EP1378663A2 - Peristaltic pump - Google Patents

Peristaltic pump Download PDF

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Publication number
EP1378663A2
EP1378663A2 EP03014680A EP03014680A EP1378663A2 EP 1378663 A2 EP1378663 A2 EP 1378663A2 EP 03014680 A EP03014680 A EP 03014680A EP 03014680 A EP03014680 A EP 03014680A EP 1378663 A2 EP1378663 A2 EP 1378663A2
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EP
European Patent Office
Prior art keywords
pump
sealing membrane
hose
peristaltic
connecting rod
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP03014680A
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German (de)
French (fr)
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EP1378663A3 (en
EP1378663B1 (en
Inventor
Dieter Herwig
Reinhard Knuth
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B Braun Melsungen AG
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B Braun Melsungen AG
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Publication of EP1378663A2 publication Critical patent/EP1378663A2/en
Publication of EP1378663A3 publication Critical patent/EP1378663A3/en
Application granted granted Critical
Publication of EP1378663B1 publication Critical patent/EP1378663B1/en
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Expired - Lifetime legal-status Critical Current

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    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/08—Machines, pumps, or pumping installations having flexible working members having tubular flexible members
    • F04B43/082—Machines, pumps, or pumping installations having flexible working members having tubular flexible members the tubular flexible member being pressed against a wall by a number of elements, each having an alternating movement in a direction perpendicular to the axes of the tubular member and each having its own driving mechanism

Definitions

  • the sealing membrane does not span the pump fingers, there is no constant periodic expansion of the sealing membrane between adjacent pump fingers. This will make less Drive energy needed. The forces still needed, the The restoring forces do not have to deform the membrane of the pump hose are applied, but are by provided the pump drive. This makes the delivery rate accuracy improved over longer infusion times. Moreover the wear of the sealing membrane is reduced.
  • the usage of connecting rods enables simple and small Passage through the sealing membrane.
  • the sealing membrane should do not form a stretched surface, but a loose fold membrane that adapts to the movements of the connecting rods without that significant material stresses occur.
  • a special embodiment is constructed so that the eccentric discs the shaft are integrally formed.
  • the wave thus forms a crankshaft, so to speak.
  • the outer coat the eccentric disc can be shaped so that it is simultaneously forms the inner raceway of a ball bearing.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Reciprocating Pumps (AREA)

Abstract

The peristaltic tube pump has a shaft (20) with eccentric discs (21) each having a bearing and each moving a pump finger, and a sealing membrane (27) between the shaft and pump. Each bearing has a connecting rod (25) engaging with a linearly guided pump finger, with the pump fingers being located on the sealing membrane side facing the tube pump, and with the connecting rods passing through the sealing membrane. The sealing membrane has side folds which allow it to adapt to the transverse movement of the connecting rod.

Description

Die Erfindung betrifft eine peristaltische Schlauchpumpe mit einer Welle, die mehrere Exzenterscheiben aufweist, von denen jede ein Lager trägt und damit einen Pumpenfinger quer zu einem Pumpenschlauch bewegt, und mit einer zwischen der Welle und dem Pumpenschlauch angeordneten Dichtmembran.The invention relates to a peristaltic peristaltic pump a shaft that has several eccentric discs, one of which each carries a bearing and thus a pump finger across one Pump hose moves, and with one between the shaft and the Pump hose arranged sealing membrane.

