-22 | Rex Medical L.P. | Vascular hole closure device |
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US1452338A (en) * | 1922-03-27 | 1923-04-17 | Flowers William James | Rope and cable tie |
US3411505A (en) * | 1965-12-15 | 1968-11-19 | Paul D. Nobis | Device for interrupting arterial flow |
US4929246A (en) * | 1988-10-27 | 1990-05-29 | C. R. Bard, Inc. | Method for closing and sealing an artery after removing a catheter |
US5061274A (en) * | 1989-12-04 | 1991-10-29 | Kensey Nash Corporation | Plug device for sealing openings and method of use |
GB9020379D0 (en) * | 1990-09-18 | 1990-10-31 | Femcare Ltd | Suture apparatus |
US5366480A (en) * | 1990-12-24 | 1994-11-22 | American Cyanamid Company | Synthetic elastomeric buttressing pledget |
US5411520A (en) * | 1991-11-08 | 1995-05-02 | Kensey Nash Corporation | Hemostatic vessel puncture closure system utilizing a plug located within the puncture tract spaced from the vessel, and method of use |
US5814073A (en) * | 1996-12-13 | 1998-09-29 | Bonutti; Peter M. | Method and apparatus for positioning a suture anchor |
US5403348A (en) * | 1993-05-14 | 1995-04-04 | Bonutti; Peter M. | Suture anchor |
US5411420A (en) * | 1993-05-27 | 1995-05-02 | Die Tech, Inc. | Solder terminal strip |
US5545178A (en) * | 1994-04-29 | 1996-08-13 | Kensey Nash Corporation | System for closing a percutaneous puncture formed by a trocar to prevent tissue at the puncture from herniating |
US6071300A (en) * | 1995-09-15 | 2000-06-06 | Sub-Q Inc. | Apparatus and method for percutaneous sealing of blood vessel punctures |
US5718717A (en) * | 1996-08-19 | 1998-02-17 | Bonutti; Peter M. | Suture anchor |
US5810884A (en) * | 1996-09-09 | 1998-09-22 | Beth Israel Deaconess Medical Center | Apparatus and method for closing a vascular perforation after percutaneous puncture of a blood vessel in a living subject |
US6030007A (en) * | 1997-07-07 | 2000-02-29 | Hughes Electronics Corporation | Continually adjustable nonreturn knot |
US6626919B1 (en) * | 1997-12-29 | 2003-09-30 | Lee L. Swanstrom | Method and apparatus for attaching or locking an implant to an anatomic vessel or hollow organ wall |
US6228096B1 (en) * | 1999-03-31 | 2001-05-08 | Sam R. Marchand | Instrument and method for manipulating an operating member coupled to suture material while maintaining tension on the suture material |
FR2798280B1 (fr) * | 1999-09-14 | 2002-04-12 | Medac Pharma S A | Anneau de gastroplastie |
US6506197B1 (en) * | 2000-11-15 | 2003-01-14 | Ethicon, Inc. | Surgical method for affixing a valve to a heart using a looped suture combination |
US6500184B1 (en) * | 2001-01-31 | 2002-12-31 | Yung C. Chan | Suturing apparatus and method of suturing |
US6843799B2 (en) * | 2002-03-25 | 2005-01-18 | Edwin C. Bartlett | Suture anchor system and associated method |
-
2003
- 2003-07-25 EP EP03766304A patent/EP1538989B1/fr not_active Expired - Lifetime
- 2003-07-25 CA CA2492702A patent/CA2492702C/fr not_active Expired - Fee Related
- 2003-07-25 JP JP2004525323A patent/JP2005534387A/ja active Pending
- 2003-07-25 AT AT03766304T patent/ATE460885T1/de not_active IP Right Cessation
- 2003-07-25 DE DE60331740T patent/DE60331740D1/de not_active Expired - Lifetime
- 2003-07-25 AU AU2003260330A patent/AU2003260330A1/en not_active Abandoned
- 2003-07-25 US US10/523,217 patent/US20060100665A1/en not_active Abandoned
- 2003-07-25 WO PCT/EP2003/008245 patent/WO2004012601A2/fr active Application Filing
Also Published As
Publication number | Publication date |
---|---|
CA2492702C (fr) | 2011-11-22 |
DE60331740D1 (de) | 2010-04-29 |
EP1538989A2 (fr) | 2005-06-15 |
WO2004012601A2 (fr) | 2004-02-12 |
CA2492702A1 (fr) | 2004-02-12 |
JP2005534387A (ja) | 2005-11-17 |
AU2003260330A1 (en) | 2004-02-23 |
ATE460885T1 (de) | 2010-04-15 |
US20060100665A1 (en) | 2006-05-11 |
WO2004012601A3 (fr) | 2004-04-15 |
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