EP1497423A4 - Mcp-1 mutant proteins, antibodies, compositions, methods and uses - Google Patents

Mcp-1 mutant proteins, antibodies, compositions, methods and uses

Info

Publication number
EP1497423A4
EP1497423A4 EP03721448A EP03721448A EP1497423A4 EP 1497423 A4 EP1497423 A4 EP 1497423A4 EP 03721448 A EP03721448 A EP 03721448A EP 03721448 A EP03721448 A EP 03721448A EP 1497423 A4 EP1497423 A4 EP 1497423A4
Authority
EP
European Patent Office
Prior art keywords
mcp
antibodies
compositions
methods
mutant proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03721448A
Other languages
German (de)
French (fr)
Other versions
EP1497423A2 (en
Inventor
George A Heavner
Anuk Das
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Biotech Inc
Original Assignee
Centocor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Inc filed Critical Centocor Inc
Publication of EP1497423A2 publication Critical patent/EP1497423A2/en
Publication of EP1497423A4 publication Critical patent/EP1497423A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
EP03721448A 2002-03-26 2003-03-24 Mcp-1 mutant proteins, antibodies, compositions, methods and uses Withdrawn EP1497423A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36793202P 2002-03-26 2002-03-26
US367932P 2002-03-26
PCT/US2003/009056 WO2003083059A2 (en) 2002-03-26 2003-03-24 Mcp-1 mutant proteins, antibodies, compositions, methods and uses

Publications (2)

Publication Number Publication Date
EP1497423A2 EP1497423A2 (en) 2005-01-19
EP1497423A4 true EP1497423A4 (en) 2006-05-24

Family

ID=28675424

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03721448A Withdrawn EP1497423A4 (en) 2002-03-26 2003-03-24 Mcp-1 mutant proteins, antibodies, compositions, methods and uses

Country Status (3)

Country Link
EP (1) EP1497423A4 (en)
AU (1) AU2003224761A1 (en)
WO (1) WO2003083059A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR046594A1 (en) 2003-10-16 2005-12-14 Applied Research Systems THERAPEUTIC USES OF CHEMOQUINE VARIANTS
EP1926747A1 (en) 2005-08-12 2008-06-04 Schering Corporation Mcp1 fusions
US8524217B2 (en) 2010-05-11 2013-09-03 Merck Sharp & Dohme Corp. MCP1-Ig fusion variants

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5413778A (en) * 1992-10-05 1995-05-09 The Regents Of The University Of Michigan Labelled monocyte chemoattractant protein material and medical uses thereof
US6174995B1 (en) * 1994-08-23 2001-01-16 Haodong Li Human chemokines, CKβ4 and CKβ10/MCP-4
US5688927A (en) * 1995-06-07 1997-11-18 Icos Corporation Macrophage derived chemokine
US6383782B1 (en) * 1997-07-25 2002-05-07 Zeneca Limited MCP-1 analogs

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JARNAGIN KURT ET AL: "Identification of surface residues of the monocyte chemotactic protein 1 that affect signaling through the receptor CCR2", BIOCHEMISTRY, vol. 38, no. 49, 7 December 1999 (1999-12-07), pages 16167 - 16177, XP002336958, ISSN: 0006-2960 *
KRUSZYNSKI MARIAN ET AL: "Synthesis and biological characterization of human monocyte chemoattractant protein 1 (MCP-1) and its analogs", JOURNAL OF PEPTIDE SCIENCE, vol. 12, no. 1, January 2006 (2006-01-01), pages 25 - 32, XP002373882, ISSN: 1075-2617 *

Also Published As

Publication number Publication date
WO2003083059A2 (en) 2003-10-09
AU2003224761A8 (en) 2003-10-13
WO2003083059A3 (en) 2004-10-07
EP1497423A2 (en) 2005-01-19
AU2003224761A1 (en) 2003-10-13

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20060411

17Q First examination report despatched

Effective date: 20080421

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Effective date: 20081104