Peristaltische Schlauchpumpen werden häufig als Infusions- oder Transfusionspumpen zur Förderung flüssiger Substanzen im medizinischen Bereich eingesetzt. Bekannt sind lineare Schlauchpumpen, bei denen ein gerader Pumpenschlauch von zahlreichen Pumpenfingern fortlaufend und zyklisch gegen ein Widerlager gedrückt wird, so dass die Flüssigkeit in dem Pumpenschlauch in Förderrichtung bewegt wird. EP 0 214 443 A1 beschreibt eine peristaltische lineare Schlauchpumpe mit zahlreichen an einer Welle befestigten Exzenterscheiben. Jede Exzenterscheibe trägt ein Kugellager und wirkt auf einen linear bewegbaren Pumpenfinger. Sämtliche Pumpenfinger werden von einer Dichtmembran überspannt, die eine abdichtende Trennung zwischen dem Antriebsmechanismus und dem Pumpenschlauch bildet. Dadurch werden Beschädigungen und Verschmutzungen des Pumpenschlauchs vermieden. Andererseits wird das Innere der Pumpe gegen eindringende Flüssigkeit geschützt. Eine so angeordnete Dichtmembran beeinflusst die Fördergenauigkeit negativ. Sie bewirkt eine Kraftkopplung zwischen benachbarten Pumpenfingern, wodurch auch der elektrische Energieverbrauch erhöht wird. Ein Teil der Rückstellkräfte des Pumpenschlauches wird bei dieser Membrananordnung benötigt, um die Dichtmembran gegen die Pumpenfinger zu verformen. Das kann zum vorzeitigen Nachlassen der Rückstellkräfte führen. Infusionspumpen, wie beispielsweise peristaltische Schlauchpumpen, sollen möglichst klein und leichtgewichtig gebaut werden. Daher ist es wichtig, den Energiebedarf zu verringern, um Bauteile wie Akku, Netzteil und Antriebsmotor möglichst klein zu dimensionieren. Gleichzeitig ist die Forderung nach Einhaltung der angewählten Förderrate, auch während langer Infusionszeiten zu erfüllen.Peristaltic peristaltic pumps are often called infusion or Transfusion pumps for pumping liquid substances in medical Area used. Linear peristaltic pumps are known, where a straight pump hose from numerous pump fingers continuously and cyclically pressed against an abutment is so that the liquid in the pump hose in Direction of conveyance is moved. EP 0 214 443 A1 describes a peristaltic linear peristaltic pump with numerous at one Shaft-mounted eccentric discs. Every eccentric disc carries a ball bearing and acts on a linearly movable pump finger. All pump fingers are covered by a sealing membrane, which is a sealing separation between the drive mechanism and forms the pump hose. This will cause damage and contamination of the pump hose avoided. on the other hand is the inside of the pump against liquid ingress protected. A sealing membrane arranged in this way influences the funding accuracy is negative. It causes a coupling of forces between adjacent pump fingers, which also causes the electrical Energy consumption is increased. Part of the restoring forces the pump hose is required with this membrane arrangement, to deform the sealing membrane against the pump fingers. The can lead to premature release of the restoring forces. Infusion pumps, such as peristaltic peristaltic pumps, should be built as small and lightweight as possible. Therefore, it is important to reduce the energy requirement to components such as battery, power supply and drive motor as small as possible dimension. At the same time, the demand for compliance the selected delivery rate, even during long infusion times to fulfill.

Der Erfindung liegt die Aufgabe zugrunde, eine peristaltische Schlauchpumpe zu schaffen, die kleinformatig hergestellt werden kann, einen geringen Energiebedarf hat und eine gute Fördergenauigkeit bei langen Infusionszeiten hat.The invention has for its object a peristaltic To create peristaltic pumps that are manufactured in small format can, has a low energy requirement and good conveying accuracy with long infusion times.

Die Lösung dieser Aufgabe erfolgt erfindungsgemäß mit den im Anspruch 1 angegebenen Merkmalen. Hiernach sind die Lager auf den Exzenterscheiben der Welle jeweils mit einer Pleuelstange verbunden, welche an einem linear geführten Pumpenfinger angreift. Die Pumpenfinger sind auf der dem Pumpenschlauch zugewandten Seite (Außenseite) der Dichtmembran angeordnet und die Pleuelstangen gehen durch die Dichtmembran hindurch.This object is achieved with the im Claim 1 specified features. After that, the camps are open the eccentric discs of the shaft with a connecting rod connected, which acts on a linearly guided pump finger. The pump fingers are on the side facing the pump hose Side (outside) of the sealing membrane arranged and the Connecting rods go through the sealing membrane.

Dadurch dass die Dichtmembran nicht die Pumpenfinger überspannt, erfolgt keine ständige periodische Dehnung der Dichtmembran zwischen benachbarten Pumpenfingern. Dadurch wird weniger Antriebsenergie benötigt. Die noch benötigten Kräfte, die Membran zu verformen, müssen nicht durch die Rückstellkräfte des Pumpenschlauches aufgebracht werden, sondern werden durch den Pumpenantrieb bereitgestellt. Hierdurch wird die Förderratengenauigkeit über längere Infusionszeiten verbessert. Außerdem wird der Verschleiß der Dichtmembran verringert. Die Verwendung von Pleuelstangen ermöglicht einen einfachen und kleinen Durchgang durch die Dichtmembran. Die Dichtmembran sollte keine gespannte Fläche bilden, sondern eine lose Faltenmembran sein, die sich den Bewegungen der Pleuelstangen anpasst, ohne dass wesentliche Materialspannungen auftreten.Because the sealing membrane does not span the pump fingers, there is no constant periodic expansion of the sealing membrane between adjacent pump fingers. This will make less Drive energy needed. The forces still needed, the The restoring forces do not have to deform the membrane of the pump hose are applied, but are by provided the pump drive. This makes the delivery rate accuracy improved over longer infusion times. Moreover the wear of the sealing membrane is reduced. The usage of connecting rods enables simple and small Passage through the sealing membrane. The sealing membrane should do not form a stretched surface, but a loose fold membrane that adapts to the movements of the connecting rods without that significant material stresses occur.

Durch die Erfindung werden störende Einflüsse der Dichtmembran auf die Fördergenauigkeit verhindert. Die Dichtmembran wird nicht gewalkt und nicht zwischen Pumpenfinger und Pumpenschlauch gequetscht.The invention eliminates interfering influences of the sealing membrane on the conveying accuracy prevented. The sealing membrane is not tumbled and not between pump finger and pump hose crushed.

Gemäß einer bevorzugten Weiterbildung der Erfindung ist vorgesehen, dass die Dichtmembran zu beiden Seiten des Pumpenschlauchs Falten aufweist, die eine Anpassung an die Querbewegungen der Pleuelstange ermöglichen.According to a preferred development of the invention, that the sealing membrane on both sides of the pump hose Has folds that adapt to the transverse movements enable the connecting rod.

Auf der Seite des Pumpenschlauchs ist vorzugsweise eine Führungsplatte mit einem längslaufenden Aufnahmekanal für den Pumpenschlauch und mit Führungskanälen für die Pumpenfinger vorgesehen. Diese Führungsplatte ist zweckmäßigerweise für Reinigungszwecke herausnehmbar.A guide plate is preferably on the side of the pump hose with a longitudinal intake channel for the pump hose and provided with guide channels for the pump fingers. This guide plate is expedient for cleaning purposes removable.

Eine besondere Ausführungsform ist so aufgebaut, dass die Exzenterscheiben der Welle einstückig angeformt sind. Die Welle bildet somit gewissermaßen eine Kurbelwelle. Der äußere Mantel der Exzenterscheiben kann so geformt sein, dass er gleichzeitig die innere Laufbahn eines Kugellagers bildet. An die Kugellageraußenringe, welche ebenfalls in Spritzgusstechnik herstellbar sind, können die Pleuelstangen direkt angeformt werden. Durch diese Gestaltung wird die Anzahl der benötigten Bauteile verringert und die Reibung wird herabgesetzt. Damit ist wiederum ein geringerer Energieverbrauch verbunden.A special embodiment is constructed so that the eccentric discs the shaft are integrally formed. The wave thus forms a crankshaft, so to speak. The outer coat the eccentric disc can be shaped so that it is simultaneously forms the inner raceway of a ball bearing. To the ball bearing outer rings, which can also be manufactured using injection molding technology the connecting rods can be molded directly. With this design, the number of components required is reduced and the friction is reduced. That is again associated with lower energy consumption.

Im Folgenden wird unter Bezugnahme auf die Zeichnungen ein Ausführungsbeispiel der Erfindung näher erläutert.An exemplary embodiment is described below with reference to the drawings the invention explained in more detail.

Es zeigen:

Fig. 1
eine perspektivische Darstellung der Welle mit den Exzenterscheiben und Pleuelstangen, und
Fig. 2
einen Querschnitt durch die peristaltische Schlauchpumpe.
Show it:
Fig. 1
a perspective view of the shaft with the eccentric and connecting rods, and
Fig. 2
a cross section through the peristaltic peristaltic pump.

Die dargestellte Schlauchpumpe weist einen Pumpenschlauch 10 auf, in dem sich die zu pumpende Flüssigkeit befindet. Dieser Schlauch wird durch zahlreiche Pumpenfinger 11 fortlaufend periodisch zusammengedrückt und entlastet, so wie dies in EP 0 214 443 beschrieben ist.The hose pump shown has a pump hose 10 in which the liquid to be pumped is located. This Hose is continuously periodic by numerous pump fingers 11 compressed and relieved, as in EP 0 214 443.

Der Pumpenschlauch 10 ist in einem Aufnahmekanal 12 enthalten, der in einer Führungsplatte 13 gebildet ist. Die Führungsplatte 13 hat parallele Wände 13a, 13b, die den Aufnahmekanal 12 seitlich begrenzen. Der Aufnahmekanal 12 ist mit mehreren Führungskanälen 14 verbunden, in denen jeweils ein Pumpenfinger 11 quer zur Schlauchrichtung geführt ist. Die Führungsplatte 13 ist an einer Frontwand 15 eines Pumpengehäuses 16 befestigt. Das Pumpengehäuse weist eine vorgesetzte Tür auf, die ein Gegenlager 17 zur Abstützung des Pumpenschlauchs 10 bildet. Das Gegenlager 17 weist einen in den Aufnahmekanal 12 hineinragenden Vorsprung 18 auf.The pump hose 10 is contained in a receiving channel 12, which is formed in a guide plate 13. The guide plate 13 has parallel walls 13a, 13b, which the receiving channel 12 laterally limit. The receiving channel 12 has a plurality of guide channels 14 connected, in each of which a pump finger 11 transversely is guided to the hose direction. The guide plate 13 is on a front wall 15 of a pump housing 16 attached. The pump housing has a front door that is a counter bearing 17 forms to support the pump hose 10. The counter bearing 17 has a projection protruding into the receiving channel 12 18 on.

Insgesamt sind etwa zwölf Pumpenfinger 11 vorhanden, die von einem Exzenterantrieb sinusförmig angetrieben sind, wonach die Bewegungen benachbarter Pumpenfinger eine Phasendifferenz haben.There are a total of about twelve pump fingers 11, which by an eccentric drive are driven sinusoidally, after which the Movements of adjacent pump fingers have a phase difference.

Der Antrieb der Pumpenfinger weist eine parallel zum eingelegten Pumpenschlauch 10 verlaufende Welle 20 auf. An dieser sind mehrere Exzenterscheiben 21, eine für jeden Pumpenfinger 11, befestigt. Auf der Exzenterscheibe sitzt ein Kugellager 22, das einen Außenring 23 lagert. Der Außenring 23 ist mit einem Pleuel 24 verbunden, das eine radial zum Außenring 23 abstehende Pleuelstange 25 aufweist. Das Ende der Pleuelstange 25 ist über ein Gelenk 26 mit dem Pumpenfinger 11 verbunden. Während die Welle 20 mit gleichförmiger Geschwindigkeit dreht, verursacht der beschriebene Exzenterantrieb eine sinusförmige Hin- und Herbewegung des Pumpenfingers 11 relativ zu dem Pumpenschlauch 10.The drive of the pump fingers has a parallel to the inserted Pump hose 10 extending shaft 20. At this are several eccentric discs 21, one for each pump finger 11, attached. A ball bearing 22 sits on the eccentric disc an outer ring 23 supports. The outer ring 23 is with a Connecting rod 24 connected, the one protruding radially to the outer ring 23 Connecting rod 25 has. The end of the connecting rod 25 is connected to the pump finger 11 via a joint 26. While the shaft 20 rotates at a uniform speed, causes the eccentric drive described a sinusoidal Back and forth movement of the pump finger 11 relative to the pump hose 10th

Figur 1 zeigt die verschiedenen Positionen der Pleuelstangen 25 bei einer bestimmten Drehposition der Welle 20. Die Pleuelstangen 25 bilden eine Periode einer Sinuskurve. FIG. 1 shows the different positions of the connecting rods 25 at a certain rotational position of the shaft 20. The connecting rods 25 form a period of a sine curve.

Das Kugellager 22 weist im vorliegenden Fall einen Innenring 22a, einen Außenring 22b und dazwischen angeordnete Kugeln 22c auf, die in einem (nicht dargestellten) Kugelkäfig enthalten sind. Bei einer abgewandelten Ausführungsform ist das Kugellager 22 nicht mit einem eigenen Innenring 22a und einem eigenen Außenring 22b versehen. Der Innenring wird vielmehr unmittelbar von der Exzenterscheibe 21 gebildet. Der Außenring des Kugellagers wird von dem Außenring 23 des Pleuels 24 gebildet. Als Kugellager werden vorzugsweise Kunststoff-Kugellager verwendet.The ball bearing 22 has an inner ring in the present case 22a, an outer ring 22b and balls 22c arranged between them on contained in a (not shown) ball cage are. In a modified embodiment, the ball bearing 22 not with its own inner ring 22a and its own Outer ring 22b provided. The inner ring becomes rather immediate formed by the eccentric disc 21. The outer ring of the ball bearing is formed by the outer ring 23 of the connecting rod 24. As a ball bearing plastic ball bearings are preferably used.

Zwischen dem Exzenterantrieb und den Pumpenfingern 11 befindet sich eine Dichtmembran 27, die sich in Längsrichtung des Aufnahmekanals 12 erstreckt und mit ihren längslaufenden Rändern 27a, 27b an der Rückseite der Gehäusewand 15 befestigt ist, so dass die die Führungsplatte enthaltende Öffnung durch die Dichtmembran 27 verschlossen ist. Die Dichtmembran weist abgedichtete Durchgänge 29 für jede Pleuelstange 25 auf. Die Pleuelstangen 25 sind zylindrisch und mit rundem Querschnitt, so dass die Abdichtung relativ einfach durchzuführen ist. Die Breite der Dichtmembran 27 ist größer als die Breite der Öffnung 30 der Gehäusewand 15, so dass sich beidseitig der Pleuelstange 25 Falten 31 ergeben. Die Dichtmembran 27 ist nicht straff gespannt sondern bildet eine Faltenstruktur. Die Dichtmembran 27 verhindert, dass Flüssigkeit in das Innere des Gehäuses 16 eindringt. Die Führungsplatte 13 kann nach dem Öffnen der Tür zu Reinigungszwecken herausgenommen werden. Ebenso können die einzelnen Pumpenfinger leicht von den Pleuelstangen 25 abgenommen werden.Is located between the eccentric drive and the pump fingers 11 there is a sealing membrane 27 which extends in the longitudinal direction of the receiving channel 12 extends and with their longitudinal edges 27a, 27b is attached to the rear of the housing wall 15, so that the opening containing the guide plate through the Sealing membrane 27 is closed. The sealing membrane has sealed Passages 29 for each connecting rod 25. The connecting rods 25 are cylindrical and with a round cross-section, see above that the sealing is relatively easy to do. The Width of the sealing membrane 27 is larger than the width of the opening 30 of the housing wall 15, so that the connecting rod is on both sides 25 folds 31 result. The sealing membrane 27 is not taut but forms a fold structure. The sealing membrane 27 prevents liquid from getting inside the case 16 penetrates. The guide plate 13 can after opening the door can be removed for cleaning purposes. You can also the individual pump fingers easily from the connecting rods 25 be removed.

Da die Dichtmembran 27 praktisch keine Kraft auf den Pumpenfinger 11 oder die Pleuelstange 25 ausübt, hat die Schlauchpumpe einen geringen Energieverbrauch. Dieser wird durch die Verwendung des Kugellagers 22, das sehr geringe Reibungsverluste hat, noch begünstigt.Since the sealing membrane 27 practically no force on the pump finger 11 or the connecting rod 25 has the hose pump low energy consumption. This is due to the use the ball bearing 22, which has very low friction losses, still favored.

Claims (7)

Peristaltische Schlauchpumpe mit einer Welle (20), die mehrere Exzenterscheiben (21) aufweist, von denen jede ein Lager (22) trägt und damit einen Pumpenfinger (11) quer zu einem Pumpenschlauch (10) bewegt, und mit einer zwischen der Welle (20) und dem Pumpenschlauch (10) angeordneten Dichtmembran (27),
dadurch gekennzeichnet, dass die Lager (22) jeweils mit einer Pleuelstange (25) verbunden sind, welche an einem linear geführten Pumpenfinger (11) angreift, und dass die Pumpenfinger (11) auf der dem Pumpenschlauch (10) zugewandten Seite der Dichtmembran (27) angeordnet sind und die Pleuelstangen (25) durch die Dichtmembran (27) hindurchgehen.Peristaltic peristaltic pump with a shaft (20) which has a plurality of eccentric discs (21), each of which carries a bearing (22) and thus moves a pump finger (11) transversely to a pump hose (10), and with one between the shaft (20 ) and the pump hose (10) arranged sealing membrane (27),
characterized in that the bearings (22) are each connected to a connecting rod (25) which engages a linearly guided pump finger (11) and that the pump fingers (11) on the side of the sealing membrane (27) facing the pump hose (10) ) are arranged and the connecting rods (25) pass through the sealing membrane (27). Schlauchpumpe nach Anspruch 1, dadurch gekennzeichnet, dass die Dichtmembran (27) seitliche Falten (31) aufweist, die eine Anpassung an die Querbewegungen der Pleuelstange (25) ermöglichen.Peristaltic pump according to claim 1, characterized in that the sealing membrane (27) has lateral folds (31) which allow adaptation to the transverse movements of the connecting rod (25). Schlauchpumpe nach Anspruch 1 oder 2, dadurch gekennzeichnet, dass eine Führungsplatte (13) mit einem längslaufenden Aufnahmekanal (12) für den Pumpenschlauch (10) und Führungskanälen (14) für die Pumpenfinger (11) herausnehmbar an einem Gehäuse (16) befestigt ist.Peristaltic pump according to claim 1 or 2, characterized in that a guide plate (13) with a longitudinal receiving channel (12) for the pump hose (10) and guide channels (14) for the pump fingers (11) is removably attached to a housing (16). Schlauchpumpe nach Anspruch 3, dadurch gekennzeichnet, dass ein Gegenlager (17) zum Abstützen des Pumpenschlauchs (10) einen in den Aufnahmekanal (12) ragenden Vorsprung (18) aufweist.Hose pump according to claim 3, characterized in that a counter bearing (17) for supporting the pump hose (10) has a projection (18) projecting into the receiving channel (12). Schlauchpumpe nach einem der Ansprüche 1-4, dadurch gekennzeichnet, dass die Exzenterscheiben (21) der Welle (20) einstückig angeformt sind.Peristaltic pump according to one of claims 1-4, characterized in that the eccentric discs (21) of the shaft (20) are integrally formed. Schlauchpumpe nach einem der Ansprüche 1-5, dadurch gekennzeichnet, dass die Exzenterscheiben (21) die Innenringe von Kugellagern (22) bilden.Peristaltic pump according to one of claims 1-5, characterized in that the eccentric discs (21) form the inner rings of ball bearings (22). Schlauchpumpe nach einem der Ansprüche 1-6, dadurch gekennzeichnet, dass die Pleuelstange (25) einen das Lager (20) umgebenden Außenring (23) aufweist.Peristaltic pump according to one of claims 1-6, characterized in that the connecting rod (25) has an outer ring (23) surrounding the bearing (20).
EP03014680A 2002-07-06 2003-06-27 Peristaltic pump Expired - Lifetime EP1378663B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE20210502U DE20210502U1 (en) 2002-07-06 2002-07-06 Peristaltic peristaltic pump
DE20210502U 2002-07-06

Publications (3)

Publication Number Publication Date
EP1378663A2 true EP1378663A2 (en) 2004-01-07
EP1378663A3 EP1378663A3 (en) 2005-01-05
EP1378663B1 EP1378663B1 (en) 2011-05-25

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EP03014680A Expired - Lifetime EP1378663B1 (en) 2002-07-06 2003-06-27 Peristaltic pump

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US (1) US7217108B2 (en)
EP (1) EP1378663B1 (en)
JP (1) JP4235501B2 (en)
CN (1) CN100394026C (en)
AT (1) ATE511021T1 (en)
AU (1) AU2003204825B2 (en)
CA (1) CA2432774C (en)
DE (1) DE20210502U1 (en)
ES (1) ES2366946T3 (en)

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JP4235501B2 (en) 2009-03-11
CA2432774A1 (en) 2004-01-06
AU2003204825A1 (en) 2004-01-22
EP1378663A3 (en) 2005-01-05
ES2366946T3 (en) 2011-10-26
CN100394026C (en) 2008-06-11
CN1474054A (en) 2004-02-11
US20040037723A1 (en) 2004-02-26
DE20210502U1 (en) 2003-11-20
US7217108B2 (en) 2007-05-15
JP2004036620A (en) 2004-02-05
ATE511021T1 (en) 2011-06-15
CA2432774C (en) 2010-09-07
EP1378663B1 (en) 2011-05-25
AU2003204825B2 (en) 2008-12-11

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